meperidine and Apnea
meperidine has been researched along with Apnea in 25 studies
Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.
Apnea: A transient absence of spontaneous respiration.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "A two-month-old white girl presented to our facility with increasing lethargy and new onset apnea and bradycardia following a week of upper respiratory tract infection symptoms." | 8.78 | Phenothiazine-associated apnea in two siblings. ( Blumer, JL; Buck, ML, 1991) |
| "Ten patients developed apnea or cardiopulmonary arrest during or following endoscopy in more than 10,000 consecutive endoscopies." | 7.68 | Apnea and cardiopulmonary arrest during and after endoscopy. ( Iber, FL; Kruss, DM; Livak, A, 1992) |
| " The following 4 cardiopulmonary complications were assessed: hypoxia, hypotension, arrhythmias, and apnea." | 4.82 | Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis. ( Khandwala, F; Lopez, R; Qadeer, MA; Vargo, JJ; Zuccaro, G, 2005) |
| "A two-month-old white girl presented to our facility with increasing lethargy and new onset apnea and bradycardia following a week of upper respiratory tract infection symptoms." | 4.78 | Phenothiazine-associated apnea in two siblings. ( Blumer, JL; Buck, ML, 1991) |
| "Ten patients developed apnea or cardiopulmonary arrest during or following endoscopy in more than 10,000 consecutive endoscopies." | 3.68 | Apnea and cardiopulmonary arrest during and after endoscopy. ( Iber, FL; Kruss, DM; Livak, A, 1992) |
| "Propofol 2." | 2.66 | The effects of premedication on anaesthesia with propofol ('Diprivan'). ( Briggs, LP; White, M, 1985) |
| "The authors report on adverse events and sedation outcomes for an oral sedation regimen of chloral hydrate, meperidine and hydroxyzine with 100 percent oxygen, or O2, supplementation." | 1.31 | Adverse events and outcomes of conscious sedation for pediatric patients: study of an oral sedation regimen. ( Leelataweedwud, P; Vann, WF, 2001) |
| "When nalorphine was combined with pethidine the period of primary apnoea was still increased although the duration and number of gasps were restored to control values." | 1.26 | The effect of narcotic and narcotic-antagonist drugs in the newborn rabbit. ( Cooper, LV; Harvey, D; Stephen, GW, 1976) |
Research
Studies (25)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (80.00) | 18.7374 |
| 1990's | 3 (12.00) | 18.2507 |
| 2000's | 2 (8.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| HERBERG, D | 1 |
| GEISLER, L | 1 |
| SCHENCK, P | 1 |
| DAWSON, GR | 1 |
| HARNIK, E | 1 |
| PESCE, A | 1 |
| RUGIERO, G | 1 |
| Qadeer, MA | 1 |
| Vargo, JJ | 1 |
| Khandwala, F | 1 |
| Lopez, R | 1 |
| Zuccaro, G | 1 |
| Moore, WM | 2 |
| Davis, JA | 2 |
| Wennergren, G | 1 |
| Wennergren, M | 1 |
| Koch, B | 1 |
| Braillier, D | 1 |
| Eng, G | 1 |
| Binder, H | 1 |
| Donnelly, MB | 1 |
| Scott, WA | 1 |
| Daly, DS | 1 |
| Leelataweedwud, P | 1 |
| Vann, WF | 1 |
| Barritt, PW | 1 |
| Hawkes, RA | 1 |
| Jivani, SK | 1 |
| Stephen, GW | 1 |
| Cooper, LV | 1 |
| Harvey, D | 1 |
| Iber, FL | 1 |
| Livak, A | 1 |
| Kruss, DM | 1 |
| Buck, ML | 1 |
| Blumer, JL | 1 |
| Clyburn, PA | 1 |
| Rosen, M | 2 |
| Stone, B | 1 |
| Barkin, JS | 1 |
| Panullo, W | 1 |
| Rogers, AI | 1 |
| Briggs, LP | 1 |
| White, M | 1 |
| Tammisto, T | 1 |
| Takki, S | 1 |
| Tigerstedt, I | 1 |
| Kauste, A | 1 |
| Mushin, WW | 1 |
| Jones, PL | 1 |
| Jones, EV | 1 |
| Goedee, HW | 1 |
| Altland, K | 1 |
| Wulfsohn, NL | 1 |
| Mandlekar, VM | 1 |
Clinical Trials (3)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT02039453] | 160 participants (Anticipated) | Interventional | 2013-09-30 | Recruiting | |||
| A Psychomotor Recuperation Study After Deep Sedation for Colonoscopy Between Target Controlled and Manual Titration of Propofol.[NCT02314559] | Phase 4 | 164 participants (Actual) | Interventional | 2015-02-28 | Completed | ||
| Isolite and Dental Treatment Under Conscious Sedation: a Pilot Study to Assess the Upper Airway in a Pediatric Population[NCT01683851] | 20 participants (Actual) | Observational | 2012-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reviews
3 reviews available for meperidine and Apnea
| Article | Year |
|---|---|
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy | 2005 |
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy | 2005 |
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy | 2005 |
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy | 2005 |
Phenothiazine-associated apnea in two siblings.
Topics: Apnea; Bradycardia; Chlorpromazine; Drug Therapy, Combination; Family; Female; Humans; Infant; Male; | 1991 |
[Genetically dependent variability of drug effects].
Topics: Anemia, Hemolytic; Anesthesia, General; Anesthetics; Animals; Antipyrine; Apnea; Atropine; Body Temp | 1970 |
Trials
4 trials available for meperidine and Apnea
| Article | Year |
|---|---|
Sedation for upper gastrointestinal endoscopy: a comparison of alfentanil-midazolam and meperidine-diazepam.
Topics: Age Factors; Alfentanil; Anesthesia Recovery Period; Apnea; Conscious Sedation; Diazepam; Dizziness; | 1994 |
Patient-controlled analgesia with a mixture of pethidine and doxapram hydrochloride. A comparison of the incidence of respiratory dysrhythmias with pethidine alone.
Topics: Adult; Aged; Apnea; Carbon Dioxide; Doxapram; Drug Therapy, Combination; Female; Humans; Male; Meper | 1988 |
The effects of premedication on anaesthesia with propofol ('Diprivan').
Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Apnea; Atropine; Blood Pressure; Diazepam; Female; | 1985 |
Field trial of methoxyflurane, nitrous oxide, and trichloroethylene as obstetric analgesics.
Topics: Anesthesia, Obstetrical; Apnea; Clinical Trials as Topic; Consciousness; Female; Humans; Infant, New | 1969 |
Other Studies
18 other studies available for meperidine and Apnea
| Article | Year |
|---|---|
[ON THE INFLUENCE OF SOME FREQUENTLY USED SEDATIVES AND ANALGESICS ON THE HUMAN RESPIRATORY CENTER WITH SPECIAL REFERENCE TO PATIENTS WITH ALVEOLAR HYPOVENTILATION].
Topics: Analgesics; Apnea; Humans; Hypnotics and Sedatives; Hypoventilation; Medulla Oblongata; Meperidine; | 1963 |
A CASE OF POST-OPERATIVE APNOEA RESPONDING TO INTRAVENOUS SODIUM BICARBONATE INFUSION.
Topics: Acidosis; Apnea; Atropine; Bicarbonates; Bis-Trimethylammonium Compounds; Gallamine Triethiodide; Hu | 1964 |
A STUDY OF THE BIPHASIC VENTILATORY EFFECTS OF PROPANIDID.
Topics: Adolescent; Anesthetics; Apnea; Atropine; Child; Chlorpromazine; Geriatrics; Hiccup; Humans; Meperid | 1964 |
[CONTROLLABLE APNEA IN ANESTHESIA BY MEANS OF CENTRAL DEPRESSION DUE TO ANALGESICS].
Topics: Analgesics; Anesthesia; Apnea; Central Nervous System Agents; Depression; Dextromoramide; Humans; Me | 1964 |
Simultaneous administration of narcotic and narcotic-antagonist drugs in the newborn rabbit.
Topics: Animals; Animals, Newborn; Apnea; Asphyxia Neonatorum; Dyspnea; Humans; Hypoxia; Infant, Newborn; Le | 1967 |
Meptazinol.
Topics: Anesthesia, Obstetrical; Animals; Apnea; Azepines; Female; Humans; Infant, Newborn; Meperidine; Mept | 1983 |
Neonatal breathing control mediated via the central chemoreceptors.
Topics: Animals; Animals, Newborn; Apnea; Carbon Dioxide; Cerebrospinal Fluid; Chemoreceptor Cells; Guinea P | 1983 |
Computerized tomography in cerebral-palsied children.
Topics: Adolescent; Apnea; Brain; Cerebral Palsy; Child; Child, Preschool; Hemiplegia; Humans; Infant; Infan | 1980 |
Adverse events and outcomes of conscious sedation for pediatric patients: study of an oral sedation regimen.
Topics: Administration, Oral; Analgesics, Opioid; Analysis of Variance; Anesthesia Recovery Period; Anesthes | 2001 |
Maternal pethidine and neonatal depression.
Topics: Apnea; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Levallorphan; Meperidine; Naloxon | 1978 |
The effect of narcotic and narcotic-antagonist drugs in the newborn rabbit.
Topics: Animals; Apnea; Dyspnea; Humans; Hypoxia; Infant, Newborn; Meperidine; Morphine; Nalorphine; Naloxon | 1976 |
Apnea and cardiopulmonary arrest during and after endoscopy.
Topics: Aged; Apnea; Butorphanol; Databases, Factual; Diazepam; Endoscopy, Gastrointestinal; Heart Arrest; H | 1992 |
Hypercalcemia: a risk factor to patients undergoing gastrointestinal endoscopy.
Topics: Aged; Apnea; Carcinoma, Squamous Cell; Diazepam; Drug Synergism; Esophageal Neoplasms; Esophagoscopy | 1986 |
Editorial: Obstetric analgesia and the newborn baby.
Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Apnea; Delivery, Obstetric; Female; Humans; Infant, N | 1974 |
A comparison of althesin and thiopentone in induction of anaesthesia.
Topics: Adult; Aged; Anesthesia, Intravenous; Apnea; Atropine; Blood Pressure; Dose-Response Relationship, D | 1973 |
Succinylcholine dosage based on lean body mass.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Apnea; Body Weight; Female; Halothane; Humans; Intubat | 1972 |
Accidental total spinal (intradural) block. A case with some unusual features.
Topics: Adult; Anesthesia, Spinal; Apnea; Atropine; Epinephrine; Humans; Lidocaine; Male; Meperidine; Paraly | 1970 |
Response of the newborn rabbit to acute anoxia and variations due to narcotic agents.
Topics: Animals; Animals, Newborn; Apnea; Body Weight; Dyspnea; Hypoxia; Levallorphan; Meperidine; Morphine; | 1966 |