Page last updated: 2024-10-30

meperidine and Apnea

meperidine has been researched along with Apnea in 25 studies

Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.

Apnea: A transient absence of spontaneous respiration.

Research Excerpts

ExcerptRelevanceReference
"A two-month-old white girl presented to our facility with increasing lethargy and new onset apnea and bradycardia following a week of upper respiratory tract infection symptoms."8.78Phenothiazine-associated apnea in two siblings. ( Blumer, JL; Buck, ML, 1991)
"Ten patients developed apnea or cardiopulmonary arrest during or following endoscopy in more than 10,000 consecutive endoscopies."7.68Apnea and cardiopulmonary arrest during and after endoscopy. ( Iber, FL; Kruss, DM; Livak, A, 1992)
" The following 4 cardiopulmonary complications were assessed: hypoxia, hypotension, arrhythmias, and apnea."4.82Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis. ( Khandwala, F; Lopez, R; Qadeer, MA; Vargo, JJ; Zuccaro, G, 2005)
"A two-month-old white girl presented to our facility with increasing lethargy and new onset apnea and bradycardia following a week of upper respiratory tract infection symptoms."4.78Phenothiazine-associated apnea in two siblings. ( Blumer, JL; Buck, ML, 1991)
"Ten patients developed apnea or cardiopulmonary arrest during or following endoscopy in more than 10,000 consecutive endoscopies."3.68Apnea and cardiopulmonary arrest during and after endoscopy. ( Iber, FL; Kruss, DM; Livak, A, 1992)
"Propofol 2."2.66The effects of premedication on anaesthesia with propofol ('Diprivan'). ( Briggs, LP; White, M, 1985)
"The authors report on adverse events and sedation outcomes for an oral sedation regimen of chloral hydrate, meperidine and hydroxyzine with 100 percent oxygen, or O2, supplementation."1.31Adverse events and outcomes of conscious sedation for pediatric patients: study of an oral sedation regimen. ( Leelataweedwud, P; Vann, WF, 2001)
"When nalorphine was combined with pethidine the period of primary apnoea was still increased although the duration and number of gasps were restored to control values."1.26The effect of narcotic and narcotic-antagonist drugs in the newborn rabbit. ( Cooper, LV; Harvey, D; Stephen, GW, 1976)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199020 (80.00)18.7374
1990's3 (12.00)18.2507
2000's2 (8.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
HERBERG, D1
GEISLER, L1
SCHENCK, P1
DAWSON, GR1
HARNIK, E1
PESCE, A1
RUGIERO, G1
Qadeer, MA1
Vargo, JJ1
Khandwala, F1
Lopez, R1
Zuccaro, G1
Moore, WM2
Davis, JA2
Wennergren, G1
Wennergren, M1
Koch, B1
Braillier, D1
Eng, G1
Binder, H1
Donnelly, MB1
Scott, WA1
Daly, DS1
Leelataweedwud, P1
Vann, WF1
Barritt, PW1
Hawkes, RA1
Jivani, SK1
Stephen, GW1
Cooper, LV1
Harvey, D1
Iber, FL1
Livak, A1
Kruss, DM1
Buck, ML1
Blumer, JL1
Clyburn, PA1
Rosen, M2
Stone, B1
Barkin, JS1
Panullo, W1
Rogers, AI1
Briggs, LP1
White, M1
Tammisto, T1
Takki, S1
Tigerstedt, I1
Kauste, A1
Mushin, WW1
Jones, PL1
Jones, EV1
Goedee, HW1
Altland, K1
Wulfsohn, NL1
Mandlekar, VM1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT02039453]160 participants (Anticipated)Interventional2013-09-30Recruiting
A Psychomotor Recuperation Study After Deep Sedation for Colonoscopy Between Target Controlled and Manual Titration of Propofol.[NCT02314559]Phase 4164 participants (Actual)Interventional2015-02-28Completed
Isolite and Dental Treatment Under Conscious Sedation: a Pilot Study to Assess the Upper Airway in a Pediatric Population[NCT01683851]20 participants (Actual)Observational2012-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for meperidine and Apnea

ArticleYear
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:11

    Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy

2005
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:11

    Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy

2005
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:11

    Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy

2005
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:11

    Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy

2005
Phenothiazine-associated apnea in two siblings.
    DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:3

    Topics: Apnea; Bradycardia; Chlorpromazine; Drug Therapy, Combination; Family; Female; Humans; Infant; Male;

1991
[Genetically dependent variability of drug effects].
    Medizinische Klinik, 1970, Aug-28, Volume: 65, Issue:35

    Topics: Anemia, Hemolytic; Anesthesia, General; Anesthetics; Animals; Antipyrine; Apnea; Atropine; Body Temp

1970

Trials

4 trials available for meperidine and Apnea

ArticleYear
Sedation for upper gastrointestinal endoscopy: a comparison of alfentanil-midazolam and meperidine-diazepam.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:12

    Topics: Age Factors; Alfentanil; Anesthesia Recovery Period; Apnea; Conscious Sedation; Diazepam; Dizziness;

1994
Patient-controlled analgesia with a mixture of pethidine and doxapram hydrochloride. A comparison of the incidence of respiratory dysrhythmias with pethidine alone.
    Anaesthesia, 1988, Volume: 43, Issue:3

    Topics: Adult; Aged; Apnea; Carbon Dioxide; Doxapram; Drug Therapy, Combination; Female; Humans; Male; Meper

1988
The effects of premedication on anaesthesia with propofol ('Diprivan').
    Postgraduate medical journal, 1985, Volume: 61 Suppl 3

    Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Apnea; Atropine; Blood Pressure; Diazepam; Female;

1985
Field trial of methoxyflurane, nitrous oxide, and trichloroethylene as obstetric analgesics.
    British medical journal, 1969, Aug-02, Volume: 3, Issue:5665

    Topics: Anesthesia, Obstetrical; Apnea; Clinical Trials as Topic; Consciousness; Female; Humans; Infant, New

1969

Other Studies

18 other studies available for meperidine and Apnea

ArticleYear
[ON THE INFLUENCE OF SOME FREQUENTLY USED SEDATIVES AND ANALGESICS ON THE HUMAN RESPIRATORY CENTER WITH SPECIAL REFERENCE TO PATIENTS WITH ALVEOLAR HYPOVENTILATION].
    Die Medizinische Welt, 1963, Nov-02, Volume: 44

    Topics: Analgesics; Apnea; Humans; Hypnotics and Sedatives; Hypoventilation; Medulla Oblongata; Meperidine;

1963
A CASE OF POST-OPERATIVE APNOEA RESPONDING TO INTRAVENOUS SODIUM BICARBONATE INFUSION.
    The Medical journal of Australia, 1964, Apr-04, Volume: 1

    Topics: Acidosis; Apnea; Atropine; Bicarbonates; Bis-Trimethylammonium Compounds; Gallamine Triethiodide; Hu

1964
A STUDY OF THE BIPHASIC VENTILATORY EFFECTS OF PROPANIDID.
    British journal of anaesthesia, 1964, Volume: 36

    Topics: Adolescent; Anesthetics; Apnea; Atropine; Child; Chlorpromazine; Geriatrics; Hiccup; Humans; Meperid

1964
[CONTROLLABLE APNEA IN ANESTHESIA BY MEANS OF CENTRAL DEPRESSION DUE TO ANALGESICS].
    Gazzetta internazionale di medicina e chirurgia, 1964, Nov-30, Volume: 68

    Topics: Analgesics; Anesthesia; Apnea; Central Nervous System Agents; Depression; Dextromoramide; Humans; Me

1964
Simultaneous administration of narcotic and narcotic-antagonist drugs in the newborn rabbit.
    The Journal of pediatrics, 1967, Volume: 71, Issue:3

    Topics: Animals; Animals, Newborn; Apnea; Asphyxia Neonatorum; Dyspnea; Humans; Hypoxia; Infant, Newborn; Le

1967
Meptazinol.
    Lancet (London, England), 1983, Aug-13, Volume: 2, Issue:8346

    Topics: Anesthesia, Obstetrical; Animals; Apnea; Azepines; Female; Humans; Infant, Newborn; Meperidine; Mept

1983
Neonatal breathing control mediated via the central chemoreceptors.
    Acta physiologica Scandinavica, 1983, Volume: 119, Issue:2

    Topics: Animals; Animals, Newborn; Apnea; Carbon Dioxide; Cerebrospinal Fluid; Chemoreceptor Cells; Guinea P

1983
Computerized tomography in cerebral-palsied children.
    Developmental medicine and child neurology, 1980, Volume: 22, Issue:5

    Topics: Adolescent; Apnea; Brain; Cerebral Palsy; Child; Child, Preschool; Hemiplegia; Humans; Infant; Infan

1980
Adverse events and outcomes of conscious sedation for pediatric patients: study of an oral sedation regimen.
    Journal of the American Dental Association (1939), 2001, Volume: 132, Issue:11

    Topics: Administration, Oral; Analgesics, Opioid; Analysis of Variance; Anesthesia Recovery Period; Anesthes

2001
Maternal pethidine and neonatal depression.
    British medical journal, 1978, Jan-14, Volume: 1, Issue:6105

    Topics: Apnea; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Levallorphan; Meperidine; Naloxon

1978
The effect of narcotic and narcotic-antagonist drugs in the newborn rabbit.
    British journal of anaesthesia, 1976, Volume: 48, Issue:7

    Topics: Animals; Apnea; Dyspnea; Humans; Hypoxia; Infant, Newborn; Meperidine; Morphine; Nalorphine; Naloxon

1976
Apnea and cardiopulmonary arrest during and after endoscopy.
    Journal of clinical gastroenterology, 1992, Volume: 14, Issue:2

    Topics: Aged; Apnea; Butorphanol; Databases, Factual; Diazepam; Endoscopy, Gastrointestinal; Heart Arrest; H

1992
Hypercalcemia: a risk factor to patients undergoing gastrointestinal endoscopy.
    The American journal of gastroenterology, 1986, Volume: 81, Issue:7

    Topics: Aged; Apnea; Carcinoma, Squamous Cell; Diazepam; Drug Synergism; Esophageal Neoplasms; Esophagoscopy

1986
Editorial: Obstetric analgesia and the newborn baby.
    Lancet (London, England), 1974, Jun-01, Volume: 1, Issue:7866

    Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Apnea; Delivery, Obstetric; Female; Humans; Infant, N

1974
A comparison of althesin and thiopentone in induction of anaesthesia.
    British journal of anaesthesia, 1973, Volume: 45, Issue:1

    Topics: Adult; Aged; Anesthesia, Intravenous; Apnea; Atropine; Blood Pressure; Dose-Response Relationship, D

1973
Succinylcholine dosage based on lean body mass.
    Canadian Anaesthetists' Society journal, 1972, Volume: 19, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Apnea; Body Weight; Female; Halothane; Humans; Intubat

1972
Accidental total spinal (intradural) block. A case with some unusual features.
    Anaesthesia, 1970, Volume: 25, Issue:3

    Topics: Adult; Anesthesia, Spinal; Apnea; Atropine; Epinephrine; Humans; Lidocaine; Male; Meperidine; Paraly

1970
Response of the newborn rabbit to acute anoxia and variations due to narcotic agents.
    British journal of anaesthesia, 1966, Volume: 38, Issue:10

    Topics: Animals; Animals, Newborn; Apnea; Body Weight; Dyspnea; Hypoxia; Levallorphan; Meperidine; Morphine;

1966