meperidine has been researched along with Acute Hypercapnic Respiratory Failure in 57 studies
Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "One hundred and twenty-eight term nulliparous women with singleton pregnancy and vertex presentation were randomized to receive either epidural (n=43), meperidine (n=39) or tramadol (n=44)." | 5.10 | Analgesic efficacy of intramuscular opioids versus epidural analgesia in labor. ( Arya, VK; Gopalan, S; Jain, S; Jain, V, 2003) |
| " The authors suggest the use of the new reversal agent suggamadex, for reversing neuromuscular blockade caused by rocuronium, in patients suffering from neuromuscular disease and especially from Myotonic Dystrophy, because it rapidly and completely reverses any residual neuromuscular blockade, but also underline the increased susceptibility of these patients to opioids." | 3.77 | Anesthesia for laparoscopic surgery in a patient with myotonic dystrophy (Steinert's disease): beneficial use of sugammadex, but incorrect use of pethidine: a case report. ( Dimitriou, V; Manataki, A; Margaritis, A; Mavridou, P, 2011) |
| " Treatment of the patient and her unusual sensitivity to meperidine and promethazine that caused a depression into Cheyne-Stokes respiration and hypotension are described." | 3.65 | Serious postextraction hemorrhage into the submandibular space: report of case. ( Arthur, A; Miller, R; Sakamoto, E; Stratigos, GT, 1975) |
| "The naloxone-treated neonates were comparable with the epidural group, although the effects of naloxone were diminishing at 30 minutes." | 2.64 | Reversal of narcotic depression in the neonate by nalozone. ( Evans, JM; Hogg, MI; Rosen, M, 1976) |
| "A 20-month-old girl, with respiratory failure due to severe subcutaneous and mediastinal emphysema, was scheduled to undergo percutaneous drainage of emphysema and induction of extracorporeal membrane oxygenation." | 1.40 | [Anesthetic management of a patient with severe subcutaneous and mediastinal emphysema due to pertussis infection]. ( Ideno, S; Ishikawa, S; Mikasa, H; Miyazawa, N; Shinto, A; Wakamiya, R; Yamamoto, S, 2014) |
| "The risk of respiratory depression increased with age." | 1.32 | Side effects of opioids during short-term administration: effect of age, gender, and race. ( Baumgarten, M; Boston, R; Carr, DB; Cepeda, MS; Farrar, JT; Strom, BL, 2003) |
| " Groups were allocated based upon the dosage of meperidine administered (0, 4." | 1.30 | The influence of meperidine and nitrous oxide on respiratory depression in rats. ( Henry, RJ; Jones, DJ; Pedersen, KE, 1997) |
| "We have observed two cases of respiratory depression associated with meperidine spinal anaesthesia." | 1.29 | Respiratory depression associated with meperidine spinal anaesthesia. ( Ong, B; Segstro, R, 1994) |
| "Midazolam was the intravenous sedative used by a third of all respondents and 13% also used an additional intravenous agent, usually pethidine." | 1.28 | Sedation for upper gastrointestinal endoscopy: results of a nationwide survey. ( Bell, GD; Daneshmend, TK; Logan, RF, 1991) |
| "As regards respiratory depression, six of ten narcotic-treated monkeys had suboptimal (less than 60 breath/min) respiratory rates at birth." | 1.27 | Disposition of intrapartum narcotic analgesics in monkeys. ( Eisele, JH; Golub, MS; Kuhnert, BR, 1988) |
| "The response in the newborn rabbit to anoxia, is periods of dyspnoea, primary apnoea, and gasping." | 1.26 | The role of analgesics in respiratory depression: a rabbit model. ( Cooper, LV; Stephen, GW, 1977) |
| "1." | 1.26 | [Anesthesia in pacemaker implantation. Experiences in 935 cases of anesthesia for the implantation or revision of a cardiac pacemaker]. ( Blaum, U; Pflüger, H; Schmidt, H, 1977) |
| "Secondary changes consist of polycythemia, somnolence, headache and right heart failure." | 1.24 | HYPOVENTILATION, CYANOSIS AND POLYCYTHEMIA IN A THIN MAN. ( DVORKIN, J; FRASER, RS; SPROULE, BJ, 1963) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 42 (73.68) | 18.7374 |
| 1990's | 8 (14.04) | 18.2507 |
| 2000's | 4 (7.02) | 29.6817 |
| 2010's | 3 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jun, JH | 1 |
| Kim, GS | 1 |
| Lee, JJ | 1 |
| Ko, JS | 1 |
| Kim, SJ | 1 |
| Jeon, PH | 1 |
| Ideno, S | 1 |
| Miyazawa, N | 1 |
| Ishikawa, S | 1 |
| Wakamiya, R | 1 |
| Shinto, A | 1 |
| Mikasa, H | 1 |
| Yamamoto, S | 1 |
| Mavridou, P | 1 |
| Dimitriou, V | 1 |
| Margaritis, A | 1 |
| Manataki, A | 1 |
| Cepeda, MS | 1 |
| Farrar, JT | 1 |
| Baumgarten, M | 1 |
| Boston, R | 1 |
| Carr, DB | 1 |
| Strom, BL | 1 |
| SURIANI, U | 1 |
| FERRARIO, L | 1 |
| PALMIERI, R | 1 |
| HERZKA, H | 1 |
| LIGHTOWLER, JE | 1 |
| SMITH, AE | 1 |
| FRASER, RS | 1 |
| SPROULE, BJ | 1 |
| DVORKIN, J | 1 |
| HERBERG, D | 1 |
| GEISLER, L | 1 |
| SCHENCK, P | 1 |
| IMPERATO, PJ | 1 |
| PALANCA, LM | 1 |
| FERNANDEZ, JP | 1 |
| LAMBERTSEN, CJ | 1 |
| WENDEL, H | 1 |
| Jain, S | 1 |
| Arya, VK | 1 |
| Gopalan, S | 1 |
| Jain, V | 1 |
| Daldrup, T | 1 |
| Lankisch, PG | 1 |
| Yaksh, TL | 1 |
| Brownridge, P | 1 |
| Wrobel, J | 1 |
| Watt-Smith, J | 1 |
| Jackson, C | 1 |
| Fong, M | 1 |
| Refstad, SO | 1 |
| Lindbaek, E | 1 |
| Huntington, KM | 1 |
| Boscoe, MJ | 1 |
| Wiener, PC | 2 |
| Wallace, S | 1 |
| Ong, B | 1 |
| Segstro, R | 1 |
| Au, AT | 1 |
| Henry, RJ | 1 |
| Pedersen, KE | 1 |
| Jones, DJ | 1 |
| Bösenberg, AT | 1 |
| Ratcliffe, S | 1 |
| Ehikhametalor, KO | 1 |
| Nelson, M | 1 |
| McCaffery, M | 1 |
| Hart, LL | 1 |
| Stephen, GW | 1 |
| Cooper, LV | 1 |
| Kalenda, Z | 1 |
| Kowlessar, OD | 1 |
| Iisalo, EU | 1 |
| Iisalo, E | 1 |
| Rosen, M | 2 |
| Hogg, M | 1 |
| Clark, RB | 1 |
| Beard, AG | 1 |
| Greifenstein, FE | 1 |
| Barclay, DL | 1 |
| McDowell, AJ | 1 |
| Whitlow, DR | 1 |
| Blaum, U | 1 |
| Schmidt, H | 1 |
| Pflüger, H | 1 |
| Brown, RS | 1 |
| Evans, JM | 1 |
| Hogg, MI | 1 |
| Greenfield, W | 2 |
| Sakamoto, E | 1 |
| Miller, R | 1 |
| Stratigos, GT | 1 |
| Arthur, A | 1 |
| Byrd, RB | 1 |
| Burns, JR | 1 |
| Daneshmend, TK | 1 |
| Bell, GD | 1 |
| Logan, RF | 1 |
| Raine, J | 1 |
| Warner, JO | 1 |
| Armstrong, PJ | 1 |
| Burgess, RW | 1 |
| Horch, R | 1 |
| Krönung, G | 1 |
| Westhofen, P | 1 |
| Giebel, GD | 1 |
| White, PF | 1 |
| Golub, MS | 1 |
| Eisele, JH | 1 |
| Kuhnert, BR | 1 |
| Cheun, JK | 1 |
| Krantz, T | 1 |
| Christensen, CB | 1 |
| Foldes, FF | 1 |
| Granada, MG | 1 |
| Beck, L | 1 |
| Clarke, RS | 1 |
| Dundee, JW | 1 |
| Carson, IW | 1 |
| Arora, MV | 1 |
| McCaughey, W | 1 |
| Frowein, RA | 1 |
| Karimi-Nejad, A | 1 |
| Dyrberg, V | 1 |
| Kolliker, K | 1 |
| Hamilton, WK | 1 |
| Moyers, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Quadratus Lumborum Block for Analgesia After Living Donor Kidney Transplantation: A Randomized Controlled Trial[NCT04908761] | 88 participants (Actual) | Interventional | 2021-06-03 | Completed | |||
| Personalizing Perioperative Morphine Analgesia for Adolescents Undergoing Major Spine Surgeries[NCT01839461] | 137 participants (Actual) | Observational | 2009-07-31 | Completed | |||
| Comparison of the Effect of a Single Shot Saphenous Block With Plain Bupivacaine vs. Protracted Bupivacaine Mixture as a Supplement to Continuous Sciatic Catheter After Major Ankle and Foot Surgery[NCT02346110] | Phase 4 | 40 participants (Actual) | Interventional | 2015-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for meperidine and Acute Hypercapnic Respiratory Failure
| Article | Year |
|---|---|
Spinal opiate analgesia: characteristics and principles of action.
Topics: Analgesia; Anesthesia; Animals; Autonomic Nervous System; Hemodynamics; Humans; Meperidine; Morphine | 1981 |
Neuroleptanesthesia for general surgery.
Topics: Alphaprodine; Anesthesia, Inhalation; Diphenhydramine; Droperidol; Female; Fentanyl; Humans; Hyperte | 1973 |
8 trials available for meperidine and Acute Hypercapnic Respiratory Failure
| Article | Year |
|---|---|
Analgesic efficacy of intramuscular opioids versus epidural analgesia in labor.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Cesarean Section; Female; Hu | 2003 |
Ventilatory depression of the newborn of women receiving pethidine or pentazocine. A double-blind comparative trial.
Topics: Anesthesia, Obstetrical; Apgar Score; Carbon Dioxide; Clinical Trials as Topic; Double-Blind Method; | 1980 |
The respiratory effects of tramadol in children under halothane an anaesthesia.
Topics: Analgesics, Opioid; Anesthesia, Inhalation; Anesthetics, Inhalation; Child; Child, Preschool; Crypto | 1998 |
Intrathecal pethidine as sole anaesthetic agent for operative procedures of the lower limb, inguinal area and perineum.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Lo | 2001 |
A comparison of high-dose pentazocine with pethidine and diazepam in paediatric premedication.
Topics: Child, Preschool; Clinical Trials as Topic; Diazepam; Double-Blind Method; Drug Evaluation; Female; | 1978 |
Naloxone in the parturient and her infant.
Topics: Adult; Apgar Score; Blood Gas Analysis; Clinical Trials as Topic; Drug Evaluation; Female; Fetal Blo | 1976 |
Reversal of narcotic depression in the neonate by nalozone.
Topics: Anesthesia, Obstetrical; Apgar Score; Carbon Dioxide; Female; Humans; Infant, Newborn; Infant, Newbo | 1976 |
Choice of incision and pain following gallbladder surgery.
Topics: Female; Gallbladder; Humans; Laparotomy; Length of Stay; Male; Meperidine; Middle Aged; Pain Measure | 1990 |
47 other studies available for meperidine and Acute Hypercapnic Respiratory Failure
| Article | Year |
|---|---|
Comparison of intrathecal morphine and surgical-site infusion of ropivacaine as adjuncts to intravenous patient-controlled analgesia in living-donor kidney transplant recipients.
Topics: Adult; Aged; Amides; Analgesia, Patient-Controlled; Analgesics, Opioid; Female; Fentanyl; Humans; In | 2017 |
[Anesthetic management of a patient with severe subcutaneous and mediastinal emphysema due to pertussis infection].
Topics: Airway Management; Anesthesia; Drainage; Extracorporeal Membrane Oxygenation; Female; Humans; Infant | 2014 |
Anesthesia for laparoscopic surgery in a patient with myotonic dystrophy (Steinert's disease): beneficial use of sugammadex, but incorrect use of pethidine: a case report.
Topics: Adult; Analgesics, Opioid; Androstanols; Anesthesia Recovery Period; Anesthesia, General; Cholecyste | 2011 |
Side effects of opioids during short-term administration: effect of age, gender, and race.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Analgesics, Opioid; Cohort Studies; Female; Fenta | 2003 |
Side effects of opioids during short-term administration: effect of age, gender, and race.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Analgesics, Opioid; Cohort Studies; Female; Fenta | 2003 |
Side effects of opioids during short-term administration: effect of age, gender, and race.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Analgesics, Opioid; Cohort Studies; Female; Fenta | 2003 |
Side effects of opioids during short-term administration: effect of age, gender, and race.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Analgesics, Opioid; Cohort Studies; Female; Fenta | 2003 |
[Effect of an allyl derivative of dromoran on respiratory depression induced by analgesics during protoxide and oxygen anesthesia].
Topics: Analgesics; Anesthesia; Cell Respiration; Humans; Meperidine; Morphine; Oxygen; Respiration; Respira | 1956 |
[Possibility of combating respiratory depression from analgesics during general anesthesia by the use of certain drugs].
Topics: Analgesics; Anesthesia; Anesthesia, General; Iatrogenic Disease; Meperidine; Morphine; Respiratory I | 1958 |
[The effect of amiphenazole (Daptazole) on the respiratory depression caused by pethidine].
Topics: Cell Respiration; Meperidine; Respiration; Respiratory Insufficiency; Thiazoles | 1961 |
BETA-(N-PYRROLIDYL)-BUTYROANILID (WS 10): ITS SUBACUTE TOXICITY, INFLUENCE ON MORPHINE ANALGESIA IN THE RAT AND MORPHINE ANALGESIA AND RESPIRATORY DEPRESSION IN THE RABBIT.
Topics: Analgesia; Analgesics; Analgesics, Non-Narcotic; Anilides; Antipyretics; Aspirin; Codeine; Meperidin | 1963 |
HYPOVENTILATION, CYANOSIS AND POLYCYTHEMIA IN A THIN MAN.
Topics: Cyanosis; Headache; Heart Failure; Humans; Hyperventilation; Hypoventilation; Male; Meperidine; Poly | 1963 |
[ON THE INFLUENCE OF SOME FREQUENTLY USED SEDATIVES AND ANALGESICS ON THE HUMAN RESPIRATORY CENTER WITH SPECIAL REFERENCE TO PATIENTS WITH ALVEOLAR HYPOVENTILATION].
Topics: Analgesics; Apnea; Humans; Hypnotics and Sedatives; Hypoventilation; Medulla Oblongata; Meperidine; | 1963 |
SUCCESSFUL TREATMENT WITH THE MUCOLYTIC AGENT ACETYLCYSTEINE.
Topics: Acetylcysteine; Arrhythmia, Sinus; Arrhythmias, Cardiac; Cysteine; Expectorants; Female; Kartagener | 1964 |
An alveolar carbon dioxide tension control system: its use to magnify respiratory depression by meperidine.
Topics: Carbon Dioxide; Cell Respiration; Humans; Meperidine; Respiration; Respiratory Insufficiency; Respir | 1960 |
A forensic toxicological dilemma: the interpretation of post-mortem concentrations of central acting analgesics.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Brain Chemistry; Diagnostic Errors; Drug Overdose; Fema | 2004 |
[Conservative treatment of acute pancreatitis].
Topics: Acetazolamide; Acute Disease; Acute Kidney Injury; Aftercare; Antacids; Aprotinin; Atropine; Bacteri | 1982 |
Respiratory depression following accidental subarachnoid pethidine.
Topics: Accidents; Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Female; Humans; Iatrogenic Disease; | 1983 |
Siphoning from a syringe pump: a cause of sudden overdose.
Topics: Aged; Cholecystectomy; Humans; Infusions, Parenteral; Male; Meperidine; Postoperative Care; Respirat | 1983 |
Iatrogenic collapse.
Topics: Drug Combinations; Humans; Meperidine; Respiratory Insufficiency | 1980 |
Iatrogenic collapse.
Topics: Adolescent; Female; Humans; Meperidine; Respiratory Insufficiency; Tidal Volume | 1980 |
Effects of naloxone on pethidine-induced neonatal depression.
Topics: Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Meperidine; Motor Activity; Naloxone; Re | 1980 |
Respiratory depression associated with meperidine spinal anaesthesia.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Spinal; Female; Hernia, Inguinal; Humans; Injections, Sp | 1994 |
Ethics: thanks for helping the learning process.
Topics: Ethics, Nursing; Humans; Male; Meperidine; Patient Advocacy; Respiratory Insufficiency | 1994 |
The influence of meperidine and nitrous oxide on respiratory depression in rats.
Topics: Analgesics, Opioid; Anesthetics, Inhalation; Animals; Blood Gas Analysis; Blood Pressure; Dose-Respo | 1997 |
Undertreatment of acute pain with narcotics.
Topics: Administration, Oral; Analgesics, Opioid; Codeine; Dose-Response Relationship, Drug; Drug Hypersensi | 1976 |
The role of analgesics in respiratory depression: a rabbit model.
Topics: Analgesics, Opioid; Animals; Animals, Newborn; Depression, Chemical; Fentanyl; Hypoxia; Meperidine; | 1977 |
Monitoring as anesthesia draws to a close.
Topics: Anesthesia; Blood Pressure; Carbon Dioxide; Cheyne-Stokes Respiration; Diffusion; Fentanyl; Heart Ar | 1979 |
Management of mild and severe alcoholic pancreatitis.
Topics: Alcoholism; Anesthesia, Epidural; Anti-Bacterial Agents; Glucagon; Humans; Intubation, Gastrointesti | 1975 |
Maternal pethidine and neonatal depression.
Topics: Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Meperidine; Nal | 1978 |
Reversible, titrated deep sedation for major office surgery.
Topics: Adolescent; Adult; Aged; Anesthesia, Local; Arrhythmias, Cardiac; Bradycardia; Humans; Hypotension; | 1977 |
[Anesthesia in pacemaker implantation. Experiences in 935 cases of anesthesia for the implantation or revision of a cardiac pacemaker].
Topics: Anesthesia, General; Arrhythmia, Sinus; Bradycardia; Halothane; Heart Arrest; Heart Block; Humans; H | 1977 |
Effects of pethidine on the newborn.
Topics: Humans; Infant, Newborn; Infant, Newborn, Diseases; Meperidine; Respiratory Insufficiency | 1976 |
Letter: Respiratory changes with diazepam.
Topics: Anesthesia, Dental; Carbon Dioxide; Diazepam; Humans; Meperidine; Oxygen; Partial Pressure; Respirat | 1975 |
Serious postextraction hemorrhage into the submandibular space: report of case.
Topics: Blood Pressure; Cheyne-Stokes Respiration; Female; Hematoma; Humans; Intubation, Intratracheal; Lido | 1975 |
Cough dynamics in the post-thoracotomy state.
Topics: Adult; Biopsy; Cough; Humans; Lung; Lung Volume Measurements; Male; Maximal Expiratory Flow Rate; Ma | 1975 |
Sedation for upper gastrointestinal endoscopy: results of a nationwide survey.
Topics: Benzodiazepines; Conscious Sedation; Endoscopy, Gastrointestinal; Heart Arrest; Humans; Hypoventilat | 1991 |
Fibreoptic bronchoscopy without general anaesthetic.
Topics: Adolescent; Adult; Anesthesia, Local; Bronchoscopes; Bronchoscopy; Child; Child, Preschool; Consciou | 1991 |
[The effect of lung diminishing interventions on immediate postoperative lung function and their modification by various forms of analgesia].
Topics: Adult; Aged; Airway Resistance; Analgesics; Buprenorphine; Carcinoma, Bronchogenic; Female; Humans; | 1990 |
Mishaps with patient-controlled analgesia.
Topics: Adult; Aged; Analgesia; Cesarean Section; Fentanyl; Hip Prosthesis; Humans; Infant; Meperidine; Post | 1987 |
Disposition of intrapartum narcotic analgesics in monkeys.
Topics: Alfentanil; Anesthesia, Intravenous; Anesthesia, Obstetrical; Animals; Female; Fentanyl; Fetal Blood | 1988 |
Intraspinal narcotic anesthesia in open heart surgery.
Topics: Anesthesia, Spinal; Cardiac Surgical Procedures; Humans; Meperidine; Morphine; Respiratory Insuffici | 1987 |
Respiratory depression after intrathecal opioids. Report of a patient receiving long-term epidural opioid therapy.
Topics: Dura Mater; Humans; Injections, Epidural; Male; Medication Errors; Meperidine; Middle Aged; Morphine | 1987 |
The use of a narcotic antagonist in the anesthetic management of the ambulatory oral surgery patient.
Topics: Anesthesia, Dental; Atropine; Carbon Dioxide; Catheterization; Diazepam; Female; Fentanyl; Humans; H | 1974 |
[Analgesia and anaesthesia during labour and delivery. (Symposion by letter) (author's transl)].
Topics: Acidosis, Respiratory; Analgesia; Anesthesia, Conduction; Anesthesia, Epidural; Anesthesia, Obstetri | 1973 |
Clinical studies of induction agents. XL. Althesin with various premedicants.
Topics: Anesthesia, Intravenous; Anesthetics; Atropine; Diazepam; Female; Humans; Hypotension; Ketones; Mepe | 1972 |
Multiple rib fractures. (Case P58).
Topics: Accidents, Traffic; Anesthesia, Conduction; Asthma; Bronchitis; Carbon Dioxide; Drainage; Humans; Hy | 1971 |
[Intensive therapy in craniocerebral injuries].
Topics: Adolescent; Adult; Aged; Brain Injuries; Child; Child, Preschool; Craniocerebral Trauma; Diazepam; H | 1969 |
A comparison of the effects of accumulated doses of pentazocine and pethidine on ventilation at PACO2=45mm Hg.
Topics: Carbon Dioxide; Humans; Injections, Intravenous; Male; Meperidine; Partial Pressure; Pentazocine; Re | 1971 |
Pneumothorax during surgery.
Topics: Blood Gas Analysis; Halothane; Humans; Laryngeal Neoplasms; Male; Meperidine; Middle Aged; Oxygen; P | 1966 |