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meperidine and Epilepsy, Tonic-Clonic

meperidine has been researched along with Epilepsy, Tonic-Clonic in 6 studies

Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.

Epilepsy, Tonic-Clonic: A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)

Research Excerpts

ExcerptRelevanceReference
"To report three cases of meperidine-related seizures when meperidine was administered via patient-controlled analgesia pump (PCAP) and to review literature related to meperidine-associated seizures."8.78Meperidine-related seizures associated with patient-controlled analgesia pumps. ( Hagmeyer, KO; Mauro, LS; Mauro, VF, 1993)
"To report three cases of meperidine-related seizures when meperidine was administered via patient-controlled analgesia pump (PCAP) and to review literature related to meperidine-associated seizures."4.78Meperidine-related seizures associated with patient-controlled analgesia pumps. ( Hagmeyer, KO; Mauro, LS; Mauro, VF, 1993)
"Meperidine is a widely prescribed opioid analgesic used in a variety of clinical situations."1.30Meperidine-induced generalized seizures with normal renal function. ( Marinella, MA, 1997)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's3 (50.00)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hochman, MS1
Hagmeyer, KO1
Mauro, LS1
Mauro, VF1
Marinella, MA1
Emerson, GM1
Oxer, HF1
Hassan, H1
Bastani, B1
Gellens, M1
Knight, B1
Thomson, N1
Perry, G1

Reviews

1 review available for meperidine and Epilepsy, Tonic-Clonic

ArticleYear
Meperidine-related seizures associated with patient-controlled analgesia pumps.
    The Annals of pharmacotherapy, 1993, Volume: 27, Issue:1

    Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Epilepsy, Tonic-Clonic; Female; Humans; Ketorolac;

1993

Other Studies

5 other studies available for meperidine and Epilepsy, Tonic-Clonic

ArticleYear
Meperidine-associated myoclonus and seizures in long-term hemodialysis patients.
    Annals of neurology, 1983, Volume: 14, Issue:5

    Topics: Epilepsies, Myoclonic; Epilepsy, Tonic-Clonic; Female; Humans; Male; Meperidine; Middle Aged; Renal

1983
Meperidine-induced generalized seizures with normal renal function.
    Southern medical journal, 1997, Volume: 90, Issue:5

    Topics: Abdominal Pain; Adult; Analgesics, Opioid; Cholinesterase Inhibitors; Chronic Disease; Epilepsy, Ton

1997
Unusual causes of convulsions in a hyperbaric chamber.
    Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 1998,Summer, Volume: 25, Issue:2

    Topics: Adult; Analgesics, Opioid; Diving; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Female; Humans; Hy

1998
Successful treatment of normeperidine neurotoxicity by hemodialysis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2000, Volume: 35, Issue:1

    Topics: Aged; Analgesics, Opioid; Epilepsies, Myoclonic; Epilepsy, Tonic-Clonic; Female; Half-Life; Humans;

2000
Seizures due to norpethidine toxicity.
    Australian and New Zealand journal of medicine, 2000, Volume: 30, Issue:4

    Topics: Cholinesterase Inhibitors; Epilepsy, Tonic-Clonic; Female; Humans; Meperidine; Middle Aged

2000