meperidine has been researched along with Acute Liver Injury, Drug-Induced in 9 studies
Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Morphine and pethidine were used as markers of hepatic glucuronidation and oxidation, respectively." | 1.29 | Factors affecting the hepatic elimination of oxidized and of glucoronidated high clearance drugs following acute administration of carbon tetrachloride. ( Callaghan, R; Desmond, PV; Mashford, ML; Paull, P, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 2 |
| Sakatis, MZ | 1 |
| Reese, MJ | 1 |
| Harrell, AW | 1 |
| Taylor, MA | 1 |
| Baines, IA | 1 |
| Chen, L | 1 |
| Bloomer, JC | 1 |
| Yang, EY | 1 |
| Ellens, HM | 1 |
| Ambroso, JL | 1 |
| Lovatt, CA | 1 |
| Ayrton, AD | 1 |
| Clarke, SE | 1 |
| Chen, M | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| FISCHER, A | 1 |
| TAKACS, L | 1 |
| VARGA, I | 1 |
| Kluender, CN | 1 |
| Klein, R | 1 |
| Kohler, B | 1 |
| Callaghan, R | 1 |
| Paull, P | 1 |
| Desmond, PV | 1 |
| Mashford, ML | 1 |
| Scalley, RD | 1 |
| Conner, CS | 1 |
| Ananth, JV | 1 |
| Ban, TA | 1 |
| Lehmann, HE | 1 |
1 review available for meperidine and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
8 other studies available for meperidine and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme | 2012 |
[STUDY OF THE INTERMEDIATE METABOLISM OF DRUGS USING PARTIAL HEPATECTOMY].
Topics: Barbiturates; Caffeine; Chemical and Drug Induced Liver Injury; Chloralose; Hepatectomy; Hepatitis; | 1963 |
Dramatic increase in bilirubin after ERCP - pethidine as a possible cause of drug-induced hepatitis.
Topics: Adjuvants, Anesthesia; Aged; Bilirubin; Chemical and Drug Induced Liver Injury; Cholangiopancreatogr | 2003 |
Factors affecting the hepatic elimination of oxidized and of glucoronidated high clearance drugs following acute administration of carbon tetrachloride.
Topics: Acute Disease; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Gluc | 1994 |
Acetaminophen poisoning: a case report of the use of acetylcysteine.
Topics: Acetaminophen; Acetylcysteine; Adult; Chemical and Drug Induced Liver Injury; Codeine; Female; Human | 1978 |
Tolbutamide jundice associated with multiple drug therapy.
Topics: Adjustment Disorders; Aged; Chemical and Drug Induced Liver Injury; Dextroamphetamine; Diabetes Mell | 1970 |