meperidine has been researched along with Delirium in 8 studies
Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.
Delirium: A disorder characterized by CONFUSION; inattentiveness; disorientation; ILLUSIONS; HALLUCINATIONS; agitation; and in some instances autonomic nervous system overactivity. It may result from toxic/metabolic conditions or structural brain lesions. (From Adams et al., Principles of Neurology, 6th ed, pp411-2)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A young patient had unexpected and prolonged postoperative delirium apparently associated with morphine-induced biliary colic." | 7.70 | Pethidine reverses morphine-induced delirium. ( McLoughlin, PD, 2000) |
| "Despite the widespread use of meperidine as an analgesic, its potential for producing delirium has been overlooked." | 7.67 | Meperidine-induced delirium. ( Dimatteo, L; Douglas, J; Eisendrath, SJ; Goldman, B; Van Dyke, C, 1987) |
| "The delirium-free protocol (DFP) group was given an intramuscular injection of diazepam at 20:00 h each night, as well as a continuous intravenous infusion of flunitrazepam and pethidine administered over 8 h, for the first three nights postoperatively." | 5.10 | A novel approach to the prevention of postoperative delirium in the elderly after gastrointestinal surgery. ( Aizawa, K; Kanai, T; Kawano, Y; Miyazawa, N; Saikawa, Y; Takabayashi, T; Yamamoto, T, 2002) |
| "Some data suggest that meperidine may lead to a higher perioperative risk for delirium; however, high-quality studies that compare different opioids are lacking." | 4.95 | The Comparative Risk of Delirium with Different Opioids: A Systematic Review. ( de Rooij, SE; Spies, PE; Swart, LM; van der Zanden, V; van Munster, BC, 2017) |
| "A young patient had unexpected and prolonged postoperative delirium apparently associated with morphine-induced biliary colic." | 3.70 | Pethidine reverses morphine-induced delirium. ( McLoughlin, PD, 2000) |
| "Despite the widespread use of meperidine as an analgesic, its potential for producing delirium has been overlooked." | 3.67 | Meperidine-induced delirium. ( Dimatteo, L; Douglas, J; Eisendrath, SJ; Goldman, B; Van Dyke, C, 1987) |
| "Five cases of post narcotic delirium, somnolence or coma are interpreted as central anticholinergic syndromes as they were reversed by physostigmine." | 3.66 | [Physostigmine reversal of central anticholinergic syndrome induced by midazolam/fentanyl, benzoctamine/buprenorphine and etomidate/carticaine or by atropine/promethazine/pethidine for premedication? (author's transl)]. ( Jost, U; Ruppert, M; Schmid, A, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Swart, LM | 1 |
| van der Zanden, V | 1 |
| Spies, PE | 1 |
| de Rooij, SE | 1 |
| van Munster, BC | 1 |
| Jost, U | 1 |
| Schmid, A | 1 |
| Ruppert, M | 1 |
| Stock, SL | 1 |
| Catalano, G | 1 |
| Catalano, MC | 1 |
| Hogan, DB | 1 |
| McLoughlin, PD | 1 |
| Aizawa, K | 1 |
| Kanai, T | 1 |
| Saikawa, Y | 1 |
| Takabayashi, T | 1 |
| Kawano, Y | 1 |
| Miyazawa, N | 1 |
| Yamamoto, T | 1 |
| Eisendrath, SJ | 1 |
| Goldman, B | 1 |
| Douglas, J | 1 |
| Dimatteo, L | 1 |
| Van Dyke, C | 1 |
| Blachly, PH | 1 |
4 reviews available for meperidine and Delirium
| Article | Year |
|---|---|
The Comparative Risk of Delirium with Different Opioids: A Systematic Review.
Topics: Aged; Analgesics, Opioid; Delirium; Humans; Hydromorphone; Meperidine; Morphine; Oxycodone; Pain; Pa | 2017 |
Meperidine associated mental status changes in a patient with chronic renal failure.
Topics: Adult; Analgesics, Opioid; Confusion; Delirium; Hallucinations; Humans; Kidney Failure, Chronic; Mal | 1996 |
Revisiting the O complex: urinary incontinence, delirium and polypharmacy in elderly patients.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Combined Modality Therapy; Delirium; Drug Interaction | 1997 |
Open-heart surgery: physiological variables of mental functioning.
Topics: Adolescent; Adult; Age Factors; Amines; Anxiety; Arrhythmias, Cardiac; Barbiturates; Bilirubin; Bloo | 1967 |
1 trial available for meperidine and Delirium
| Article | Year |
|---|---|
A novel approach to the prevention of postoperative delirium in the elderly after gastrointestinal surgery.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anti-Anxiety Agents; Delirium; Diazepam; Digestive Syst | 2002 |
3 other studies available for meperidine and Delirium
| Article | Year |
|---|---|
[Physostigmine reversal of central anticholinergic syndrome induced by midazolam/fentanyl, benzoctamine/buprenorphine and etomidate/carticaine or by atropine/promethazine/pethidine for premedication? (author's transl)].
Topics: Adult; Aged; Anthracenes; Atropine; Benzodiazepines; Buprenorphine; Carticaine; Coma; Delirium; Etom | 1982 |
Pethidine reverses morphine-induced delirium.
Topics: Adolescent; Akathisia, Drug-Induced; Analgesics, Opioid; Anesthesia Recovery Period; Biliary Tract D | 2000 |
Meperidine-induced delirium.
Topics: Adult; Aged; Delirium; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Meperidin | 1987 |