Page last updated: 2024-10-30

meperidine and Hypothermia

meperidine has been researched along with Hypothermia in 18 studies

Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.

Hypothermia: Lower than normal body temperature, especially in warm-blooded animals.

Research Excerpts

ExcerptRelevanceReference
" The secondary outcomes were the incidence of hypothermia, sedation, the use of meperidine to control shivering and complications."5.30Comparative study between intrathecal dexmedetomidine and intrathecal magnesium sulfate for the prevention of post-spinal anaesthesia shivering in uroscopic surgery; (RCT). ( Abdelhamid, BM; Aboella, WA; Elshall, A; Hassan, A; Hassan, MM; Hassan, P; Hossam Eldin, M; Khaled, D; Mostafa, M; Omar, H; Tawadros, PZ; Wedad, M, 2019)
"Novamin infusion can stop postoperative shivering and alleviates hypothermia and improves thermal comfort more effectively than tramadol and pethidine with less nausea and vomiting and causes a clinically acceptable blood glucose increase with no reshivering episodes."5.19Novamin infusion: a new method to cure postoperative shivering with hypothermia. ( Ge, S; Wang, T; Wang, Y; Xiong, W; Xue, Z; Zhou, P, 2014)
"The effects of morphine and pethidine upon body temperature and upon the reversal of reserpine hypothermia in the mouse were investigated."3.65A comparison of the effects of morphine and pethidine upon body temperature and the reversal of reserpine's effects upon body temperature in the mouse. ( Menon, AM; Pleuvry, BJ, 1976)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19909 (50.00)18.7374
1990's6 (33.33)18.2507
2000's0 (0.00)29.6817
2010's3 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Omar, H1
Aboella, WA1
Hassan, MM1
Hassan, A1
Hassan, P1
Elshall, A1
Khaled, D1
Mostafa, M1
Tawadros, PZ1
Hossam Eldin, M1
Wedad, M1
Abdelhamid, BM1
Zhou, P1
Ge, S1
Wang, Y1
Xiong, W1
Wang, T1
Xue, Z1
Luggya, TS1
Kabuye, RN1
Mijumbi, C1
Tindimwebwa, JB1
Kintu, A1
L'ALLEMAND, H1
BRENDEL, W1
PETERSEN, H1
BLOCH, M1
HEYATE, D1
DUNDEE, JW1
CLARKE, RS1
Matsukawa, T1
Sessler, DI1
Christensen, R1
Ozaki, M1
Schroeder, M1
Rosa, G1
Pinto, G1
Orsi, P1
de Blasi, RA1
Conti, G1
Sanitá, R1
La Rosa, I1
Gasparetto, A1
Crossley, AW1
Ward, J1
Tighe, KE1
Giesbrecht, GG1
Goheen, MS1
Johnston, CE1
Kenny, GP1
Bristow, GK1
Hayward, JS1
Smith, CE1
Desai, R1
Glorioso, V1
Cooper, A1
Pinchak, AC1
Hagen, KF1
Menon, AM1
Pleuvry, BJ1
Oldfield, EC1
Ahtee, L1
Jounela, AJ1
Saarnivaara, L1
Simola, I1
Tischler, E1
Ylöstalo, P1
Kauppila, E1
Vapaatalo, H1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of Ambient Temperature and Forced-air Warming on Intraoperative Core Temperature[NCT02715076]292 participants (Actual)Interventional2016-01-31Completed
Effects of Preanesthetic Forced Air Warming and Administration of Warmed Intravascular Fluid on Preventing Hypothermia and Shivering During Cesarean Delivery Under Spinal Anesthesia[NCT03256786]50 participants (Actual)Observational2017-07-12Completed
A Prospective Randomized Evaluation of Two Perioperative Active Warming Techniques in Maintenance of Normothermia in Colorectal Surgeries[NCT00913978]50 participants (Actual)Interventional2017-04-13Terminated (stopped due to Study terminated due to financial status of sponsor.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Rate of Core Temperature Change

Rate of core temperature change from 1 to 3 hours after induction of anesthesia (°C/hour ) linear mixed-effects model to assess the effects of ambient temperature, forced-air warming and their interaction on the rate of core temperature change during 1 to 3h after induction (NCT02715076)
Timeframe: from 1 to 3 hours after induction of anesthesia

Interventiondegree C (Mean)
Ambient Temp 19°C & Passive Insulation-0.18
Ambient Temp 19°C & Forced-air Warming0.05
Ambient Temp 21°C & Passive Insulation-0.06
Ambient Temp 21°C & Forced-air Warming0.07
Ambient Temp 23°C & Passive Insulation-0.05
Ambient Temp 23°C & Forced-air Warming0.02

Post Operative Temperature on Admission to Post Operative Care Unit (PACU)

Oral temperature in degrees celcius immediately after admission to the PACU after the planned surgical procedure has been completed. (NCT00913978)
Timeframe: Immediately after surgery

InterventionDegrees Celcius (Mean)
Group 1: VitaHeat36.6
Group 2: Bair Hugger36.8

The Primary Outcome Measure Will be the Percentage of Intraoperative Time the Participants Body Temperature is Above 36 Degrees Celcius.

The total percent of intraoperative time (time in the operating room) that the body temperature of the participant is above 36 degrees celcius measured using an esophageal temperature probe. (NCT00913978)
Timeframe: 1 day

Interventionpercent time (Mean)
Group 1: VitaHeat47.1
Group 2: Bair Hugger72.0

Trials

6 trials available for meperidine and Hypothermia

ArticleYear
Comparative study between intrathecal dexmedetomidine and intrathecal magnesium sulfate for the prevention of post-spinal anaesthesia shivering in uroscopic surgery; (RCT).
    BMC anesthesiology, 2019, 10-24, Volume: 19, Issue:1

    Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Anesthesia, Spinal; Anesthetics; Anesthetics, Local; Bu

2019
Novamin infusion: a new method to cure postoperative shivering with hypothermia.
    The Journal of surgical research, 2014, May-01, Volume: 188, Issue:1

    Topics: Adult; Amino Acids; Analgesics, Opioid; Electrolytes; Female; Glucose; Humans; Hypothermia; Male; Me

2014
Heat flow and distribution during epidural anesthesia.
    Anesthesiology, 1995, Volume: 83, Issue:5

    Topics: Adjuvants, Anesthesia; Anesthesia, Epidural; Anesthetics, Local; Body Temperature Regulation; Humans

1995
Heat flow and distribution during epidural anesthesia.
    Anesthesiology, 1995, Volume: 83, Issue:5

    Topics: Adjuvants, Anesthesia; Anesthesia, Epidural; Anesthetics, Local; Body Temperature Regulation; Humans

1995
Heat flow and distribution during epidural anesthesia.
    Anesthesiology, 1995, Volume: 83, Issue:5

    Topics: Adjuvants, Anesthesia; Anesthesia, Epidural; Anesthetics, Local; Body Temperature Regulation; Humans

1995
Heat flow and distribution during epidural anesthesia.
    Anesthesiology, 1995, Volume: 83, Issue:5

    Topics: Adjuvants, Anesthesia; Anesthesia, Epidural; Anesthetics, Local; Body Temperature Regulation; Humans

1995
Control of post anaesthetic shivering with nefopam hydrochloride in mildly hypothermic patients after neurosurgery.
    Acta anaesthesiologica Scandinavica, 1995, Volume: 39, Issue:1

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Basal Metabolism; Blood Pressure; Body T

1995
Inhibition of shivering increases core temperature afterdrop and attenuates rewarming in hypothermic humans.
    Journal of applied physiology (Bethesda, Md. : 1985), 1997, Volume: 83, Issue:5

    Topics: Adult; Analgesics, Opioid; Blood Gas Analysis; Body Temperature; Female; Heart Rate; Humans; Hypothe

1997
Preventing hypothermia: convective and intravenous fluid warming versus convective warming alone.
    Journal of clinical anesthesia, 1998, Volume: 10, Issue:5

    Topics: Adult; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalati

1998

Other Studies

12 other studies available for meperidine and Hypothermia

ArticleYear
Prevalence, associated factors and treatment of post spinal shivering in a Sub-Saharan tertiary hospital: a prospective observational study.
    BMC anesthesiology, 2016, 10-18, Volume: 16, Issue:1

    Topics: Adjuvants, Anesthesia; Adult; Africa South of the Sahara; Anesthesia, Obstetrical; Anesthesia, Spina

2016
[Mechanism of controlled hypothermia].
    Langenbecks Archiv fur klinische Chirurgie ... vereinigt mit Deutsche Zeitschrift fur Chirurgie, 1954, Volume: 279

    Topics: Antipsychotic Agents; Body Temperature; Chlorpromazine; Hypothermia; Meperidine; Phenothiazines

1954
[Hyperpyrexia & poor general condition treated with hypothermia].
    Nordisk medicin, 1958, Jan-16, Volume: 59, Issue:3

    Topics: Chlorpromazine; Humans; Hyperthermia, Induced; Hypothermia; Hypothermia, Induced; Meperidine

1958
SOME SYSTEMIC EFFECTS OF NITROUS OXIDE.
    British journal of anaesthesia, 1963, Volume: 35

    Topics: Anesthesia; Anesthesia, General; Anesthetics; Blood Pressure; Blood Pressure Determination; Chlorpro

1963
OPEN HEART SURGERY IN IRAN.
    The Journal of the International College of Surgeons, 1964, Volume: 41

    Topics: Adolescent; Cardiac Surgical Procedures; Curare; Humans; Hypothermia; Hypothermia, Induced; Iran; Me

1964
PHARMACOLOGY OF HYPOTHERMIA.
    International anesthesiology clinics, 1964, Volume: 2

    Topics: Acetylcholine; Acid-Base Equilibrium; Anesthetics; Anti-Bacterial Agents; Carbohydrate Metabolism; C

1964
The treatment of postoperative shivering.
    Anaesthesia, 1995, Volume: 50, Issue:11

    Topics: Adjuvants, Anesthesia; Humans; Hypothermia; Meperidine; Postoperative Complications; Shivering

1995
A comparison of the effects of morphine and pethidine upon body temperature and the reversal of reserpine's effects upon body temperature in the mouse.
    The Journal of pharmacy and pharmacology, 1976, Volume: 28, Issue:11

    Topics: Adrenalectomy; Animals; Body Temperature; Dose-Response Relationship, Drug; Female; Hypothermia; Mal

1976
Meperidine for prevention of amphotericin B-induced chills.
    Clinical pharmacy, 1990, Volume: 9, Issue:4

    Topics: Adult; Amphotericin B; Humans; Hypothermia; Male; Meperidine

1990
Interactions of some analgesics and antidepressants with phenelzine or reserpine in the mouse.
    Pharmacology, 1974, Volume: 12, Issue:1

    Topics: Alphaprodine; Analgesics; Animals; Antidepressive Agents; Body Temperature; Drug Interactions; Fencl

1974
Intravenous chlormethiazole in the management of severe pre-eclampsia.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1973, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Apgar Score; Chlormethiazole; Chlo

1973
Complications following the intra-amniotic administration of prostaglandin f-2-alpha for therapeutic abortion.
    Acta obstetricia et gynecologica Scandinavica, 1974, Volume: 53, Issue:3

    Topics: Abortion, Induced; Adult; Bradycardia; Cervix Uteri; Female; Heart Rate; Humans; Hypotension; Hypoth

1974