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meperidine and Body Weight

meperidine has been researched along with Body Weight in 48 studies

Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
" Rats were infused with morphine or meperidine for 24 or 48 h at constant rates and the development of physical dependence was assessed by body weight loss after naloxone challenge."3.66Acute physical dependence induced by continuous intravenous infusion of morphine or meperidine in the rat. ( Kato, R; Nakadate, T; Nakaki, T; Saito, M; Tokunaga, Y, 1981)
", n = 13) dosing (5 mg/kg), the elimination rate constants of meperidine in the effect compartment (Ke0) were 0."1.29Pharmacokinetic-pharmacodynamic modelling of meperidine in goats (II): Modelling. ( Fung, KF; Qiao, GL, 1994)
"Rats treated with morphine showed withdrawal signs such as hyperirritability, salivation, diarrhea, and weight loss."1.28Physical dependence potential of an enkephalin analog, EK-399, in rats. ( Nishida, N, 1990)
"Rats treated with morphine exhibited body weight loss upon the naloxone injection."1.27Effect of opioid agonist-antagonist interaction on morphine dependence in rats. ( Fukagawa, Y; Suzuki, T; Yanaura, S; Yoshii, T, 1988)
"Meperidine clearance was therefore evaluated in patients with traumatic injury and an effort was made to identify physiologic and/or clinical predictors of clearance which could facilitate initial dosage selection."1.27The pharmacokinetics of meperidine in acute trauma patients. ( Edwards, DJ; Hassett, JM; Kirkwood, CF; Lalka, D; Lasezkay, G; Slaughter, RL, 1986)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-199045 (93.75)18.7374
1990's2 (4.17)18.2507
2000's1 (2.08)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Glasson, JC1
Sawyer, WT1
Lindley, CM1
Ginsberg, B1
Waterhouse, RG1
Baum, D1
Brown, AC1
Church, SC1
Yeh, SY2
Krebs, HA1
Nakaki, T1
Saito, M1
Nakadate, T1
Tokunaga, Y1
Kato, R2
Jackson, MB1
Robson, PJ1
Fraser, HF1
Gorodetzky, CW1
Kay, DC1
Yanaura, S3
Uesugi, J1
Suzuki, T2
Akiyama, Y1
Low, JA1
Cox, MJ1
Karchmar, EJ1
McGrath, MJ1
Pancham, SR1
Piercy, WN1
Qiao, GL1
Fung, KF1
Peters, JH1
Gordon, GR1
Ferguson, SA1
Kirby, MJ1
Leighton, M1
Turner, P1
Pichlmayr, I1
Tagashire, E1
Izumi, T1
Nishida, N1
Fukagawa, Y1
Yoshii, T1
Brackbill, Y1
Kirkwood, CF1
Edwards, DJ1
Lalka, D1
Lasezkay, G1
Hassett, JM1
Slaughter, RL1
Morrison, CE1
Dutton, D1
Howie, H1
Gilmour, H1
Abbuhl, S1
Jacobson, S1
Murphy, JG1
Gibson, G1
Korman, B1
McKay, RJ1
Clark, RB1
Telivuo, L1
Ertama, P1
Aalto-Setälä, M1
Appelqvist, R1
Kaljunen, A1
Karhunen, U1
Nuuttila, K1
Welling, I1
Takanaka, A1
Oshima, T2
Fixler, DE1
Carrell, T1
Browne, R1
Willis, K1
Miller, WW1
Wisborg, K1
Hanel, HK1
Viby-Mogensen, J1
Teiger, DG1
Kaneto, H1
Koida, M1
Nakanishi, H1
Nurimoto, S1
Luis Ceraso, O1
Carlos Giménez, J1
Baldamus, U1
Walker, PA1
Iisalo, EU1
Vapaavuori, M1
Scott, R1
Barrie, W1
Simpson, RW1
Bell, D1
Gupta, PK1
Dundee, JW2
Morrison, JD1
Hill, GB1
Breivik, H1
Lind, B1
Wulfsohn, NL2
Banerjee, B1
Khew, KS1
Saha, N1
Ratnam, SS1
Nicák, A1
Kaltiala, EH1
Shapiro, S1
Slone, D1
Lewis, GP1
Jick, H1
Simpson, TE1
Gunnlaugsson, GH1
Dawson, B1
Lynn, HB1
Kobayashi, S1
Hasegawa, K1
Takagi, H1
Regenbrecht, J1
Rosen, MG1
Bleyer, WA1
Moore, WM1
Davis, JA1

Reviews

1 review available for meperidine and Body Weight

ArticleYear
Possible influence of opioid normetabolites on the onset, magnitude and quality of the opioid abstinence syndrome.
    Drug and alcohol dependence, 1980, Volume: 5, Issue:4

    Topics: Administration, Oral; Animals; Biotransformation; Body Weight; Codeine; Dealkylation; Dextropropoxyp

1980

Trials

7 trials available for meperidine and Body Weight

ArticleYear
Preliminary clinical and pharmacokinetic experiences in the newborn when meptazinol is compared with pethidine as an obstetric analgesic.
    Postgraduate medical journal, 1983, Volume: 59 Suppl 1

    Topics: Anesthesia, Obstetrical; Azepines; Body Weight; Double-Blind Method; Female; Humans; Infant, Newborn

1983
Pethidine compared with meptazinol during labour. A prospective randomised double-blind study in 1100 patients.
    Anaesthesia, 1987, Volume: 42, Issue:1

    Topics: Analgesia; Azepines; Body Weight; Delivery, Obstetric; Double-Blind Method; Drug Evaluation; Female;

1987
[Relative potency of morphine, meperidine and fentanyl during anesthesia with nitrous oxide].
    Revista espanola de anestesiologia y reanimacion, 1972, Volume: 19, Issue:3

    Topics: Adjuvants, Anesthesia; Adult; Aged; Anesthesia, Inhalation; Body Weight; Clinical Trials as Topic; D

1972
[Premedication for the endoscopy of lung diseases using pentazocine or pethidine and atropine].
    Medizinische Klinik, 1972, Jun-09, Volume: 67, Issue:23

    Topics: Adolescent; Adult; Age Factors; Aged; Atropine; Biopsy; Body Weight; Bronchoscopy; Clinical Trials a

1972
A double-blind comparison of pentazocine, pethidine and morphine in paediatric premedication.
    Annales chirurgiae et gynaecologiae Fenniae, 1973, Volume: 62, Issue:5

    Topics: Body Weight; Child; Child, Preschool; Clinical Trials as Topic; Female; Humans; Infant; Injections,

1973
Critique of a method of studying drugs given before anaesthesia. Summary.
    British journal of anaesthesia, 1968, Volume: 40, Issue:6

    Topics: Age Factors; Body Weight; Clinical Trials as Topic; Curettage; Female; Humans; Meperidine; Methods;

1968
Anti-emetic and propulsive peristaltic properties of metoclopramide.
    British journal of anaesthesia, 1971, Volume: 43, Issue:4

    Topics: Adult; Age Factors; Aged; Amides; Antiemetics; Auscultation; Benzoates; Body Weight; Cholecystectomy

1971

Other Studies

40 other studies available for meperidine and Body Weight

ArticleYear
Patient-specific factors affecting patient-controlled analgesia dosing.
    Journal of pain & palliative care pharmacotherapy, 2002, Volume: 16, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aged; Alcohol Drinking; Analgesia, Patient-Controlled; Analgesics, O

2002
Epileptiform convulsions in children following premedication with Pamergan SP100.
    British journal of anaesthesia, 1967, Volume: 39, Issue:3

    Topics: Body Weight; Child; Female; Humans; Injections, Intramuscular; Male; Meperidine; Promethazine; Scopo

1967
Effect of sedation on oxygen consumption of children undergoing cardiac catheterization.
    Pediatrics, 1967, Volume: 39, Issue:6

    Topics: Body Height; Body Surface Area; Body Weight; Cardiac Catheterization; Child; Child, Preschool; Femal

1967
Development of narcotic drug metabolizing enzymes in the newborn rat.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 213, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Body Weight; Carboxylic Ester Hydrolases; Female; Glucuronosyltran

1980
Acute physical dependence induced by continuous intravenous infusion of morphine or meperidine in the rat.
    Psychopharmacology, 1981, Volume: 73, Issue:3

    Topics: Animals; Body Weight; Humans; Infusions, Parenteral; Male; Meperidine; Morphine; Morphine Dependence

1981
A psychic dependence study of cinepazide in rats.
    The Journal of toxicological sciences, 1980, Volume: 5, Issue:3

    Topics: Animals; Avoidance Learning; Behavior, Animal; Body Weight; Choice Behavior; Codeine; Humans; Inject

1980
The effect of maternal, labor, and fetal factors upon fetal heart rate during the intrapartum period.
    American journal of obstetrics and gynecology, 1981, Feb-01, Volume: 139, Issue:3

    Topics: Anesthesia, Epidural; Anesthesia, Local; Body Weight; Bupivacaine; Female; Fetal Heart; Fetal Monito

1981
Pharmacokinetic-pharmacodynamic modelling of meperidine in goats (II): Modelling.
    Journal of veterinary pharmacology and therapeutics, 1994, Volume: 17, Issue:2

    Topics: Analgesia; Animals; Body Temperature; Body Weight; Brain; Evoked Potentials; Female; Goats; Heart Ra

1994
Chloral hydrate and meperidine: response and metabolism in squirrel and rehsus monkeys.
    Toxicology and applied pharmacology, 1975, Volume: 31, Issue:2

    Topics: Animals; Blood Proteins; Body Temperature; Body Weight; Chloral Hydrate; Depression, Chemical; Haplo

1975
The influence of premedication, anaesthesia, age and weight on glucose uptake into human isolated skeletal muscle.
    British journal of clinical pharmacology, 1976, Volume: 3, Issue:2

    Topics: Adult; Age Factors; Aged; Anesthesia; Atropine; Body Weight; Female; Glucose; Glycogen; Humans; Male

1976
[Premedication in childhood].
    Anasthesiologische und intensivmedizinische Praxis, 1975, Volume: 11, Issue:1

    Topics: Adolescent; Age Factors; Atropine; Benperidol; Body Weight; Child; Child, Preschool; Diazepam; Drug

1975
[A study on drug dependence using fast acting drugs].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1975, Volume: 71, Issue:4

    Topics: Animals; Body Weight; Feeding Behavior; Humans; Levallorphan; Male; Meperidine; Morphine; Rats; Subs

1975
Physical dependence potential of an enkephalin analog, EK-399, in rats.
    Japanese journal of pharmacology, 1990, Volume: 53, Issue:4

    Topics: Animals; Body Weight; Enkephalins; Infusions, Intravenous; Male; Meperidine; Morphine; Naloxone; Opi

1990
Effect of opioid agonist-antagonist interaction on morphine dependence in rats.
    Life sciences, 1988, Volume: 42, Issue:26

    Topics: Animals; Benzomorphans; Body Weight; Codeine; Male; Meperidine; Morphine; Naloxone; Pentazocine; Rat

1988
Teratogenicity for rat pups of meperidine administered postnatally, via breast milk.
    Neurotoxicology, 1986,Summer, Volume: 7, Issue:2

    Topics: Animals; Animals, Newborn; Behavior, Animal; Body Weight; Female; Meperidine; Milk; Posture; Rats; R

1986
The pharmacokinetics of meperidine in acute trauma patients.
    The Journal of trauma, 1986, Volume: 26, Issue:12

    Topics: Adult; Aged; Body Weight; Female; Humans; Kinetics; Liver; Male; Meperidine; Orosomucoid; Wounds and

1986
Serum concentrations of meperidine in patients with sickle cell crisis.
    Annals of emergency medicine, 1986, Volume: 15, Issue:4

    Topics: Absorption; Adult; Anemia, Sickle Cell; Body Weight; Chromatography, Gas; Female; Humans; Injections

1986
Steroids and postoperative analgesia.
    Anaesthesia and intensive care, 1985, Volume: 13, Issue:4

    Topics: Adult; Age Factors; Body Weight; Dexamethasone; Dose-Response Relationship, Drug; Fallopian Tubes; F

1985
Transplacental reversal of meperidine depression in the fetus by naloxone.
    The Journal of the Arkansas Medical Society, 1971, Volume: 68, Issue:4

    Topics: Allyl Compounds; Apgar Score; Body Weight; Delivery, Obstetric; Ethers, Cyclic; Female; Fetus; Human

1971
Clinical study of pancuronium bromide as a neuromuscular blocking agent in anaesthesia.
    Acta anaesthesiologica Scandinavica, 1971, Volume: 15, Issue:4

    Topics: Adult; Androstanes; Anesthesia; Atropine; Blood Pressure; Body Weight; Female; Heart Rate; Humans; I

1971
Effect of vitamin C deficiency on the metabolism of drugs and NADPH-linked electron transport system in liver microsomes.
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:1

    Topics: Aminopyrine; Aniline Compounds; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Body Weight; Diphe

1969
Oxygen consumption in infants and children during cardiac catheterization under different sedation regimens.
    Circulation, 1974, Volume: 50, Issue:4

    Topics: Age Factors; Anesthesia; Anesthesia, Intravenous; Anesthetics; Atropine; Body Surface Area; Body Tem

1974
Variations in serum potassium and serum cholinesterase activity after induction with Althesin-suxamethonium and thiopentone-suxamethonium.
    Acta anaesthesiologica Scandinavica, 1974, Volume: 18, Issue:3

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia, General; Atropine; Body Height; Body Weight; Carbon Dioxid

1974
Induction of physical dependence on morphine, codeine and meperidine in the rat by continuous infusion.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 190, Issue:3

    Topics: Animals; Behavior, Animal; Body Weight; Codeine; Dose-Response Relationship, Drug; Humans; Infusions

1974
Studies on physical dependence inducible by hours exposure of mice to morphine.
    Japanese journal of pharmacology, 1972, Volume: 22, Issue:6

    Topics: Analgesia; Animals; Behavior, Animal; Body Weight; Drug Tolerance; Humans; Infusions, Parenteral; In

1972
A simple method for evaluating physical dependence liability in rats.
    Japanese journal of pharmacology, 1973, Volume: 23, Issue:3

    Topics: Aminopyrine; Animals; Azepines; Body Weight; Codeine; Cyproheptadine; Dextropropoxyphene; Humans; Ma

1973
Drugs used in labour: an obstetrician's view.
    British journal of anaesthesia, 1973, Volume: 45

    Topics: Administration, Oral; Anesthesia, Obstetrical; Antihypertensive Agents; Body Weight; Ethanol; Fear;

1973
The use of pentazocine as a strong analgesic in urological practice.
    British journal of urology, 1973, Volume: 45, Issue:2

    Topics: Adult; Analgesics; Body Weight; Female; Humans; Injections, Intramuscular; Male; Meperidine; Middle

1973
Alterations in response to somatic pain associated with anaesthesia. XXII. Nikethamide, doxapram and naloxone.
    British journal of anaesthesia, 1973, Volume: 45, Issue:5

    Topics: Anesthesia; Body Weight; Doxapram; Female; Humans; Meperidine; Morphine; Naloxone; Nikethamide; Pain

1973
D-tubocurarine dosage based on lean body mass.
    Canadian Anaesthetists' Society journal, 1972, Volume: 19, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Anesthesia, General; Body Composition; Body Constitution; Body

1972
Succinylcholine dosage based on lean body mass.
    Canadian Anaesthetists' Society journal, 1972, Volume: 19, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Apnea; Body Weight; Female; Halothane; Humans; Intubat

1972
Energy cost and blood sugar level during different stages of labour and duration of labour in Asiatic women.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1971, Volume: 78, Issue:10

    Topics: Adolescent; Adult; Anesthesia, Obstetrical; Asian People; Basal Metabolism; Birth Weight; Blood Gluc

1971
Pethidine-induced inhbition of nociceptive stimuli in young and aged rats.
    Agents and actions, 1971, Volume: 2, Issue:1

    Topics: Age Factors; Animals; Body Weight; Brain Chemistry; Depression, Chemical; Electric Stimulation; Fema

1971
The effect of intestinal obstruction on liver microsomal enzymes in rats.
    Acta chirurgica Scandinavica. Supplementum, 1968, Volume: 402

    Topics: Anesthesia; Animals; Body Temperature; Body Weight; Chlorpromazine; Hematocrit; Intestinal Obstructi

1968
The epidemiology o digoxin. A study in three Boston hospitals.
    Journal of chronic diseases, 1969, Volume: 22, Issue:5

    Topics: Age Factors; Aged; Aminophylline; Arrhythmias, Cardiac; Body Weight; Digoxin; Epidemiologic Methods;

1969
Further experience with bilateral operations for inguinal hernia in infants and children.
    Annals of surgery, 1969, Volume: 169, Issue:3

    Topics: Adolescent; Anesthesia; Atropine; Body Weight; Child; Child, Preschool; Female; Hernia, Inguinal; Hu

1969
The pharmacology of azabicyclane, a new analgesic agent.
    Toxicology and applied pharmacology, 1970, Volume: 17, Issue:2

    Topics: Analgesics; Animals; Antitussive Agents; Body Weight; Cardiovascular System; Constriction; Digestive

1970
[116. Preoperative and postoperative care in pediatric surgery].
    Langenbecks Archiv fur Chirurgie, 1967, Volume: 319

    Topics: Adolescent; Anesthesia; Atropine; Body Fluids; Body Weight; Child; Child, Preschool; Female; Humans;

1967
Bidirectional transfer of meperidine across the guinea pig placenta.
    American journal of obstetrics and gynecology, 1968, Aug-01, Volume: 101, Issue:7

    Topics: Animals; Body Weight; Electroencephalography; Female; Fetus; Gestational Age; Guinea Pigs; Injection

1968
Response of the newborn rabbit to acute anoxia and variations due to narcotic agents.
    British journal of anaesthesia, 1966, Volume: 38, Issue:10

    Topics: Animals; Animals, Newborn; Apnea; Body Weight; Dyspnea; Hypoxia; Levallorphan; Meperidine; Morphine;

1966