Page last updated: 2024-10-30

meperidine and Hypotension

meperidine has been researched along with Hypotension in 49 studies

Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.

Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.

Research Excerpts

ExcerptRelevanceReference
"A sixty-eight-year-old female developed severe hypotension immediately after the administration of epidural meperidine for post-thoracotomy pain."7.67Severe hypotension from epidural meperidine in a high-risk patient after thoracotomy. ( Balaban, M; Slinger, P, 1989)
"The most important symptom in acute pancreatitis is pain."6.41[Meperidine (pethidine) outdated as analgesic in acute pancreatitis]. ( Helmers, JH; Otten, MH; Tjoeng, MM; van Voorthuizen, T, 2000)
"One hundred and twenty-eight term nulliparous women with singleton pregnancy and vertex presentation were randomized to receive either epidural (n=43), meperidine (n=39) or tramadol (n=44)."5.10Analgesic efficacy of intramuscular opioids versus epidural analgesia in labor. ( Arya, VK; Gopalan, S; Jain, S; Jain, V, 2003)
" The incidence of bradycardia was higher in the groups receiving meperidine."5.09Adding low dose meperidine to spinal lidocaine prolongs postoperative analgesia. ( Cicutti, N; Lui, AC; Murto, K, 1999)
"We aimed to determine the usefulness of intrathecal pethidine as the sole anaesthetic for transurethral resection of prostate (TURP) while comparing the incidence of hypotension with intrathecal bupivacaine."5.08Intrathecal pethidine: an alternative anaesthetic for transurethral resection of prostate? ( Chong, JL; Chow, MY; Koay, CK; Sia, AT, 1997)
" The following 4 cardiopulmonary complications were assessed: hypoxia, hypotension, arrhythmias, and apnea."4.82Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis. ( Khandwala, F; Lopez, R; Qadeer, MA; Vargo, JJ; Zuccaro, G, 2005)
"A sixty-eight-year-old female developed severe hypotension immediately after the administration of epidural meperidine for post-thoracotomy pain."3.67Severe hypotension from epidural meperidine in a high-risk patient after thoracotomy. ( Balaban, M; Slinger, P, 1989)
"Hypotension was documented in two patients in the propofol group and one patient receiving midazolam/meperidine."2.71Sedation with propofol for routine ERCP in high-risk octogenarians: a randomized, controlled study. ( Riphaus, A; Stergiou, N; Wehrmann, T, 2005)
"The incidences of arrhythmias, lung oedema, hypotension and thromboembolic complications did not differ between the groups."2.65Analgesic treatment with levomepromazine in acute myocardial infarction. A randomized clinical trial. ( Davidsen, O; Lindeneg, O; Walsh, M, 1979)
"The most important symptom in acute pancreatitis is pain."2.41[Meperidine (pethidine) outdated as analgesic in acute pancreatitis]. ( Helmers, JH; Otten, MH; Tjoeng, MM; van Voorthuizen, T, 2000)
"The use of opioids for postoperative pain control is common after spinal surgery; however, PONV is the most frequently encountered side effect, and it is yet to be overcome."1.37A comparison of three types of postoperative pain control after posterior lumbar spinal surgery. ( Chen, LH; Chen, WJ; Niu, CC; Tsai, TT; Wong, CH; Wu, MH, 2011)
"Pain was the most common complication, although use of analgesia after 2 hours of observation was low."1.35Post-procedure surveillance in liver biopsy: how long is long enough? ( Basford, P; Bell, M; Derrett, S; Howard, R; Karageorge, G; Schultz, M; van Harselaar, K, 2008)
" Deep sedation was induced in 260 patients using midazolam, phenergan, and meperidine, then maintained with intermittent dosing of meperidine at the following mean doses: midazolam 0."1.30Evaluation of the safety and efficacy of deep sedation for electrophysiology procedures administered in the absence of an anesthetist. ( Brandon, MJ; Geiger, MJ; Kearney, MM; Kent, V; Natale, A; Newby, KH; Wase, A, 1997)
" The pharmacokinetic data suggests that intrathecal meperidine provides prolonged postoperative analgesia through a regional effect on opioid receptors in the spinal cord."1.27Pharmacokinetics of meperidine in spinal anaesthesia. ( Absood, A; Famewo, CE; Naguib, M, 1986)
"1."1.26[Anesthesia in pacemaker implantation. Experiences in 935 cases of anesthesia for the implantation or revision of a cardiac pacemaker]. ( Blaum, U; Pflüger, H; Schmidt, H, 1977)

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-199029 (59.18)18.7374
1990's9 (18.37)18.2507
2000's8 (16.33)29.6817
2010's2 (4.08)24.3611
2020's1 (2.04)2.80

Authors

AuthorsStudies
Babaoğlu, G1
Kiliçaslan, B1
Ankay Yilbaş, A1
Çelebioğlu, B1
Luggya, TS1
Kabuye, RN1
Mijumbi, C1
Tindimwebwa, JB1
Kintu, A1
Howard, R1
Karageorge, G1
van Harselaar, K1
Bell, M1
Basford, P1
Schultz, M1
Derrett, S1
Wu, MH1
Wong, CH1
Niu, CC1
Tsai, TT1
Chen, LH1
Chen, WJ1
Lee, DW1
Chan, AC1
Sze, TS1
Ko, CW1
Poon, CM1
Chan, KC1
Sin, KS1
Chung, SC1
ZEPPA, R1
DUNDEE, JW4
VIGRAN, IM1
MARKELLO, R1
KING, BD1
HAGELSTEN, JO1
SOULAYROL, R1
LOB, H1
POINSO, Y1
BIENIARZ, J2
FERNANDEZ SEPULVEDA, R2
CALDEYRO BARCIA, R2
Jain, S1
Arya, VK1
Gopalan, S1
Jain, V1
Riphaus, A1
Stergiou, N1
Wehrmann, T1
Qadeer, MA1
Vargo, JJ1
Khandwala, F1
Lopez, R1
Zuccaro, G1
Kafle, SK1
Ngan Kee, WD1
Khor, KE1
Critchley, LA1
Morley, AP1
Smith, AJ1
Haynes, TK1
Roberts, DE1
Harmer, M1
St-Onge, S1
Fugère, F1
Girard, M1
Geiger, MJ1
Wase, A1
Kearney, MM1
Brandon, MJ1
Kent, V1
Newby, KH1
Natale, A1
Sia, AT1
Chow, MY1
Koay, CK1
Chong, JL1
Murto, K1
Lui, AC1
Cicutti, N1
van Voorthuizen, T1
Helmers, JH1
Tjoeng, MM1
Otten, MH1
Capogna, G1
Ehikhametalor, KO1
Nelson, M1
Davidsen, O1
Lindeneg, O1
Walsh, M1
McDowell, AJ1
Whitlow, DR1
Blaum, U1
Schmidt, H1
Pflüger, H1
Gaylard, DG1
Carson, RJ1
Reynolds, F1
Balaban, M1
Slinger, P1
Naguib, M1
Famewo, CE1
Absood, A1
Foldes, FF1
Tunstall, ME1
Ogg, TW1
Nagashima, H1
Radnay, PA1
Yun, H1
Kuwabara, S1
Buchan, AS1
Bauld, HW1
Ylöstalo, P1
Kauppila, E1
Vapaatalo, H1
Corssen, G1
Keats, AS1
Strong, MJ1
Girgis, KZ1
Goldstein, A1
Munro, WD1
Bannister, AK1
Morrison, JD1
Loan, WB1
McDowell, SA1
Brown, SS1
Gershengorn, K1
Haft, JI1
Clarke, RS1
Carson, IW1
Arora, MV1
McCaughey, W1
Steele, PR1
Masheter, HC1
Haslett, WH1
Keilty, SR1
Pandit, SK1
Kobayashi, S1
Hasegawa, K1
Oshima, T1
Takagi, H1
Evans-Prosser, CD1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00848861]92 participants (Actual)Interventional2006-02-28Completed
Comparison of Ketamine-propofol Sedation Protocols With Fentanyl-propofol Administered by Endoscopist or Anesthesiologist at Colonoscopy[NCT03607110]120 participants (Actual)Observational2018-03-01Completed
Incidence of Sedation Related Complications With Propofol Alone Versus Propofol With Benzodiazepines and Opiates in a High Risk Group Undergoing Advanced Endoscopic Procedures: A Randomized Controlled Trial[NCT01315158]36 participants (Actual)Interventional2011-01-31Terminated (stopped due to - The research team is not able to obtain the necessary support to continue the study.)
[NCT02039453]160 participants (Anticipated)Interventional2013-09-30Recruiting
A Psychomotor Recuperation Study After Deep Sedation for Colonoscopy Between Target Controlled and Manual Titration of Propofol.[NCT02314559]Phase 4164 participants (Actual)Interventional2015-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants Who Experience Airway Maneuvers

In high risk patients (meeting at least of 1 of 3 criteria: ASA ≥ 3, BMI ≥ 30, those at risk for OSA) undergoing advanced endoscopy procedures, compare the number of participants who experience airway maneuvers (AMs) when sedated with propofol alone versus propofol in combination with benzodiazepines and opioids. (NCT01315158)
Timeframe: One day (during procedure)

Interventionparticipants (Number)
Propofol+Benzo/Opioids4
Propofol Alone4

Number of Participants Who Experience Other Sedation Related Complications

Compare the number of participants who experience other sedation related complications such as hypotension, hypoxemia and need for termination of the procedure between the two groups (NCT01315158)
Timeframe: One day (during procedure)

Interventionparticipants (Number)
Propofol+Benzo/Opioids0
Propofol Alone0

Number of Participants Who Experience Symptoms of Nausea and Vomiting Will be Compared Between the Two Groups

The number of participants who experience symptoms of nausea and vomiting in the two groups of patients will be recorded. This will be recorded during the follow-up phone call made 24-48 hours after the procedure. (NCT01315158)
Timeframe: 24-48 hours

Interventionparticipants (Number)
Propofol+Benzo/Opioids2
Propofol Alone1

Predictors of Sedation Related Complications as Measured by Early Procedure Termination for an Alternative Sedation Related Complication

(NCT01315158)
Timeframe: One year

Interventionincidences (Number)
Propofol+Benzo/Opioids0
Propofol Alone0

Predictors of Sedation Related Complications as Measured by Hypopnea/Apnea (Defined as Fewer Than 6 Breaths/Minute Based on Capnography)

(NCT01315158)
Timeframe: One year

Interventionincidences (Number)
Propofol+Benzo/Opioids0
Propofol Alone0

Predictors of Sedation Related Complications as Measured by the Incidences of Hypotension (Defined as Systolic Blood Pressure of Less Than 90mmHg or a Decrease of More Than 25% From Baseline)

(NCT01315158)
Timeframe: One year

Interventionincidences (Number)
Propofol+Benzo/Opioids0
Propofol Alone0

Predictors of Sedation Related Complications as Measured by the Number of Participants Who Experience Hypoxemia (Defined as a Pulse Oximetry <90% for Any Duration)

(NCT01315158)
Timeframe: One year

Interventionparticipants (Number)
Propofol+Benzo/Opioids0
Propofol Alone0

Reviews

4 reviews available for meperidine and Hypotension

ArticleYear
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:11

    Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy

2005
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:11

    Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy

2005
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:11

    Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy

2005
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:11

    Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy

2005
[Meperidine (pethidine) outdated as analgesic in acute pancreatitis].
    Nederlands tijdschrift voor geneeskunde, 2000, Apr-01, Volume: 144, Issue:14

    Topics: Acute Disease; Analgesics, Opioid; Contraindications; Dyskinesia, Drug-Induced; Erythema; Humans; Hy

2000
Effect of epidural analgesia on the fetal heart rate.
    European journal of obstetrics, gynecology, and reproductive biology, 2001, Volume: 98, Issue:2

    Topics: Analgesics, Opioid; Anesthesia, Epidural; Clinical Trials as Topic; Female; Heart Rate, Fetal; Human

2001
Neuroleptanesthesia for general surgery.
    International anesthesiology clinics, 1973,Fall, Volume: 11, Issue:3

    Topics: Alphaprodine; Anesthesia, Inhalation; Diphenhydramine; Droperidol; Female; Fentanyl; Humans; Hyperte

1973

Trials

14 trials available for meperidine and Hypotension

ArticleYear
Patient-controlled sedation versus intravenous sedation for colonoscopy in elderly patients: a prospective randomized controlled trial.
    Gastrointestinal endoscopy, 2002, Volume: 56, Issue:5

    Topics: Aged; Alfentanil; Analgesia, Patient-Controlled; Anesthetics, Intravenous; Colonoscopy; Conscious Se

2002
Patient-controlled sedation versus intravenous sedation for colonoscopy in elderly patients: a prospective randomized controlled trial.
    Gastrointestinal endoscopy, 2002, Volume: 56, Issue:5

    Topics: Aged; Alfentanil; Analgesia, Patient-Controlled; Anesthetics, Intravenous; Colonoscopy; Conscious Se

2002
Patient-controlled sedation versus intravenous sedation for colonoscopy in elderly patients: a prospective randomized controlled trial.
    Gastrointestinal endoscopy, 2002, Volume: 56, Issue:5

    Topics: Aged; Alfentanil; Analgesia, Patient-Controlled; Anesthetics, Intravenous; Colonoscopy; Conscious Se

2002
Patient-controlled sedation versus intravenous sedation for colonoscopy in elderly patients: a prospective randomized controlled trial.
    Gastrointestinal endoscopy, 2002, Volume: 56, Issue:5

    Topics: Aged; Alfentanil; Analgesia, Patient-Controlled; Anesthetics, Intravenous; Colonoscopy; Conscious Se

2002
Analgesic efficacy of intramuscular opioids versus epidural analgesia in labor.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2003, Volume: 83, Issue:1

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Hu

2003
Sedation with propofol for routine ERCP in high-risk octogenarians: a randomized, controlled study.
    The American journal of gastroenterology, 2005, Volume: 100, Issue:9

    Topics: Aged; Cholangiopancreatography, Endoscopic Retrograde; Comorbidity; Conscious Sedation; Feasibility

2005
Sedation with propofol for routine ERCP in high-risk octogenarians: a randomized, controlled study.
    The American journal of gastroenterology, 2005, Volume: 100, Issue:9

    Topics: Aged; Cholangiopancreatography, Endoscopic Retrograde; Comorbidity; Conscious Sedation; Feasibility

2005
Sedation with propofol for routine ERCP in high-risk octogenarians: a randomized, controlled study.
    The American journal of gastroenterology, 2005, Volume: 100, Issue:9

    Topics: Aged; Cholangiopancreatography, Endoscopic Retrograde; Comorbidity; Conscious Sedation; Feasibility

2005
Sedation with propofol for routine ERCP in high-risk octogenarians: a randomized, controlled study.
    The American journal of gastroenterology, 2005, Volume: 100, Issue:9

    Topics: Aged; Cholangiopancreatography, Endoscopic Retrograde; Comorbidity; Conscious Sedation; Feasibility

2005
Intrathecal meperidine for elective caesarean section: a comparison with lidocaine.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:8

    Topics: Adult; Analgesia, Obstetrical; Anesthesia, Epidural; Apgar Score; Cesarean Section; Female; Humans;

1993
A comparison of opioid solutions for patient-controlled epidural analgesia.
    Anaesthesia, 1996, Volume: 51, Issue:11

    Topics: Aged; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Bupivacaine; Double-Bl

1996
Bupivacaine decreases epidural meperidine requirements after abdominal surgery.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:4

    Topics: Abdomen; Analgesia, Epidural; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bupivacai

1997
Intrathecal pethidine: an alternative anaesthetic for transurethral resection of prostate?
    Anaesthesia and intensive care, 1997, Volume: 25, Issue:6

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Do

1997
Adding low dose meperidine to spinal lidocaine prolongs postoperative analgesia.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1999, Volume: 46, Issue:4

    Topics: Adjuvants, Anesthesia; Aged; Aged, 80 and over; Analgesia; Analgesics, Opioid; Analysis of Variance;

1999
Intrathecal pethidine as sole anaesthetic agent for operative procedures of the lower limb, inguinal area and perineum.
    The West Indian medical journal, 2001, Volume: 50, Issue:4

    Topics: Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Lo

2001
Analgesic treatment with levomepromazine in acute myocardial infarction. A randomized clinical trial.
    Acta medica Scandinavica, 1979, Volume: 205, Issue:3

    Topics: Acute Disease; Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Double-Blind Method; Drug Evalu

1979
Piritramide and pethidine. A comparison of their use as supplements in general anaesthesia.
    Anaesthesia, 1974, Volume: 29, Issue:6

    Topics: Anesthesia, General; Female; Humans; Hypotension; Isonipecotic Acids; Meperidine; Nitriles; Pain, Po

1974
Neuroleptanesthesia with morphine for aortocoronary bypass surgery.
    Der Anaesthesist, 1974, Volume: 23, Issue:8

    Topics: Adult; Aged; Blood Pressure; Coronary Artery Bypass; Droperidol; Drug Synergism; Female; Fentanyl; H

1974
Studies of drugs given before anaesthesia. 18. The synthetic opiates.
    British journal of anaesthesia, 1969, Volume: 41, Issue:11

    Topics: Analgesics; Clinical Trials as Topic; Dextromoramide; Female; Fentanyl; Humans; Hypotension; Levorph

1969
Phenoperidine and droperidol as premedicants. A controlled study in ophthalmic surgical procedures in combination with retrobulbar block.
    Anaesthesia, 1971, Volume: 26, Issue:3

    Topics: Aged; Amnesia; Analgesics; Benperidol; Female; Humans; Hypotension; Injections, Intramuscular; Injec

1971

Other Studies

31 other studies available for meperidine and Hypotension

ArticleYear
Effects of different analgesic methods used for vaginal delivery on mothers and fetuses
    Turkish journal of medical sciences, 2020, 06-23, Volume: 50, Issue:4

    Topics: Adult; Analgesia; Analgesics, Opioid; Anesthesia, Spinal; Apgar Score; Case-Control Studies; Cesarea

2020
Prevalence, associated factors and treatment of post spinal shivering in a Sub-Saharan tertiary hospital: a prospective observational study.
    BMC anesthesiology, 2016, 10-18, Volume: 16, Issue:1

    Topics: Adjuvants, Anesthesia; Adult; Africa South of the Sahara; Anesthesia, Obstetrical; Anesthesia, Spina

2016
Post-procedure surveillance in liver biopsy: how long is long enough?
    The New Zealand medical journal, 2008, Aug-22, Volume: 121, Issue:1280

    Topics: Adult; Aged; Analgesics, Opioid; Biopsy; Central Nervous System Depressants; Continuity of Patient C

2008
A comparison of three types of postoperative pain control after posterior lumbar spinal surgery.
    Spine, 2011, Dec-01, Volume: 36, Issue:25

    Topics: Aged; Analgesia; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Decompressi

2011
HYPOTENSION of narcotic withdrawal.
    New York state journal of medicine, 1958, Oct-15, Volume: 58, Issue:20

    Topics: Behavior, Addictive; Humans; Hypotension; Medical Records; Meperidine; Narcotics; Substance Withdraw

1958
Role of histamine in meperidine-induced hypotension.
    The Journal of surgical research, 1962, Volume: 2

    Topics: Histamine; Hypotension; Meperidine

1962
CLINICAL STUDIES OF INDUCTION AGENTS. VII: A COMPARISON OF EIGHT INTRAVENOUS ANAESTHETICS AS MAIN AGENTS FOR A STANDARD OPERATION.
    British journal of anaesthesia, 1963, Volume: 35

    Topics: Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; Atropine; Barbiturates; Hexobarbital;

1963
DANGEROUS POTENTIATION OF MEPERIDINE HYDROCHLORIDE BY PARGYLINE HYDROCHLORIDE.
    JAMA, 1964, Mar-21, Volume: 187

    Topics: Antihypertensive Agents; Hypotension; Hypotension, Orthostatic; Meperidine; Monoamine Oxidase Inhibi

1964
PRACTICALITY OF HALOTHANE-AIR ANESTHESIA.
    New York state journal of medicine, 1964, Sep-01, Volume: 64

    Topics: Acidosis; Anesthesia; Anesthesia, Inhalation; Biomedical Research; Blood Gas Analysis; Equipment and

1964
FLUOTHANE-ETHER AZEOTROPIC MIXTURE.
    Danish medical bulletin, 1964, Volume: 11

    Topics: Chlorpromazine; Curare; Ether; Ethers; Geriatrics; Halothane; Humans; Hypotension; Meperidine; Morph

1964
[INCIDENTS DUE TO DRUG INTERFERENCE WITH MONOAMINE OXIDASE INHIBITORS].
    Revue de neuropsychiatrie infantile et d'hygiene mentale de l'enfance, 1964, Volume: 12

    Topics: Amphetamine; Amphetamines; Coma; Hypotension; Imipramine; Meperidine; Monoamine Oxidase Inhibitors;

1964
EFFECTS OF MATERNAL HYPOTENSION ON THE HUMAN FETUS. I. FETAL HEART RATE DURING NORMAL LABOR.
    American journal of obstetrics and gynecology, 1965, Jul-15, Volume: 92

    Topics: Anesthesia; Anesthesia, Obstetrical; Chlorpromazine; Female; Fetal Heart; Fetus; Heart Rate, Fetal;

1965
EFFECTS OF MATERNAL HYPOTENSION ON THE HUMAN FETUS. II. FETAL HEART RATE IN LABORS ASSOCIATED WITH CORD AROUND THE NECK AND TOXEMIA.
    American journal of obstetrics and gynecology, 1965, Jul-15, Volume: 92

    Topics: Anesthesia; Anesthesia, Obstetrical; Chlorpromazine; Female; Fetal Heart; Heart Rate, Fetal; Humans;

1965
Intrathecal pethidine: a word of caution.
    Anaesthesia, 1993, Volume: 48, Issue:3

    Topics: Anesthesia, Spinal; Humans; Hypotension; Meperidine

1993
Complications of intrathecal administration of pethidine.
    Anaesthesia, 1996, Volume: 51, Issue:7

    Topics: Analgesics, Opioid; Bradycardia; Humans; Hypotension; Injections, Spinal; Meperidine

1996
Evaluation of the safety and efficacy of deep sedation for electrophysiology procedures administered in the absence of an anesthetist.
    Pacing and clinical electrophysiology : PACE, 1997, Volume: 20, Issue:7

    Topics: Adjuvants, Anesthesia; Airway Obstruction; Anesthesia, Intravenous; Anesthesiology; Anesthetics, Int

1997
Reversible, titrated deep sedation for major office surgery.
    Plastic and reconstructive surgery, 1977, Volume: 59, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthesia, Local; Arrhythmias, Cardiac; Bradycardia; Humans; Hypotension;

1977
[Anesthesia in pacemaker implantation. Experiences in 935 cases of anesthesia for the implantation or revision of a cardiac pacemaker].
    Fortschritte der Medizin, 1977, May-12, Volume: 95, Issue:18

    Topics: Anesthesia, General; Arrhythmia, Sinus; Bradycardia; Halothane; Heart Arrest; Heart Block; Humans; H

1977
Effect of umbilical perfusate pH and controlled maternal hypotension on placental drug transfer in the rabbit.
    Anesthesia and analgesia, 1990, Volume: 71, Issue:1

    Topics: Anesthesia, Obstetrical; Animals; Antipyrine; Bupivacaine; Chromatography, Gas; Female; Hydrogen-Ion

1990
Severe hypotension from epidural meperidine in a high-risk patient after thoracotomy.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1989, Volume: 36, Issue:4

    Topics: Aged; Analgesia, Epidural; Female; Humans; Hypotension; Meperidine; Pain, Postoperative; Thoracotomy

1989
Pharmacokinetics of meperidine in spinal anaesthesia.
    Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:2

    Topics: Adult; Anesthesia, Spinal; Bradycardia; Half-Life; Hemorrhoids; Humans; Hypotension; Kinetics; Male;

1986
Blood-gas changes during trichloroethylene and intravenous pethidine anaesthesia.
    British journal of anaesthesia, 1973, Volume: 45, Issue:1

    Topics: Aged; Anesthesia, General; Bicarbonates; Blood Pressure; Carbon Dioxide; Female; Heart Rate; Hematoc

1973
Complications following the intra-amniotic administration of prostaglandin f-2-alpha for therapeutic abortion.
    Acta obstetricia et gynecologica Scandinavica, 1974, Volume: 53, Issue:3

    Topics: Abortion, Induced; Adult; Bradycardia; Cervix Uteri; Female; Heart Rate; Humans; Hypotension; Hypoth

1974
Neuroleptanalgesia and anesthesia in obstetrics.
    Clinical obstetrics and gynecology, 1974, Volume: 17, Issue:2

    Topics: Anesthesia, Inhalation; Anesthesia, Obstetrical; Droperidol; Drug Combinations; Drug Synergism; Eval

1974
Observations during anesthesia for cardiac homotransplantation in ten patients.
    Anesthesiology, 1969, Volume: 30, Issue:2

    Topics: Adolescent; Adult; Anesthesia, Inhalation; Atropine; Blood Pressure; Bradycardia; Calcium Chloride;

1969
Phenoperidine in anaesthesia of respiratory cripples.
    Acta anaesthesiologica Scandinavica. Supplementum, 1966, Volume: 23

    Topics: Abdomen; Adjuvants, Anesthesia; Analgesics; Anesthesia, General; Blood Pressure; Chlorpromazine; Cur

1966
Intermittent heart block related to treatment of hypertension in a patient with acute myocardial infarction.
    Chest, 1972, Volume: 61, Issue:4

    Topics: Antihypertensive Agents; Blood Pressure Determination; Electrocardiography; Heart Block; Heart Condu

1972
Clinical studies of induction agents. XL. Althesin with various premedicants.
    British journal of anaesthesia, 1972, Volume: 44, Issue:8

    Topics: Anesthesia, Intravenous; Anesthetics; Atropine; Diazepam; Female; Humans; Hypotension; Ketones; Mepe

1972
Studies of drugs given before anaesthesia. XX. Diazepam-containing mixtures.
    British journal of anaesthesia, 1970, Volume: 42, Issue:2

    Topics: Adult; Blood Pressure; Diazepam; Drug Synergism; Humans; Hypotension; Injections, Intramuscular; Inj

1970
The pharmacology of azabicyclane, a new analgesic agent.
    Toxicology and applied pharmacology, 1970, Volume: 17, Issue:2

    Topics: Analgesics; Animals; Antitussive Agents; Body Weight; Cardiovascular System; Constriction; Digestive

1970
The use of pethidine and morphine in the presence of monoamine oxidase inhibitors.
    British journal of anaesthesia, 1968, Volume: 40, Issue:4

    Topics: Adult; Blood Pressure; Drug Hypersensitivity; Drug Synergism; Female; Heart Rate; Humans; Hypertensi

1968