Page last updated: 2024-10-30

meperidine and Cephalgia, Vascular

meperidine has been researched along with Cephalgia, Vascular in 2 studies

Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cicek, M1
Karcioglu, O1
Parlak, I1
Ozturk, V1
Duman, O1
Serinken, M1
Guryay, M1
Belgrade, MJ1
Ling, LJ1
Schleevogt, MB1
Ettinger, MG1
Ruiz, E1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Check Trial: A Comparison of Headache Treatment in the ED: Compazine Versus Ketamine. A Multi-Center, Randomized Double-Blind, Clinical Control Trial.[NCT02657031]Phase 454 participants (Actual)Interventional2016-03-17Completed
Intravenous Fluids in Benign Headaches Trail: A Randomized Single Blind Clinical Trial[NCT03185130]Phase 458 participants (Actual)Interventional2017-05-16Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Anxiety

Reduction in 100 mm Visual Analog Scale (VAS) Score. The maximum possible change in VAS score is 100 mm, representing the complete relief of maximum anxiety. A change of 0 mm corresponds to no change in anxiety level, and a negative value indicates worsening of the anxiety after the medication. (NCT02657031)
Timeframe: 0-60 minutes

Interventionmm (Mean)
Control Arm33.7
Study Arm21.2

Headache Following Intervention

Reduction in 100 mm Visual Analog Scale (VAS) Score. Positive values represent a reduction in headache severity. The maximum possible change in VAS score is 100 mm, representing the complete relief of a maximally severe headache. A change of 0 mm corresponds to no change in headache severity, and a negative value indicates worsening of the headache after the medication. (NCT02657031)
Timeframe: 0-60 minutes

Interventionmm (Mean)
Control Arm63.5
Study Arm43.5

Nausea

Reduction in 100 mm Visual Analog Scale (VAS) Score. The maximum possible change in VAS score is 100 mm, representing the complete relief of maximum nausea. A change of 0 mm corresponds to no change in nausea level, and a negative value indicates worsening of the nausea after the medication. (NCT02657031)
Timeframe: 0-60 minutes

Interventionmm (Mean)
Control Arm38.9
Study Arm22.9

The Number of Participants Experiencing Vomiting

Yes/No (NCT02657031)
Timeframe: 0-60 minutes

Interventionparticipants (Number)
Control Arm2
Study Arm3

The Number of Patients Experiencing Restlessness

Yes/No (NCT02657031)
Timeframe: 0-60 minutes

Interventionparticipants (Number)
Control Arm3
Study Arm3

Trials

2 trials available for meperidine and Cephalgia, Vascular

ArticleYear
Prospective, randomised, double blind, controlled comparison of metoclopramide and pethidine in the emergency treatment of acute primary vascular and tension type headache episodes.
    Emergency medicine journal : EMJ, 2004, Volume: 21, Issue:3

    Topics: Adult; Analgesics, Opioid; Dopamine Antagonists; Double-Blind Method; Drug Combinations; Female; Hum

2004
Prospective, randomised, double blind, controlled comparison of metoclopramide and pethidine in the emergency treatment of acute primary vascular and tension type headache episodes.
    Emergency medicine journal : EMJ, 2004, Volume: 21, Issue:3

    Topics: Adult; Analgesics, Opioid; Dopamine Antagonists; Double-Blind Method; Drug Combinations; Female; Hum

2004
Prospective, randomised, double blind, controlled comparison of metoclopramide and pethidine in the emergency treatment of acute primary vascular and tension type headache episodes.
    Emergency medicine journal : EMJ, 2004, Volume: 21, Issue:3

    Topics: Adult; Analgesics, Opioid; Dopamine Antagonists; Double-Blind Method; Drug Combinations; Female; Hum

2004
Prospective, randomised, double blind, controlled comparison of metoclopramide and pethidine in the emergency treatment of acute primary vascular and tension type headache episodes.
    Emergency medicine journal : EMJ, 2004, Volume: 21, Issue:3

    Topics: Adult; Analgesics, Opioid; Dopamine Antagonists; Double-Blind Method; Drug Combinations; Female; Hum

2004
Comparison of single-dose meperidine, butorphanol, and dihydroergotamine in the treatment of vascular headache.
    Neurology, 1989, Volume: 39, Issue:4

    Topics: Adult; Butorphanol; Clinical Trials as Topic; Dihydroergotamine; Drug Therapy, Combination; Female;

1989