meperidine and Ache
meperidine has been researched along with Ache in 441 studies
Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pain intensity was comparable in multiparous patients 20-30 minutes after administration of meperidine and nitrous oxide." | 9.69 | Meperidine Compared With Nitrous Oxide for Intrapartum Pain Relief in Multiparous Patients: A Randomized Controlled Trial. ( Dagilayske, D; Garmi, G; Inbar, S; Salim, R; Zafran, N; Zuarez-Easton, S, 2023) |
| "To compare the safety and efficacy of xylocaine gel and ketorolac as opioid-sparing analgesia compared with pethidine for shock wave lithotripsy (SWL) pain." | 9.30 | Efficacy of pethidine, ketorolac, and lidocaine gel as analgesics for pain control in shockwave lithotripsy: A single-blinded randomized controlled trial. ( Abol-Enein, H; Atwa, AM; El-Assmy, A; Elbaset, MA; Fadallah, M; Ghobrial, FK; Hashem, A; Laymon, M; Sheir, KZ, 2019) |
| "The results of our study showed that lidocaine puffs provided the best pain relief than the other analgesics used." | 9.20 | Effect of paracetamol, dexketoprofen trometamol, lidocaine spray, pethidine & diclofenac sodium application for pain relief during fractional curettage: A randomized controlled trial. ( Acmaz, G; Aksoy, H; Başer, M; Bayraktar, E; Müderris, İİ; Yilmaz, MO, 2015) |
| " Out of the 29 patients with more than one day of PCA, the median (range) of the Mean Pain Score was 44 (13-72) and 33 (3-89) in the morphine (n = 14) and pethidine (n = 15) groups, respectively (P = 0." | 9.15 | PCA analgesia for children with chemotherapy-related mucositis: a double-blind randomized comparison of morphine and pethidine. ( Allonier, C; Demirdjian, S; Hartmann, O; Iacobelli, S; Laplanche, A; Michon, J; Orbach, D; Oudot, C; Pagnier, A; Pein, F; Pichard-Leandri, E; Raimondo, G, 2011) |
| "Propofol, a commonly used anesthetic, often causes pain on injection." | 9.12 | Painless injection of propofol: pretreatment with ketamine vs thiopental, meperidine, and lidocaine. ( Boker, A; Ertok, E; Saadawy, I, 2007) |
| " The prevalence of nausea and vomiting was compared between morphine and meperidine." | 9.11 | Morphine induces less nausea than meperidine when administered parenterally. ( Allegra, J; Shih, RD; Silverman, ME, 2004) |
| "To determine the effectiveness and side effects of intravenous meperidine in labour pain relief." | 9.10 | Effectiveness of intravenous meperidine for pain relief in the first stage of labour. ( Komwilaisak, R; Somboonporn, W; Sookpanya, S; Soontrapa, S, 2002) |
| "At 30 and 60 min after drug administration, pain relief was greater in the pethidine group than in tramadol group." | 9.10 | Pethidine versus tramadol for pain relief during labor. ( Avsar, AF; Caglar, GS; Keskin, EA; Keskin, HL; Tabuk, M, 2003) |
| "9% saline (1 ml) on a double-blind basis, as pretreatment to reduce pain on injection of propofol." | 9.08 | Modification of pain on injection of propofol. A comparison of pethidine and lignocaine. ( Flynn, C; Lohan, D; Lyons, B; McCarroll, M, 1996) |
| "The analgesic and sedative effects of intravenous morphine or pethidine and their effect on anxiety were compared in a prospective, double-blind, randomised dose-response study." | 9.08 | Lack of analgesic effect of systemically administered morphine or pethidine on labour pain. ( Ekblom, A; Ekman-Ordeberg, G; Hjelm, A; Irestedt, L; Olofsson, C, 1996) |
| "To determine if a single dose of intramuscular ketorolac given on presentation to the emergency department has a narcotic-sparing effect in adult patients with sickle cell vaso-occlusive crisis pain." | 9.07 | Ketorolac for sickle cell vaso-occlusive crisis pain in the emergency department: lack of a narcotic-sparing effect. ( Mitchell, TR; Norris, RL; Wright, SW, 1992) |
| "A double-blind comparison of pethidine and meptazinol in the relief of pain during labour was undertaken in 205 healthy women." | 9.06 | Comparative study of meptazinol and pethidine for the relief of pain in labour. ( Sheikh, A; Tunstall, ME, 1986) |
| "The analgesic efficiency of ketamine and pethidine was compared in experimental ischemic pain and postoperative pain after oral surgery." | 9.06 | Comparison of ketamine and pethidine in experimental and postoperative pain. ( Hustveit, O; Maurset, A; Skoglund, LA; Øye, I, 1989) |
| "The effect of the opioid analgesics tramadol and pethidine on experimentally induced pain was investigated in a double blind study with healthy volunteers." | 7.67 | [Characterization of the effect of analgesics on the assessment of experimental pain in man. Pethidine and tramadol in a double-blind comparison]. ( Madler, C; Morawetz, RF; Parth, P, 1984) |
| "In a pain management program (200 patients), a group of daily users of oxycodone compound (29 patients) and a subgroup who were taking a "high dose" of oxycodone compound (13 patients) were compared with a group of 171 non-users of oxycodone compound." | 7.66 | Problems with the use of oxycodone compound in patients with chronic pain. ( Maruta, T; Swanson, DW, 1981) |
| "Meperidine analgesia was evident within 30 min of drug application, reaching a maximum after about 90 min." | 6.66 | Imipramine reduces experimental pain. ( Bromm, B; Meier, W; Scharein, E, 1986) |
| "The most important symptom in acute pancreatitis is pain." | 6.41 | [Meperidine (pethidine) outdated as analgesic in acute pancreatitis]. ( Helmers, JH; Otten, MH; Tjoeng, MM; van Voorthuizen, T, 2000) |
| "Pain intensity was comparable in multiparous patients 20-30 minutes after administration of meperidine and nitrous oxide." | 5.69 | Meperidine Compared With Nitrous Oxide for Intrapartum Pain Relief in Multiparous Patients: A Randomized Controlled Trial. ( Dagilayske, D; Garmi, G; Inbar, S; Salim, R; Zafran, N; Zuarez-Easton, S, 2023) |
| "The combination uses of midazolam and pethidine for sedation resulted in significant improvements in the pain, blood pressure, additional use of midazolam, and safety during bronchoscopy among patients." | 5.51 | Randomized single-blind comparative study of the midazolam/pethidine combination and midazolam alone during bronchoscopy. ( Furukawa, K; Hazama, D; Katsurada, M; Katsurada, N; Kiriu, T; Kobayashi, K; Mimura, C; Nagano, T; Nishimura, Y; Otoshi, T; Sato, H; Tachihara, M; Takata, N; Yamamoto, M; Yasuda, Y; Yoshioka, J; Yumura, M, 2022) |
| "To compare the safety and efficacy of xylocaine gel and ketorolac as opioid-sparing analgesia compared with pethidine for shock wave lithotripsy (SWL) pain." | 5.30 | Efficacy of pethidine, ketorolac, and lidocaine gel as analgesics for pain control in shockwave lithotripsy: A single-blinded randomized controlled trial. ( Abol-Enein, H; Atwa, AM; El-Assmy, A; Elbaset, MA; Fadallah, M; Ghobrial, FK; Hashem, A; Laymon, M; Sheir, KZ, 2019) |
| "Pain was controlled with long-term intravenous meperidine analgesia." | 5.29 | Prolonged parenteral meperidine analgesia during pregnancy for pain from an abdominal wall mesh graft. ( Aaen, V; Cowan, L; Sakala, EP; Small, ML, 1993) |
| "Pethidine with midazolam-induced conscious sedation for pain relief during transvaginal oocyte retrieval for in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) procedures is associated with residual pain and oversedation." | 5.20 | Patient-Controlled Remifentanil Analgesia as Alternative for Pethidine with Midazolam During Oocyte Retrieval in IVF/ICSI Procedures: A Randomized Controlled Trial. ( Boer, C; Douwenga, WM; Hompes, PG; Lier, MC; Mijatovic, V; Schats, R; Yilmaz, F, 2015) |
| "The results of our study showed that lidocaine puffs provided the best pain relief than the other analgesics used." | 5.20 | Effect of paracetamol, dexketoprofen trometamol, lidocaine spray, pethidine & diclofenac sodium application for pain relief during fractional curettage: A randomized controlled trial. ( Acmaz, G; Aksoy, H; Başer, M; Bayraktar, E; Müderris, İİ; Yilmaz, MO, 2015) |
| " Out of the 29 patients with more than one day of PCA, the median (range) of the Mean Pain Score was 44 (13-72) and 33 (3-89) in the morphine (n = 14) and pethidine (n = 15) groups, respectively (P = 0." | 5.15 | PCA analgesia for children with chemotherapy-related mucositis: a double-blind randomized comparison of morphine and pethidine. ( Allonier, C; Demirdjian, S; Hartmann, O; Iacobelli, S; Laplanche, A; Michon, J; Orbach, D; Oudot, C; Pagnier, A; Pein, F; Pichard-Leandri, E; Raimondo, G, 2011) |
| " Postoperative pain was treated with intravenous meperidine." | 5.14 | Electro-acupuncture for pain relief after nasal septoplasty: a randomized controlled study. ( Farbood, A; Ghafaripuor, S; Sahmeddini, MA, 2010) |
| "The mean pain scores for the three groups were: diclofenac and paracervical block 5." | 5.12 | A randomized comparison of different methods of analgesia in abortion using manual vacuum aspiration. ( López, JC; Ruiz, E; Vega-Malek, JC; Vergara, V; Vigil-De Gracia, P, 2007) |
| "Propofol, a commonly used anesthetic, often causes pain on injection." | 5.12 | Painless injection of propofol: pretreatment with ketamine vs thiopental, meperidine, and lidocaine. ( Boker, A; Ertok, E; Saadawy, I, 2007) |
| "Periprostatic lidocaine infiltration and/or intravenous synthetic opioid analgesics are not beneficial in significantly reducing pain during biopsy." | 5.11 | Periprostatic lidocaine infiltration and/or synthetic opioid (meperidine or tramadol) administration have no analgesic benefit during prostate biopsy. A prospective randomized double-blind placebo-controlled study comparing different methods. ( Akbay, E; Atici, S; Bozlu, M; Canpolat, B; Cayan, S; Oral, U; Schellhammer, PF; Ulusoy, E, 2004) |
| " The prevalence of nausea and vomiting was compared between morphine and meperidine." | 5.11 | Morphine induces less nausea than meperidine when administered parenterally. ( Allegra, J; Shih, RD; Silverman, ME, 2004) |
| " Patients in the PCS group had significantly higher pain scores and significantly more recall than those in the midazolam and pethidine group." | 5.10 | Patient-controlled sedation for colonoscopy: a randomized trial comparing patient-controlled administration of propofol and alfentanil with physician-administered midazolam and pethidine. ( Bright, E; Dalgleish, D; Elliott, J; Kimble, J; Roseveare, C; Shepherd, H, 2003) |
| "To determine the effectiveness and side effects of intravenous meperidine in labour pain relief." | 5.10 | Effectiveness of intravenous meperidine for pain relief in the first stage of labour. ( Komwilaisak, R; Somboonporn, W; Sookpanya, S; Soontrapa, S, 2002) |
| "The addition of a single bolus of meperidine to midazolam improves patient tolerance and lessens pain during colonoscopy without significantly increasing the frequency of side effects or prolonging recovery time." | 5.10 | Single bolus of midazolam versus bolus midazolam plus meperidine for colonoscopy: a prospective, randomized, double-blind trial. ( Imperiali, G; Lenoci, N; Mandelli, G; Meucci, G; Minoli, G; Radaelli, F; Spinzi, G; Strocchi, E; Terreni, N; Terruzzi, V, 2003) |
| "At 30 and 60 min after drug administration, pain relief was greater in the pethidine group than in tramadol group." | 5.10 | Pethidine versus tramadol for pain relief during labor. ( Avsar, AF; Caglar, GS; Keskin, EA; Keskin, HL; Tabuk, M, 2003) |
| " The patients who received bupivacaine at the trocar site clinically had less pain (p < 0." | 5.09 | Preinsertion local anesthesia at the trocar site improves perioperative pain and decreases costs of laparoscopic cholecystectomy. ( Faiz, H; Hasaniya, NW; Severino, R; Zayed, FF, 2001) |
| " pretreatment with fentanyl, morphine, meperidine, or lidocaine in reducing propofol injection pain." | 5.08 | The analgesic effect of fentanyl, morphine, meperidine, and lidocaine in the peripheral veins: a comparative study. ( Huang, S; Hwang, MH; Mok, MS; Pang, WW, 1998) |
| " This study was designed to: 1) compare the safety and efficacy of intravenous fentanyl, intravenous fentanyl combined with midazolam, and intramuscular meperidine-promethazine-chlorpromazine (MPC) compound when used for painful emergency department (ED) procedures: and 2) to determine whether the addition of et-CO2 monitoring enabled earlier identification of respiratory depression in this population." | 5.08 | The value of end-tidal CO2 monitoring when comparing three methods of conscious sedation for children undergoing painful procedures in the emergency department. ( Berns, SD; Boenning, DA; Hart, LS; Houck, CS, 1997) |
| " Patients in the PCA group self-administered varying doses of intravenous alfentanil according to their pain tolerance, while those in the control group were given a single bolus dose of 1 mg/kg body weight intravenous pethidine by the attending urologist before the start of the procedure." | 5.08 | Use of patient-controlled analgesia in extracorporeal shockwave lithotripsy. ( Chin, CM; Chng, HC; Lim, PH; NG, FC; Tay, KP, 1997) |
| " However, the benefit of the most often used combination of intravenous midazolam and pethidine on patient tolerance and pain and its cardiorespiratory risk have not been fully defined." | 5.08 | Sedation and analgesia for colonoscopy: patient tolerance, pain, and cardiorespiratory parameters. ( Fried, M; Froehlich, F; Gonvers, JJ; Hays, RD; Köhler, M; Preisig, M; Schwizer, W; Thorens, J, 1997) |
| "9% saline (1 ml) on a double-blind basis, as pretreatment to reduce pain on injection of propofol." | 5.08 | Modification of pain on injection of propofol. A comparison of pethidine and lignocaine. ( Flynn, C; Lohan, D; Lyons, B; McCarroll, M, 1996) |
| "The analgesic and sedative effects of intravenous morphine or pethidine and their effect on anxiety were compared in a prospective, double-blind, randomised dose-response study." | 5.08 | Lack of analgesic effect of systemically administered morphine or pethidine on labour pain. ( Ekblom, A; Ekman-Ordeberg, G; Hjelm, A; Irestedt, L; Olofsson, C, 1996) |
| " Acetaminophen and meperidine were given for postoperative pain." | 5.07 | Prophylactic antiemetic treatment with ondansetron in children undergoing tonsillectomy. ( Furst, SR; Rodarte, A, 1994) |
| "To determine if a single dose of intramuscular ketorolac given on presentation to the emergency department has a narcotic-sparing effect in adult patients with sickle cell vaso-occlusive crisis pain." | 5.07 | Ketorolac for sickle cell vaso-occlusive crisis pain in the emergency department: lack of a narcotic-sparing effect. ( Mitchell, TR; Norris, RL; Wright, SW, 1992) |
| "The analgesic efficiency of ketamine and pethidine was compared in experimental ischemic pain and postoperative pain after oral surgery." | 5.06 | Comparison of ketamine and pethidine in experimental and postoperative pain. ( Hustveit, O; Maurset, A; Skoglund, LA; Øye, I, 1989) |
| "A double-blind comparison of pethidine and meptazinol in the relief of pain during labour was undertaken in 205 healthy women." | 5.06 | Comparative study of meptazinol and pethidine for the relief of pain in labour. ( Sheikh, A; Tunstall, ME, 1986) |
| "The results of a controlled, double-blind clinical trial are reported demonstrating the potency of analgesia produced by orally and parenterally administered nefopam HCl in hospitalized patients with pain principally of skeletal and neuromuscular origin." | 5.04 | Controlled clinical trial of oral and parenteral nefopam hydrochloride. A novel and potent analgesic drug. ( Ballesteros, ML; Diamantopoulos, E; Gassel, MM; Hughes, AC; Petropoulos, V; Ré, ON, 1976) |
| "Some data suggest that meperidine may lead to a higher perioperative risk for delirium; however, high-quality studies that compare different opioids are lacking." | 4.95 | The Comparative Risk of Delirium with Different Opioids: A Systematic Review. ( de Rooij, SE; Spies, PE; Swart, LM; van der Zanden, V; van Munster, BC, 2017) |
| " We review the literature on intranasal administration of fentanyl, meperidine, diamorphine, and butorphanol to treat acute pain." | 4.83 | [Intranasal opioids for acute pain]. ( Añez Simón, C; Fuentes Baena, A; Rodríguez Pérez, A; Rull Bartomeu, M, 2006) |
| "Systemic labour pain treatment with opioids and inhaled nitrous oxide has for many decades frequently been used in medically developed countries." | 4.80 | Traditional analgesic agents: are parenteral narcotics passé and do inhalational agents still have a place in labour? ( Irestedt, L; Olofsson, C, 1998) |
| "Using an adjustable heart bar shoe model of equine foot pain, the objective of this study was to test the hypothesis that meperidine (pethidine) administered intramuscularly would prove more efficacious in alleviating lameness than a saline placebo." | 3.79 | Efficacy of intramuscular meperidine hydrochloride versus placebo in experimental foot lameness in horses. ( Foreman, JH; Ruemmler, R, 2013) |
| " While the analgesic activity was examined against thermally and chemically induced nociceptive pain in mice, using the acetic acid and hot-plate test methods." | 3.77 | Anti-inflammatory and analgesic activity of different extracts of Commiphora myrrha. ( Duan, JA; Hua, YQ; Qian, DW; Su, S; Tang, YP; Wang, T; Yu, L; Zhou, W, 2011) |
| "Pain management experts have recommended a diminished role for pethidine because of lack of superiority for any indication and greater potential for adverse effects compared with morphine." | 3.74 | Multifaceted education initiative minimizes pethidine prescribing in the emergency department. ( Braitberg, G; Lugt, J; Taylor, SE, 2007) |
| " Meperidine (Demerol [Abbott, Abbott Park, IL]) has been used for many years in the postoperative setting for pain control; however, in high doses, it has been associated with seizure." | 3.72 | Meperidine-induced seizure after revision hip arthroplasty. ( Beaulé, PE; Nguyen, VN; Smith, MI, 2004) |
| "Meperidine is FDA-approved for relieving moderate to severe pain and has been widely used since its introduction in the 1930s." | 3.71 | Removing meperidine from the health-system formulary--frequently asked questions. ( Beckwith, MC; Chandramouli, J; Fox, ER, 2002) |
| "To evaluate the proportion of drug abuse related to opioid analgesics and the trends in medical use and abuse of 5 opioid analgesics used to treat severe pain: fentanyl, hydromorphone, meperidine, morphine, and oxycodone." | 3.70 | Trends in medical use and abuse of opioid analgesics. ( Dahl, JL; Gilson, AM; Joranson, DE; Ryan, KM, 2000) |
| "Hyperalgesia and allodynia in 4 cancer patients treated with morphine disappeared after discontinuing or substituting morphine with other opioid agonists." | 3.69 | Disappearance of morphine-induced hyperalgesia after discontinuing or substituting morphine with other opioid agonists. ( Jensen, NH; Jensen, TS; Sjøgren, P, 1994) |
| "The effect of the opioid analgesics tramadol and pethidine on experimentally induced pain was investigated in a double blind study with healthy volunteers." | 3.67 | [Characterization of the effect of analgesics on the assessment of experimental pain in man. Pethidine and tramadol in a double-blind comparison]. ( Madler, C; Morawetz, RF; Parth, P, 1984) |
| " Twelve patients with pain secondary to cancer were simultaneously administered both morphine (10 mg) and pethidine (50 mg) in 10 ml of normal saline via an epidural catheter inserted in the lumbar region (usually L2,3) and attached to a subcutaneously implanted portal reservoir." | 3.67 | The influence of drug polarity on the absorption of opioid drugs into CSF and subsequent cephalad migration following lumbar epidural administration: application to morphine and pethidine. ( Armstrong, PJ; Cherry, DA; Cousins, MJ; Gourlay, GK; Plummer, JL, 1987) |
| "In a pain management program (200 patients), a group of daily users of oxycodone compound (29 patients) and a subgroup who were taking a "high dose" of oxycodone compound (13 patients) were compared with a group of 171 non-users of oxycodone compound." | 3.66 | Problems with the use of oxycodone compound in patients with chronic pain. ( Maruta, T; Swanson, DW, 1981) |
| "Effective analgesia resulted from the injection of peridural meperidine in two groups of cancer patients, eight with postoperative pain and eight with intractable pain." | 3.66 | Peridural meperidine in humans: analgesic response, pharmacokinetics, and transmission into CSF. ( Cousins, MJ; Glynn, CJ; Graham, JR; Mather, LE; Wilson, PR, 1981) |
| " (1) There is no cross-tolerance with opiates, and SCNS suppresses pain in patients under chronic meperidine medication." | 3.66 | Non-opioid pathways suppress pain in humans. ( Katz, RL; Walker, JB, 1981) |
| "Comparing bupivacaine's adjuvants in spinal anesthesia, we assessed the specific blocking characteristics and adverse effects of bupivacaine alone and in combination with dexmedetomidine or meperidine in spinal anesthesia during cesarean section." | 3.11 | Analgesic Characteristics of Bupivacaine Alone and in Combination with Dexmedetomidine or Meperidine in Spinal Anesthesia during Cesarean Section: A Double-Blind Randomized Clinical Trial Study. ( Azemati, S; Jouybar, R; Naderi-Boldaji, V; Zarghami, A, 2022) |
| "Ketorolac tromethamine is a well-tolerated, effective medication in the treatment of acute biliary colic." | 2.70 | Comparison of intravenous ketorolac and meperidine in the treatment of biliary colic. ( Henderson, SO; Newton, E; Swadron, S, 2002) |
| " Pethidine dosage by staff-controlled analgesia increased under study conditions, suggesting that mere pain-assessment and a 'competing' analgesic method motivated the BMT-unit staff to administer higher pethidine doses." | 2.69 | Patient-controlled versus staff-controlled analgesia with pethidine after allogeneic bone marrow transplantation. ( Flesche, CW; Germing, U; Heyll, A; Schröter, S; Willers, R; Wolf, HH; Zucker, TP, 1998) |
| "Meperidine was given in a similar manner as a bolus dose of 112." | 2.69 | Effects of tramadol and meperidine on respiration, plasma catecholamine concentrations, and hemodynamics. ( Kirvelä, OA; Leino, KA; Mildh, LH, 1999) |
| "None of these differences reached statistical significance." | 2.69 | Prophylactic metoclopramide is unnecessary with intravenous analgesia in the ED. ( Paoloni, R; Talbot-Stern, J, 2000) |
| "Pain was quantified by means of questionnaires completed by the patient and by her partner postoperatively." | 2.68 | A prospective randomized study comparing needles of different diameters for transvaginal ultrasound-directed follicle aspiration. ( Awonuga, A; Curson, R; Nargund, G; Oyesanya, O; Parsons, J; Waterstone, J, 1996) |
| "We investigated the per- and postoperative pain-reducing effect of pethidine given intra-articularly (i." | 2.67 | Is intra-articular pethidine an alternative to local anaesthetics in arthroscopy? A double-blind study comparing prilocaine with pethidine. ( Ekblom, A; Eriksson, E; Söderlund, A; Valentin, A; Westman, L, 1993) |
| "The duration of hypoxemia (transcutaneous partial pressure of O2 < 6." | 2.67 | Pain relief can reduce hypoxemia in distressed neonates during routine treatment procedures. ( Pokela, ML, 1994) |
| " Adverse events were monitored and documented." | 2.67 | Safety assessment of high-dose narcotic analgesia for emergency department procedures. ( Barsan, WG; Bartlett, R; Danzl, DF; Ling, LJ; Seger, D; Tomassoni, AJ, 1993) |
| "Meperidine analgesia was evident within 30 min of drug application, reaching a maximum after about 90 min." | 2.66 | Imipramine reduces experimental pain. ( Bromm, B; Meier, W; Scharein, E, 1986) |
| " (2) Since in the low frequency range the drugs exhibited contrary effects upon spontaneous and evoked EEG activity, the pre-/post-stimulus relationship of the delta power was found to be the most sensitive measure for monitoring the cerebral bioavailability of the tested drugs." | 2.66 | Pre-stimulus/post-stimulus relations in EEG spectra and their modulations by an opioid and an antidepressant. ( Bromm, B; Meier, W; Scharein, E, 1989) |
| " The dosage administered i." | 2.66 | A double-blind trial of the analgesic properties of physostigmine in postoperative patients. ( Gordh, TE; Hartvig, P; Petersson, J; Wiklund, L, 1986) |
| "The incidences of arrhythmias, lung oedema, hypotension and thromboembolic complications did not differ between the groups." | 2.65 | Analgesic treatment with levomepromazine in acute myocardial infarction. A randomized clinical trial. ( Davidsen, O; Lindeneg, O; Walsh, M, 1979) |
| "Vomiting was significantly more frequent in the placebo-treated group [0." | 2.64 | A controlled trial of antiemetics in abortion by PGF2alpha and laminaria. ( Federschneider, JM; Kaul, AF; Stubblefield, PG, 1978) |
| "The most important symptom in acute pancreatitis is pain." | 2.41 | [Meperidine (pethidine) outdated as analgesic in acute pancreatitis]. ( Helmers, JH; Otten, MH; Tjoeng, MM; van Voorthuizen, T, 2000) |
| "Pain is therefore a critical aspect of hemophilia." | 1.72 | Comparison of analgesic consumption of hemophilic and non-hemophilic patients in knee arthroplasty. ( Buget, MI; Canbolat, N; Dinç, T; Kılıçoğlu, Öİ; Koç, B; Koltka, K; Zulfikar, B, 2022) |
| "Although pain was significantly associated with greater selected opioids use (OR=3." | 1.51 | Patterns of opioid use (codeine, morphine or meperidine) in the Canadian population over time: analysis of the Longitudinal National Population Health Survey 1994-2011. ( Badley, EM; Canizares, M; Power, JD; Rampersaud, YR, 2019) |
| "Meperidine was applied to animals with increasing doses and their tail flick latencies (TFL) were noted at 20, 40, 60, 90, 120, 180, and 240 min." | 1.43 | Combination of paracetamol or ketamine with meperidine enhances antinociception. ( Akkar, OB; Cetin, A; Cetin, M; Gulturk, S; Kula, A, 2016) |
| "Pain was associated with younger age (p < 0." | 1.38 | The burden of endoscopic retrograde cholangiopancreatography (ERCP) performed with the patient under conscious sedation. ( Jeurnink, SM; Kuipers, E; Siersema, P; Steyerberg, E, 2012) |
| "We implemented guidelines for treatment of pain in our emergency department (ED) and tracked the major analgesics used in this ED to monitor trends in pain management over a decade." | 1.36 | Tracking the effects of policy changes in prescribing analgesics in one emergency department: a 10-year analysis. ( Brill, S; Halpern, P; Hertz, D; Meissner, W; Or, J; Zaslansky, R, 2010) |
| "Pain was the most common complication, although use of analgesia after 2 hours of observation was low." | 1.35 | Post-procedure surveillance in liver biopsy: how long is long enough? ( Basford, P; Bell, M; Derrett, S; Howard, R; Karageorge, G; Schultz, M; van Harselaar, K, 2008) |
| "Morphine is a preferred narcotic since meperidine forms toxic metabolites." | 1.32 | Determinants of prescribing meperidine compared to morphine in hospitalized patients. ( Desbiens, N; Doshi, N; Panda, M; Sheldon, S, 2004) |
| "Fentanyl has a 7 gram usage versus a 100 gram INCB allocation." | 1.31 | Opioid use in chronic pain management in the Philippines. ( Espinosa, EL; Harder, SM; Javier, FO; Magpantay, LA; Unite, MA, 2001) |
| "Meperidine is a widely prescribed opioid analgesic used in a variety of clinical situations." | 1.30 | Meperidine-induced generalized seizures with normal renal function. ( Marinella, MA, 1997) |
| "Meperidine also was administered to patients in renal failure or with medications contraindicated with meperidine use." | 1.30 | Meperidine utilization and compliance with Agency for Health Care Policy and Research guidelines in a tertiary care hospital. ( Faut-Callahan, M; Paice, J; Pellegrini, JE, 1999) |
| "Pain was controlled with long-term intravenous meperidine analgesia." | 1.29 | Prolonged parenteral meperidine analgesia during pregnancy for pain from an abdominal wall mesh graft. ( Aaen, V; Cowan, L; Sakala, EP; Small, ML, 1993) |
| " The A50 (dose producing 50% MPE) for each drug or drug combination was determined from the dose-response curve." | 1.28 | Antinociceptive interaction between opioids and medetomidine: systemic additivity and spinal synergy. ( Bagley, J; Harris, S; Lin, BS; Lloyd, P; Messineo, E; Ossipov, MH, 1990) |
| "Nine patients with primary fibromyalgia participated." | 1.28 | Diagnostic epidural opioid blockade in primary fibromyalgia at rest and during exercise. ( Bengtsson, A; Bengtsson, M; Jorfeldt, L, 1989) |
| "The gene for sickle cell disease is carried by 8% of the African-American population in the United States." | 1.28 | Sickle cell vaso-occlusive pain crisis in adults: alternative strategies for management in the emergency department. ( Pollack, CV; Sanders, DY; Severance, HW, 1992) |
| "Continuous Reaction Time (CRT) was measured in cancer patients receiving peripherally acting analgesics either alone (n = 16) or in combination with opioids (n = 16)." | 1.28 | Reaction time in cancer patients receiving peripherally acting analgesics alone or in combination with opioids. ( Banning, A; Kaiser, F; Sjøgren, P, 1992) |
| " Patients given continuous infusions required more narcotic to control their pain and had more side effects than those treated with bolus injections alone, suggesting a dose-response relationship between narcotic dose and several known side effects." | 1.27 | Intravenous narcotic therapy for children with severe sickle cell pain crisis. ( Buchanan, GR; Cole, TB; Smith, SJ; Sprinkle, RH, 1986) |
| "Colic was produced by inflating a balloon in the horses' cecum." | 1.27 | Visceral analgesia: effects of xylazine, butorphanol, meperidine, and pentazocine in horses. ( Muir, WW; Robertson, JT, 1985) |
| "Pain was estimated by subjective bioassay." | 1.26 | Relationship between blood meperidine concentrations and analgesic response: a preliminary report. ( Austin, KL; Mather, LE; Stapleton, JV, 1980) |
| "Thirteen patients with hypersplenism were successfully treated with transcatheter partial embolization of their spleen." | 1.26 | Partial splenic embolization in the treatment of hypersplenism. ( Capek, V; Jonasson, O; Mozes, M; Spigos, DG, 1979) |
| "Early detection and treatment of drug abuse should minimize some of the difficulties involved in management of treatment-resistive patients with chronic pain." | 1.26 | Drug abuse and dependency in patients with chronic pain. ( Finlayson, RE; Maruta, T; Swanson, DW, 1979) |
| "Xylazine was significantly more effective in obtunding deep pain (P less than 0." | 1.26 | Objective tests of analgesic drugs in ponies. ( Lumb, WV; Pippi, NL, 1979) |
| " Demerol in small dosage is safe and effective." | 1.23 | An evaluation of obstetrical analgesia. ( FIST, HS, 1954) |
Research
Studies (441)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 239 (54.20) | 18.7374 |
| 1990's | 82 (18.59) | 18.2507 |
| 2000's | 78 (17.69) | 29.6817 |
| 2010's | 35 (7.94) | 24.3611 |
| 2020's | 7 (1.59) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Katsurada, M | 1 |
| Tachihara, M | 1 |
| Katsurada, N | 1 |
| Takata, N | 1 |
| Sato, H | 1 |
| Mimura, C | 1 |
| Yoshioka, J | 1 |
| Furukawa, K | 1 |
| Yumura, M | 1 |
| Otoshi, T | 1 |
| Yasuda, Y | 1 |
| Kiriu, T | 1 |
| Hazama, D | 1 |
| Nagano, T | 1 |
| Yamamoto, M | 1 |
| Nishimura, Y | 1 |
| Kobayashi, K | 2 |
| Wang, JJ | 1 |
| Teng, SF | 1 |
| Chu, YR | 1 |
| Chu, CC | 1 |
| Ho, CH | 1 |
| Chu, LL | 1 |
| Azemati, S | 1 |
| Zarghami, A | 1 |
| Jouybar, R | 1 |
| Naderi-Boldaji, V | 1 |
| Canbolat, N | 1 |
| Dinç, T | 1 |
| Koltka, K | 1 |
| Zulfikar, B | 1 |
| Koç, B | 1 |
| Kılıçoğlu, Öİ | 1 |
| Buget, MI | 1 |
| Zuarez-Easton, S | 1 |
| Zafran, N | 1 |
| Garmi, G | 1 |
| Dagilayske, D | 1 |
| Inbar, S | 1 |
| Salim, R | 1 |
| Arslan, Z | 1 |
| Kartufan, FF | 1 |
| Kuloglu Genc, M | 1 |
| Battal, D | 1 |
| Yayla, M | 1 |
| Turkmen, Z | 1 |
| Boyle, JM | 1 |
| McCall, KL | 1 |
| Nichols, SD | 1 |
| Piper, BJ | 1 |
| Swart, LM | 1 |
| van der Zanden, V | 1 |
| Spies, PE | 1 |
| de Rooij, SE | 1 |
| van Munster, BC | 1 |
| Carter, C | 1 |
| Viveash, S | 1 |
| Kranke, P | 1 |
| Weibel, S | 1 |
| Bosetti, C | 1 |
| Santucci, C | 1 |
| Radrezza, S | 1 |
| Erthal, J | 1 |
| Berterame, S | 1 |
| Corli, O | 1 |
| Melber, AA | 1 |
| Hashem, A | 1 |
| Ghobrial, FK | 1 |
| Elbaset, MA | 1 |
| Atwa, AM | 1 |
| Fadallah, M | 1 |
| Laymon, M | 1 |
| El-Assmy, A | 1 |
| Sheir, KZ | 1 |
| Abol-Enein, H | 1 |
| Canizares, M | 1 |
| Power, JD | 1 |
| Rampersaud, YR | 1 |
| Badley, EM | 1 |
| Holme, Ø | 1 |
| Moritz, V | 1 |
| Bretthauer, M | 1 |
| Seip, B | 1 |
| Glomsaker, T | 1 |
| de Lange, T | 1 |
| Aabakken, L | 1 |
| Stallemo, A | 1 |
| Høie, O | 1 |
| Dahler, S | 1 |
| Sandvei, PK | 1 |
| Stray, N | 1 |
| Ystrøm, CM | 1 |
| Hoff, G | 1 |
| Jelsness-Jørgensen, LP | 1 |
| Lerang, F | 1 |
| Sandvei, P | 1 |
| Søberg, T | 1 |
| Henriksen, M | 1 |
| Ritwik, P | 1 |
| Cao, LT | 1 |
| Curran, R | 1 |
| Musselman, RJ | 1 |
| Foreman, JH | 1 |
| Ruemmler, R | 1 |
| Lier, MC | 1 |
| Douwenga, WM | 1 |
| Yilmaz, F | 2 |
| Schats, R | 1 |
| Hompes, PG | 1 |
| Boer, C | 1 |
| Mijatovic, V | 1 |
| Xu, N | 1 |
| Xue, XY | 1 |
| Li, XD | 1 |
| Wei, Y | 1 |
| Lin, N | 1 |
| Hsieh, YH | 1 |
| Koo, M | 1 |
| Leung, FW | 1 |
| Hong, MJ | 1 |
| Sung, IK | 1 |
| Lee, SP | 1 |
| Cheon, BK | 1 |
| Kang, H | 1 |
| Kim, TY | 1 |
| Pan, A | 1 |
| Alansari, M | 1 |
| Lubcke, R | 1 |
| Schlup, M | 1 |
| Williams, M | 1 |
| Fraser, M | 1 |
| Buckingham, S | 1 |
| Schultz, M | 2 |
| Kula, A | 1 |
| Akkar, OB | 1 |
| Gulturk, S | 1 |
| Cetin, M | 1 |
| Cetin, A | 1 |
| Cheng, YJ | 1 |
| Mittal, P | 1 |
| Goyal, M | 1 |
| Acmaz, G | 1 |
| Bayraktar, E | 1 |
| Aksoy, H | 1 |
| Başer, M | 1 |
| Yilmaz, MO | 1 |
| Müderris, İİ | 1 |
| Dewitt, J | 1 |
| McGreevy, K | 1 |
| Sherman, S | 1 |
| Imperiale, TF | 2 |
| Maximov, A | 1 |
| Howard, R | 1 |
| Karageorge, G | 1 |
| van Harselaar, K | 1 |
| Bell, M | 1 |
| Basford, P | 1 |
| Derrett, S | 1 |
| JACK, WW | 1 |
| TAYLOR, ES | 1 |
| Millette, VM | 1 |
| Steagall, PV | 1 |
| Duke-Novakovski, T | 1 |
| Livingston, AJ | 1 |
| Phillips, WJ | 1 |
| Jones, J | 1 |
| McCarter, J | 1 |
| Meng, P | 1 |
| Wang, LL | 1 |
| Hassan, HE | 1 |
| Mercer, SL | 1 |
| Cunningham, CW | 1 |
| Coop, A | 1 |
| Eddington, ND | 1 |
| Zaslansky, R | 1 |
| Hertz, D | 1 |
| Brill, S | 1 |
| Or, J | 1 |
| Meissner, W | 1 |
| Halpern, P | 1 |
| Chaou, CH | 1 |
| Chen, CK | 1 |
| Chen, JC | 1 |
| Chiu, TF | 1 |
| Lin, CC | 1 |
| Sahmeddini, MA | 1 |
| Farbood, A | 1 |
| Ghafaripuor, S | 1 |
| Dobbins, EH | 1 |
| Cinar, K | 1 |
| Yakut, M | 1 |
| Ozden, A | 1 |
| Fontein, Y | 1 |
| Villanueva-Pérez, VL | 1 |
| Asensio-Samper, JM | 1 |
| Fabregat-Cid, G | 1 |
| Carmen, MR | 1 |
| de Andrés-Ibáñez, JA | 1 |
| TAYLOE, JC | 1 |
| HALL, JE | 1 |
| Uzun, B | 1 |
| Kekec, Z | 1 |
| Gurkan, E | 1 |
| Wambugu, SN | 1 |
| Towett, PK | 1 |
| Kiama, SG | 1 |
| Abelson, KS | 1 |
| Kanui, TI | 1 |
| Jakobovits, A | 1 |
| FLATT, WD | 1 |
| Su, S | 1 |
| Wang, T | 1 |
| Duan, JA | 1 |
| Zhou, W | 1 |
| Hua, YQ | 1 |
| Tang, YP | 1 |
| Yu, L | 1 |
| Qian, DW | 1 |
| Oudot, C | 1 |
| Laplanche, A | 1 |
| Orbach, D | 1 |
| Pein, F | 1 |
| Michon, J | 1 |
| Raimondo, G | 1 |
| Pichard-Leandri, E | 1 |
| Allonier, C | 1 |
| Iacobelli, S | 1 |
| Pagnier, A | 1 |
| Demirdjian, S | 1 |
| Hartmann, O | 1 |
| Kim, MH | 1 |
| Park, H | 1 |
| Park, EC | 1 |
| Park, K | 1 |
| Alatise, OI | 1 |
| Agbakwuru, AE | 1 |
| Takure, AO | 1 |
| Adisa, AO | 1 |
| Akinkuolie, AA | 1 |
| Jeurnink, SM | 1 |
| Steyerberg, E | 1 |
| Kuipers, E | 1 |
| Siersema, P | 1 |
| Gallego Vilar, D | 1 |
| García Fadrique, G | 1 |
| Di Capua Sacoto, C | 1 |
| Beltran Persiva, J | 1 |
| Perez Mestre, M | 1 |
| De Francia, JA | 1 |
| Povo Martin, I | 1 |
| Miralles Aguado, J | 1 |
| Garau Perelló, C | 1 |
| Sanchis Verdu, L | 1 |
| Gallego Gomez, J | 1 |
| Sakalidis, VS | 1 |
| Williams, TM | 1 |
| Hepworth, AR | 1 |
| Garbin, CP | 1 |
| Hartmann, PE | 1 |
| Paech, MJ | 2 |
| Al-Tamimi, Y | 1 |
| Geddes, DT | 1 |
| Lok, IH | 1 |
| Chan, MT | 1 |
| Chan, DL | 1 |
| Cheung, LP | 1 |
| Haines, CJ | 1 |
| Yuen, PM | 1 |
| Ury, WA | 1 |
| Rahn, M | 1 |
| Tolentino, V | 1 |
| Pignotti, MG | 1 |
| Yoon, J | 1 |
| McKegney, P | 1 |
| Sulmasy, DP | 1 |
| Christiansen, P | 1 |
| Klostergaard, KM | 1 |
| Terp, MR | 1 |
| Poulsen, C | 1 |
| Agger, AO | 1 |
| Rasmussen, KL | 1 |
| Henderson, SO | 1 |
| Swadron, S | 1 |
| Newton, E | 1 |
| Soontrapa, S | 1 |
| Somboonporn, W | 1 |
| Komwilaisak, R | 1 |
| Sookpanya, S | 1 |
| van Wilgenburg, H | 1 |
| van Schaick Zillesen, PG | 1 |
| Krulichova, I | 1 |
| Radaelli, F | 1 |
| Meucci, G | 1 |
| Terruzzi, V | 1 |
| Spinzi, G | 1 |
| Imperiali, G | 1 |
| Strocchi, E | 1 |
| Lenoci, N | 1 |
| Terreni, N | 1 |
| Mandelli, G | 1 |
| Minoli, G | 1 |
| Lázaro, C | 1 |
| Caseras, X | 1 |
| Torrubia, R | 1 |
| Baños, JE | 1 |
| Keskin, HL | 1 |
| Keskin, EA | 1 |
| Avsar, AF | 1 |
| Tabuk, M | 1 |
| Caglar, GS | 1 |
| Bright, E | 1 |
| Roseveare, C | 1 |
| Dalgleish, D | 1 |
| Kimble, J | 1 |
| Elliott, J | 1 |
| Shepherd, H | 1 |
| ARMAND, MF | 1 |
| CIMOCH, PJ | 1 |
| WIRTS, CW | 1 |
| FORTI, D | 1 |
| FIST, HS | 1 |
| LASAGNA, L | 1 |
| BEECHER, HK | 1 |
| FAUCETT, RL | 2 |
| KLEIN, MR | 1 |
| DELEGUE, L | 1 |
| FOLDES, FF | 2 |
| ERGIN, KH | 1 |
| MARGOLIUS, BR | 1 |
| KEPES, ER | 1 |
| TOWNES, CD | 1 |
| MANN, SH | 1 |
| SAHAGIAN-EDWARDS, A | 1 |
| EGBERT, LD | 1 |
| NORTON, ML | 1 |
| ECKENHOFF, JE | 1 |
| DRIPPS, RD | 1 |
| GREEN, AF | 1 |
| McNALL, PG | 1 |
| KOUKAL, LR | 1 |
| TANAKA, R | 1 |
| BONO, F | 1 |
| GAZZANIGA, M | 1 |
| DUNDEE, JW | 5 |
| MOORE, J | 1 |
| RATELLE, AE | 1 |
| KIM, MK | 1 |
| CRANIN, AN | 1 |
| CRANIN, SL | 1 |
| GORDON, EJ | 1 |
| TABOR, GL | 1 |
| LAJOIE, WJ | 1 |
| CHARPENTIER, J | 2 |
| LIGHTOWLER, JE | 1 |
| SMITH, AE | 1 |
| SAUR, HT | 1 |
| COENEN, W | 1 |
| STEINHAUS, JE | 1 |
| LEE, WJ | 1 |
| OPDERBECKE, HW | 1 |
| TSCHERNE, G | 1 |
| CASS, LJ | 1 |
| FREDERIK, WS | 1 |
| REHN, J | 1 |
| HARRFELDT, HP | 1 |
| MATTS, SG | 2 |
| ARGENT, DE | 1 |
| WANG, RI | 1 |
| CHERNISH, SM | 1 |
| GRUBER, C | 1 |
| CHHUTTANI, PN | 1 |
| ANAND, SS | 1 |
| JYOTI, SP | 1 |
| RAI, S | 1 |
| CHITKARA, NL | 1 |
| BARNES, JH | 1 |
| MANNARELLI, AA | 1 |
| ERVIN, FR | 2 |
| MARK, VH | 1 |
| GUZMAN, F | 2 |
| BRAUN, C | 2 |
| LIM, RK | 2 |
| POTTER, GD | 1 |
| RODGERS, DW | 2 |
| ULLERY, JC | 1 |
| KAH, R | 1 |
| COTTINGHAM, JW | 1 |
| SCHWARTZ, JI | 1 |
| WEISIGER, BB | 1 |
| HARTLEY, J | 1 |
| SHAPERO, M | 1 |
| WILSON, C | 1 |
| PENA, EF | 1 |
| GOTO, K | 1 |
| DICKERSON, GD | 1 |
| ENGLE, RJ | 1 |
| BOLDINO, G | 1 |
| HOFF, HR | 1 |
| HOTZ, MM | 1 |
| SPERBER, RJ | 1 |
| FISCH, S | 1 |
| DEGRAFF, AC | 1 |
| SIMONS, E | 1 |
| BATIREREGA, LV | 1 |
| VILIUA, J | 1 |
| WHIMSTER, WF | 1 |
| SADOVE, MS | 1 |
| BALAGOT, RC | 1 |
| BLAIR, AE | 1 |
| HORAKOVA, Z | 1 |
| VOTAVA, Z | 1 |
| JEPSEN, O | 2 |
| KRISTIANSEN, F | 2 |
| LEWIS, RF | 1 |
| MASSON, AH | 1 |
| Beckwith, MC | 1 |
| Fox, ER | 1 |
| Chandramouli, J | 1 |
| Weinman, BP | 1 |
| Stanwell-Smith, R | 1 |
| ROSENFELD, SS | 1 |
| LAPAN, B | 1 |
| WEINSTEIN, MS | 1 |
| Parker, M | 1 |
| Bozlu, M | 1 |
| Atici, S | 1 |
| Ulusoy, E | 1 |
| Canpolat, B | 1 |
| Cayan, S | 1 |
| Akbay, E | 1 |
| Schellhammer, PF | 2 |
| Oral, U | 1 |
| Stevenson, JG | 1 |
| Pearlman, M | 1 |
| Green, CR | 1 |
| Newland, S | 1 |
| Grondin, L | 1 |
| Thompson, M | 1 |
| Golembiewski, J | 2 |
| Campbell, D | 1 |
| Beaulé, PE | 1 |
| Smith, MI | 1 |
| Nguyen, VN | 1 |
| Tsui, MH | 1 |
| Ngan Kee, WD | 2 |
| Ng, FF | 1 |
| Lau, TK | 1 |
| Panda, M | 1 |
| Desbiens, N | 1 |
| Doshi, N | 1 |
| Sheldon, S | 1 |
| Silverman, ME | 1 |
| Shih, RD | 1 |
| Allegra, J | 1 |
| Perlman, KM | 1 |
| Myers-Phariss, S | 1 |
| Rhodes, JC | 1 |
| Little, M | 1 |
| Hansen, GR | 1 |
| Bledsoe, B | 1 |
| Braude, D | 1 |
| Dailey, MW | 1 |
| Myers, J | 1 |
| Richards, M | 1 |
| Wesley, K | 1 |
| Gupta, RK | 1 |
| Tandon, VR | 1 |
| Basaranoglu, G | 1 |
| Erden, V | 1 |
| Delatioglu, H | 1 |
| Saitoglu, L | 1 |
| Pielage, P | 1 |
| Shipton, E | 1 |
| Becker, DE | 1 |
| Phero, JC | 1 |
| Adams, SM | 1 |
| Charles, KS | 1 |
| Osagie, K | 1 |
| Battini, RK | 1 |
| Vranken, JH | 1 |
| van Kan, HJ | 1 |
| van der Vegt, MH | 1 |
| Wan Hazmy, CH | 1 |
| Maizuliana, SH | 1 |
| Mastura, MT | 1 |
| Norazlina, M | 1 |
| Añez Simón, C | 1 |
| Rull Bartomeu, M | 1 |
| Rodríguez Pérez, A | 1 |
| Fuentes Baena, A | 1 |
| Taylor, SE | 1 |
| Braitberg, G | 1 |
| Lugt, J | 1 |
| Raymo, LL | 1 |
| Camejo, M | 1 |
| Fudin, J | 1 |
| López, JC | 1 |
| Vigil-De Gracia, P | 1 |
| Vega-Malek, JC | 1 |
| Ruiz, E | 1 |
| Vergara, V | 1 |
| Ahmed, A | 1 |
| Abbasi, S | 1 |
| Prakash, C | 1 |
| Chandar, S | 1 |
| Elbourne, D | 3 |
| Wiseman, RA | 2 |
| Fu, CY | 1 |
| Tang, XL | 1 |
| Yang, Q | 1 |
| Chen, Q | 1 |
| Wang, R | 1 |
| Derossi, R | 1 |
| Medeiros, U | 1 |
| de Almeida, RG | 1 |
| Righetto, FR | 1 |
| Frazílio, FO | 1 |
| Mazdak, H | 1 |
| Abazari, P | 1 |
| Ghassami, F | 1 |
| Najafipour, S | 1 |
| Saadawy, I | 1 |
| Ertok, E | 1 |
| Boker, A | 1 |
| Karaaslan, K | 1 |
| Gulcu, N | 1 |
| Yigit, B | 1 |
| Kocoglu, H | 1 |
| MOORMAN, VR | 1 |
| BIRENBOIM, IM | 1 |
| Morgan, MT | 1 |
| Howland, MA | 1 |
| Goldfrank, LR | 1 |
| Ballas, SK | 1 |
| Hopton, DS | 1 |
| Torrance, HB | 1 |
| Hamilton, RC | 1 |
| Clarke, RS | 1 |
| Loan, WB | 2 |
| Morrison, JD | 2 |
| Tamsen, A | 1 |
| Hartvig, P | 2 |
| Dahlström, B | 1 |
| Wahlström, A | 1 |
| Terenius, L | 1 |
| Yaksh, TL | 3 |
| Reddy, SV | 1 |
| Akintonwa, A | 1 |
| Claiborne, R | 1 |
| Foley, KM | 1 |
| Fuller, RK | 1 |
| Loveland, JP | 1 |
| Frankel, MH | 1 |
| Stambaugh, JE | 1 |
| Lane, C | 1 |
| Walker, JB | 1 |
| Katz, RL | 1 |
| Thomas, TA | 1 |
| Fletcher, JE | 1 |
| Hill, RG | 1 |
| Gebhart, GF | 1 |
| Lorens, SA | 1 |
| Parth, P | 1 |
| Madler, C | 1 |
| Morawetz, RF | 1 |
| Benad, G | 1 |
| Alreja, M | 1 |
| Mutalik, P | 1 |
| Nayar, U | 1 |
| Manchanda, SK | 1 |
| Bromm, B | 4 |
| Meier, W | 3 |
| Imbeloni, LE | 1 |
| Joehl, RJ | 1 |
| Koch, KL | 1 |
| Nahrwold, DL | 1 |
| Todd, B | 1 |
| Morse, RH | 1 |
| Mätzsch, T | 1 |
| Holmlund, D | 1 |
| Larsen, JJ | 1 |
| Christensen, AV | 1 |
| Kaiko, RF | 1 |
| Wallenstein, SL | 1 |
| Rogers, A | 1 |
| Grabinski, P | 1 |
| Houde, RW | 1 |
| Harper, NJ | 1 |
| Thomson, J | 1 |
| Brayshaw, SA | 1 |
| Wright, JT | 1 |
| Robinson, JO | 3 |
| Rosen, M | 4 |
| Evans, JM | 2 |
| Revill, SI | 3 |
| David, H | 2 |
| Rees, GA | 2 |
| Nel, CP | 1 |
| Bloch, B | 1 |
| Rush, JM | 1 |
| Fishburne, JI | 2 |
| Hodgkinson, R | 1 |
| Husain, FJ | 1 |
| Tung, AS | 1 |
| Meffert, H | 1 |
| Glynn, CJ | 1 |
| Mather, LE | 3 |
| Cousins, MJ | 2 |
| Graham, JR | 1 |
| Wilson, PR | 1 |
| Müller, H | 2 |
| Börner, U | 1 |
| Stoyanov, M | 1 |
| Gleumes, L | 1 |
| Hempelmann, G | 1 |
| Maruta, T | 2 |
| Swanson, DW | 2 |
| Sastry, BR | 1 |
| Austin, KL | 1 |
| Stapleton, JV | 1 |
| Goucke, CR | 1 |
| Graziotti, PJ | 1 |
| Luczak, J | 1 |
| Muehlenberg, K | 1 |
| Nauck, F | 1 |
| Giannina, G | 1 |
| Guzman, ER | 1 |
| Lai, YL | 1 |
| Lake, MF | 1 |
| Cernadas, M | 1 |
| Vintzileos, AM | 1 |
| Nissen, E | 1 |
| Lilja, G | 1 |
| Matthiesen, AS | 1 |
| Ransjö-Arvidsson, AB | 1 |
| Uvnäs-Moberg, K | 1 |
| Widström, AM | 1 |
| DiPalma, JA | 1 |
| Herrera, JL | 1 |
| Weis, FR | 1 |
| Dark-Mezick, DL | 1 |
| Brown, RS | 1 |
| Strauss, A | 1 |
| Sjøgren, P | 2 |
| Jensen, NH | 2 |
| Jensen, TS | 1 |
| Furst, SR | 1 |
| Rodarte, A | 1 |
| Dawson, C | 1 |
| Vale, JA | 1 |
| Corry, DA | 1 |
| Cohen, NP | 1 |
| Gallagher, J | 1 |
| Nockler, IB | 1 |
| Whitfield, HN | 1 |
| Fobbe, F | 1 |
| Boese-Landgraf, J | 1 |
| Chen, Y | 2 |
| Reichel, M | 1 |
| Schmoll, E | 1 |
| Wolf, KJ | 1 |
| Richardson, P | 2 |
| Steingart, R | 2 |
| Pokela, ML | 1 |
| Rowbottom, SJ | 1 |
| Tabrizian, I | 1 |
| Armstrong, PJ | 2 |
| Morton, CP | 1 |
| Nimmo, AF | 1 |
| Barsan, WG | 1 |
| Tomassoni, AJ | 1 |
| Seger, D | 1 |
| Danzl, DF | 1 |
| Ling, LJ | 1 |
| Bartlett, R | 1 |
| Aaen, V | 1 |
| Cowan, L | 1 |
| Sakala, EP | 1 |
| Small, ML | 1 |
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| Ward, SJ | 1 |
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| Joranson, DE | 1 |
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Clinical Trials (35)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Controlled Trial of Transcutaneous Electrical Nerve Stimulation for Pain Relief During Transvaginal Oocyte Retrieval Using Conscious Sedation[NCT03472430] | 160 participants (Actual) | Interventional | 2018-05-04 | Completed | |||
| Abdominal Compression Administered Early by the Colonoscopist Shortened Insertion Time of Water Exchange Colonoscopy[NCT03954561] | 120 participants (Actual) | Interventional | 2017-05-15 | Completed | |||
| Prospective RCT of Water Exchange (WE) vs. WE Plus Cap-Assisted Colonoscopy[NCT03160859] | 280 participants (Actual) | Interventional | 2018-06-08 | Completed | |||
| Randomized Controlled Trial Comparing the Impact of Water Assisted Colonoscopy vs Air Insufflation on Resident Training[NCT04987645] | 140 participants (Anticipated) | Interventional | 2022-06-22 | Enrolling by invitation | |||
| Bispectral Index Monitoring for Sedation in Elective Colonoscopies of Adult Patients: a Randomized Controlled Trial[NCT03453359] | 180 participants (Actual) | Interventional | 2018-01-28 | Completed | |||
| Preventive Application Of Lidocaine Patch In Adjunction To Intravenous Morphine Analgesia For Management Of Post-Thoracotomy Pain: Results Of A Randomized, Double Blind, Placebo Controlled Study[NCT02751619] | 90 participants (Actual) | Interventional | 2013-01-31 | Completed | |||
| [NCT01993589] | 144 participants (Actual) | Interventional | 2012-11-30 | Completed | |||
| Safety and Efficacy Evaluation of Remimazolam for Endoscopic Ultrasound-guided Fine Needle Aspiration/Biopsy[NCT05437497] | 264 participants (Anticipated) | Interventional | 2021-08-01 | Recruiting | |||
| [NCT02039453] | 160 participants (Anticipated) | Interventional | 2013-09-30 | Recruiting | |||
| Survey of Knowledge and Attitude of Pain in Anesthesia Residents of Thailand[NCT05369923] | 140 participants (Anticipated) | Observational | 2022-10-01 | Not yet recruiting | |||
| Goal Directed Propofol Sedation With Magnesium Sulphate Versus Dexmedetomidine for ERCP Procedure[NCT02684019] | Phase 3 | 60 participants (Actual) | Interventional | 2016-01-31 | Completed | ||
| Assessment of the Analgesic Efficacy of Intravenous Ibuprofen in Biliary Colic[NCT02268955] | 22 participants (Actual) | Interventional | 2014-09-09 | Completed | |||
| Etomidate With Meperidine vs Midazolam With Meperidine for Sedation During Endodscopic Retrograde Cholangiopancreatogram (ERCP)[NCT02027311] | Phase 4 | 63 participants (Actual) | Interventional | 2013-04-30 | Completed | ||
| Pethidine Versus Nitrous Oxide for Pain Relief During Labor Among Multiparous. A Randomized Controlled Trial[NCT02783508] | 214 participants (Actual) | Interventional | 2016-08-31 | Completed | |||
| An Open-label, Single-dose, Pharmacokinetic Study of Acetaminophen/Naproxen Sodium Fixed Combination Tablets in Adolescents 12 to <17 Years of Age With Orthodontic Pain[NCT05844995] | Phase 1 | 30 participants (Anticipated) | Interventional | 2023-09-13 | Recruiting | ||
| A Full-Factorial, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Single-Dose Efficacy and Safety Study of an Acetaminophen/Naproxen Sodium Fixed Combination, Acetaminophen, and Naproxen Sodium in Postoperative Dental Pain[NCT05761574] | Phase 3 | 440 participants (Anticipated) | Interventional | 2023-05-22 | Recruiting | ||
| Opioid-Induced Hyperalgesia in Prescription Opioid Abusers: Effects of Pregabalin[NCT01821430] | Phase 2 | 4 participants (Actual) | Interventional | 2013-03-31 | Terminated (stopped due to poor recruitment) | ||
| An Evaluation of the Paracervical Block for Pain Control in First Trimester Surgical Abortion[NCT01094366] | Phase 4 | 121 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| The Evaluation of the Combination of Magnesium and Lidocaine for the Pretreatment of Pain That is Caused by the Injection of Propofol.[NCT01342510] | Phase 4 | 200 participants (Actual) | Interventional | 2011-04-30 | Completed | ||
| Intravenous Sedation and Analgesia Using Propofol, Fentanyl and Ketamine (PFK) Versus General Anesthesia in Minor Urological Procedures.[NCT04285528] | 200 participants (Actual) | Interventional | 2019-04-17 | Completed | |||
| The Effect of Local Anesthesia With Lidocaine During Insertion and Removal of Nasal Packing[NCT04519463] | Early Phase 1 | 60 participants (Anticipated) | Interventional | 2020-09-30 | Not yet recruiting | ||
| A Randomised Control Trial to Determine Whether Intervention Based on a Microstream Capnography-based Ventilation Monitoring System Will Decrease Hypoxaemaia During Intravenous Sedation With Midazolam.[NCT01949012] | 190 participants (Actual) | Interventional | 2013-10-31 | Completed | |||
| Effects of Chronic Musculoskeletal Pain and Opioidergic Versus Placebo Interventions on Neuroendocrine Function in Men[NCT00737737] | Phase 4 | 8 participants (Actual) | Interventional | 2008-08-31 | Completed | ||
| Does Endoscope Position Detecting Unit Facilitate Caecal Intubation? A Randomized Controlled Trial[NCT01434199] | Phase 3 | 870 participants (Anticipated) | Interventional | 2011-07-31 | Recruiting | ||
| ScopeGuide-assisted Colonoscopy Versus Conventional Colonoscopy for Improved Endoscopic Performance and Enhanced Patient Experience[NCT01438645] | 250 participants (Actual) | Interventional | 2011-09-30 | Completed | |||
| Comparative Study of Microwave Ablation and Partial Splenic Embolization in the Management of Hypersplenism[NCT02261584] | 40 participants (Anticipated) | Interventional | 2014-08-31 | Recruiting | |||
| Intravenous Injection of Diazepam at the Beginning of Active Phase of Labor[NCT02232035] | Phase 2 | 400 participants (Anticipated) | Interventional | 2014-09-30 | Not yet recruiting | ||
| MORphine Use in the Fascia Iliaca Compartment Block With UltraSound[NCT03846102] | Phase 4 | 55 participants (Actual) | Interventional | 2019-01-28 | Terminated (stopped due to COVID-19 crisis.) | ||
| The Women In Steady Exercise Research (WISER) Survivor Trial & Cost of Illness and Cost Effectiveness of Alternative Management Strategies[NCT01515124] | 450 participants (Actual) | Interventional | 2012-01-31 | Completed | |||
| Pain During Pars Plana Vitrectomy Comparing Peribulbar Anesthesia Versus Sub-tenon Injection Plus Topical Jelly Anesthesia[NCT03902925] | Phase 1/Phase 2 | 56 participants (Actual) | Interventional | 2019-01-01 | Completed | ||
| The Effect of Using Blood Vessel Imaging Device on Pain and Satisfaction Level During the Phlebotomy Procedure[NCT05678504] | 100 participants (Actual) | Observational [Patient Registry] | 2022-04-01 | Completed | |||
| THE EFFECT OF USING CHLORHEXIDINE GLUCONATE AND POVIDONE IODINE SOLUTION ON THE HEALING PROCESS BEFORE A CESAREAN SECTION[NCT05953714] | 102 participants (Actual) | Interventional | 2020-12-01 | Completed | |||
| Comparison of Oral Gabapentin and Pregabalin in Postoperative Pain Control After Photorefractive Keratectomy: a Prospective, Randomized Study.[NCT00954187] | 8 participants (Actual) | Interventional | 2009-11-30 | Terminated (stopped due to PI left institution) | |||
| Home-based Approaches for Subacute Low Back Pain in Active Duty: Randomized, Controlled Trial[NCT03502187] | 133 participants (Actual) | Interventional | 2018-04-17 | Completed | |||
| A Prospective, Multicenter, Double-Blind, Randomized, Placebo-Controlled Study of Nitric Oxide for Inhalation in the Acute Treatment of Sickle Cell Pain Crisis[NCT00094887] | Phase 2 | 150 participants (Actual) | Interventional | 2004-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Trial Outcomes
Insertion Time
Time to cecum (clock display on monitor), faster insertion is a quality marker (NCT03160859)
Timeframe: Insertion time in minutes was measured during the duration of the colonoscopy procedure, which lasted on average for about 1 hour
| Intervention | Minutes (Mean) |
|---|---|
| Control Method | 18.8 |
| Study Method | 18.6 |
Proportion of Patients With No Insertion Pain
Proportion of patients who report no pain during insertion of the colonoscope. (NCT03160859)
Timeframe: Pain was measured during the duration of the colonoscopy procedure, which lasted on average for about 1 hour
| Intervention | Participants (Count of Participants) |
|---|---|
| Control Method | 38 |
| Study Method | 41 |
Real Time Maximum Insertion Pain
Pain during insertion reported to the unblinded assisting nurse, visual analogue scale, VAS: 0=none, 10=most severe. The highest pain score will be tabulated for analysis. Timing of data collection will be at the discretion of the nurse to minimize bias by colonoscopist behavior. (NCT03160859)
Timeframe: Insertion pain was measured during the duration of the colonoscopy procedure, which lasted on average for about 1 hour
| Intervention | score on a scale (Mean) |
|---|---|
| Control Method | 2.6 |
| Study Method | 2.9 |
Right Colon Adenoma Detection Rate (ADR)
Right colon Adenoma Detection Rate (ADR) is the proportion of patients with at least one adenoma in the part of the colon between the cecum and the hepatic flexure. (NCT03160859)
Timeframe: Adenoma Detection Rate (ADR) was measured during the duration of the colonoscopy procedure, which lasted on average for about 1 hour
| Intervention | Participants (Count of Participants) |
|---|---|
| Control Method | 40 |
| Study Method | 27 |
Pain Score 120 Minutes After Study Medication Administration
Pain is measured on a visual analog scale 0=no pain and 10=worst pain imaginable. (NCT02268955)
Timeframe: 120 minutes post medication administration
| Intervention | score on a scale (Median) |
|---|---|
| Control Group: Adults Age 18-55 Years | 3.0 |
| IV Ibuprofen: Adults Age 18-55 Years | 0.3 |
Event of Hypoxia
Hypoxia defined as peripheral blood oxygen saturation measured by pulse oxymeter < 90% (NCT02027311)
Timeframe: Every 5min in Preoperative, intraoperative phase and 15 min in Recovery phase
| Intervention | Hypoxia events (Number) |
|---|---|
| Midazolam | 19 |
| Etomidate | 27 |
Number of Intervention
The frequency of intervention which was defined as any restraint of the patient's head, arms, or legs if they became agitated, or if patient movement was not controlled with verbal instruction from the endoscopist during the whole intraoperative phases. (NCT02027311)
Timeframe: Throughout the whole ERCP procedure
| Intervention | Number of intervention (Mean) |
|---|---|
| Etomidate | 1.9 |
| Midazolam | 7.5 |
Number of Patients With Pain Associated With Injection of Propofol.
"Ten seconds following injection of propofol, subjects were asked Are you having pain at your IV site? Any behavioral signs were noted. Injection pain was assessed using the following four point scale: 0 = no pain; 1 = mild pain (pain reported only in response to questioning and without behavioral signs); 2 = moderate pain (pain reported in response to questioning and accompanied by a behavioral sign, or pain reported spontaneously without questioning); and 3 = severe pain (strong vocal response or response accompanied by facial grimacing, arm withdrawal, or tears)." (NCT01342510)
Timeframe: < 1 minute.
| Intervention | participants reporting pain (Number) |
|---|---|
| Lidocaine | 11 |
| Magnesium | 25 |
| Lidocaine/Magnesium | 15 |
| Control | 18 |
Percentage of Participants Reporting Pain With Injection of Propofol
Following injection of the study drug, 50 mg of propofol will be injected. Ten seconds after propofol, subjects will be asked a standard question about pain. Behavioral signs will be noted. Pain will be assessed using a four point scale: 0=no pain, 1=mild pain (pain reported only in response to questioning and without behavioral signs), 2=moderate pain (pain reported in response to questioning and a behavioral sign, or pain reported without questioning), 3=severe pain (strong vocal response or behavioral response). (NCT01342510)
Timeframe: Approximately 10 seconds following administration of propofol.
| Intervention | percentage of patients reporting pain (Number) |
|---|---|
| Lidocaine | 29 |
| Magnesium | 57 |
| Lidocaine/Magnesium | 41 |
| Control | 46 |
Is Chronic Opioid Treatment Associated With Changes in Adrenocorticotropic Hormone (ACTH), Cortisol, Luteinizing Hormone (LH) and Testosterone Secretion?
(NCT00737737)
Timeframe: 4 weeks
| Intervention | ng/ml (Number) |
|---|---|
| Opioid | NA |
| Placebo | NA |
Is Placebo Analgesia Associated With a Similar Hormonal Response as Elicited by an Opioid Analgesic?
(NCT00737737)
Timeframe: 4 weeks
| Intervention | ng/ml (Number) |
|---|---|
| Opioid | NA |
| Placebo | NA |
Current Pain Severity
"The Visual Analog Scale (VAS) of pain will be used to assess pain at rest and after activity. (Revill et al., 1976) Participants will complete this scale following the push-ups, sit-ups, 6-minute walk and the lumbar trunk muscle test. This VAS pain subscale is a 10-cm horizontal line index with descriptive anchors at each end. At the far left (0.0 cm) is no pain and at the far right (10 cm) is worst possible pain. The participant is instructed to place a vertical line at some point between the anchors to describe their level of pain." (NCT03502187)
Timeframe: 0, 3, 6, 9 Weeks
| Intervention | score on a scale (Mean) | |||
|---|---|---|---|---|
| Week 0 | Week 3 | Week 6 | Week 9 | |
| NeuromuscularElectricalStimulation(NMES) | 4.57 | 4.54 | 3.96 | 4.07 |
| Primary Care Management (PCM) | 4.43 | 3.88 | 4.03 | 3.28 |
| Progressive Exercise Plan (PEP) | 4.78 | 4.47 | 4.70 | 3.93 |
Depressive Symptoms-Center for Epidemiologic Studies Depression (CES-D) Scale
The Center for Epidemiologic Studies Depression (CES-D) scale is a self-report questionnaire that contains 20 items. Participants were asked to rate how often over the past week they experienced symptoms associated with depression. Scores range from 0-60 with high scores denoting greater depressive symptoms. CES-D scores were recorded at baseline (0 weeks) and subsequent visits. If the baseline score was greater than 23 the participants were not randomized. (NCT03502187)
Timeframe: 0, 3, 6, 9 Weeks
| Intervention | score on a scale (Mean) | |||
|---|---|---|---|---|
| Week 0 | Week 3 | Week 6 | Week 9 | |
| NeuromuscularElectricalStimulation(NMES) | 6.05 | 6.46 | 6.55 | 6.20 |
| Primary Care Management (PCM) | 6.84 | 7.78 | 6.13 | 5.70 |
| Progressive Exercise Plan (PEP) | 6.26 | 7.12 | 8.06 | 7.63 |
Impact of Bodily Pain on Normal Work Measured by SF12v2
The Short Form Health Survey Version 2.0 (SF-12v2) Health Survey will be used to determine each participant's overall impact of bodily pain on normal work. The SF12v2 has a question that asks participants to assess the impact of pain on normal work during the previous 4 weeks using options ranging from Not at all to Extremely. Responses are translated to numerical scores ranging from 0 to 100. Higher scores indicate less impact of bodily pain. (NCT03502187)
Timeframe: 0, 3, 6, 9 Weeks
| Intervention | score on a scale (Mean) | |||
|---|---|---|---|---|
| Week 0 | Week 3 | Week 6 | Week 9 | |
| NeuromuscularElectricalStimulation(NMES) | 44 | 58.8 | 61.4 | 72.1 |
| Primary Care Management (PCM) | 53.6 | 59.0 | 59.2 | 72.0 |
| Progressive Exercise Plan (PEP) | 47.6 | 55.9 | 58.6 | 65.8 |
Lower Back Strength-Extension
Torso extension muscle strength is measured with a modified version of the U of Michigan strength test system (Workability Systems, West Chester, Ohio) and a Chattanooga-Baseline® Hand Dynamometer - Digital LCD Gauge - ER™ 300 lb capacity (DJO Global, Chattanooga, Vista, CA USA). To measure trunk extension, the participant stands with their lower anterior abdomen against the padded board. The belt is placed around the posterior back and under the arms. Participants pull against the belt as forcefully as possible. Participants perform two maximal efforts maintaining each voluntary isometric exertion for 5 seconds, separated by 30-second rest; the highest value of the two trials will be accepted. (NCT03502187)
Timeframe: 0, 3, 6, and 9 weeks
| Intervention | kg-Force (Mean) | |||
|---|---|---|---|---|
| Week 0 | Week 3 | Week 6 | Week 9 | |
| NeuromuscularElectricalStimulation(NMES) | 50.2 | 61.4 | 69.0 | 69.3 |
| Primary Care Management (PCM) | 54.5 | 57.5 | 68.2 | 69.4 |
| Progressive Exercise Plan (PEP) | 49.2 | 54.6 | 53.1 | 55.1 |
Lower Back Strength-Flexion
Torso flexion muscle strength is measured with a modified version of the U of Michigan strength test system (Workability Systems, West Chester, Ohio) and a Chattanooga-Baseline® Hand Dynamometer - Digital LCD Gauge - ER™ 300 lb capacity (DJO Global, Chattanooga, Vista, CA USA). For trunk flexion, the participant stands in the apparatus, buttocks against the padded board, the superior edge level with the iliac crest. A canvas belt is around the chest and under the arms horizontal to the force-measuring dynamometer on the apparatus frame. Participants pull against the belt as forcefully as possible. Participants perform two maximal efforts maintaining each voluntary isometric exertion for 5 seconds, separated by 30-second rest; the highest value of the two trials will be accepted. (NCT03502187)
Timeframe: 0, 3, 6, and 9 weeks
| Intervention | kg-Force (Mean) | |||
|---|---|---|---|---|
| Week 0 | Week 3 | Week 6 | Week 9 | |
| NeuromuscularElectricalStimulation(NMES) | 48.8 | 57.9 | 63.7 | 60.9 |
| Primary Care Management (PCM) | 51.6 | 52.1 | 65.6 | 65.1 |
| Progressive Exercise Plan (PEP) | 43.7 | 47.7 | 44.4 | 47.9 |
Mobility/Function Measured by the 2-minute Push-up Test
The 2-minute push-up test evaluates upper body endurance and strength as well as the stabilizing torso muscles of the abdomen and back. Starting in a prone position, the participant is positioned with their hands on the ground (shoulder width apart), toes in contact with the floor, spine parallel to the floor, elbows and hips in extension. The body moves as a single rigid unit and is lowered to the ground until elbows are at 90° angle. The body is then returned to the starting position by pushing the arms up to full extension. A push-up is counted if the elbows were brought to flexion of 90° or greater and then return to full extension, while keeping the body elevated on the toes. The number of push-ups performed in 2-minutes is recorded. (NCT03502187)
Timeframe: 0, 3, 6, 9 Weeks
| Intervention | Number of push-ups (Mean) | |||
|---|---|---|---|---|
| Week 0 | Week 3 | Week 6 | Week 9 | |
| NeuromuscularElectricalStimulation(NMES) | 41.1 | 40.3 | 42.3 | 46.0 |
| Primary Care Management (PCM) | 46.9 | 46.0 | 45.9 | 46.2 |
| Progressive Exercise Plan (PEP) | 43.7 | 47.4 | 42.2 | 46.3 |
Mobility/Function Measured by the 2-minute Sit-up Test
The 2-minute sit-up test measures trunk flexion and abdominal endurance. Starting in a supine position, the knee joints are flexed at a 90° angle, with fingers behind the head, soles of the feet and shoulder blades in contact with the floor. With the command to begin, the upper body is raised forward by flexing the abdominal muscles and then lowered. A sit-up is counted if the hands are behind the head, bringing the base of the spine to a vertical position and then returning the shoulder blades to the floor. The number of repetitions performed in 2 minutes is recorded. (NCT03502187)
Timeframe: 0, 3, 6, 9 Weeks
| Intervention | Number of sit-ups (Mean) | |||
|---|---|---|---|---|
| Week 0 | Week 3 | Week 6 | Week 9 | |
| NeuromuscularElectricalStimulation(NMES) | 35.5 | 38.7 | 43.2 | 43.5 |
| Primary Care Management (PCM) | 44.4 | 44.9 | 45.6 | 51.0 |
| Progressive Exercise Plan (PEP) | 41.5 | 43.2 | 40.8 | 45.0 |
Mobility/Function Measured by the 6-minute Walk Test
"The 6-Minute Walk Test (6-MWT) measures the distance a participant walks at a fast pace over a 6-minute period. Participants will walk as quickly as you can with the opportunity to stop and rest if required. This test measures functional capacity of walking. Healthy adults are expected to walk between 400 and 700 meters [1300-2300 feet] on the 6-minute walk test (Enright, 2003). Outcomes are reported in feet walked." (NCT03502187)
Timeframe: 0, 3, 6, 9 Weeks
| Intervention | Number of feet (Mean) | |||
|---|---|---|---|---|
| Week 0 | Week 3 | Week 6 | Week 9 | |
| NeuromuscularElectricalStimulation(NMES) | 1868 | 1889 | 1925 | 1883 |
| Primary Care Management (PCM) | 1940 | 2020 | 1996 | 2041 |
| Progressive Exercise Plan (PEP) | 1858 | 1882 | 1904 | 1924 |
Physical Activity
Physical activity will be measured using the Fitbit Charge 2 (San Francisco, CA). The Charge 2 is a wrist-worn three-axis accelerometer that measures steps walked, distance traveled, energy expenditure and floors climbed. The unique feature of this device is a wireless function that automatically uploads data to designated mobile phone devices or computers. Physical Activity is reported as average Kcal expended during a seven day period. (NCT03502187)
Timeframe: 0, 3, 6, 9 Weeks
| Intervention | Kcal (Mean) | |||
|---|---|---|---|---|
| Week 0 | Week 3 | Week 6 | Week 9 | |
| NeuromuscularElectricalStimulation(NMES) | 3005 | 2950 | 2955 | 2922 |
| Primary Care Management (PCM) | 2733 | 2691 | 2599 | 2605 |
| Progressive Exercise Plan (PEP) | 2912 | 2809 | 2609 | 2559 |
Length of Hospitalization
Length of hospitalization is defined as the length of time from admission to discharge order (NCT00094887)
Timeframe: within 40 days
| Intervention | Days (Median) |
|---|---|
| Inhaled Nitric Oxide | 4.06 |
| Placebo | 3.11 |
Number of Participants Discharged to Home Within the First 24 Hours
(NCT00094887)
Timeframe: within 24 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| Inhaled Nitric Oxide | 5 |
| Placebo | 7 |
Number of Participants With Acute Chest Syndrome/Pneumonia Requiring Blood Transfusion
Number of participants who required a blood transfusion before discharge because of acute chest syndrome/pneumonia (NCT00094887)
Timeframe: within 40 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Inhaled Nitric Oxide | 8 |
| Placebo | 7 |
Time to Vaso-occlusive Pain Crisis (VOC) Resolution
"VOC resolution was defined by all of the following conditions:~Pain relief - Visual Analog Scale (VAS) pain scores of 6 or less, (6 as worst and 0 as best)~Freedom from parenteral narcotic use,~Ability to walk unless the subject was not able to walk for any reason other than acute VOC prior to the onset of crisis,~Subject and/or family's belief that the painful crisis could be managed at home with or without oral analgesic use, and the physician concurred with that assessment." (NCT00094887)
Timeframe: within 30 days
| Intervention | Hours (Median) |
|---|---|
| Inhaled Nitric Oxide | 61.83 |
| Placebo | 55.16 |
Number of Participants Readmitted to Hospital Within 30 Days After Discharge
The number of participants readmitted to the hospital for any reason within 30 days after discharge (NCT00094887)
Timeframe: during first 24 hours and during 30 day follow-up
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| during first 24 hours | during 30-day follow-up | |
| Inhaled Nitric Oxide | 0 | 9 |
| Placebo | 0 | 17 |
Total Dose of Opioids Received
The total dose (mg) of opioid medications received during the trial (NCT00094887)
Timeframe: within 8 hours and within 40 days
| Intervention | mg (Median) | |
|---|---|---|
| within 8 hours | within 40 days | |
| Inhaled Nitric Oxide | 16.25 | 153.75 |
| Placebo | 17.25 | 211.37 |
Reviews
22 reviews available for meperidine and Ache
| Article | Year |
|---|---|
The Comparative Risk of Delirium with Different Opioids: A Systematic Review.
Topics: Aged; Analgesics, Opioid; Delirium; Humans; Hydromorphone; Meperidine; Morphine; Oxycodone; Pain; Pa | 2017 |
[Pain perception of the fetus].
Topics: Analgesics, Opioid; Biomarkers; Facial Expression; Fetal Blood; Fetus; Heart Rate; Humans; Meperidin | 2010 |
Sample Power and ExpDesign: tools for improving design of animal experiments.
Topics: Analgesics; Animal Welfare; Animals; Computer-Assisted Instruction; Drug Evaluation, Preclinical; Ho | 2003 |
Acute pancreatitis.
Topics: Acute Disease; Analgesia; Analgesics, Opioid; Clinical Protocols; Emergency Medical Services; Fluid | 2004 |
The drug-seeking patient in the emergency room.
Topics: Analgesics, Opioid; Chronic Disease; Emergency Medicine; Emergency Service, Hospital; Humans; Meperi | 2005 |
Should New Zealand continue signing up to the Pethidine Protocol?
Topics: Analgesics, Opioid; Cost-Benefit Analysis; Drug and Narcotic Control; Drug Evaluation; Drug Interact | 2006 |
[Intranasal opioids for acute pain].
Topics: Absorption; Acute Disease; Administration, Intranasal; Adult; Analgesia, Patient-Controlled; Analges | 2006 |
WITHDRAWN: Types of intra-muscular opioids for maternal pain relief in labour.
Topics: Analgesia, Obstetrical; Analgesics, Opioid; Female; Humans; Injections, Intramuscular; Labor, Obstet | 2007 |
The practical use of narcotic analgesics.
Topics: Analgesics, Opioid; Drug Evaluation; Drug Therapy, Combination; Drug Tolerance; Humans; Meperidine; | 1982 |
Spinal opiate analgesia: characteristics and principles of action.
Topics: Analgesia; Anesthesia; Animals; Autonomic Nervous System; Hemodynamics; Humans; Meperidine; Morphine | 1981 |
Systemic analgesia during labor.
Topics: Acid-Base Equilibrium; Analgesics; Animals; Child Behavior; Diazepam; Female; Fentanyl; Fetal Heart; | 1982 |
Traditional analgesic agents: are parenteral narcotics passé and do inhalational agents still have a place in labour?
Topics: Administration, Inhalation; Analgesia, Obstetrical; Female; Humans; Infusions, Parenteral; Meperidin | 1998 |
ABC of labour care. Relief of pain.
Topics: Adaptation, Psychological; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthetics, Inhalation; Fem | 1999 |
[Meperidine (pethidine) outdated as analgesic in acute pancreatitis].
Topics: Acute Disease; Analgesics, Opioid; Contraindications; Dyskinesia, Drug-Induced; Erythema; Humans; Hy | 2000 |
Types of intra-muscular opioids for maternal pain relief in labour.
Topics: Analgesia, Obstetrical; Analgesics, Opioid; Female; Humans; Injections, Intramuscular; Labor, Obstet | 2000 |
Pediatric pain: current status and new directions.
Topics: Child; Child, Preschool; Chlorpromazine; Drug Combinations; Humans; Infant; Infant, Newborn; Meperid | 1990 |
[Use of epidural and intrathecal opiates in obstetrics].
Topics: Adult; Analgesia, Epidural; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthe | 1989 |
The pharmacologic management of pain in children.
Topics: Analgesia, Epidural; Analgesics; Child; Child, Preschool; Codeine; Fentanyl; Humans; Infant; Meperid | 1989 |
Management of pediatric pain with opioid analgesics.
Topics: Analgesics, Opioid; Child; Codeine; Fentanyl; Humans; Infant; Meperidine; Morphine; Narcotic Antagon | 1988 |
Obstetric medication and neonatal behavior. Current controversies.
Topics: Analgesics; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics; Anesthetics, Local; Animals; | 1985 |
Drug therapy: analgetic drugs--the potent analgetics.
Topics: Analgesics; Blood Circulation; Fentanyl; Humans; Intestines; Levallorphan; Meperidine; Methadone; Me | 1972 |
Propoxyphene hydrochloride. A critical review.
Topics: Analgesics; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Female; Headac | 1970 |
Trials
112 trials available for meperidine and Ache
| Article | Year |
|---|---|
Randomized single-blind comparative study of the midazolam/pethidine combination and midazolam alone during bronchoscopy.
Topics: Bronchoscopy; Conscious Sedation; Humans; Meperidine; Midazolam; Pain; Prospective Studies; Single-B | 2022 |
Analgesic Characteristics of Bupivacaine Alone and in Combination with Dexmedetomidine or Meperidine in Spinal Anesthesia during Cesarean Section: A Double-Blind Randomized Clinical Trial Study.
Topics: Analgesics; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Cesarean Section; Dexmedetomidine; | 2022 |
Meperidine Compared With Nitrous Oxide for Intrapartum Pain Relief in Multiparous Patients: A Randomized Controlled Trial.
Topics: Analgesia, Obstetrical; Analgesics; Analgesics, Opioid; Female; Humans; Infant, Newborn; Meperidine; | 2023 |
Efficacy of pethidine, ketorolac, and lidocaine gel as analgesics for pain control in shockwave lithotripsy: A single-blinded randomized controlled trial.
Topics: Adult; Analgesia; Analgesics; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non- | 2019 |
Magnetic endoscopic imaging during colonoscopy is associated with less pain and decreased need of analgesia and sedation--results from a randomized controlled trial.
Topics: Adult; Aged; Analgesics, Opioid; Cecum; Colonoscopy; Female; Humans; Hypnotics and Sedatives; Imagin | 2013 |
Patient-Controlled Remifentanil Analgesia as Alternative for Pethidine with Midazolam During Oocyte Retrieval in IVF/ICSI Procedures: A Randomized Controlled Trial.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Intravenous; Drug Therapy, Co | 2015 |
Meperidine relieves pain during transrectal ultrasound-guided prostate biopsy.
Topics: Analgesics, Opioid; Biopsy; Double-Blind Method; Humans; Male; Meperidine; Pain; Prostate; Rectum; U | 2014 |
A patient-blinded randomized, controlled trial comparing air insufflation, water immersion, and water exchange during minimally sedated colonoscopy.
Topics: Adenoma; Adult; Aged; Air; Analgesics, Opioid; Colonic Neoplasms; Colonoscopy; Conscious Sedation; F | 2014 |
A patient-blinded randomized, controlled trial comparing air insufflation, water immersion, and water exchange during minimally sedated colonoscopy.
Topics: Adenoma; Adult; Aged; Air; Analgesics, Opioid; Colonic Neoplasms; Colonoscopy; Conscious Sedation; F | 2014 |
A patient-blinded randomized, controlled trial comparing air insufflation, water immersion, and water exchange during minimally sedated colonoscopy.
Topics: Adenoma; Adult; Aged; Air; Analgesics, Opioid; Colonic Neoplasms; Colonoscopy; Conscious Sedation; F | 2014 |
A patient-blinded randomized, controlled trial comparing air insufflation, water immersion, and water exchange during minimally sedated colonoscopy.
Topics: Adenoma; Adult; Aged; Air; Analgesics, Opioid; Colonic Neoplasms; Colonoscopy; Conscious Sedation; F | 2014 |
A patient-blinded randomized, controlled trial comparing air insufflation, water immersion, and water exchange during minimally sedated colonoscopy.
Topics: Adenoma; Adult; Aged; Air; Analgesics, Opioid; Colonic Neoplasms; Colonoscopy; Conscious Sedation; F | 2014 |
A patient-blinded randomized, controlled trial comparing air insufflation, water immersion, and water exchange during minimally sedated colonoscopy.
Topics: Adenoma; Adult; Aged; Air; Analgesics, Opioid; Colonic Neoplasms; Colonoscopy; Conscious Sedation; F | 2014 |
A patient-blinded randomized, controlled trial comparing air insufflation, water immersion, and water exchange during minimally sedated colonoscopy.
Topics: Adenoma; Adult; Aged; Air; Analgesics, Opioid; Colonic Neoplasms; Colonoscopy; Conscious Sedation; F | 2014 |
A patient-blinded randomized, controlled trial comparing air insufflation, water immersion, and water exchange during minimally sedated colonoscopy.
Topics: Adenoma; Adult; Aged; Air; Analgesics, Opioid; Colonic Neoplasms; Colonoscopy; Conscious Sedation; F | 2014 |
A patient-blinded randomized, controlled trial comparing air insufflation, water immersion, and water exchange during minimally sedated colonoscopy.
Topics: Adenoma; Adult; Aged; Air; Analgesics, Opioid; Colonic Neoplasms; Colonoscopy; Conscious Sedation; F | 2014 |
Randomized comparison of recovery time after use of remifentanil alone versus midazolam and meperidine for colonoscopy anesthesia.
Topics: Analgesics, Opioid; Anesthesia; Anesthesia Recovery Period; Anesthetics, Intravenous; Colonoscopy; D | 2015 |
Use of pethidine for percutaneous liver biopsy - a randomised, placebo-controlled, double blind study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Biopsy; Double-Blind Method; Female; | 2015 |
Lidocaine Skin Patch (Lidopat® 5%) Is Effective in the Treatment of Traumatic Rib Fractures: A Prospective Double-Blinded and Vehicle-Controlled Study.
Topics: Analgesics, Opioid; Anesthetics, Local; Double-Blind Method; Drug Utilization; Female; Humans; Lengt | 2016 |
Effect of paracetamol, dexketoprofen trometamol, lidocaine spray, pethidine & diclofenac sodium application for pain relief during fractional curettage: A randomized controlled trial.
Topics: Acetaminophen; Adult; Aged; Analgesia; Curettage; Diclofenac; Female; Gynecologic Surgical Procedure | 2015 |
Nurse-administered propofol sedation compared with midazolam and meperidine for EUS: a prospective, randomized trial.
Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Anesthesia Recovery Period; Anesthetics, Intravenou | 2008 |
Effects of meperidine or saline on thermal, mechanical and electrical nociceptive thresholds in cats.
Topics: Animals; Cats; Electric Stimulation; Female; Hot Temperature; Male; Meperidine; Pain; Pressure | 2008 |
[Analgesic effect of acupuncture compound anesthesia for patients of different pain thresholds].
Topics: Acupuncture Analgesia; Adult; Analgesics; Combined Modality Therapy; Embryo Transfer; Female; Fertil | 2009 |
Comparisons of ice packs, hot water immersion, and analgesia injection for the treatment of centipede envenomations in Taiwan.
Topics: Adult; Analgesics, Opioid; Animals; Arthropod Venoms; Arthropods; Cold Temperature; Cryotherapy; Fem | 2009 |
Electro-acupuncture for pain relief after nasal septoplasty: a randomized controlled study.
Topics: Adolescent; Adult; Analgesia; Analgesics, Opioid; Double-Blind Method; Electroacupuncture; Female; H | 2010 |
Sedation with midazolam versus midazolam plus meperidine for routine colonoscopy: a prospective, randomized, controlled study.
Topics: Adult; Aged; Analgesics, Opioid; Blood Pressure; Colonoscopy; Conscious Sedation; Drug Therapy, Comb | 2009 |
Efficacy of tramadol vs meperidine in vasoocclusive sickle cell crisis.
Topics: Acute Disease; Analgesics, Opioid; Anemia, Sickle Cell; Blood Pressure; Emergency Service, Hospital; | 2010 |
PCA analgesia for children with chemotherapy-related mucositis: a double-blind randomized comparison of morphine and pethidine.
Topics: Adolescent; Analgesics, Opioid; Antineoplastic Agents; Child; Child, Preschool; Double-Blind Method; | 2011 |
Open haemorrhoidectomy under local anaesthesia for symptomatic haemorrhoids: An experience from Nigeria.
Topics: Adult; Aged; Anal Canal; Anesthesia, Local; Anesthetics, Local; Conscious Sedation; Constriction, Pa | 2011 |
Topical EMLA for pain control during extracorporeal shock wave lithotripsy: prospective, comparative, randomized, double-blind study.
Topics: Adult; Aged; Anesthetics, Combined; Body Mass Index; Double-Blind Method; Female; Humans; Lidocaine; | 2012 |
A prospective randomized trial comparing patient-controlled sedation using propofol and alfentanil and physician-administered sedation using diazepam and pethidine during transvaginal ultrasound-guided oocyte retrieval.
Topics: Adult; Alfentanil; Analgesia, Patient-Controlled; Analgesics, Opioid; Conscious Sedation; Diazepam; | 2002 |
Comparison of intravenous ketorolac and meperidine in the treatment of biliary colic.
Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Biliary Tract Diseases; Colic; D | 2002 |
Effectiveness of intravenous meperidine for pain relief in the first stage of labour.
Topics: Adult; Analgesia, Obstetrical; Analgesics, Opioid; Chi-Square Distribution; Double-Blind Method; Fem | 2002 |
Single bolus of midazolam versus bolus midazolam plus meperidine for colonoscopy: a prospective, randomized, double-blind trial.
Topics: Analgesics, Opioid; Colonoscopy; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hyp | 2003 |
Pethidine versus tramadol for pain relief during labor.
Topics: Analgesics, Opioid; Female; Humans; Meperidine; Obstetric Labor Complications; Pain; Pain Measuremen | 2003 |
Patient-controlled sedation for colonoscopy: a randomized trial comparing patient-controlled administration of propofol and alfentanil with physician-administered midazolam and pethidine.
Topics: Adjuvants, Anesthesia; Adult; Aged; Aged, 80 and over; Alfentanil; Analgesia, Patient-Controlled; An | 2003 |
Periprostatic lidocaine infiltration and/or synthetic opioid (meperidine or tramadol) administration have no analgesic benefit during prostate biopsy. A prospective randomized double-blind placebo-controlled study comparing different methods.
Topics: Analgesics, Opioid; Anesthetics, Local; Biopsy; Double-Blind Method; Humans; Lidocaine; Male; Meperi | 2004 |
A double blinded randomised placebo-controlled study of intramuscular pethidine for pain relief in the first stage of labour.
Topics: Adult; Analgesia, Obstetrical; Analgesics, Opioid; Double-Blind Method; Female; Humans; Injections, | 2004 |
Morphine induces less nausea than meperidine when administered parenterally.
Topics: Adult; Aged; Analgesics, Opioid; Community Health Services; Dose-Response Relationship, Drug; Emerge | 2004 |
Reduction of pain on injection of propofol using meperidine and remifentanil.
Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Intravenous; Dose-Response Relationship, Drug; Double- | 2005 |
A randomized comparison of different methods of analgesia in abortion using manual vacuum aspiration.
Topics: Abortion, Incomplete; Adult; Analgesia, Obstetrical; Anesthesia, Obstetrical; Anti-Inflammatory Agen | 2007 |
The analgesic effect of inhalational Entonox for extracorporeal shock wave lithotripsy.
Topics: Adult; Analgesics, Opioid; Anesthesia, Inhalation; Anesthetics, Combined; Female; Humans; Lithotrips | 2007 |
Painless injection of propofol: pretreatment with ketamine vs thiopental, meperidine, and lidocaine.
Topics: Adult; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Intravenous; Anesthetics, Local; | 2007 |
Painless injection of propofol: pretreatment with ketamine vs thiopental, meperidine, and lidocaine.
Topics: Adult; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Intravenous; Anesthetics, Local; | 2007 |
Painless injection of propofol: pretreatment with ketamine vs thiopental, meperidine, and lidocaine.
Topics: Adult; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Intravenous; Anesthetics, Local; | 2007 |
Painless injection of propofol: pretreatment with ketamine vs thiopental, meperidine, and lidocaine.
Topics: Adult; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Intravenous; Anesthetics, Local; | 2007 |
The effect of prilocaine and prilocaine plus meperidine infiltration on the pain during nasal packing removal.
Topics: Adolescent; Adult; Analgesics, Opioid; Device Removal; Drug Combinations; Female; Formaldehyde; Hemo | 2007 |
Alterations in response to somatic pain associated with anaesthesia. 18. Studies with some opiate antagonists.
Topics: Female; Humans; Injections, Intramuscular; Injections, Intravenous; Levallorphan; Meperidine; Nalorp | 1967 |
An evaluation of the efficacy of nasogastric suction treatment in alcoholic pancreatitis.
Topics: Abdomen; Adult; Alcoholism; Amylases; Evaluation Studies as Topic; Fasting; Fluid Therapy; Humans; I | 1981 |
Self-administered intravenous and intramuscular pethidine. A controlled trial in labour.
Topics: Adult; Anesthesia, Inhalation; Anesthesia, Obstetrical; Clinical Trials as Topic; Drug Administratio | 1980 |
Maternal opinion about analgesia for labour. A controlled trial between epidural block and intramuscular pethidine combined with inhalation.
Topics: Adult; Analgesia; Anesthesia, Epidural; Anesthesia, Inhalation; Anesthesia, Obstetrical; Bupivacaine | 1980 |
A comparison of meptazinol and pethidine for pain relief during the first stage of labour.
Topics: Azepines; Blood Pressure; Clinical Trials as Topic; Female; Humans; Labor Stage, First; Labor, Obste | 1981 |
[Epidural application of opiates in chronic pain due to malignoma (author's transl)].
Topics: Adult; Aged; Catheterization; Female; Fentanyl; Humans; Male; Meperidine; Middle Aged; Morphine; Nar | 1981 |
Comparison of the effects of meperidine and nalbuphine on intrapartum fetal heart rate tracings.
Topics: Adolescent; Adult; Cardiotocography; Female; Heart Rate, Fetal; Humans; Infusions, Intravenous; Mepe | 1995 |
Effects of maternal pethidine on infants' developing breast feeding behaviour.
Topics: Adult; Breast Feeding; Female; Humans; Infant, Newborn; Male; Meperidine; Mother-Child Relations; Ob | 1995 |
Alfentanil for conscious sedation during colonoscopy.
Topics: Adult; Aged; Aged, 80 and over; Alfentanil; Anesthesia Recovery Period; Blood Pressure; Colonoscopy; | 1995 |
Prophylactic antiemetic treatment with ondansetron in children undergoing tonsillectomy.
Topics: Acetaminophen; Antiemetics; Child; Child, Preschool; Double-Blind Method; Droperidol; Female; Humans | 1994 |
Choosing the correct pain relief for extracorporeal lithotripsy.
Topics: Adult; Aged; Analgesia; Diclofenac; Female; Humans; Infusions, Intravenous; Lithotripsy; Male; Meper | 1994 |
Pain relief can reduce hypoxemia in distressed neonates during routine treatment procedures.
Topics: beta-Endorphin; Humans; Hydrocortisone; Hypoxia; Infant Care; Infant, Newborn; Meperidine; Oxygen; P | 1994 |
Pethidine has a local anaesthetic action on peripheral nerves in vivo. Addition to prilocaine 0.25% for intravenous regional anaesthesia in volunteers.
Topics: Adult; Anesthesia, Conduction; Anesthesia, Local; Arm; Double-Blind Method; Humans; Male; Meperidine | 1993 |
Safety assessment of high-dose narcotic analgesia for emergency department procedures.
Topics: Adolescent; Adult; Analysis of Variance; Blood Pressure; Body Temperature; Consciousness; Emergency | 1993 |
Intra-articular ultrasonic stimulation and intracutaneous electrical stimulation: evoked potential and visual analogue scale data.
Topics: Cartilage, Articular; Electric Stimulation; Evoked Potentials; Humans; Meperidine; Pain; Pain Measur | 1993 |
Is intra-articular pethidine an alternative to local anaesthetics in arthroscopy? A double-blind study comparing prilocaine with pethidine.
Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Arthroscopy; Double-Blind Method; Female; Humans; Inj | 1993 |
A prospective randomized study comparing needles of different diameters for transvaginal ultrasound-directed follicle aspiration.
Topics: Adult; Embryo Transfer; Female; Fertilization in Vitro; Humans; Meperidine; Needles; Oocytes; Pain; | 1996 |
Modification of pain on injection of propofol. A comparison of pethidine and lignocaine.
Topics: Adult; Analgesics, Opioid; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Female | 1996 |
Comparison of oral transmucosal fentanyl citrate and intramuscular meperidine, promethazine, and chlorpromazine for conscious sedation of children undergoing laceration repair.
Topics: Administration, Oral; Analgesics, Opioid; Child, Preschool; Chlorpromazine; Dermatologic Surgical Pr | 1996 |
Lack of analgesic effect of systemically administered morphine or pethidine on labour pain.
Topics: Adult; Analgesia, Obstetrical; Analgesics, Opioid; Anxiety; Dose-Response Relationship, Drug; Double | 1996 |
A comparison of morphine, pethidine and fentanyl in the postsurgical patient-controlled analgesia environment.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Double-Blind Method; Female; Fentany | 1996 |
Sedation and analgesia for colonoscopy: patient tolerance, pain, and cardiorespiratory parameters.
Topics: Adult; Aged; Analgesia; Analgesics, Opioid; Analysis of Variance; Anesthetics, Combined; Anesthetics | 1997 |
Analgesia following arthroscopy--a comparison of intra-articular morphine, pethidine and fentanyl.
Topics: Acetaminophen; Adult; Alfentanil; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; | 1997 |
Use of patient-controlled analgesia in extracorporeal shockwave lithotripsy.
Topics: Adolescent; Adult; Aged; Alfentanil; Analgesia, Patient-Controlled; Analgesics, Opioid; Female; Huma | 1997 |
The value of end-tidal CO2 monitoring when comparing three methods of conscious sedation for children undergoing painful procedures in the emergency department.
Topics: Capnography; Carbon Dioxide; Child; Chlorpromazine; Conscious Sedation; Drug Combinations; Emergency | 1997 |
Patient-controlled epidural analgesia after caesarean section using meperidine.
Topics: Adjuvants, Anesthesia; Adult; Analgesia, Patient-Controlled; Anesthesia, Epidural; Anesthesia, Obste | 1997 |
The analgesic effect of fentanyl, morphine, meperidine, and lidocaine in the peripheral veins: a comparative study.
Topics: Adult; Analgesics; Double-Blind Method; Female; Fentanyl; Humans; Injections, Intravenous; Lidocaine | 1998 |
Patient-controlled versus staff-controlled analgesia with pethidine after allogeneic bone marrow transplantation.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Bone Marrow Transplantation; Dose-Response | 1998 |
Patients willing to try colonoscopy without sedation: associated clinical factors and results of a randomized controlled trial.
Topics: Analgesics, Opioid; Colonoscopy; Conscious Sedation; Female; Humans; Hypnotics and Sedatives; Male; | 1999 |
Effects of tramadol and meperidine on respiration, plasma catecholamine concentrations, and hemodynamics.
Topics: Adult; Analgesics, Opioid; Blood Pressure; Catecholamines; Cross-Over Studies; Double-Blind Method; | 1999 |
Intramuscular opioids for maternal pain relief in labour: a randomised controlled trial comparing pethidine with diamorphine.
Topics: Analgesics, Opioid; Double-Blind Method; Female; Heroin; Humans; Injections, Intramuscular; Meperidi | 1999 |
The effect of pentoxifiline on post-injury hyperalgesia in rats and postoperative pain in patients.
Topics: Adult; Animals; Cholecystectomy; Formaldehyde; Humans; Hyperalgesia; Injections, Intraperitoneal; In | 2000 |
Prophylactic metoclopramide is unnecessary with intravenous analgesia in the ED.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Analgesics, Opioid; Antiemetics; Double-Blind | 2000 |
Remifentanil versus meperidine for monitored anesthesia care: a comparison study in older patients undergoing ambulatory colonoscopy.
Topics: Adjuvants, Anesthesia; Aged; Ambulatory Care; Analgesics, Opioid; Anesthetics, Intravenous; Anxiety; | 2001 |
Preinsertion local anesthesia at the trocar site improves perioperative pain and decreases costs of laparoscopic cholecystectomy.
Topics: Abdominal Muscles; Anesthesia, Local; Bupivacaine; Cholecystectomy, Laparoscopic; Cholelithiasis; Co | 2001 |
Anxiolytic premedication reduces preoperative anxiety and pain during oocyte retrieval. A randomized double-blinded placebo-controlled trial.
Topics: Adult; Analgesics, Opioid; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Female; Humans; Meperi | 2002 |
Effect of magnetic endoscope imaging on patient tolerance and sedation requirements during colonoscopy: a randomized controlled trial.
Topics: Adult; Analgesia, Patient-Controlled; Colonoscopes; Colonoscopy; Female; Humans; Hypnotics and Sedat | 2002 |
Effect of magnetic endoscope imaging on patient tolerance and sedation requirements during colonoscopy: a randomized controlled trial.
Topics: Adult; Analgesia, Patient-Controlled; Colonoscopes; Colonoscopy; Female; Humans; Hypnotics and Sedat | 2002 |
Effect of magnetic endoscope imaging on patient tolerance and sedation requirements during colonoscopy: a randomized controlled trial.
Topics: Adult; Analgesia, Patient-Controlled; Colonoscopes; Colonoscopy; Female; Humans; Hypnotics and Sedat | 2002 |
Effect of magnetic endoscope imaging on patient tolerance and sedation requirements during colonoscopy: a randomized controlled trial.
Topics: Adult; Analgesia, Patient-Controlled; Colonoscopes; Colonoscopy; Female; Humans; Hypnotics and Sedat | 2002 |
Comparison of anileridine and pethidine in preventing pain responses during nitrous oxide-oxygen anaesthesia.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Anesthesia, Inhalation; Blood Pressure; Carbon Dioxi | 1975 |
A controlled trial of antiemetics in abortion by PGF2alpha and laminaria.
Topics: Abortion, Induced; Adolescent; Adult; Amnion; Analgesics, Opioid; Antiemetics; Clinical Trials as To | 1978 |
Intramuscular diazepam in labour. A double-blind trial in multiparae.
Topics: Clinical Trials as Topic; Diazepam; Female; Humans; Injections, Intramuscular; Labor, Obstetric; Mep | 1977 |
Analgesic treatment with levomepromazine in acute myocardial infarction. A randomized clinical trial.
Topics: Acute Disease; Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Double-Blind Method; Drug Evalu | 1979 |
[Pain relief in childbirth; an analysis of the analgesic effects of transcutaneous nerve stimulation (TNS), pethidine and placebos (author's transl)].
Topics: Afferent Pathways; Analgesia; Electric Stimulation; Female; Humans; Injections, Intravenous; Labor, | 1978 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
The reliability of a linear analogue for evaluating pain.
Topics: Adult; Analysis of Variance; Evaluation Studies as Topic; Female; Humans; Labor, Obstetric; Male; Me | 1976 |
Controlled clinical trial of oral and parenteral nefopam hydrochloride. A novel and potent analgesic drug.
Topics: Adult; Aged; Clinical Trials as Topic; Female; Humans; Male; Meperidine; Middle Aged; Nefopam; Oxazo | 1976 |
Alfentanil/promazine versus meperidine/promazine as a sedative regimens during local analgesia for cataract operation.
Topics: Aged; Alfentanil; Analgesia; Anesthesia, Local; Blood Pressure; Cataract Extraction; Drug Combinatio | 1992 |
Ketorolac for sickle cell vaso-occlusive crisis pain in the emergency department: lack of a narcotic-sparing effect.
Topics: Acute Disease; Adult; Analgesics; Anemia, Sickle Cell; Double-Blind Method; Emergencies; Female; Hum | 1992 |
Inhibition of burn pain by intravenous lignocaine infusion.
Topics: Burns; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infusions, Intraveno | 1991 |
Maternal opinion about analgesia in labour and delivery. A comparison of epidural blockade and intramuscular pethidine.
Topics: Analgesia, Epidural; Anesthesia, Obstetrical; Female; Humans; Injections, Intramuscular; Labor, Obst | 1990 |
Pre-stimulus/post-stimulus relations in EEG spectra and their modulations by an opioid and an antidepressant.
Topics: Adult; Delta Rhythm; Double-Blind Method; Electroencephalography; Evoked Potentials, Somatosensory; | 1989 |
Controlled trial of haem arginate in acute hepatic porphyria.
Topics: Acute Disease; Adolescent; Arginine; Clinical Trials as Topic; Double-Blind Method; Female; Heme; He | 1989 |
Intravenous meperidine during labor: a randomized comparison between nursing- and patient-controlled administration.
Topics: Adult; Anesthesia, Obstetrical; Female; Humans; Infusion Pumps; Labor, Obstetric; Meperidine; Pain; | 1989 |
[Acute pain due to kidney/ureter stones treated with intramuscular Voltaren or Ketogan].
Topics: Adult; Aged; Allylamine; Amines; Analgesics, Opioid; Diclofenac; Drug Combinations; Female; Humans; | 1987 |
Comparison of ketamine and pethidine in experimental and postoperative pain.
Topics: Adult; Female; Humans; Ischemia; Ketamine; Meperidine; Naloxone; Pain; Pain, Postoperative; Visual P | 1989 |
Treatment of pain owing to acute ureteral obstruction with prostaglandin-synthetase inhibitor: a prospective randomized study.
Topics: Adolescent; Adult; Butylscopolammonium Bromide; Clinical Trials as Topic; Cyclooxygenase Inhibitors; | 1986 |
Double-blind comparison of nalbuphine and meperidine in combination with diazepam for intravenous conscious sedation in oral surgery outpatients.
Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anxiety; Diazepam; Double-Blind Method; Female; Humans | 1988 |
Comparative study of meptazinol and pethidine for the relief of pain in labour.
Topics: Adult; Azepines; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Meperidine; Meptazin | 1986 |
Imipramine reduces experimental pain.
Topics: Adult; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Dibenzoxazepines; Double-Blind Me | 1986 |
A double-blind trial of the analgesic properties of physostigmine in postoperative patients.
Topics: Adult; Analgesia; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Kin | 1986 |
A double-blind study comparing meptazinol and pethidine for pain relief in labour.
Topics: Adult; Anesthesia, Obstetrical; Azepines; Double-Blind Method; Female; Humans; Infant, Newborn; Labo | 1987 |
Comparison of the antiemetics metoclopramide and promethazine in labour.
Topics: Clinical Trials as Topic; Consciousness; Double-Blind Method; Female; Humans; Meperidine; Metoclopra | 1985 |
Relief of fain in labour. A controlled double-blind trial comparing pethidine and various phenothiazine derivatives.
Topics: Analgesics; Clinical Trials as Topic; Female; Humans; Hypnotics and Sedatives; Injections, Intramusc | 1967 |
The clinical testing of weak oral analgesics.
Topics: Administration, Oral; Analgesics; Clinical Trials as Topic; Drug Evaluation; Humans; Meperidine; Met | 1974 |
Nasogastric suction in the treatment of alcoholic pancreatitis. A controlled study.
Topics: Acute Disease; Adult; Alcoholism; Amylases; Clinical Enzyme Tests; Clinical Trials as Topic; Drainag | 1974 |
A comparison of pethidine, piritramide and oxycodone in patients with pain following cholecystectomy.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cholecystectomy; Female; Humans; Isonipecotic Acids; Male; | 1973 |
Post-operative pain in the assessment of analgesics in man.
Topics: Analgesics; Aspirin; Clinical Trials as Topic; Humans; Meperidine; Pain; Postoperative Complications | 1969 |
Propoxyphene hydrochloride. A critical review.
Topics: Analgesics; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Female; Headac | 1970 |
Clinical trial comparing pentazocine with pethidine and morphine in severe ischaemic limb pain.
Topics: Adult; Aged; Clinical Trials as Topic; Female; Humans; Ischemia; Male; Meperidine; Middle Aged; Morp | 1971 |
A comparison of pentazocine and pethidine in patients with pain following cholecystectomy.
Topics: Adult; Aged; Blood Pressure; Cholecystectomy; Clinical Trials as Topic; Female; Heart Rate; Humans; | 1971 |
Controlled comparison of the efficacy of fourteen preparations in the relief of postoperative pain.
Topics: Abdomen; Adult; Analgesics; Clinical Trials as Topic; Consciousness; Cyclizine; Humans; Levorphanol; | 1971 |
[Effects of sedatives on postoperative pain].
Topics: Blood Pressure; Chlorpromazine; Clinical Trials as Topic; Humans; Hypnotics and Sedatives; Injection | 1971 |
Analgesic potency of pentazocine and pethidine in post-operative pain.
Topics: Adult; Aged; Clinical Trials as Topic; Evaluation Studies as Topic; Female; Humans; Male; Meperidine | 1971 |
Control of postoperative pain: a comparison of the efficacy and safety of pentazocine, methotrimeprazine, meperidine, and a placebo.
Topics: Clinical Trials as Topic; Female; Humans; Male; Meperidine; Methotrimeprazine; Pain; Pentazocine; Pl | 1970 |
Pentazocine, pethidine and placebo for postoperative pain. An assessment by means of ventilatory measurements and subjective evaluation.
Topics: Abdomen; Adult; Aged; Analgesia; Attitude; Female; Humans; Male; Meperidine; Middle Aged; Nausea; Pa | 1972 |
Failure of systemic analgesic agents to alter the absolute sensory threshold for the simple detection of pain.
Topics: Aspirin; Clinical Trials as Topic; Ethanol; Hot Temperature; Humans; Meperidine; Neurophysiology; Pa | 1965 |
[Experiences with faustan for the prevention of muscle pain from succinyl choline administration].
Topics: Atropine; Diazepam; Female; Humans; Male; Meperidine; Muscles; Pain; Succinylcholine | 1970 |
A comparison of the analgesics pentazocine and pethilorfan in the relief of pain during labour.
Topics: Adult; Female; Humans; Labor, Obstetric; Levallorphan; Meperidine; Middle Aged; Pain; Pentazocine; P | 1971 |
Other Studies
308 other studies available for meperidine and Ache
| Article | Year |
|---|---|
Evaluation of opioid consumption trends for pain in Taiwan and comparison with neighboring Asian countries.
Topics: Analgesics, Opioid; Codeine; Fentanyl; Humans; Meperidine; Morphine; Pain; Taiwan | 2022 |
Comparison of analgesic consumption of hemophilic and non-hemophilic patients in knee arthroplasty.
Topics: Analgesics; Arthroplasty, Replacement, Knee; Factor VIII; Hemophilia A; Humans; Joint Diseases; Mepe | 2022 |
An analytical approach to determining pethidine: An investigation of 18 patients' urine.
Topics: Analgesics, Opioid; Biological Assay; Body Fluids; Humans; Meperidine; Pain | 2023 |
Declines and pronounced regional disparities in meperidine use in the United States.
Topics: Analgesics, Opioid; Drug Utilization; Humans; Meperidine; Obesity; Pain; Practice Patterns, Physicia | 2021 |
Nursing a critically ill tetanus patient in an intensive care unit in Zambia.
Topics: Analgesics, Opioid; Anti-Infective Agents; Anticonvulsants; Back Pain; Critical Care Nursing; Critic | 2017 |
Pain relief during labour: challenging the use of intramuscular pethidine.
Topics: Female; Humans; Injections, Intramuscular; Labor, Obstetric; Meperidine; Pain; Pain Management; Preg | 2018 |
Trends in the consumption of opioids for the treatment of severe pain in Europe, 1990-2016.
Topics: Analgesics, Opioid; Europe; European Union; Fentanyl; Humans; Hydromorphone; Meperidine; Morphine; O | 2019 |
Remifentanil patient-controlled analgesia (PCA) in labour - in the eye of the storm.
Topics: Analgesia, Obstetrical; Analgesia, Patient-Controlled; Female; Humans; Labor, Obstetric; Meperidine; | 2019 |
Patterns of opioid use (codeine, morphine or meperidine) in the Canadian population over time: analysis of the Longitudinal National Population Health Survey 1994-2011.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Canada; Child; Chronic Disease; Codeine; Female; Health | 2019 |
[Pain in connection with colonoscopy in Norway].
Topics: Aged; Analgesics; Colonoscopy; Drug Utilization; Female; Hospitals; Humans; Hypnotics and Sedatives; | 2013 |
Post-sedation events in children sedated for dental care.
Topics: Adjuvants, Anesthesia; Anesthesia, Dental; Child; Child Behavior; Child, Preschool; Conscious Sedati | 2013 |
Efficacy of intramuscular meperidine hydrochloride versus placebo in experimental foot lameness in horses.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Foot Diseases; Horse Diseases; Horses; Lameness, A | 2013 |
Combination of paracetamol or ketamine with meperidine enhances antinociception.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Dose-Response Relationship, Dr | 2016 |
Pain relief during minor procedures: a challenge for gynaecologists.
Topics: Anesthesia, Obstetrical; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Endometrium; Female; Human | 2015 |
DEMEROL ANALGESIA IN OBSTETRICS.
Topics: Analgesia; Female; Humans; Labor, Obstetric; Meperidine; Obstetrics; Pain; Pain Management; Pharmace | 1946 |
Post-procedure surveillance in liver biopsy: how long is long enough?
Topics: Adult; Aged; Analgesics, Opioid; Biopsy; Central Nervous System Depressants; Continuity of Patient C | 2008 |
Edema of the uvula and glottis associated with demerol-scopolamine analgesia.
Topics: Analgesia; Edema; Glottis; Meperidine; Pain; Pain Management; Scopolamine; Uvula | 1948 |
Meperidine for acute sickle cell crisis: what is the rationale?
Topics: Analgesics, Opioid; Anemia, Sickle Cell; Humans; Meperidine; Pain | 2008 |
Evaluation of the P-glycoprotein (Abcb1) affinity status of a series of morphine analogs: comparative study with meperidine analogs to identify opioids with minimal P-glycoprotein interactions.
Topics: Analgesics, Opioid; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub | 2009 |
Tracking the effects of policy changes in prescribing analgesics in one emergency department: a 10-year analysis.
Topics: Administration, Oral; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Emergencies; Emer | 2010 |
Where has all the meperidine gone?
Topics: Analgesics, Opioid; Humans; Meperidine; Pain | 2010 |
The comparison of birth outcomes and birth experiences of low-risk women in different sized midwifery practices in the Netherlands.
Topics: Adolescent; Adult; Analgesics, Opioid; Cesarean Section; Female; Home Childbirth; Humans; Incidence; | 2010 |
[Acute transverse myelitis: treatment of pain].
Topics: Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Female; Humans; Meperidine; Myelitis, Transverse | 2010 |
Demerol-scopolamine analgesia in labor.
Topics: Analgesia; Anesthesia; Anesthesia, Obstetrical; Curare; Female; Gynecology; Humans; Meperidine; Nort | 1947 |
Demerol for analgesia in obstetrics.
Topics: Analgesia; Anesthesia; Meperidine; Obstetrics; Pain; Pain Management | 1947 |
Effects of opioids in the formalin test in the Speke's hinged tortoise (Kinixy's spekii).
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Female; Male; Meperidine; Morphine; N | 2010 |
The relief of pain in labour with demerol.
Topics: Anesthesia; Anesthesia, Obstetrical; Anesthesiology; Female; Gynecology; Humans; Labor, Obstetric; M | 1946 |
Anti-inflammatory and analgesic activity of different extracts of Commiphora myrrha.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Commiphora; Dinoprosto | 2011 |
Attitude and knowledge of physicians about cancer pain management: young doctors of South Korea in their early career.
Topics: Adrenal Cortex Hormones; Adult; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Attitude | 2011 |
The burden of endoscopic retrograde cholangiopancreatography (ERCP) performed with the patient under conscious sedation.
Topics: Aged; Cholangiopancreatography, Endoscopic Retrograde; Conscious Sedation; Female; Fentanyl; Humans; | 2012 |
A comparison of early sucking dynamics during breastfeeding after cesarean section and vaginal birth.
Topics: Adult; Analgesia, Epidural; Breast Feeding; Cesarean Section; Delivery, Obstetric; Female; Humans; I | 2013 |
Can a pain management and palliative care curriculum improve the opioid prescribing practices of medical residents?
Topics: Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chronic | 2002 |
[Long-memory of labor pain].
Topics: Analgesia, Obstetrical; Analgesics, Opioid; Female; Humans; Labor, Obstetric; Memory; Mental Recall; | 2002 |
[Measurement of postoperative pain: analysis of the sensitivity of various self-evaluation instruments].
Topics: Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Humans | 2003 |
[Analgesia with demerol in the Maternité de Chancerelles].
Topics: Analgesia; Female; Humans; Labor, Obstetric; Meperidine; Pain; Pain Management; Pregnancy | 1952 |
Meperidine hydrochloride used intravenously before gastroscopy; preliminary report.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Gastroscopy; Meperidine; Pain; Pain Management | 1953 |
[Intravenous procaine and dolantin in anesthesia and postoperative analgesia].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Humans; Meperidine; Pain; Pain Management; Postoper | 1953 |
An evaluation of obstetrical analgesia.
Topics: Analgesia; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia; Anesthesia and Analgesia; Barbitu | 1954 |
The analgesic effectiveness of codeine and meperidine (demerol).
Topics: Analgesia; Analgesics; Anesthesia; Anesthesia and Analgesia; Codeine; Humans; Meperidine; Pain; Pain | 1954 |
Drug addiction and other considerations in the management of pain with narcotic drugs.
Topics: Behavior, Addictive; Humans; Meperidine; Methadone; Morphine Dependence; Morphine Derivatives; Narco | 1957 |
Drug addiction and other considerations in the management of pain with narcotic drugs.
Topics: Behavior, Addictive; Humans; Meperidine; Methadone; Morphine Dependence; Morphine Derivatives; Narco | 1957 |
Drug addiction and other considerations in the management of pain with narcotic drugs.
Topics: Behavior, Addictive; Humans; Meperidine; Methadone; Morphine Dependence; Morphine Derivatives; Narco | 1957 |
Drug addiction and other considerations in the management of pain with narcotic drugs.
Topics: Behavior, Addictive; Humans; Meperidine; Methadone; Morphine Dependence; Morphine Derivatives; Narco | 1957 |
[Tests of neurolytic drugs in neurosurgical operations in children].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Brain; Child; Chlorpromazine; Humans; Meperidine; P | 1957 |
Levallorphan and meperidine in anesthesia; study of effects in supplementation of nitrous oxide-oxygenthiopental sodium anesthesia.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesia, Inhalation; Levallorphan; Meperidine; M | 1958 |
Meperidine-levallorphan in anesthesia; study of usefulness of such mixtures in supplementation of nitrous oxide-oxygen-thiopental anesthesia.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesia, Inhalation; Anesthesiology; Levallorpha | 1958 |
Intravenous sedation in cataract surgery.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Cataract; Cataract Extraction; Chlorpromazine; Huma | 1958 |
A comparison of the analgesic efficacy of d-propoxyphene (darvon) and meperidine (demerol).
Topics: Analgesia; Analgesics; Analgesics, Non-Narcotic; Anesthesia; Anesthesia and Analgesia; Antipyretics; | 1958 |
A comparison in man of the effects of promethazine, secobarbital, and meperidine alone and in combination on certain respiratory functions and for use in preanesthetic medication.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Barbiturates; Humans; Meperidine; Pain; Preanesthet | 1958 |
Comparative effects of analgesics on pain threshold, respiratory frequency and gastrointestinal propulsion.
Topics: Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Antipyretics; Cell Respiration; C | 1959 |
Pethidine and levallorphan; their combined use for premedication.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Levallorphan; Meperidine; Morphine; Pain; Pain Mana | 1959 |
[Use of the meprobamate-promethazine-meperidine combination in preanesthesia].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Humans; Meperidine; Meprobamate; Pain; Pain Managem | 1959 |
Alterations in response to somatic pain associated with anaesthesia. I. An evaluation of a method of analgesimetry.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Humans; Meperidine; Nociceptive Pain; Ozone; Pain; | 1960 |
Demerol as an anesthetic agent used in 9,000 surgical cases.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesia, General; Anesthetics; Humans; Meperidin | 1960 |
Synergistic basal narcosedation. A basic technique employing promethazine, meperidine, and secobarbital.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Meperidine; Pain; Pain Management; Promethazine; Se | 1960 |
The postoperative use of demerol-lotusate tablets in orthopedic surgery.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Barbiturates; Meperidine; Orthopedics; Pain; Tablet | 1959 |
Local anesthesia in ophthalmology.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesia, Local; Anesthesiology; Anesthetics, Loc | 1962 |
Analgesia in electromyography.
Topics: Analgesia; Electromyography; Humans; Meperidine; Methadone; Pain; Pain Management; Promethazine | 1963 |
[On a new method in the pharmacological study of the reaction to pain].
Topics: Dextromoramide; Humans; Meperidine; Morphine; Pain; Research | 1963 |
BETA-(N-PYRROLIDYL)-BUTYROANILID (WS 10): ITS SUBACUTE TOXICITY, INFLUENCE ON MORPHINE ANALGESIA IN THE RAT AND MORPHINE ANALGESIA AND RESPIRATORY DEPRESSION IN THE RABBIT.
Topics: Analgesia; Analgesics; Analgesics, Non-Narcotic; Anilides; Antipyretics; Aspirin; Codeine; Meperidin | 1963 |
[ON THE CONTROL OF PAIN IN CANCER].
Topics: Aminopyrine; Humans; Meperidine; Neoplasms; Pain | 1963 |
EVALUATION OF OPIATES FOR PAIN AND PREMEDICATION.
Topics: Analgesics, Opioid; Humans; Hydromorphone; Meperidine; Morphine; Pain; Preoperative Care; Toxicology | 1963 |
[OPIATE ANTAGONISTS AND PAIN CONTROL].
Topics: Analgesia; Humans; Meperidine; Narcotic Antagonists; Pain; Pain Management | 1963 |
[MODERN ANALGESIA SUB PARTU WITH LORFALGYL].
Topics: Analgesia; Anesthesia; Anesthesia, Obstetrical; Humans; Meperidine; Narcotic Antagonists; Pain; Pain | 1963 |
THE CONTROL OF SEVERE PAIN WITH ORAL OXYMORPHONE HYDROCHLORIDE.
Topics: Adolescent; Geriatrics; Humans; Hydromorphone; Meperidine; Oxymorphone; Pain; Toxicology | 1963 |
[THE CURRENT STATUS OF PAIN CONTROL AND WOUND TREATMENT].
Topics: Aminopyrine; Anti-Allergic Agents; Histamine H1 Antagonists; Humans; Meperidine; Pain; Pain Manageme | 1963 |
DOUBLE BLIND TRIAL OF DEXTROMORAMIDE, METHADONE AND PETHIDINE IN THE TREATMENT OF SEVERE PAIN.
Topics: Dextromoramide; Double-Blind Method; Humans; Meperidine; Methadone; Pain; Toxicology | 1964 |
ANAESTHESIA AND ANALGESIA IN DOMICILIARY MIDWIFERY.
Topics: Analgesia; Anesthesia; Anesthesia, Conduction; Anesthesia, General; Anesthesia, Inhalation; Anesthes | 1964 |
ANALGESICS FOR THE RELIEF OF PAIN. I. NARCOTIC ANALGESICS.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Codeine; Humans; Hydromorphone; Meperidine; Meth | 1964 |
A COMPARISON OF DEXTRO-PROPOXYPHENE HYDROCHLORIDE AND MEPERIDINE HYDROCHLORIDE.
Topics: Analgesia; Analgesics; Arachnoid; Central Nervous System; Dextropropoxyphene; Humans; Meningitis; Me | 1964 |
A CLINICAL ANALYSIS OF PANCREATITIS. (A REVIEW OF 54 CASES).
Topics: Adolescent; Ampulla of Vater; Child; Diet; Diet Therapy; Humans; Infant; Meperidine; Pain; Pancreati | 1964 |
[RESEARCH ON THE MECHANISM OF ACTION OF CERTAIN CENTRAL ANALGESICS (MORPHINE, PETHIDINE AND DEXTROMORAMIDE)].
Topics: Analgesics; Dextromoramide; Hunger; Meperidine; Morphine; Pain; Parasympatholytics; Pharmacology; Ra | 1964 |
CAUSE AND EFFECT IN IRUKANDJI STINGINGS.
Topics: Animals; Aspirin; Australia; Bites and Stings; Child; Cnidaria; Drug Therapy; Erythema; Gastroenteri | 1964 |
COMPARISON OF POTENCY OF INJECTABLE MEPERIDINE AND PROMETHAZINE-MEPERIDINE CAPSULES IN POSTOPERATIVE PAIN.
Topics: Analgesia; Biomedical Research; Capsules; Humans; Injections, Intramuscular; Meperidine; Pain; Pain | 1964 |
STUDIES OF THE HUMAN THALAMUS: IV. EVOKED RESPONSES.
Topics: Biomedical Research; Brain; Electric Stimulation; Electroencephalography; Electrophysiology; Facial | 1964 |
NARCOTIC AND NON-NARCOTIC ANALGESICS WHICH BLOCK VISCERAL PAIN EVOKED BY INTRA-ARTERIAL INJECTION OF BRADYKININ AND OTHER ALGESIC AGENTS.
Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Anilides; Antipyretics; Aspirin; Bradykinin; Dogs | 1964 |
NARCOTIC AND NON-NARCOTIC ANALGESICS WHICH BLOCK VISCERAL PAIN EVOKED BY INTRA-ARTERIAL INJECTION OF BRADYKININ AND OTHER ALGESIC AGENTS.
Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Anilides; Antipyretics; Aspirin; Bradykinin; Dogs | 1964 |
NARCOTIC AND NON-NARCOTIC ANALGESICS WHICH BLOCK VISCERAL PAIN EVOKED BY INTRA-ARTERIAL INJECTION OF BRADYKININ AND OTHER ALGESIC AGENTS.
Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Anilides; Antipyretics; Aspirin; Bradykinin; Dogs | 1964 |
NARCOTIC AND NON-NARCOTIC ANALGESICS WHICH BLOCK VISCERAL PAIN EVOKED BY INTRA-ARTERIAL INJECTION OF BRADYKININ AND OTHER ALGESIC AGENTS.
Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Anilides; Antipyretics; Aspirin; Bradykinin; Dogs | 1964 |
THE USE OF MEPERGAN FOR RELIEF OF PAIN IN GYNECOLOGIC TUMOR PATIENTS.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Biomedical Research; Female; Genital Neoplasms, | 1964 |
POSTOPERATIVE PAIN.
Topics: Analgesia; Fear; Humans; Meperidine; Morphine; Nurse-Patient Relations; Pain; Pain Management; Pain, | 1964 |
HEMORRHOIDECTOMY WITHOUT PAIN.
Topics: Anesthesia; Colorectal Surgery; Hemorrhoidectomy; Hemorrhoids; Humans; Meperidine; Meprobamate; Pain | 1964 |
SUPPRESSION OF SECRETION AND CONTROL OF PAIN IN PANCREATITIS.
Topics: Acetazolamide; Adrenal Cortex Hormones; Analgesia; Dextrans; Drug Therapy; Epinephrine; Humans; Intu | 1964 |
ACUTE CERVICAL PAIN ASSOCIATED WITH RETROPHARYNGEAL CALCIUM DEPOSIT. A CASE REPORT.
Topics: Axis, Cervical Vertebra; Calcinosis; Calcium; Cervical Atlas; Drug Therapy; Humans; Meperidine; Neck | 1964 |
THE INHIBITION OF ANALGESIA IN MICE BY THIOPENTONE.
Topics: Analgesia; Animals; Codeine; Meperidine; Mice; Morphine; Pain; Pain Management; Pharmacology; Resear | 1964 |
COMPARISON OF ORAL PROMETHAZINE-MEPERIDINE WITH INJECTABLE MEPERIDINE FOR RELIEF OF POSTOPERATIVE PAIN.
Topics: Biomedical Research; Capsules; Dosage Forms; Drug Therapy; Genital Diseases, Female; Humans; Injecti | 1965 |
SITE OF ACTION OF NARCOTIC AND NON-NARCOTIC ANALGESICS DETERMINED BY BLOCKING BRADYKININ-EVOKED VISCERAL PAIN.
Topics: Amphetamine; Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Aspirin; Azepines; Bradyki | 1964 |
SITE OF ACTION OF NARCOTIC AND NON-NARCOTIC ANALGESICS DETERMINED BY BLOCKING BRADYKININ-EVOKED VISCERAL PAIN.
Topics: Amphetamine; Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Aspirin; Azepines; Bradyki | 1964 |
SITE OF ACTION OF NARCOTIC AND NON-NARCOTIC ANALGESICS DETERMINED BY BLOCKING BRADYKININ-EVOKED VISCERAL PAIN.
Topics: Amphetamine; Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Aspirin; Azepines; Bradyki | 1964 |
SITE OF ACTION OF NARCOTIC AND NON-NARCOTIC ANALGESICS DETERMINED BY BLOCKING BRADYKININ-EVOKED VISCERAL PAIN.
Topics: Amphetamine; Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Aspirin; Azepines; Bradyki | 1964 |
[ANALGESIA FOLLOWING GYNECOLOGICAL OPERATIONS].
Topics: Analgesia; Drug Therapy; Female; Genital Diseases, Female; Humans; Meperidine; Methadone; Pain; Phen | 1965 |
ANALGESIA IN MYOCARDIAL INFARCTION: DOUBLE-BLIND COMPARISON OF PIMINODINE AND MORPHINE.
Topics: Analgesia; Arteriosclerosis; Biomedical Research; Double-Blind Method; Drug Therapy; Geriatrics; Hum | 1965 |
[ON SPASMOLYSIS AND ANALGESIA IN UROLOGY].
Topics: Aminopyrine; Analgesia; Drug Therapy; Humans; Meperidine; Pain; Pain Management; Urologic Diseases; | 1964 |
SINGLE-INJECTION CAUDAL EPIDURAL ANALGESIA.
Topics: Analgesia, Epidural; Anesthesia; Anesthesia, Spinal; Biomedical Research; Epinephrine; Humans; Lidoc | 1965 |
PENTAZOCINE--A NEW NONADDICTING ANALGESIC. A DOUBLE-BLIND EVALUATION IN POSTOPERATIVE PAIN.
Topics: Analgesics; Analgesics, Non-Narcotic; Anesthesia; Antipyretics; Double-Blind Method; Drug Therapy; G | 1965 |
THE EFFICACY OF PLACEBO ON PAIN PERCEPTION THRESHOLD.
Topics: Alphaprodine; Biomedical Research; Blood Pressure; Dental Pulp; Electric Stimulation; Heart Rate; Hu | 1965 |
[Analgetic effect of morphine, dolsin and mecodin in various ways of application; a pharmacological study].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Meperidine; Methadone; Morphine; Pain; Pain Managem | 1955 |
Anaesthesia with leostesin (lidocaine) and pethidine in bronchoscopy.
Topics: Aged; Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesiology; Bronchoscopy; Humans; Lidocai | 1959 |
[Anesthesia with leostesin (lidocaine) and pethidine in bronchoscopy].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Bronchoscopy; Humans; Lidocaine; Meperidine; Pain; | 1959 |
Continuous meperidine drip in geriatric anesthesia.
Topics: Aged; Aged, 80 and over; Analgesia; Anesthesia; Anesthesia and Analgesia; Geriatrics; Humans; Meperi | 1962 |
Clinical assessment of analgesic drugs. (1). Initial trial.
Topics: Analgesia; Analgesics; Anesthesia; Anesthesia and Analgesia; Meperidine; Pain; Pain Management | 1962 |
Removing meperidine from the health-system formulary--frequently asked questions.
Topics: Analgesics, Opioid; Chemistry, Pharmaceutical; Formularies, Hospital as Topic; Hospitals, University | 2002 |
2003 LeTourneau Award. Freedom from pain. Establishing a constitutional right to pain relief.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Civil Rights; Female; Humans; Male; Meperidine; | 2003 |
Art and medicine 2: Pethidine by Dr Matthew Clark.
Topics: Analgesics, Opioid; Humans; Medicine in the Arts; Meperidine; Pain; Sculpture | 2004 |
Continuous intravenous drip of meperidine and scopolamine for relief of pains of labor.
Topics: Female; Humans; Infusions, Intravenous; Labor, Obstetric; Meperidine; Pain; Pregnancy; Scopolamine; | 1952 |
Altering meperidine prescribing patterns in a university teaching hospital.
Topics: Analgesics, Opioid; Analysis of Variance; Drug Utilization Review; Education, Medical, Continuing; H | 2004 |
Meperidine-induced seizure after revision hip arthroplasty.
Topics: Acetabulum; Adult; Analgesics; Arthroplasty, Replacement, Hip; Female; Hip Dislocation; Humans; Mepe | 2004 |
Determinants of prescribing meperidine compared to morphine in hospitalized patients.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Chi-Square Distribution; Female; Hospitals; Humans; Male | 2004 |
A shift from demerol (meperidine) to dilaudid (hydromorphone) improves pain control and decreases admissions for patients in sickle cell crisis.
Topics: Anemia, Sickle Cell; Clinical Protocols; Emergency Service, Hospital; Humans; Hydromorphone; Meperid | 2004 |
Big black spider bite from the desert region of Western Australia.
Topics: Adult; Analgesics, Opioid; Angiolipoma; Diagnosis, Differential; Humans; Male; Meperidine; Opioid-Re | 2005 |
Simplifying prehospital analgesia. Why certain medications should or should not be used for pain management in the field.
Topics: Analgesics; Anesthetics, Combined; Butorphanol; Emergency Medical Services; Emergency Medical Techni | 2005 |
Antinociceptive activity of Vitex-negundo Linn leaf extract.
Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Aspirin; Dose-Response Relationship, Drug; Drug Inte | 2005 |
Pethidine in emergency departments; promoting evidence-based prescribing.
Topics: Acute Disease; Analgesics, Opioid; Australia; Drug Utilization Review; Emergency Service, Hospital; | 2006 |
Drug therapy in dental practice: nonopioid and opioid analgesics.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2005 |
Meperidine to manage pain related to diverticular disease.
Topics: Analgesics, Opioid; Diverticulosis, Colonic; Humans; Meperidine; Morphine; Pain | 2006 |
Hospital admissions for acute painful crisis in Trinidad and Tobago. Are the British Committee for Standards in Haematology (BCSH) guidelines applicable?
Topics: Adolescent; Adult; Analgesics, Opioid; Anemia, Sickle Cell; Female; Guideline Adherence; Hospitaliza | 2006 |
Stability and compatibility of a meperidine-clonidine mixture in portable pump reservoirs for the management of cancer pain syndromes.
Topics: Analgesics; Analgesics, Opioid; Clonidine; Complex Mixtures; Drug Combinations; Drug Stability; Huma | 2006 |
Adequacy of pain relief in closed manipulative reduction of fracture and dislocation.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Analgesia; Child; Cross-Sectional Studies; Diazepam; | 2006 |
Multifaceted education initiative minimizes pethidine prescribing in the emergency department.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Australia; Drug Prescriptions; Drug Utilization; | 2007 |
Eradicating analgesic use of meperidine in a hospital.
Topics: Analgesics, Opioid; Drug Utilization Review; Hospitals; Humans; Meperidine; Pain; Personnel, Hospita | 2007 |
Intraoperative analgesia for day-care surgery: practice trends.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anal | 2007 |
Effects of rat/mouse hemokinin-1, a mammalian tachykinin peptide, on the antinociceptive activity of pethidine administered at the peripheral and supraspinal level.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Behavior, Animal; Disease Models, Animal; Dose-Re | 2007 |
Meperidine prolongs lidocaine caudal epidural anaesthesia in the horse.
Topics: Adjuvants, Anesthesia; Anesthesia, Epidural; Animals; Drug Synergism; Female; Horses; Lidocaine; Mal | 2008 |
Edema of the uvula following demerol-hyoscine analgesia.
Topics: Analgesia; Edema; Humans; Meperidine; Pain; Pain Management; Scopolamine; Uvula | 1949 |
Use of meperidine as the analgesic of choice in treating pain from acute painful sickle cell crisis.
Topics: Analgesics, Opioid; Anemia, Sickle Cell; Humans; Meperidine; Pain | 2008 |
Why meperidine should not make a comeback in treating patients with sickle cell disease.
Topics: Analgesics, Opioid; Anemia, Sickle Cell; Humans; Meperidine; Pain | 2008 |
Meperidine for acute sickle cell pain in the emergency department: revisited controversy.
Topics: Analgesics, Opioid; Anemia, Sickle Cell; Emergency Service, Hospital; Half-Life; Humans; Meperidine; | 2008 |
Action of various new analgesic drugs on the human common bile duct.
Topics: Analgesics; Common Bile Duct; Dextromoramide; Dextropropoxyphene; Humans; Injections, Intramuscular; | 1967 |
Methotrimeprazine (Levoprome)--a potent analgesic.
Topics: Humans; Meperidine; Methotrimeprazine; Morphine; Pain; Preanesthetic Medication | 1967 |
Endorphins and on-demand pain relief.
Topics: Analgesia; Endorphins; Humans; Meperidine; Pain; Self Administration | 1980 |
Studies in the primate on the analgetic effects associated with intrathecal actions of opiates, alpha-adrenergic agonists and baclofen.
Topics: Adrenergic alpha-Agonists; Analgesia; Animals; Avoidance Learning; Baclofen; Behavior, Animal; Cats; | 1981 |
Potentiation of nitrogen mustard toxicity by narcotic analgesic.
Topics: Analgesics, Opioid; Animals; Cyclophosphamide; Drug Synergism; Female; Male; Mechlorethamine; Meperi | 1981 |
A patient looks at pain and analgesia.
Topics: Analgesics, Opioid; Drug Administration Schedule; Humans; Meperidine; Morphine; Pain | 1982 |
Analgesic efficacy and pharmacokinetic evaluation of meperidine and hydroxyzine, alone and in combination.
Topics: Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Double-Blind Method; Dru | 1983 |
Non-opioid pathways suppress pain in humans.
Topics: Analgesia; Electric Stimulation Therapy; Humans; Meperidine; Osteoarthritis; Pain; Pain Management; | 1981 |
Influence of medication, pain and progress in labour on plasma beta-endorphin-like immunoreactivity.
Topics: Adolescent; Adult; Anesthesia, Inhalation; Anesthesia, Obstetrical; beta-Endorphin; Endorphins; Fema | 1982 |
Attenuation of pethidine-induced antinociception by zimelidine, an inhibitor of 5-hydroxytryptamine reuptake.
Topics: Animals; Brompheniramine; Drug Interactions; Male; Meperidine; Morphine; Pain; Pyridines; Rats; Reac | 1980 |
[Characterization of the effect of analgesics on the assessment of experimental pain in man. Pethidine and tramadol in a double-blind comparison].
Topics: Adult; Cyclohexanols; Double-Blind Method; Female; Galvanic Skin Response; Humans; Hypnotics and Sed | 1984 |
[Principles of preclinical pain treatment of emergency patients].
Topics: Analgesics; Anesthesia, Inhalation; Anesthesia, Local; Emergencies; First Aid; Humans; Ketamine; Mep | 1984 |
The formalin test: a tonic pain model in the primate.
Topics: Animals; Behavior, Animal; Chronic Disease; Disease Models, Animal; Female; Formaldehyde; Hand; Maca | 1984 |
The intracutaneous stimulus: a new pain model for algesimetric studies.
Topics: Adult; Analgesics; Differential Threshold; Electric Stimulation; Electroencephalography; Evoked Pote | 1984 |
[Peridural meperidine in the treatment of pain in acute myocardial infarction].
Topics: Adult; Aged; Anesthesia, Epidural; Female; Hemodynamics; Humans; Male; Meperidine; Middle Aged; Myoc | 1984 |
Opioid drugs cause bile duct obstruction during hepatobiliary scans.
Topics: Acute Disease; Adult; Biliary Tract; Cholecystitis; Cholestasis; Female; Humans; Hydroxyzine; Imino | 1984 |
The efficacy of oral vs. IM meperidine.
Topics: Administration, Oral; Adult; Humans; Injections, Subcutaneous; Meperidine; Pain | 1984 |
Chronic pain and the risks of psychotropics.
Topics: Amitriptyline; Chronic Disease; Female; Fluphenazine; Heart Failure; Humans; Meperidine; Middle Aged | 1984 |
Analgetic effects of indomethacin (Confortid) compared to Ketogin in patients with acute cholecystitis.
Topics: Acute Disease; Allylamine; Amines; Analgesics; Cholecystitis; Drug Combinations; Female; Humans; Ind | 1983 |
The antinociceptive effect of ketobemidone in comparison with Ketogin.
Topics: Allylamine; Amines; Analgesics; Animals; Benzoquinones; Drug Combinations; Electroshock; Male; Meper | 1983 |
Relative analgesic potency of intramuscular heroin and morphine in cancer patients with postoperative pain and chronic pain due to cancer.
Topics: Adult; Aged; Analgesics; Chronic Disease; Female; Heroin; Humans; Injections, Intramuscular; Levorph | 1981 |
Experience with self-administered pethidine with special reference to the general practitioner obstetric unit.
Topics: Anesthesia, Intravenous; Anesthesia, Obstetrical; Apgar Score; Family Practice; Female; Humans; Infa | 1983 |
Abnormal labour and pain relief.
Topics: Adolescent; Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Female; Humans; Labor Presentation | 1981 |
The duration of effect of maternally administered meperidine on neonatal neurobehavior.
Topics: Behavior; Female; Humans; Infant, Newborn; Meperidine; Nervous System; Neurologic Examination; Obste | 1982 |
The antinociceptive effects of epidural opiates in the cat: studies of the pharmacology and the effects of lipophilicity in spinal analgesia.
Topics: Animals; Cats; Dose-Response Relationship, Drug; Epidural Space; Female; Fentanyl; Lipids; Male; Mep | 1982 |
[Pain caused by herpes zoster].
Topics: Adrenochrome; Antiviral Agents; Carbamazepine; Electrogalvanism, Intraoral; Fluorescein; Fluorescein | 1982 |
Peridural meperidine in humans: analgesic response, pharmacokinetics, and transmission into CSF.
Topics: Adult; Aged; Catheterization; Epidural Space; Female; Humans; Kinetics; Male; Meperidine; Middle Age | 1981 |
Problems with the use of oxycodone compound in patients with chronic pain.
Topics: Aspirin; Caffeine; Chronic Disease; Codeine; Dextropropoxyphene; Drug Combinations; Female; Humans; | 1981 |
Potentiation of presynaptic inhibition of nociceptive pathways as a mechanism for analgesia.
Topics: Analgesics; Animals; Bradykinin; Cats; Electric Stimulation; Meperidine; Nerve Endings; Neural Inhib | 1980 |
Relationship between blood meperidine concentrations and analgesic response: a preliminary report.
Topics: Adult; Analgesia; Dose-Response Relationship, Drug; Extraversion, Psychological; Female; Humans; Mal | 1980 |
Painful lessons: opioids, iatrogenic dependence and professional standards.
Topics: Drug Utilization; Humans; Iatrogenic Disease; Meperidine; Opioid-Related Disorders; Pain | 1995 |
Palliative/hospice care in Poland.
Topics: Drug Utilization; Forecasting; Hospices; Humans; Meperidine; Morphine; Neoplasms; Organizational Obj | 1993 |
[Patient-controlled analgesia with pethidine in acute intermittent porphyria].
Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Female; Humans; Meperidine; Middle Aged; Pain; Po | 1995 |
Altered responses to medications exposed to excessive temperatures during shipping.
Topics: Chronic Disease; Diazepam; Drug Stability; Drug Storage; Female; Hot Temperature; Humans; Meperidine | 1995 |
Disappearance of morphine-induced hyperalgesia after discontinuing or substituting morphine with other opioid agonists.
Topics: Adult; Aged; Analgesics, Opioid; Child; Delayed-Action Preparations; Female; Humans; Hyperalgesia; M | 1994 |
[Intra-arterial injection of pethidine for treatment of pain in chemoembolization of the liver].
Topics: Adult; Aged; Chemotherapy, Cancer, Regional Perfusion; Embolization, Therapeutic; Epirubicin; Female | 1994 |
Acute-phase response and sickle crisis.
Topics: Acute-Phase Reaction; Anemia, Sickle Cell; Humans; Meperidine; Pain | 1993 |
Epidural analgesia and uterine rupture during labour.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Bupivacaine; Female; Hemoperitoneum; Humans; Mep | 1994 |
Meperidine and ketorolac in the treatment of painful sickle cell crisis.
Topics: Analgesics; Anemia, Sickle Cell; Humans; Ketorolac; Meperidine; Pain; Tolmetin | 1993 |
Prolonged parenteral meperidine analgesia during pregnancy for pain from an abdominal wall mesh graft.
Topics: Abdominal Muscles; Adult; Analgesia; Analgesia, Patient-Controlled; Female; Humans; Infusions, Paren | 1993 |
Criteria for use of patient-controlled analgesia in adults.
Topics: Adult; Analgesia, Patient-Controlled; Fentanyl; Humans; Meperidine; Pain | 1993 |
Low-dose sulprostone for pregnancy termination in cases of fetal abnormality.
Topics: Abortifacient Agents, Nonsteroidal; Abortion, Therapeutic; Analgesia, Epidural; Dinoprostone; Female | 1993 |
Sickle cell pain crisis.
Topics: Analgesia; Analgesia, Patient-Controlled; Analgesics, Opioid; Anemia, Sickle Cell; Humans; Meperidin | 1996 |
Sickle cell pain crisis.
Topics: Analgesics, Opioid; Anemia, Sickle Cell; Humans; Meperidine; Morphine; Pain | 1996 |
Sickle cell pain crisis.
Topics: Analgesics, Opioid; Anemia, Sickle Cell; Humans; Meperidine; Morphine; Pain | 1996 |
Sickle cell pain crisis.
Topics: Analgesics, Opioid; Anemia, Sickle Cell; Contraindications; Humans; Meperidine; Pain; Practice Guide | 1996 |
Chronic renal failure revisited.
Topics: Analgesics, Opioid; Contraindications; Humans; Kidney Failure, Chronic; Meperidine; Pain | 1996 |
Minimizing meperidine use.
Topics: Acute Disease; Aged; Analgesics, Opioid; Contraindications; Humans; Meperidine; Pain; Practice Patte | 1996 |
International opioid consumption.
Topics: Analgesics, Opioid; Denmark; Drug Utilization; Humans; Meperidine; Methadone; Morphine; Pain | 1997 |
Meperidine-induced generalized seizures with normal renal function.
Topics: Abdominal Pain; Adult; Analgesics, Opioid; Cholinesterase Inhibitors; Chronic Disease; Epilepsy, Ton | 1997 |
Preliminary clinical use of a patient-controlled intranasal analgesia (PCINA) device.
Topics: Acute Disease; Administration, Inhalation; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Contro | 1997 |
Sedation for procedures.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Conscious Sedation; Drug Therapy, Combinati | 1997 |
Management of sickle cell disease. Non-addictive analgesics can be as effective as morphine and pethidine.
Topics: Acetaminophen; Analgesics, Opioid; Anemia, Sickle Cell; Child; Child, Preschool; Codeine; Drug Combi | 1998 |
Fast track admission for children with sickle cell crises. Opiates other than pethidine are better.
Topics: Analgesics, Opioid; Anemia, Sickle Cell; Child; Child, Preschool; Decision Making; Humans; Meperidin | 1998 |
Management of sickle cell disease. Management would improve if doctors listened more to patients.
Topics: Analgesics, Opioid; Anemia, Sickle Cell; Communication; Humans; Infusions, Intravenous; Meperidine; | 1998 |
Drugs for pain.
Topics: Acetaminophen; Administration, Oral; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Analgesics | 1998 |
Acute diverticulitis.
Topics: Acute Disease; Analgesics, Opioid; Diverticulitis, Colonic; Humans; Meperidine; Morphine; Pain | 1998 |
[Advantages and disadvantages of analgesia during childbirth].
Topics: Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Epidural; Female; Humans; Meperidine; Obstet | 1998 |
Multifaceted approach to medication use policy development: the restriction of meperidine.
Topics: Adverse Drug Reaction Reporting Systems; Analgesics, Opioid; Drug Utilization Review; Hospitals, Uni | 1997 |
Epidural analgesia for labor pain is not associated with a decreased frequency of uterine activity.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Local; Bupivaca | 1999 |
Meperidine utilization and compliance with Agency for Health Care Policy and Research guidelines in a tertiary care hospital.
Topics: Academic Medical Centers; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opi | 1999 |
Trends in medical use and abuse of opioid analgesics.
Topics: Analgesics, Opioid; Drug Utilization; Fentanyl; Humans; Hydromorphone; Meperidine; Morphine; Opioid- | 2000 |
[Meperidine (pethidine) outdated as analgesic in acute pancreatitis].
Topics: Acute Disease; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Contraindications; Drug Therapy, | 2000 |
[Morphine, pethidine or ketobemidone in acute pain--are there significant differences?].
Topics: Acute Disease; Analgesics, Opioid; Drug Interactions; Humans; Meperidine; Morphine; Pain | 2000 |
Parenteral narcotic analgesic for labour pain.
Topics: Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesics, Opioid; Clinical Trials as Topic; | 2000 |
Parenteral narcotic analgesic for labour pain 2.
Topics: Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesics, Opioid; Clinical Trials as Topic; | 2000 |
A quality improvement approach to reducing use of meperidine.
Topics: Analgesics, Opioid; Drug Utilization Review; Formularies, Hospital as Topic; Hospitals, University; | 2000 |
Meperidine--a liability.
Topics: Adult; Analgesics, Opioid; Central Nervous System Diseases; Contraindications; Humans; Liability, Le | 2001 |
Hydromorphone.
Topics: Analgesics, Opioid; Chronic Disease; Humans; Hydromorphone; Meperidine; Morphine; Neoplasms; Pain | 2001 |
Sympathetic dystrophy.
Topics: Analgesics, Opioid; Emergency Service, Hospital; Humans; Meperidine; Pain; Physician-Patient Relatio | 2001 |
Circadian distribution of oral opioid consumption in cancer patients.
Topics: Adult; Aged; Analgesics, Opioid; Circadian Rhythm; Drug Administration Schedule; Female; Humans; Mal | 2000 |
Substantial surveillance bias in an unblinded study of pain and adverse effects associated with nitrous oxide inhalation or standard medication for colonoscopy.
Topics: Administration, Inhalation; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Intravenous; | 2001 |
Transient neurological symptoms after subarachnoid meperidine.
Topics: Aged; Analgesics, Opioid; Anesthesia, Spinal; Humans; Male; Meperidine; Pain; Subarachnoid Space | 2002 |
Opioid use in chronic pain management in the Philippines.
Topics: Analgesics, Opioid; Chronic Disease; Fentanyl; Health Knowledge, Attitudes, Practice; Humans; Meperi | 2001 |
Safety concerns with meperidine.
Topics: Analgesics, Opioid; Humans; Meperidine; Pain | 2002 |
Patient pain during colonoscopy: an analysis using real-time magnetic endoscope imaging.
Topics: Analgesics; Butylscopolammonium Bromide; Colon; Colon, Sigmoid; Colonoscopy; Drug Combinations; Fema | 2002 |
Undertreatment of acute pain with narcotics.
Topics: Administration, Oral; Analgesics, Opioid; Codeine; Dose-Response Relationship, Drug; Drug Hypersensi | 1976 |
Pharmacotherapy II: narcotic and narcotic-antagonists analgesics.
Topics: Amines; Analgesics; Analgesics, Opioid; Binding Sites; Brain; Brain Chemistry; Codeine; Drug Toleran | 1978 |
Partial splenic embolization in the treatment of hypersplenism.
Topics: Adolescent; Adult; Anesthesia, Epidural; Embolization, Therapeutic; Evaluation Studies as Topic; Fem | 1979 |
Management of mild and severe alcoholic pancreatitis.
Topics: Alcoholism; Anesthesia, Epidural; Anti-Bacterial Agents; Glucagon; Humans; Intubation, Gastrointesti | 1975 |
Psychological, physiological, and pharmacological management of pain.
Topics: Age Factors; Analgesics; Anesthesia, Dental; Anxiety; Brain; Codeine; Dextropropoxyphene; Ethnicity; | 1977 |
Drug abuse and dependency in patients with chronic pain.
Topics: Age Factors; Chronic Disease; Codeine; Dextropropoxyphene; Diazepam; Female; Humans; Intelligence; M | 1979 |
Objective tests of analgesic drugs in ponies.
Topics: Analgesics; Animals; Disease Models, Animal; Female; Fentanyl; Horse Diseases; Horses; Male; Meperid | 1979 |
[Effect of scopolamine on pain and analgesic activity (author's transl)].
Topics: Analgesics; Animals; Differential Threshold; Drug Synergism; Meperidine; Mice; Norepinephrine; Pain; | 1979 |
The formalin test: a quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats.
Topics: Animals; Behavior, Animal; Brain Stem; Cats; Drug Evaluation; Forelimb; Formaldehyde; Injections, Su | 1977 |
Development of tolerance to morphine and pethidine in rats in dependence on age.
Topics: Age Factors; Animals; Drug Tolerance; Electroshock; Meperidine; Morphine; Pain; Rats | 1978 |
The use of microsurgical denervation of the spermatic cord for orchialgia.
Topics: Abdomen; Adult; Denervation; Hernia, Inguinal; Humans; Lidocaine; Male; Meperidine; Microsurgery; Pa | 1978 |
Acute cholecystitis.
Topics: Acute Disease; Anti-Bacterial Agents; Cholangiography; Cholecystectomy; Cholecystitis; Cholecystogra | 1975 |
Sedation and analgesia for minor painful procedures.
Topics: Analgesics; Anesthetics, Local; Barbiturates; Child; Chlorpromazine; Drug Therapy, Combination; Huma | 1977 |
Pharmacological modulations on the nociceptive flexion reflex in man.
Topics: Adult; Aspirin; Electric Stimulation; Female; Humans; Leg; Lidocaine; Male; Meperidine; Muscles; Nap | 1977 |
An obstetrician's view of pain.
Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Bupivacaine; Female; Fetus; Humans; Infant, Newborn; | 1976 |
An obstetrician's view of pain.
Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Female; Humans; Labor, Obstetric; Meperidine; Pain; | 1976 |
Analgesic requirements after orthognathic surgery.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Aspirin; Female; Humans; Male; Malocclusion; Meperidin | 1976 |
[Therapy of acute pancreatitis].
Topics: Acute Disease; Anti-Bacterial Agents; Aprotinin; Fasting; Glucagon; Humans; Meperidine; Pain; Pancre | 1976 |
[Shock and pain treatment by ambulance personnel].
Topics: Emergencies; First Aid; Humans; Injections, Intravenous; Legislation, Nursing; Meperidine; Netherlan | 1975 |
The effect of meperidine analgesia on midtrimester abortions induced with intra-amniotic prostaglandin F2alpha.
Topics: Abortion, Induced; Adolescent; Adult; Endometritis; Female; Humans; Meperidine; Pain; Pregnancy; Pre | 1976 |
Alterations in response to somatic pain associated with anaesthesia. XXIII: Further study of naloxone.
Topics: Anesthesia, Intravenous; Humans; Meperidine; Naloxone; Pain | 1976 |
How i treat acute pancreatitis.
Topics: Acetazolamide; Acute Disease; Humans; Meperidine; Pain; Pancreatitis; Parasympatholytics | 1976 |
Sickle cell vaso-occlusive pain crisis in adults: alternative strategies for management in the emergency department.
Topics: Acetaminophen; Adolescent; Adult; Amitriptyline; Analgesics; Anemia, Sickle Cell; Anti-Inflammatory | 1992 |
Survey of pain management therapy provided for children with sickle cell disease.
Topics: Acetaminophen; Analgesics; Anemia, Sickle Cell; Child; Child, Preschool; Codeine; Drug Administratio | 1992 |
Reaction time in cancer patients receiving peripherally acting analgesics alone or in combination with opioids.
Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Female; Hum | 1992 |
Pethidine in sickle cell crisis.
Topics: Anemia, Sickle Cell; Humans; Meperidine; Pain | 1992 |
Midazolam-fentanyl sedation in conjunction with local anesthesia during oocyte retrieval for in vitro fertilization.
Topics: Drug Therapy, Combination; Female; Fentanyl; Fertilization in Vitro; Humans; Injections, Intramuscul | 1992 |
Effects of perineural opioids on nerve conduction of N. suralis in man.
Topics: Adult; Anesthesia, Epidural; Anesthesiology; Endorphins; Female; Fentanyl; Humans; Injections, Epidu | 1992 |
Undertreatment of cancer pain.
Topics: Humans; Meperidine; Morphine; Neoplasms; Pain | 1991 |
Pethidine for painful crises in sickle cell disease.
Topics: Adult; Hemoglobin SC Disease; Humans; Male; Meperidine; Pain | 1991 |
The King Edward Memorial Hospital 1,000 mother survey of methods of pain relief in labour.
Topics: Administration, Inhalation; Analgesia, Epidural; Analgesia, Obstetrical; Attitude; Bupivacaine; Fema | 1991 |
Premedication and short term complications in iohexol discography.
Topics: Adult; Back Pain; Diazepam; Female; Glycopyrrolate; Headache; Humans; Injections, Spinal; Interverte | 1991 |
[Premedication and analgesic dose procedures in dental medicine].
Topics: Anesthesia, Dental; Anesthesia, Local; Buprenorphine; Clorazepate Dipotassium; Diazepam; Flunitrazep | 1991 |
IM MPC in children: safe and effective or a poor choice?
Topics: Child; Chlorpromazine; Drug Therapy, Combination; Emergencies; Humans; Injections, Intramuscular; Me | 1991 |
Antinociceptive interaction between opioids and medetomidine: systemic additivity and spinal synergy.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Drug Interactions; Drug Synergism; Fentanyl; | 1990 |
[Pain therapy for urologic cancer patients at the Potsdam district hospital--initial results].
Topics: Aged; Amitriptyline; Analgesics; Analgesics, Opioid; Aspirin; Carbamazepine; Codeine; Dipyrone; Drug | 1990 |
Prolongation of the pharmacologic effect of intrathecal meperidine by the use of a lipid solution of it.
Topics: Animals; Injections, Spinal; Male; Meperidine; Motor Activity; Pain; Rabbits; Solutions | 1991 |
When and why I use pethidine.
Topics: Humans; Meperidine; Pain; Substance-Related Disorders | 1991 |
[Effects of the pineal body and melatonin on sensitivity to pain in mice].
Topics: Animals; Circadian Rhythm; Female; Melatonin; Meperidine; Mice; Morphine; Pain; Pineal Gland; Sensor | 1990 |
The use of obstetric analgesia in Sweden 1983-1986.
Topics: Adolescent; Adult; Analgesia, Epidural; Analgesia, Obstetrical; Female; Humans; Interpersonal Relati | 1990 |
Patients know their own pain best.
Topics: Adaptation, Psychological; Female; Humans; Meperidine; Pain; Self Care; Substance-Related Disorders | 1990 |
Diagnostic epidural opioid blockade in primary fibromyalgia at rest and during exercise.
Topics: Adult; Female; Fibromyalgia; Humans; Injections, Spinal; Meperidine; Middle Aged; Pain; Physical Exe | 1989 |
Racemic and optically active trans 2,6-dimethyl analogues of the reversed ester of pethidine.
Topics: Analgesics; Animals; Meperidine; Mice; Pain; Promedol; Rats; Stereoisomerism; Structure-Activity Rel | 1986 |
Management of pain caused by pancreatitis.
Topics: Acute Disease; Child; Humans; Meperidine; Narcotic Antagonists; Pain; Pancreatitis | 1989 |
[Interaction of analgesics and l-stepholidine].
Topics: Analgesics; Animals; Berberine; Berberine Alkaloids; Dogs; Drug Synergism; Electroencephalography; E | 1986 |
The use of opioids in the management of pain.
Topics: Humans; Meperidine; Morphine; Narcotics; Nausea; Pain; Receptors, Opioid; Vomiting | 1986 |
The use of clonidine for the treatment of meperidine withdrawal in a multidisciplinary pain program setting. A case presentation.
Topics: Adult; Clonidine; Combined Modality Therapy; Drug Administration Schedule; Female; Humans; Meperidin | 1987 |
An alcoholic woman with acute abdominal pain.
Topics: Abdomen; Adult; Alcoholism; Female; Fluid Therapy; Humans; Meperidine; Pain; Pancreatitis; Suction | 1987 |
Estimation of single-evoked cerebral potentials by means of parametric modeling and Kalman filtering.
Topics: Brain; Computer Simulation; Electric Stimulation; Electroencephalography; Evoked Potentials, Somatos | 1988 |
The effect of buprenorphine on the analgesic and respiratory depressant effects of pethidine: a preliminary study.
Topics: Adult; Buprenorphine; Drug Interactions; Humans; Male; Meperidine; Middle Aged; Pain; Reaction Time; | 1988 |
Epidural xylocaine and pethidine for control of labor pain--a comparative study.
Topics: Adult; Analgesia, Epidural; Anesthesia, Obstetrical; Female; Humans; Labor, Obstetric; Lidocaine; Me | 1988 |
Maternal arterial oxygen saturation during labor and delivery: pain-dependent alterations and effects on the newborn.
Topics: Acid-Base Equilibrium; Anesthesia, Epidural; Anesthesia, Obstetrical; Delivery, Obstetric; Female; H | 1987 |
Meperidine-induced hypereosinophilia: report of a case.
Topics: Adult; Arm Injuries; Eosinophilia; Humans; Male; Meperidine; Pain | 1987 |
[Effects of lidocaine, meperidine or fentanyl on pain and clinical thrombophlebitis induced by intravenous diazepam].
Topics: Adult; Diazepam; Female; Fentanyl; Humans; Hydrogen-Ion Concentration; Injections, Intravenous; Lido | 1987 |
The influence of drug polarity on the absorption of opioid drugs into CSF and subsequent cephalad migration following lumbar epidural administration: application to morphine and pethidine.
Topics: Blood-Brain Barrier; Chemical Phenomena; Chemistry; Drug Therapy, Combination; Humans; Injections, E | 1987 |
Epidural administration of opiates by a new device.
Topics: Anesthesia, Epidural; Buprenorphine; Catheters, Indwelling; Humans; Infusion Pumps; Meperidine; Morp | 1987 |
Treatment for cancer pain.
Topics: Heroin; Humans; Meperidine; Neoplasms; Pain | 1986 |
Intravenous narcotic therapy for children with severe sickle cell pain crisis.
Topics: Adolescent; Anemia, Sickle Cell; Child; Female; Humans; Infusions, Intravenous; Male; Meperidine; Mo | 1986 |
Meperidine usage in patients with sickle cell crisis.
Topics: Anemia, Sickle Cell; Humans; Meperidine; Pain | 1986 |
Stimulation of the periaqueductal gray subdues sensitized pain in morphine- and meperidine-dependent rats.
Topics: Animals; Humans; Male; Meperidine; Morphine; Naloxone; Nociceptors; Pain; Periaqueductal Gray; Rats; | 1985 |
Serum concentrations of meperidine in patients with sickle cell crisis.
Topics: Absorption; Adult; Anemia, Sickle Cell; Body Weight; Chromatography, Gas; Female; Humans; Injections | 1986 |
Visceral analgesia: effects of xylazine, butorphanol, meperidine, and pentazocine in horses.
Topics: Analgesia; Animals; Behavior, Animal; Butorphanol; Colic; Female; Heart; Horse Diseases; Horses; Mal | 1985 |
Parenteral meptazinol--international clinical experience.
Topics: Azepines; Dose-Response Relationship, Drug; Female; Humans; Meperidine; Meptazinol; Obstetric Labor | 1985 |
Pain in haemophilia.
Topics: Acetaminophen; Analgesics; Hemophilia A; Humans; Indomethacin; Male; Meperidine; Oxyphenbutazone; Pa | 1973 |
[Analgesia in myocardial infarct].
Topics: Analgesics; Diazepam; Heart; Hemodynamics; Heroin; Humans; Hydromorphone; Meperidine; Methadone; Mor | 1974 |
Relief of pain in labour.
Topics: Adult; Barbiturates; Female; Humans; Labor, Obstetric; Meperidine; Morphine; Opium; Pain; Pregnancy; | 1967 |
Dental evaluation of hydromorphone (Dilaudid) for oral and maxillo-facial surgery.
Topics: Hydromorphone; Meperidine; Pain; Postoperative Care; Surgery, Oral | 1969 |
Anesthesia for diagnostic and operative laparoscopy.
Topics: Abdomen; Adolescent; Adult; Analgesia; Anesthesia; Anesthesia, General; Anesthesia, Local; Diazepam; | 1971 |
Analgesics in the acute phase of myocardial infarction.
Topics: Acute Disease; Analgesics; Cardiac Output; Humans; Injections, Intramuscular; Injections, Intravenou | 1974 |
Relationship between analgesic action of pethidine and its effect on the brain 5-hydroxytryptamine concentration in the rats of different age.
Topics: Age Factors; Animals; Brain Chemistry; Female; Male; Meperidine; Pain; Rats; Rats, Inbred Strains; S | 1974 |
Relief of pain in labor.
Topics: Analgesics; Anesthesia, Conduction; Anesthesia, Inhalation; Anesthesia, Obstetrical; Cervix Uteri; F | 1974 |
Analgesia and anaesthesia in labour.
Topics: Analgesia; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Obstetrical; Cesarean Section; Fem | 1974 |
Letter: Meperidine vs morphine.
Topics: Chronic Disease; Humans; Meperidine; Morphine; Pain | 1974 |
Use of sedation-analgesia in general dentistry.
Topics: Analgesia; Anesthesia, Dental; Diazepam; Humans; Meperidine; Nitrous Oxide; Pain; Pentobarbital; Sco | 1973 |
Intra-amniotic administration of prostaglandin F 2 for induction of therapeutic abortion. A comparison of four dosage schedules.
Topics: Abortion, Therapeutic; Adolescent; Adult; Amniotic Fluid; Dose-Response Relationship, Drug; Female; | 1972 |
[Comparative study of analgesic drugs in postoperative pain].
Topics: Aminopyrine; Analgesics; Fentanyl; Humans; Meperidine; Pain; Pentazocine; Postoperative Complication | 1972 |
The use of pentazocine as a strong analgesic in urological practice.
Topics: Adult; Analgesics; Body Weight; Female; Humans; Injections, Intramuscular; Male; Meperidine; Middle | 1973 |
[Comparative evaluation of analgesic action of dolargan and nozinan in patients following epigastric operations].
Topics: Adult; Analgesics; Female; Gastrointestinal Diseases; Humans; Male; Meperidine; Methotrimeprazine; M | 1973 |
Sufficient treatment for pain.
Topics: Humans; Meperidine; Narcotics; Pain | 1973 |
Alterations in response to somatic pain associated with anaesthesia. XXII. Nikethamide, doxapram and naloxone.
Topics: Anesthesia; Body Weight; Doxapram; Female; Humans; Meperidine; Morphine; Naloxone; Nikethamide; Pain | 1973 |
Measurement of analgesia using a spatial preference test in the rat.
Topics: Analgesia; Animals; Avoidance Learning; Codeine; Cyclazocine; Differential Threshold; Dose-Response | 1973 |
[Analgesia and anaesthesia during labour and delivery. (Symposion by letter) (author's transl)].
Topics: Acidosis, Respiratory; Analgesia; Anesthesia, Conduction; Anesthesia, Epidural; Anesthesia, Obstetri | 1973 |
Patient's views on general anaesthesia.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthesia, Inhalation; Attitude; Cognition; Diazepam; | 1973 |
Analgesics.
Topics: Analgesics; Aspirin; Codeine; Humans; Meperidine; Morphine; Pain; Pentazocine; Tranquilizing Agents | 1973 |
Reversal by narcotics and narcotic antagonists of pain-induced functional impairment.
Topics: Analgesics; Animals; Codeine; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; | 1973 |
Anti-nociceptive activity of some thiophthalanes with morphine-like properties.
Topics: Analgesia; Analgesics; Animals; Bridged-Ring Compounds; Depression, Chemical; Dextropropoxyphene; Di | 1973 |
[Treatment of patients with pains].
Topics: Humans; Medication Errors; Meperidine; Pain | 1974 |
Dosage and choice of parenteral strong analgesics.
Topics: Analgesics; Codeine; Drug Prescriptions; Humans; Infusions, Parenteral; Meperidine; Morphinans; Morp | 1974 |
[On the medical treatment of acute pancreatitis].
Topics: Acute Disease; Diet Therapy; Ergoloid Mesylates; Humans; Meperidine; Pain; Pancreatitis; Promethazin | 1967 |
[Guidelines for medical assistance in a mass disaster of burns].
Topics: Accidents; Adolescent; Adult; Albumins; Blood Transfusion; Burns; Carbohydrates; Child; Child, Presc | 1971 |
Postoperative analgesia--comparison of methotrimeprazine (Nozinan) and meperidine (Demerol) as postoperative analgesia agents.
Topics: Adolescent; Adult; Aged; Analgesia; Blood Pressure; Female; Humans; Male; Meperidine; Methotrimepraz | 1972 |
Methadone maintenance therapy for heroin addiction. Some surgical considerations.
Topics: Adult; Cardiac Surgical Procedures; Curettage; Dextropropoxyphene; Dilatation; Female; Fracture Fixa | 1972 |
Postoperative demand analgesia.
Topics: Analgesia; Analgesics; Humans; Injections, Intravenous; Meperidine; Pain; Postoperative Care; Self M | 1972 |
[Clinical experience with perlingnal alleviation of pain following tonsillectomy and intubetion anesthesia].
Topics: Humans; Intubation, Intratracheal; Meperidine; Pain; Postoperative Care; Tonsillectomy | 1972 |
[Effect of sedatives on pain threshold].
Topics: Adult; Diazepam; Female; Humans; Hypnotics and Sedatives; Meperidine; Pain; Pentazocine; Pentobarbit | 1971 |
Comparative responses of pentazocine & meperidine for control of postoperative pain in dogs. (A blind study).
Topics: Animals; Dog Diseases; Dogs; Evaluation Studies as Topic; Meperidine; Pain; Pentazocine; Postoperati | 1971 |
Effect of pain relief on arterial blood gas values during labor.
Topics: Arteries; Carbon Dioxide; Female; Humans; Labor, Obstetric; Meperidine; Oxygen; Pain; Pregnancy; Res | 1969 |
A method of intravenous medication.
Topics: Anxiety; Humans; Injections, Intravenous; Meperidine; Pain; Pentobarbital; Preanesthetic Medication; | 1969 |
Methotrimeprazine: evaluated as an analgesic following oral surgery.
Topics: Analgesics; Humans; Meperidine; Methotrimeprazine; Pain; Postoperative Complications; Surgery, Oral | 1967 |
Ligation treatment of haemorrhoids in the surgery: an appraisal.
Topics: Adult; Aged; Ambulatory Care; Anus Diseases; Codeine; Female; Gastrointestinal Hemorrhage; Hemorrhoi | 1969 |
Treatment of soft tissue injuries at the roadside.
Topics: Accidents, Traffic; Acute Kidney Injury; Bandages; Facial Injuries; First Aid; Hemorrhage; Humans; J | 1969 |
4-Dimethyl-amino methyl-2-methyl 1,3 dioxolane--a new potent analgesic agent.
Topics: Analgesics; Animals; Aspirin; Caffeine; Codeine; Dextropropoxyphene; Dioxoles; Electric Stimulation; | 1969 |
Narcotic analgesics--I.
Topics: Acute Disease; Analgesics; Anesthesia, Obstetrical; Chronic Disease; Female; Humans; Infant, Newborn | 1970 |
Control of rectal postoperative pain by use of long-lasting steroids.
Topics: Analgesics; Humans; Meperidine; Methylprednisolone; Pain; Postoperative Care; Rectal Diseases; Time | 1970 |
Obstetric analgesia. A consideration of labor pain and a patient-controlled technique for its relief with meperidine.
Topics: Anesthesia, Obstetrical; Female; Humans; Labor, Obstetric; Meperidine; Methods; Pain; Pregnancy | 1970 |
Pneumothorax following "trigger point" injection.
Topics: Adult; Anesthesia, Local; Humans; Iatrogenic Disease; Injections; Male; Meperidine; Neck; Pain; Pneu | 1970 |
[Use of tranquilizers in relief of postoperative pain].
Topics: Diazepam; Humans; Hydroxyzine; Meperidine; Pain; Postoperative Care; Tranquilizing Agents | 1970 |
[Association of meperidine and the succinic ether of oxazepam in postoperative analgesia-sedation].
Topics: Humans; Meperidine; Oxazepam; Pain; Postoperative Care; Succinates | 1970 |
Pancreatic problems. 1. Acute pancreatitis.
Topics: Acute Disease; Albumins; Alcoholism; Amylases; Ascitic Fluid; Blood Transfusion; Calcium; Cholelithi | 1971 |
[Postoperative pain control].
Topics: Abdomen; Adolescent; Adult; Aged; Anesthesia, Conduction; Anesthetics, Local; Female; Humans; Laparo | 1967 |
[Clinical study of the effects of various cocktail preparations containing hydrochloric pethidine as a principal constituent upon the palliation of pain during delivery].
Topics: Animals; Blood Pressure; Female; Fetus; Humans; Labor, Obstetric; Levallorphan; Meperidine; Pain; Pr | 1968 |
X. Effects of opioids on electrical activity of deep structures in the human brain.
Topics: Electrophysiology; Humans; Meperidine; Pain; Thalamus | 1968 |
Analgetic activity of cyclized basic anilides.
Topics: Analgesia; Analgesics; Anilides; Animals; Chemical Phenomena; Chemistry; Meperidine; Mice; Pain | 1969 |
Chlormethiazole in the prevention of eclampsia and the reduction of perinatal mortality.
Topics: Adolescent; Adult; Birth Weight; Chlormethiazole; Drug Synergism; Eclampsia; Female; Humans; Hypnoti | 1969 |