meperidine has been researched along with Drug Withdrawal Symptoms in 38 studies
Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Rats were infused with morphine or meperidine for 24 or 48 h at constant rates and the development of physical dependence was assessed by body weight loss after naloxone challenge." | 3.66 | Acute physical dependence induced by continuous intravenous infusion of morphine or meperidine in the rat. ( Kato, R; Nakadate, T; Nakaki, T; Saito, M; Tokunaga, Y, 1981) |
| "Pain was the most common complication, although use of analgesia after 2 hours of observation was low." | 1.35 | Post-procedure surveillance in liver biopsy: how long is long enough? ( Basford, P; Bell, M; Derrett, S; Howard, R; Karageorge, G; Schultz, M; van Harselaar, K, 2008) |
| "Rats treated with morphine showed withdrawal signs such as hyperirritability, salivation, diarrhea, and weight loss." | 1.28 | Physical dependence potential of an enkephalin analog, EK-399, in rats. ( Nishida, N, 1990) |
| " Chronic administration of codeine (0." | 1.27 | Urinary sex-dependent low molecular weight proteins as a sign of narcotic dependence in male rats. ( Akiba, I; Endou, H; Sakai, F; Suzuki, T; Yanaura, S, 1983) |
| "Rats treated with morphine exhibited body weight loss upon the naloxone injection." | 1.27 | Effect of opioid agonist-antagonist interaction on morphine dependence in rats. ( Fukagawa, Y; Suzuki, T; Yanaura, S; Yoshii, T, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (92.11) | 18.7374 |
| 1990's | 2 (5.26) | 18.2507 |
| 2000's | 1 (2.63) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Inoue, H | 1 |
| May, EL | 1 |
| Reifenrath, WG | 1 |
| Roche, EB | 1 |
| Al-Turk, WA | 1 |
| Johnson, HL | 1 |
| Howard, R | 1 |
| Karageorge, G | 1 |
| van Harselaar, K | 1 |
| Bell, M | 1 |
| Basford, P | 1 |
| Schultz, M | 1 |
| Derrett, S | 1 |
| ROLO, A | 1 |
| Margolis, J | 1 |
| Suzuki, T | 4 |
| Yoshii, T | 2 |
| Yanaura, S | 6 |
| Akiba, I | 2 |
| Endou, H | 2 |
| Sakai, F | 2 |
| Nakaki, T | 1 |
| Saito, M | 1 |
| Nakadate, T | 1 |
| Tokunaga, Y | 1 |
| Kato, R | 1 |
| Fraser, HF | 1 |
| Gorodetzky, CW | 1 |
| Kay, DC | 1 |
| Yeh, SY | 1 |
| Haggerty, JJ | 1 |
| Slatkoff, S | 1 |
| Olivé, JM | 1 |
| Masana, L | 1 |
| González, J | 1 |
| Carrère, J | 1 |
| Roux, JM | 1 |
| Lal, H | 1 |
| Gianutsos, G | 1 |
| Puri, SK | 1 |
| Tagashira, E | 1 |
| Izumi, T | 2 |
| Iorio, LC | 1 |
| Deacon, MA | 1 |
| Ryan, EA | 1 |
| Tagashire, E | 1 |
| Nishida, N | 1 |
| Cilip, M | 1 |
| Chelluri, L | 1 |
| Jastremski, M | 1 |
| Baily, R | 1 |
| Jimenez, AC | 1 |
| Gusmorino, P | 1 |
| Pinter, I | 1 |
| Snow, B | 1 |
| Fukagawa, Y | 1 |
| Gillman, MA | 1 |
| Lichtigfeld, FJ | 1 |
| Clarke, FH | 1 |
| Hill, RT | 1 |
| Saelens, JK | 1 |
| Yokoyama, N | 1 |
| Teiger, DG | 1 |
| Kaneto, H | 2 |
| Koida, M | 2 |
| Nakanishi, H | 2 |
| Nurimoto, S | 1 |
| Sasano, H | 1 |
| Miller, RR | 1 |
| Feingold, A | 1 |
| Paxinos, J | 1 |
| Cushman, P | 1 |
| Glatt, MM | 2 |
| Marshall, I | 1 |
| Weinstock, M | 1 |
| Lorenzetti, OJ | 1 |
| Sancilio, LF | 1 |
| Weeks, JR | 2 |
| Collins, RJ | 2 |
| Huidobro, F | 1 |
| Maggiolo, C | 1 |
3 reviews available for meperidine and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Possible influence of opioid normetabolites on the onset, magnitude and quality of the opioid abstinence syndrome.
Topics: Administration, Oral; Animals; Biotransformation; Body Weight; Codeine; Dealkylation; Dextropropoxyp | 1980 |
Antagonists in the 5-phenyl-benzomorphan series.
Topics: Analgesics; Animals; Chemical Phenomena; Chemistry; Codeine; Drug Tolerance; Guinea Pigs; Half-Life; | 1973 |
Propoxyphene hydrochloride. A critical review.
Topics: Analgesics; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Female; Headac | 1970 |
1 trial available for meperidine and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Propoxyphene hydrochloride. A critical review.
Topics: Analgesics; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Female; Headac | 1970 |
35 other studies available for meperidine and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Synthesis and pharmacology of 2,9alpha-dimethyl-2'-hydroxy-6,7-benzomorphan.
Topics: Analgesics; Animals; Benzomorphans; Haplorhini; Humans; Male; Mice; Molecular Conformation; Morphina | 1976 |
Synthesis and biological activity of fluoroalkylamine derivatives of narcotic analgesics.
Topics: Analgesics, Opioid; Animals; Benzomorphans; Guinea Pigs; Haplorhini; Humans; Male; Meperidine; Mice; | 1980 |
Post-procedure surveillance in liver biopsy: how long is long enough?
Topics: Adult; Aged; Analgesics, Opioid; Biopsy; Central Nervous System Depressants; Continuity of Patient C | 2008 |
Promazine for management of the drug abstinence syndrome; rapid withdrawal of meperidine in a severely addicted patient.
Topics: Behavior, Addictive; Humans; Meperidine; Phenothiazines; Promazine; Substance Withdrawal Syndrome; S | 1957 |
HYPOTENSION of narcotic withdrawal.
Topics: Behavior, Addictive; Humans; Hypotension; Medical Records; Meperidine; Narcotics; Substance Withdraw | 1958 |
Codeine addiction with death possibly due to abrupt withdrawal.
Topics: Ankylosis; Arthritis, Rheumatoid; Codeine; Humans; Male; Meperidine; Middle Aged; Substance Withdraw | 1967 |
[Assessment of morphine-type physical dependence liability in mice using the drug-admixed food method].
Topics: Administration, Oral; Animals; Codeine; Disease Models, Animal; Humans; Male; Meperidine; Mice; Mice | 1984 |
Narcotic physical dependence and urinary sex-dependent low molecular weight proteins in male rats.
Topics: Animals; Female; Humans; Male; Meperidine; Molecular Weight; Morphine; Naloxone; Opioid-Related Diso | 1983 |
Urinary sex-dependent low molecular weight proteins as a sign of narcotic dependence in male rats.
Topics: Albuminuria; Animals; Codeine; Humans; Male; Meperidine; Molecular Weight; Opioid-Related Disorders; | 1983 |
Acute physical dependence induced by continuous intravenous infusion of morphine or meperidine in the rat.
Topics: Animals; Body Weight; Humans; Infusions, Parenteral; Male; Meperidine; Morphine; Morphine Dependence | 1981 |
Clonidine therapy and meperidine withdrawal.
Topics: Adult; Clonidine; Female; Humans; Meperidine; Substance Withdrawal Syndrome | 1981 |
Meperidine and reversible parkinsonism.
Topics: Adult; Benserazide; Drug Therapy, Combination; Humans; Levodopa; Male; Meperidine; Neurologic Examin | 1994 |
[Sulpiride in the withdrawal of non-ethylic drug addiction].
Topics: Anti-Anxiety Agents; Antiparkinson Agents; Female; Humans; Hypnotics and Sedatives; Male; Meperidine | 1976 |
A comparison of narcotic analgesics with neuroleptics on behavioral measures of dopaminergic activity.
Topics: Aggression; Amphetamine; Analgesics, Opioid; Animals; Apomorphine; Behavior, Animal; Brain; Cataleps | 1975 |
Screening method for drug dependence liability using drug-admixed food (DAF) method.
Topics: Animals; Barbiturates; Codeine; Drug Evaluation, Preclinical; Food; Humans; Male; Meperidine; Method | 1979 |
Blockade by narcotic drugs of naloxone-precipitated jumping in morphine-dependent mice.
Topics: Administration, Oral; Animals; Apomorphine; Behavior, Animal; Codeine; Dextropropoxyphene; Dose-Resp | 1975 |
[A study on drug dependence using fast acting drugs].
Topics: Animals; Body Weight; Feeding Behavior; Humans; Levallorphan; Male; Meperidine; Morphine; Rats; Subs | 1975 |
Physical dependence potential of an enkephalin analog, EK-399, in rats.
Topics: Animals; Body Weight; Enkephalins; Infusions, Intravenous; Male; Meperidine; Morphine; Naloxone; Opi | 1990 |
Continuous intravenous infusion of sodium thiopental for managing drug withdrawal syndromes.
Topics: Adult; Ethanol; Female; Humans; Infusions, Intravenous; Male; Meperidine; Middle Aged; Respiration, | 1986 |
The use of clonidine for the treatment of meperidine withdrawal in a multidisciplinary pain program setting. A case presentation.
Topics: Adult; Clonidine; Combined Modality Therapy; Drug Administration Schedule; Female; Humans; Meperidin | 1987 |
Effect of opioid agonist-antagonist interaction on morphine dependence in rats.
Topics: Animals; Benzomorphans; Body Weight; Codeine; Male; Meperidine; Morphine; Naloxone; Pentazocine; Rat | 1988 |
Analgesic nitrous oxide: adjunct to clonidine for opioid withdrawal.
Topics: Adult; Clonidine; Drug Therapy, Combination; Female; Humans; Meperidine; Morphine; Morphine Dependen | 1985 |
Induction of physical dependence on morphine, codeine and meperidine in the rat by continuous infusion.
Topics: Animals; Behavior, Animal; Body Weight; Codeine; Dose-Response Relationship, Drug; Humans; Infusions | 1974 |
Studies on physical dependence inducible by hours exposure of mice to morphine.
Topics: Analgesia; Animals; Behavior, Animal; Body Weight; Drug Tolerance; Humans; Infusions, Parenteral; In | 1972 |
A simple method for evaluating physical dependence liability in rats.
Topics: Aminopyrine; Animals; Azepines; Body Weight; Codeine; Cyproheptadine; Dextropropoxyphene; Humans; Ma | 1973 |
A scoring system for abstinence syndrome in morphine dependent mice and application to evaluate morphine type dependence liability of drugs.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Humans; Male; Meperidine; Methadone; Mi | 1973 |
Methadone maintenance therapy for heroin addiction. Some surgical considerations.
Topics: Adult; Cardiac Surgical Procedures; Curettage; Dextropropoxyphene; Dilatation; Female; Fracture Fixa | 1972 |
Treatment of morphine-type dependence by withdrawal methods.
Topics: Barbiturates; Female; Heroin; Hospitalization; Humans; Male; Meperidine; Methadone; Morphine; Pregna | 1972 |
The treatment of the withdrawal stage in narcotic addicts by diphenoxylate and chlormethiazole.
Topics: Adolescent; Adult; Atropine; Chlormethiazole; Cyanides; Drug Combinations; Evaluation Studies as Top | 1972 |
Chlormethiazole treatment of abstinence symptoms after drug withdrawal. Preliminary reports. II.
Topics: Adult; Cocaine; Female; Heroin; Humans; Hypnotics and Sedatives; Male; Meperidine; Substance Withdra | 1966 |
A quantitative method for the assessment of physical dependence on narcotic analgesics in mice.
Topics: Animals; Humans; Meperidine; Methadone; Methods; Mice; Morphine Dependence; Motor Activity; Nalorphi | 1969 |
Morphine dependent rats as a model for evaluating potential addiction liability of analgesic compounds.
Topics: Analgesics; Animals; Apomorphine; Azepines; Behavior, Animal; Codeine; Dextropropoxyphene; Diphenhyd | 1970 |
XXII. Patterns of intravenous self-injection by morphine-addicted rats.
Topics: Animals; Behavior, Animal; Benzimidazoles; Codeine; Conditioning, Operant; Drug Tolerance; Electroen | 1968 |
Factors affecting voluntary morphine intake in self-maintained addicted rats.
Topics: Animals; Behavior, Animal; Benzimidazoles; Codeine; Drug Tolerance; Humans; Infusions, Parenteral; M | 1964 |
Studies on morphine. IX. On the intensity of the abstinence syndrome to morphine induced by daily injections of nalorphine in white mice.
Topics: Animals; Drug Tolerance; Ethylamines; Humans; Levallorphan; Meperidine; Mice; Morphine Dependence; N | 1965 |