mepenzolate has been researched along with Pulmonary Disease, Chronic Obstructive in 3 studies
mepenzolic acid: anticholinergic, antispasmodic agent; RN given refers to parent cpd; structure
Pulmonary Disease, Chronic Obstructive: A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mepenzolate has an asymmetric carbon atom, thus providing us with the opportunity to synthesize both of its enantiomers ((R)- and (S)-mepenzolate) and to examine their biochemical and pharmacological activities." | 1.40 | Synthesis and biological comparison of enantiomers of mepenzolate bromide, a muscarinic receptor antagonist with bronchodilatory and anti-inflammatory activities. ( Asano, T; Fukunishi, Y; Hanaya, K; Ishihara, T; Kobayashi, D; Mashimo, T; Mizushima, T; Shoji, M; Sugai, T; Tanaka, K; Wada, M; Yamakawa, N; Yamashita, Y, 2014) |
| "The clinical treatment of chronic obstructive pulmonary disease (COPD) requires not only an improvement of airflow by bronchodilation but also the suppression of emphysema by controlling inflammation." | 1.39 | Mepenzolate bromide displays beneficial effects in a mouse model of chronic obstructive pulmonary disease. ( Iijima, K; Ishihara, T; Kobayashi, D; Mizushima, T; Mogushi, K; Sato, K; Sugizaki, T; Suzuki, H; Tahara, K; Tanaka, H; Tanaka, K; Yamakawa, N; Yamashita, Y, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tanaka, K | 3 |
| Ishihara, T | 3 |
| Sugizaki, T | 1 |
| Kobayashi, D | 3 |
| Yamashita, Y | 3 |
| Tahara, K | 1 |
| Yamakawa, N | 3 |
| Iijima, K | 1 |
| Mogushi, K | 1 |
| Tanaka, H | 1 |
| Sato, K | 1 |
| Suzuki, H | 2 |
| Mizushima, T | 3 |
| Kurotsu, S | 1 |
| Asano, T | 2 |
| Yamazaki, H | 1 |
| Watanabe, H | 1 |
| Maruyama, T | 1 |
| Hanaya, K | 1 |
| Shoji, M | 1 |
| Sugai, T | 1 |
| Wada, M | 1 |
| Mashimo, T | 1 |
| Fukunishi, Y | 1 |
3 other studies available for mepenzolate and Pulmonary Disease, Chronic Obstructive
| Article | Year |
|---|---|
Mepenzolate bromide displays beneficial effects in a mouse model of chronic obstructive pulmonary disease.
Topics: Administration, Inhalation; Animals; Anions; Anti-Inflammatory Agents; Benzilates; Bronchoalveolar L | 2013 |
Superiority of pulmonary administration of mepenzolate bromide over other routes as treatment for chronic obstructive pulmonary disease.
Topics: Airway Resistance; Animals; Anti-Inflammatory Agents; Benzilates; Disease Models, Animal; Drug Admin | 2014 |
Synthesis and biological comparison of enantiomers of mepenzolate bromide, a muscarinic receptor antagonist with bronchodilatory and anti-inflammatory activities.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzilates; Bronchodilator Agents; Dose-Response R | 2014 |