meperidine has been researched along with Alcoholic Cirrhosis in 2 studies
Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the bioavailability and disposition kinetics of pethidine and pentazocine in patients with alcoholic cirrhosis and age-matched healthy subjects." | 3.66 | Enhanced bioavailability of pethidine and pentazocine in patients with cirrhosis of the liver. ( Benowitz, NL; Jacob, P; Pond, SM; Tong, T, 1980) |
| " Systemic clearance of meperidine was smaller and bioavailability and half-life greater in the cirrhotic patients than in the normal subjects." | 1.26 | Presystemic metabolism of meperidine to normeperidine in normal and cirrhotic subjects. ( Benowitz, NL; Jacob, P; Pond, SM; Rigod, J; Tong, T, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pond, SM | 2 |
| Tong, T | 2 |
| Benowitz, NL | 2 |
| Jacob, P | 2 |
| Rigod, J | 1 |
2 other studies available for meperidine and Alcoholic Cirrhosis
| Article | Year |
|---|---|
Enhanced bioavailability of pethidine and pentazocine in patients with cirrhosis of the liver.
Topics: Administration, Oral; Adult; Biological Availability; Dose-Response Relationship, Drug; Half-Life; H | 1980 |
Presystemic metabolism of meperidine to normeperidine in normal and cirrhotic subjects.
Topics: Administration, Oral; Adult; Biotransformation; Dealkylation; Humans; Injections, Intravenous; Kinet | 1981 |