meperidine has been researched along with Labor Pain in 43 studies
Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.
Labor Pain: Pain associated with OBSTETRIC LABOR in CHILDBIRTH. It is caused primarily by UTERINE CONTRACTION as well as pressure on the CERVIX; BLADDER; and the GASTROINTESTINAL TRACT. Labor pain mostly occurs in the ABDOMEN; the GROIN; and the BACK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to evaluate the evidence regarding the efficacy and safety of meperidine for acute postoperative and labor pain." | 9.05 | Analgesic Efficacy and Adverse Effects of Meperidine in Managing Postoperative or Labor Pain: A Narrative Review of Randomized Controlled Trials. ( Cheung, CW; Ching Wong, SS, 2020) |
| "The aim of this study was to evaluate the evidence regarding the efficacy and safety of meperidine for acute postoperative and labor pain." | 5.05 | Analgesic Efficacy and Adverse Effects of Meperidine in Managing Postoperative or Labor Pain: A Narrative Review of Randomized Controlled Trials. ( Cheung, CW; Ching Wong, SS, 2020) |
| "Compared with meperidine, remifentanil is superior in reducing mean VAS scores for labor pain after 1 hour." | 4.87 | A comparison between remifentanil and meperidine for labor analgesia: a systematic review. ( Leong, WL; Sia, AT; Sng, BL, 2011) |
| " Proper management of the untoward effects of this method may introduce it as a safe and low-cost method for painless labor." | 2.80 | Efficacy and Safety of Sufentanil and Pethidine in Spinal Anesthesia for Painless Labor. ( Bagheri, B; Farzanegan, B; Fathi, M; Salarian, S, 2015) |
| "Fentanyl appears to be a suitable alternative to pethidine when providing parenteral pain relief to labouring women." | 2.80 | A comparison of fentanyl with pethidine for pain relief during childbirth: a randomised controlled trial. ( Belan, I; Cyna, AM; Fleet, J; Jones, MJ; Ullah, S, 2015) |
| "This trial aimed to ascertain the relative efficacy, adverse effects, and acceptability of fentanyl versus pethidine for pain relief during labour." | 2.80 | The safety and acceptability of intravenous fentanyl versus intramuscular pethidine for pain relief during labour. ( Dawood, R; El-Shamy, ES; Habeeb, R; Massod, A; Rezk, M, 2015) |
| " Maternal adverse effects of Pethilorfan were generally mild and transient." | 1.51 | Safety and efficacy of a combination of pethidine and levallorphan for pain relief during labor: An observational study. ( Kinugasa, M; Miyake, M; Tamai, H; Tamura, M, 2019) |
| "Labor pain is probably the most painful event in a woman's life." | 1.39 | Timing of epidural analgesia intervention for labor pain in nulliparous women in Taiwan: a retrospective study. ( Chang, Y; Chen, YL; Yeh, YL, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (9.30) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (13.95) | 29.6817 |
| 2010's | 28 (65.12) | 24.3611 |
| 2020's | 5 (11.63) | 2.80 |
| Authors | Studies |
|---|---|
| Chantrasiri, R | 1 |
| Wanapirak, C | 1 |
| Tongsong, T | 1 |
| Lai, CY | 1 |
| Wong, MKW | 1 |
| Tong, WH | 1 |
| Lau, KY | 1 |
| Chu, SY | 1 |
| Tam, AML | 1 |
| Hui, LL | 1 |
| Lao, TTH | 1 |
| Leung, TY | 1 |
| Moran, VH | 1 |
| Thomson, G | 1 |
| Cook, J | 1 |
| Storey, H | 1 |
| Beeson, L | 2 |
| MacArthur, C | 4 |
| Wilson, M | 2 |
| Ching Wong, SS | 1 |
| Cheung, CW | 1 |
| Anter, ME | 1 |
| Abdel Attey Saleh, S | 1 |
| Shawkey Allam, S | 1 |
| Mohamed Nofal, A | 1 |
| Kadirogullari, P | 1 |
| Yalcin Bahat, P | 1 |
| Sahin, B | 1 |
| Gonen, I | 1 |
| Seckin, KD | 1 |
| Fleet, JA | 1 |
| Jones, M | 1 |
| Belan, I | 2 |
| Smith, LA | 1 |
| Burns, E | 1 |
| Cuthbert, A | 1 |
| Wilson, MJA | 2 |
| Hewitt, CA | 1 |
| Handley, K | 2 |
| Gao, F | 1 |
| Daniels, J | 3 |
| Kinugasa, M | 1 |
| Miyake, M | 1 |
| Tamai, H | 1 |
| Tamura, M | 1 |
| Logtenberg, S | 1 |
| Mol, BW | 1 |
| Verhoeven, C | 1 |
| Miles, ETC | 1 |
| Stone, JP | 1 |
| Lozada, MJ | 1 |
| Weiniger, CF | 1 |
| Carvalho, B | 1 |
| Bauchat, JR | 1 |
| Wang, L | 1 |
| Wei, L | 1 |
| Deng, X | 1 |
| Leung, RW | 1 |
| Li, JF | 1 |
| Leung, MK | 1 |
| Fung, BK | 1 |
| Fung, LC | 1 |
| Tai, SM | 1 |
| Sing, C | 1 |
| Leung, WC | 1 |
| Chen, YL | 1 |
| Chang, Y | 1 |
| Yeh, YL | 1 |
| Wee, MY | 3 |
| Tuckey, JP | 3 |
| Thomas, PW | 2 |
| Burnard, S | 3 |
| Salarian, S | 1 |
| Fathi, M | 1 |
| Farzanegan, B | 1 |
| Bagheri, B | 1 |
| Eichelberger, KY | 1 |
| Leung, EY | 1 |
| Wee, M | 1 |
| Montgomery, A | 1 |
| Whittaker, V | 1 |
| Banerjee, S | 1 |
| Fleet, J | 1 |
| Jones, MJ | 1 |
| Ullah, S | 1 |
| Cyna, AM | 1 |
| Solek-Pastuszka, J | 1 |
| Zagrodnik-Ulan, E | 1 |
| Bohatyrewicz, R | 1 |
| Celewicz, Z | 1 |
| Rezk, M | 1 |
| El-Shamy, ES | 1 |
| Massod, A | 1 |
| Dawood, R | 1 |
| Habeeb, R | 1 |
| Gao Smith, F | 1 |
| Homer, L | 1 |
| Aziato, L | 1 |
| Acheampong, AK | 1 |
| Umoar, KL | 1 |
| Weissman, A | 1 |
| Torkhov, O | 1 |
| Weissman, AI | 1 |
| Drugan, A | 1 |
| Borup, L | 1 |
| Wurlitzer, W | 1 |
| Hedegaard, M | 1 |
| Kesmodel, US | 1 |
| Hvidman, L | 1 |
| Thomas, P | 1 |
| Leong, WL | 1 |
| Sng, BL | 1 |
| Sia, AT | 1 |
| Elbohoty, AE | 1 |
| Abd-Elrazek, H | 1 |
| Abd-El-Gawad, M | 1 |
| Salama, F | 1 |
| El-Shorbagy, M | 1 |
| Abd-El-Maeboud, KH | 1 |
| Novikova, N | 1 |
| Cluver, C | 1 |
| Rooks, JP | 1 |
| NOACK, H | 1 |
| LEHRER, I | 1 |
| BENGEL, T | 1 |
| UHER, W | 1 |
| DEKORNFELD, TJ | 1 |
| PEARSON, JW | 1 |
| LASAGNA, L | 1 |
| ABE, T | 1 |
| Sosa, CG | 1 |
| Buekens, P | 1 |
| Hughes, JM | 1 |
| Balaguer, E | 1 |
| Sotero, G | 1 |
| Panizza, R | 1 |
| Piriz, H | 1 |
| Alonso, JG | 1 |
| Jantjes, L | 1 |
| Strümpher, J | 1 |
| Kotzé, WJ | 1 |
| Onah, HE | 1 |
| Obi, SN | 1 |
| Oguanuo, TC | 1 |
| Ezike, HA | 1 |
| Ogbuokiri, CM | 1 |
| Ezugworie, JO | 1 |
| Chuntharapat, S | 1 |
| Petpichetchian, W | 1 |
| Hatthakit, U | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Intravenous Paracetamol in Manament of Labour Pain in a Low Resource Setting[NCT04744727] | 96 participants (Actual) | Interventional | 2019-03-01 | Completed | |||
| The Effect of Pethidine Analgesia on Labor Duration and Maternal-Fetal Outcomes[NCT03882814] | 240 participants (Actual) | Observational | 2017-07-01 | Completed | |||
| [NCT02493192] | Phase 4 | 110 participants (Anticipated) | Interventional | 2015-07-31 | Not yet recruiting | ||
| Pethidine Versus Nitrous Oxide for Pain Relief During Labor Among Multiparous. A Randomized Controlled Trial[NCT02783508] | 214 participants (Actual) | Interventional | 2016-08-31 | Completed | |||
| Auricular Acupuncture as Adjunct for Pain Management During First Trimester Uterine Aspiration.[NCT03391986] | 153 participants (Actual) | Interventional | 2017-09-09 | Completed | |||
| Is There Any Effect of Meperidine on the Length of Duration of Labor? A Prospective Randomized Controlled Trial.[NCT01555671] | Phase 4 | 250 participants (Actual) | Interventional | 2012-01-01 | Completed | ||
| Interest in Clonidine in Association With Levobupivacaine Performing a Pudendal Block in Proctological Surgery: Pilot Study, Prospective[NCT04530903] | Phase 4 | 30 participants (Anticipated) | Interventional | 2020-09-09 | Recruiting | ||
| Impact of Prenatal Yoga Practice on Birth Outcome[NCT03941041] | 210 participants (Anticipated) | Interventional | 2019-05-15 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Measure effectiveness of placebo as an adjunct to ibuprofen and paracervical block for pain control during uterine aspiration by comparing the maximum pain score; as measured by VAS between women randomized to receive placebo adhesives and routine care controls - using a 100 mm visual analog scale (VAS-P) (anchors: 0 mm = no pain, 100 mm = worst pain in my life). (NCT03391986)
Timeframe: prior to the procedure (baseline), at the completion of the procedure (approximately 10 minutes later)
| Intervention | score on a scale (Mean) |
|---|---|
| Placebo Adhesives | 70.0 |
| Routine Care | 71.0 |
Using a satisfaction survey (investigator-developed, 6 questions, each question is graded on a scale of 1-5, 1 being very poor and 5 being very good) to measure effectiveness of auricular acupuncture for improving satisfaction. (NCT03391986)
Timeframe: at the completion of the procedure (approximately 5-10 minutes)
| Intervention | percentage of participants (Number) |
|---|---|
| Pyonex Needles | 94 |
| Routine Care | 76 |
Measure effectiveness of auricular acupuncture as an adjunct to ibuprofen and paracervical block for pain control during first trimester uterine aspiration by comparing the maximum pain score; as measured by VAS between women randomized to receive auricular acupuncture and routine care controls - using a 100 mm visual analog scale (VAS-P) (anchors: 0 mm = no pain, 100 mm = worst pain in my life). The VAS has no sub-scales. (NCT03391986)
Timeframe: at the completion of the procedure (approximately 10 minutes later)
| Intervention | score on a scale (Mean) |
|---|---|
| Pyonex Needles | 39.5 |
| Routine Care | 71.0 |
The period of time until the birth of the baby, since the patient being followed for delivery (NCT01555671)
Timeframe: 24h
| Intervention | minutes (Mean) |
|---|---|
| Meperidine Administration Group | 24 |
| Plasebo Group | 27 |
The primary outcome is to evaluate whether meperidine is effective in shortening the duration of the active phase of labor (NCT01555671)
Timeframe: 24h
| Intervention | minutes (Mean) |
|---|---|
| Meperidine Administration Group | 249 |
| Plasebo Group | 304 |
Total time of delivery of patients who gave birth including the second stage of delivery (NCT01555671)
Timeframe: 24h
| Intervention | minutes (Mean) |
|---|---|
| Meperidine Administration Group | 273 |
| Plasebo Group | 331 |
6 reviews available for meperidine and Labor Pain
| Article | Year |
|---|---|
Analgesic Efficacy and Adverse Effects of Meperidine in Managing Postoperative or Labor Pain: A Narrative Review of Randomized Controlled Trials.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Cesarean Section; Female; Humans; Labor Pa | 2020 |
Parenteral opioids for maternal pain management in labour.
Topics: Analgesia, Obstetrical; Analgesics, Opioid; Female; Humans; Injections, Intramuscular; Injections, I | 2018 |
Remifentanil for labour pain relief.
Topics: Analgesia, Obstetrical; Analgesics, Opioid; Female; Humans; Labor Pain; Meperidine; Pain Measurement | 2015 |
A comparison between remifentanil and meperidine for labor analgesia: a systematic review.
Topics: Analgesia, Obstetrical; Analgesics, Opioid; Female; Humans; Labor Pain; Meperidine; Odds Ratio; Pain | 2011 |
Local anaesthetic nerve block for pain management in labour.
Topics: Anesthesia, Obstetrical; Anesthetics, Local; Female; Fentanyl; Humans; Labor Pain; Meperidine; Nerve | 2012 |
Labor pain management other than neuraxial: what do we know and where do we go next?
Topics: Analgesia, Obstetrical; Analgesics; Analgesics, Opioid; Female; Humans; Labor Pain; Labor, Obstetric | 2012 |
17 trials available for meperidine and Labor Pain
| Article | Year |
|---|---|
Entonox
Topics: Analgesics, Opioid; Cesarean Section; Female; Humans; Infant, Newborn; Labor Pain; Meperidine; Nitro | 2021 |
The impact of antenatal massage practice on intrapartum massage application and their associations with the use of analgesics during labour : Sub-analysis of a randomised control trial.
Topics: Analgesia, Epidural; Analgesia, Obstetrical; Analgesics; Female; Humans; Labor Pain; Labor, Obstetri | 2022 |
Qualitative exploration of women's experiences of intramuscular pethidine or remifentanil patient-controlled analgesia for labour pain.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Breast Feeding; Female; Follow-Up Studies; | 2019 |
Efficacy and safety of intravenous paracetamol in management of labour pains in a low resource setting: a randomized clinical trial.
Topics: Acetaminophen; Analgesia, Obstetrical; Analgesics; Analgesics, Opioid; Dizziness; Double-Blind Metho | 2022 |
Taking the alternative route: Women's experience of intranasal fentanyl, subcutaneous fentanyl or intramuscular pethidine for labour analgesia.
Topics: Administration, Intranasal; Adult; Analgesics; Drug-Related Side Effects and Adverse Reactions; Fema | 2017 |
Intravenous remifentanil patient-controlled analgesia versus intramuscular pethidine for pain relief in labour (RESPITE): an open-label, multicentre, randomised controlled trial.
Topics: Administration, Intravenous; Adolescent; Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analges | 2018 |
A comparison of intramuscular diamorphine and intramuscular pethidine for labour analgesia: a two-centre randomised blinded controlled trial.
Topics: Adolescent; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Double-Blind Method; Drug Administrat | 2014 |
Efficacy and Safety of Sufentanil and Pethidine in Spinal Anesthesia for Painless Labor.
Topics: Adult; Analgesics, Opioid; Anesthesia, Spinal; Female; Humans; Labor Pain; Meperidine; Pregnancy; Su | 2015 |
A comparison of fentanyl with pethidine for pain relief during childbirth: a randomised controlled trial.
Topics: Administration, Intranasal; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Delivery, Obstetric; | 2015 |
The safety and acceptability of intravenous fentanyl versus intramuscular pethidine for pain relief during labour.
Topics: Analgesics, Opioid; Apgar Score; Female; Fentanyl; Humans; Infant, Newborn; Infusions, Intravenous; | 2015 |
The RESPITE trial: remifentanil intravenously administered patient-controlled analgesia (PCA) versus pethidine intramuscular injection for pain relief in labour: study protocol for a randomised controlled trial.
Topics: Adult; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesics, Opioid; Clinical Protocols | 2016 |
The effects of meperidine and epidural analgesia in labor on maternal heart rate variability.
Topics: Adjuvants, Anesthesia; Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Local; Antie | 2009 |
Acupuncture as pain relief during delivery: a randomized controlled trial.
Topics: Acupuncture Analgesia; Adult; Analgesia, Epidural; Analgesics; Female; Humans; Hydrotherapy; Labor P | 2009 |
The IDvIP trial: a two-centre randomised double-blind controlled trial comparing intramuscular diamorphine and intramuscular pethidine for labour analgesia.
Topics: Analgesia, Obstetrical; Analgesics, Opioid; Apgar Score; Cardiotocography; Double-Blind Method; Feed | 2011 |
Intravenous infusion of paracetamol versus intravenous pethidine as an intrapartum analgesic in the first stage of labor.
Topics: Acetaminophen; Analgesia, Obstetrical; Analgesics, Non-Narcotic; Analgesics, Opioid; Female; Humans; | 2012 |
Effect of pethidine administered during the first stage of labor on the acid-base status at birth.
Topics: Acid-Base Equilibrium; Acidosis; Analgesics, Opioid; Female; Fetal Blood; Hospitals, Public; Humans; | 2006 |
Yoga during pregnancy: effects on maternal comfort, labor pain and birth outcomes.
Topics: Adolescent; Adult; Analgesics, Opioid; Apgar Score; Female; Humans; Labor Pain; Labor Stage, First; | 2008 |
20 other studies available for meperidine and Labor Pain
| Article | Year |
|---|---|
The Effect of Pethidine Analgesia on Labor Duration and Maternal-Fetal Outcomes.
Topics: Analgesia, Obstetrical; Analgesics, Opioid; Female; Humans; Infant, Newborn; Labor Pain; Meperidine; | 2021 |
Safety and efficacy of a combination of pethidine and levallorphan for pain relief during labor: An observational study.
Topics: Analgesia, Obstetrical; Analgesics, Opioid; Drug Combinations; Female; Humans; Infant, Newborn; Labo | 2019 |
Pain relief during labour.
Topics: Analgesia, Patient-Controlled; Female; Humans; Labor Pain; Labor, Obstetric; Meperidine; Pregnancy; | 2019 |
Pain relief during labour.
Topics: Analgesia, Patient-Controlled; Female; Humans; Labor Pain; Labor, Obstetric; Meperidine; Pregnancy; | 2019 |
Pain relief during labour.
Topics: Analgesia, Patient-Controlled; Female; Humans; Labor Pain; Labor, Obstetric; Meperidine; Pregnancy; | 2019 |
Pain relief during labour.
Topics: Analgesia, Patient-Controlled; Female; Humans; Labor Pain; Labor, Obstetric; Meperidine; Pregnancy; | 2019 |
Pain relief during labour - Authors' reply.
Topics: Analgesia, Patient-Controlled; Female; Humans; Labor Pain; Labor, Obstetric; Meperidine; Pregnancy; | 2019 |
Efficacy of birth ball exercises on labour pain management.
Topics: Adult; Analgesics, Opioid; Anxiety; Delivery, Obstetric; Exercise Therapy; Female; Hong Kong; Humans | 2013 |
Timing of epidural analgesia intervention for labor pain in nulliparous women in Taiwan: a retrospective study.
Topics: Adult; Analgesia, Epidural; Cesarean Section; Female; Humans; Labor Pain; Meperidine; Parity; Pregna | 2013 |
A report from #BlueJC: does choice of intramuscular analgesics in labour matter?
Topics: Analgesia, Obstetrical; Analgesics, Opioid; Female; Heroin; Humans; Labor Pain; Meperidine; Pregnanc | 2014 |
Author's reply to '#BlueJC: does choice of intramuscular analgesics in labour matter?'.
Topics: Analgesia, Obstetrical; Analgesics, Opioid; Female; Heroin; Humans; Labor Pain; Meperidine; Pregnanc | 2014 |
Authors' reply: A comparison of intramuscular diamorphine and intramuscular pethidine for labour analgesia: a two-centre randomised blinded controlled trial.
Topics: Analgesia, Obstetrical; Analgesics, Opioid; Female; Heroin; Humans; Labor Pain; Meperidine; Pregnanc | 2014 |
A comparison of intramuscular diamorphine and intramuscular pethidine for labour analgesia: a two-centre randomised blinded controlled trial.
Topics: Analgesia, Obstetrical; Analgesics, Opioid; Female; Heroin; Humans; Labor Pain; Meperidine; Pregnanc | 2014 |
Labour pain experiences and perceptions: a qualitative study among post-partum women in Ghana.
Topics: Adult; Analgesia, Obstetrical; Analgesics, Opioid; Attitude to Health; Breathing Exercises; Female; | 2017 |
[Problem of dosage of dolantin & negaphen in alleviation of labor pains].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Chlorpromazine; Female; Humans; Labor Pain; Labor, | 1958 |
[Medical alleviation of labor pains with a thioxanthine derivative].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesia, Obstetrical; Female; Labor Pain; Meperi | 1962 |
METHOTRIMEPRAZINE IN THE TREATMENT OF LABOR PAIN.
Topics: Anesthesia; Anesthesia, Obstetrical; Female; Humans; Labor Pain; Meperidine; Methotrimeprazine; Obst | 1964 |
[ON RECENT TECHNICS FOR THE RELIEF OF LABOR PAINS, WITH SPECIAL REFERENCE TO PAIN RELIEF BY DRUGS].
Topics: Analgesics; Analgesics, Non-Narcotic; Anesthesia; Anesthesia, Obstetrical; Antipyretics; Autonomic N | 1964 |
The experience of childbrith in first-time mothers who received narcotic analgesics during the first stage of labour.
Topics: Adaptation, Psychological; Analgesia, Obstetrical; Analgesics, Opioid; Attitude to Health; Drug Ther | 2007 |
Pain perception among parturients in Enugu, South-eastern Nigeria.
Topics: Adolescent; Adult; Analgesia, Obstetrical; Cross-Sectional Studies; Female; Humans; Labor Pain; Labo | 2007 |