Page last updated: 2024-10-30

meperidine and Kidney Diseases

meperidine has been researched along with Kidney Diseases in 24 studies

Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
"Meperidine 50 mg was superior to tramadol 50 mg for acute pain relief in patients with suspected renal colic when given intravenously."2.70Intravenous single-dose tramadol versus meperidine for pain relief in renal colic. ( Akça, S; Cete, N; Cete, Y; Eray, O; Ersoy, F; Karsli, B; Oktay, C, 2002)
"Because of the well known adverse effects that may be associated with pethidine use, the authors recommend that morphine should be the preferred agent in suspected renal colic, when an opioid analgesic is to be used."2.69A comparison of the efficacy and safety of morphine and pethidine as analgesia for suspected renal colic in the emergency setting. ( Cardwell, H; O'Connor, A; Schug, SA, 2000)
" The time to first administration of rescue analgesic, up to 24 h following dosing with the study medication, was recorded."2.67A comparison of intramuscular ketorolac and pethidine in the alleviation of renal colic. ( Arkell, DG; Fletcher, MS; Iacovou, JW; Kaisary, AV; Philip, NH; Sandhu, DP, 1994)
"Diclofenac sodium is a valid alternative, which shows similar analgesic efficacy."2.67Comparative study of the efficacy of dipyrone, diclofenac sodium and pethidine in acute renal colic. Collaborative Group of the Spanish Society of Clinical Pharmacology. ( , 1991)
" The mean +/- SEM elimination half-life (t1/2) of pethidine was significantly longer in the three groups of renal patients: 7."1.27Pharmacokinetics of low-dose intravenous pethidine in patients with renal dysfunction. ( Chan, K; Jennings, F; Orme, ML; Tse, J, 1987)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199010 (41.67)18.7374
1990's9 (37.50)18.2507
2000's5 (20.83)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Muñoz Ruiz, AI1
Guerrero Vega, E1
Maldonado Castro, G1
de Diego Pozas, P1
Marcos Sánchez, F1
Durán Pérez-Navarro, A1
Kastner, C1
Tagg, A1
JACOBSEN, P1
Kelm-Kahl, I1
Stark, E1
Steffens, J1
Curry, C1
Kelly, AM2
Sandhu, DP1
Iacovou, JW1
Fletcher, MS1
Kaisary, AV1
Philip, NH1
Arkell, DG1
Cordell, WH1
Wright, SW1
Wolfson, AB1
Timerding, BL1
Maneatis, TJ1
Lewis, RH1
Bynum, L1
Nelson, DR1
Bergus, GR1
Laerum, E1
Ommundsen, OE1
Grønseth, JE1
Christiansen, A1
Fagertun, HE1
al-Sahlawi, KS1
Tawfik, OM1
Ginifer, C1
O'Connor, A1
Schug, SA1
Cardwell, H1
Eray, O1
Cete, Y1
Oktay, C1
Karsli, B1
Akça, S1
Cete, N1
Ersoy, F1
Oosterlinck, W1
Philp, NH2
Charig, C1
Gillies, G1
Hetherington, JW2
Lloyd, J1
Thompson, JF1
Pike, JM1
Chumas, PD1
Rundle, JS1
Sommer, P1
Kromann-Andersen, B1
Lendorf, A1
Lyngdorf, P1
Møller, P1
Wood, M1
Zhang, XT1
Zhang, YE1
Henry, HH1
Henry, H1
Nordan, J1
Tomlin, EM1
Chan, K1
Tse, J1
Jennings, F1
Orme, ML1
Johnson, R1
Douglas, J1
Corey, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Trial Comparing the Combination of Intravenous Lidocaine and Ketorolac to Either Analgesics Alone for ED Patients With Acute Renal Colic[NCT02902770]Phase 4150 participants (Actual)Interventional2016-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Pain Score at 30 Minutes

The trial will compare the patient's pain score on a 11 point Likert scale, ranging from 0 to 10 with 0 being no pain, 5 moderate pain and 10 very severe pain, at 30 minutes (NCT02902770)
Timeframe: 30 minutes

Interventionscore on a scale (Mean)
Lidocaine and Normal Saline Push5.52
Ketorolac and Normal Saline Drip3.88
Lidocaine and Ketorolac3.14

Reviews

2 reviews available for meperidine and Kidney Diseases

ArticleYear
Improving the effectiveness of the emergency management of renal colic in a district general hospital: a completed audit cycle.
    Emergency medicine journal : EMJ, 2003, Volume: 20, Issue:5

    Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Colic; Diclofenac; Drug Administration

2003
Plasma drug binding: implications for anesthesiologists.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:7

    Topics: Age Factors; Alfentanil; Alprenolol; Anesthesia; Anesthetics; Blood Proteins; Bupivacaine; Burns; Ca

1986

Trials

16 trials available for meperidine and Kidney Diseases

ArticleYear
Intravenous tenoxicam for the treatment of renal colic.
    The New Zealand medical journal, 1995, Jun-14, Volume: 108, Issue:1001

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Colic; Double-Blind Method; Female

1995
A comparison of intramuscular ketorolac and pethidine in the alleviation of renal colic.
    British journal of urology, 1994, Volume: 74, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Colic; Double-B

1994
Comparison of intravenous ketorolac, meperidine, and both (balanced analgesia) for renal colic.
    Annals of emergency medicine, 1996, Volume: 28, Issue:2

    Topics: Adult; Aged; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Colic; Double-Blind Method; Dr

1996
Pain relief for renal colic.
    The Journal of family practice, 1996, Volume: 43, Issue:5

    Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Colic; Double-Blind Method; Drug

1996
Intramuscular diclofenac versus intravenous indomethacin in the treatment of acute renal colic.
    European urology, 1996, Volume: 30, Issue:3

    Topics: Acute Disease; Adult; Analgesics, Opioid; Colic; Cyclooxygenase Inhibitors; Diclofenac; Female; Huma

1996
Comparative study of the efficacy of lysine acetylsalicylate, indomethacin and pethidine in acute renal colic.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 1996, Volume: 3, Issue:3

    Topics: Adult; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colic; Doub

1996
Administration of rectal indomethacin does not reduce the requirement for intravenous narcotic analgesia in acute renal colic.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 1996, Volume: 3, Issue:2

    Topics: Acute Disease; Administration, Rectal; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal;

1996
A comparison of the efficacy and safety of morphine and pethidine as analgesia for suspected renal colic in the emergency setting.
    Journal of accident & emergency medicine, 2000, Volume: 17, Issue:4

    Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Colic; Emergency Service, Hospital; Humans; Kidney Dise

2000
Intravenous single-dose tramadol versus meperidine for pain relief in renal colic.
    European journal of anaesthesiology, 2002, Volume: 19, Issue:5

    Topics: Adult; Analgesics, Opioid; Colic; Double-Blind Method; Female; Humans; Injections, Intravenous; Kidn

2002
Comparative study of the efficacy of dipyrone, diclofenac sodium and pethidine in acute renal colic. Collaborative Group of the Spanish Society of Clinical Pharmacology.
    European journal of clinical pharmacology, 1991, Volume: 40, Issue:6

    Topics: Adolescent; Adult; Aged; Colic; Diclofenac; Dipyrone; Double-Blind Method; Female; Humans; Injection

1991
A double-blind single dose comparison of intramuscular ketorolac tromethamine and pethidine in the treatment of renal colic.
    Journal of clinical pharmacology, 1990, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Aged; Colic; Double-Blind Method; Drug Administration Schedule; Female; Humans; I

1990
Rectal diclofenac compared with pethidine injection in acute renal colic.
    BMJ (Clinical research ed.), 1989, Nov-04, Volume: 299, Issue:6708

    Topics: Administration, Rectal; Adult; Colic; Diclofenac; Drug Evaluation; Female; Humans; Injections; Kidne

1989
Analgesic effect and tolerance of Voltaren and Ketogan in acute renal or ureteric colic.
    British journal of urology, 1989, Volume: 63, Issue:1

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Allylamine; Amines; Analgesics; Clinical Trials as To

1989
Diclofenac sodium versus pethidine in acute renal colic.
    British medical journal (Clinical research ed.), 1986, Jan-25, Volume: 292, Issue:6515

    Topics: Acute Disease; Adult; Aged; Colic; Diclofenac; Double-Blind Method; Female; Humans; Kidney Diseases;

1986
Urological applications of butorphanol tartrate: postoperative pain and renal colic.
    Acute care, 1988, Volume: 12 Suppl 1

    Topics: Adolescent; Adult; Aged; Butorphanol; Colic; Double-Blind Method; Female; Humans; Kidney Diseases; M

1988
Comparison of butorphanol tartrate and meperidine in moderate to severe renal colic.
    Urology, 1987, Volume: 29, Issue:3

    Topics: Butorphanol; Clinical Trials as Topic; Colic; Double-Blind Method; Drug Tolerance; Humans; Kidney Di

1987

Other Studies

6 other studies available for meperidine and Kidney Diseases

ArticleYear
[Severe hyponatremia as the initial manifestation of hypopituitarism].
    Anales de medicina interna (Madrid, Spain : 1984), 2002, Volume: 19, Issue:6

    Topics: Adrenal Insufficiency; Analgesics, Opioid; Colic; Confusion; Disease Progression; Empty Sella Syndro

2002
Cause of death in narcotic intoxication in recent years.
    Danish medical bulletin, 1963, Volume: 10

    Topics: Cause of Death; Chlorprothixene; Heart Diseases; Humans; Imipramine; Kidney Diseases; Lung Diseases;

1963
[Guidelines of U.S. specialty societies on kidney stones: ureteroscopy and ESWL recommended as equivalent].
    Aktuelle Urologie, 2004, Volume: 35, Issue:5

    Topics: Algorithms; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Colic; Cyclooxygenase Inhib

2004
Supra-malleolar acupuncture substituting for pethidine in appeasement of renal colic.
    Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 1988, Volume: 8, Issue:4

    Topics: Acupuncture Therapy; Adult; Ankle; Colic; Female; Humans; Kidney Diseases; Male; Meperidine; Middle

1988
Pharmacokinetics of low-dose intravenous pethidine in patients with renal dysfunction.
    Journal of clinical pharmacology, 1987, Volume: 27, Issue:7

    Topics: Adult; Blood Proteins; Female; Humans; Injections, Intravenous; Kidney Diseases; Male; Meperidine; M

1987
Adverse effects with acyclovir and meperidine.
    Annals of internal medicine, 1985, Volume: 103, Issue:6 ( Pt 1)

    Topics: Acyclovir; Drug Interactions; Humans; Kidney Diseases; Male; Meperidine; Middle Aged; Nervous System

1985