Page last updated: 2024-10-30

meperidine and Hyperventilation

meperidine has been researched along with Hyperventilation in 7 studies

Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.

Hyperventilation: A pulmonary ventilation rate faster than is metabolically necessary for the exchange of gases. It is the result of an increased frequency of breathing, an increased tidal volume, or a combination of both. It causes an excess intake of oxygen and the blowing off of carbon dioxide.

Research Excerpts

ExcerptRelevanceReference
"Secondary changes consist of polycythemia, somnolence, headache and right heart failure."1.24HYPOVENTILATION, CYANOSIS AND POLYCYTHEMIA IN A THIN MAN. ( DVORKIN, J; FRASER, RS; SPROULE, BJ, 1963)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19907 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
FRASER, RS1
SPROULE, BJ1
DVORKIN, J1
Rooth, G1
Hoppe, E1
Christensen, L1
Christensen, KN1
Cullen, BF1
Margolis, AJ1
Eger, EI1
Steel, GC1
Bonica, JJ1
Rosen, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Sevoflurane as an Anesthetic During Dilation and Evacuation Procedures: Does it Increase Blood Loss and Interventions for Blood Loss and Why Do Anesthesiologists Choose to Use It?[NCT01048658]Phase 4160 participants (Actual)Interventional2009-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants Experiencing Side Effects (Nausea, Dizziness)

(NCT01048658)
Timeframe: Post-procedure, within 30 minutes

InterventionParticipants (Count of Participants)
Sevoflurane13
No Sevoflurane11

Number of Participants Needing Intervention to Treat Blood Loss (a Composite of Use of Uterotonics, Re-aspiration, and Bimanual Massage)

Provider report for need to intervene due to blood loss (yes/no) (NCT01048658)
Timeframe: At time of uterine evacuation and immediately post-operatively, an average of 7.1 minutes

InterventionParticipants (Count of Participants)
Sevoflurane20
No Sevoflurane13

Number of Participants With Estimated Blood Loss Greater Than 300 mL (Yes/no)

Procedural blood loss greater than 300 mL. Blood loss was measured in a standardized fashion (amniotic fluid was discarded, blood was separated from tissue, and all gauze surgical drapes weighed). (NCT01048658)
Timeframe: At time of uterine evacuation, an average of 7.1 minutes

InterventionParticipants (Count of Participants)
Sevoflurane12
No Sevoflurane6

Procedure Time: T-test (Time of Speculum Placement to Time Speculum Removed)

Length of procedure from time of speculum placement to time of speculum removal, in minutes. (NCT01048658)
Timeframe: Time of speculum place to time of speculum removal, an average of 7.1 minutes

Interventionminutes (Mean)
Sevoflurane7.0
No Sevoflurane7.3

Patient and Provider Satisfaction With Anesthesia

Scores reported on 10-cm Visual Analog Scale (VAS anchors: 0= not satisfied at all, 10= completely satisfied) . Reported as mean +/- standard deviation. Subjects and providers were blinded to anesthesia method. Subjects and providers completed post-operative questionnaire within 30 minutes of procedure completion. (NCT01048658)
Timeframe: Post-procedure, within 30 minutes

,
Interventioncm (Mean)
Provider SatisfactionPatient Satisfaction
No Sevoflurane9.38.2
Sevoflurane9.48.4

Reviews

3 reviews available for meperidine and Hyperventilation

ArticleYear
Obstetric analgesia.
    International anesthesiology clinics, 1973,Spring, Volume: 11, Issue:1

    Topics: Analgesics; Anesthesia, Epidural; Anesthesia, Inhalation; Anesthesia, Local; Anesthesia, Obstetrical

1973
Maternal respiratory changes during pregnancy and parturition.
    Clinical anesthesia, 1974, Volume: 10, Issue:2

    Topics: Airway Resistance; Anesthesia, Epidural; Carbon Dioxide; Elasticity; Female; Humans; Hyperventilatio

1974
Recent advances in pain relief in childbirth. I. Inhalation and systemic analgesia.
    British journal of anaesthesia, 1971, Volume: 43, Issue:9

    Topics: Analgesics; Anesthesia, Inhalation; Anesthesia, Obstetrical; Diazepam; Female; Humans; Hyperventilat

1971

Trials

1 trial available for meperidine and Hyperventilation

ArticleYear
The effects of anesthesia and pulmonary ventilation on blood loss during elective therapeutic abortion.
    Anesthesiology, 1970, Volume: 32, Issue:2

    Topics: Abortion, Therapeutic; Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthesia, Obstetric

1970

Other Studies

3 other studies available for meperidine and Hyperventilation

ArticleYear
HYPOVENTILATION, CYANOSIS AND POLYCYTHEMIA IN A THIN MAN.
    Canadian Medical Association journal, 1963, Dec-07, Volume: 89

    Topics: Cyanosis; Headache; Heart Failure; Humans; Hyperventilation; Hypoventilation; Male; Meperidine; Poly

1963
Maternal hypoxaemia during labor.
    Padiatrie und Padologie, 1982, Volume: 17, Issue:2

    Topics: Carbon Dioxide; Female; Humans; Hyperventilation; Hypoxia; Maternal-Fetal Exchange; Meperidine; Nitr

1982
The clinical outcome of patients with severe head injuries, treated with highdose dexamethasone, hyperventilation and barbiturates.
    Neurochirurgia, 1981, Volume: 24, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Brain Injuries; Child; Child, Preschool; Chlorpromazine; Dexam

1981