Page last updated: 2024-10-21

menthol and Muscle Contraction

menthol has been researched along with Muscle Contraction in 21 studies

Menthol: A monoterpene cyclohexanol produced from mint oils.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"To investigate the effects of menthol, an activator of the temperature-sensitive transient receptor potential family member TRPM8, on detrusor smooth-muscle contraction and the micturition reflex in rats."7.74Effect of menthol on detrusor smooth-muscle contraction and the micturition reflex in rats. ( Harada, K; Ikeda, S; Kamikawa, Y; Kawahira, K; Nomoto, Y; Ohwatashi, A; Yoshida, A, 2008)
"To investigate the effects of menthol, an activator of the temperature-sensitive transient receptor potential family member TRPM8, on detrusor smooth-muscle contraction and the micturition reflex in rats."3.74Effect of menthol on detrusor smooth-muscle contraction and the micturition reflex in rats. ( Harada, K; Ikeda, S; Kamikawa, Y; Kawahira, K; Nomoto, Y; Ohwatashi, A; Yoshida, A, 2008)
"Hypersensitivity was also observed with or without prior bladder distention, although the magnitude of electromyogram responses during ice water testing significantly correlated with the magnitude of electromyogram responses to bladder distention."1.35Ice water testing reveals hypersensitivity in adult rats that experienced neonatal bladder inflammation: implications for painful bladder syndrome/interstitial cystitis. ( Mebane, H; Ness, TJ; Randich, A, 2009)
"Muscle contractions were evoked every 10 minutes, alternating between hind limbs, for 120 minutes."1.32Effects of a menthol-based analgesic balm on pressor responses evoked from muscle afferents in cats. ( Bell, GW; Foreman, JH; Iwamoto, GA; Nelson, AJ; Ragan, BG, 2004)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.76)18.7374
1990's1 (4.76)18.2507
2000's7 (33.33)29.6817
2010's10 (47.62)24.3611
2020's2 (9.52)2.80

Authors

AuthorsStudies
Chou, YL1
Wang, YT1
Cheng, LH1
Liu, SC2
Wang, HW2
Liu, J1
Liu, L1
Zhao, M1
Ding, N1
Ge, N1
Daugherty, SL1
Beckel, JM1
Wang, S1
Zhang, X1
de Oliveira, MG1
Nascimento, DM1
Alexandre, EC1
Bonilla-Becerra, SM1
Zapparoli, A1
Mónica, FZ1
Antunes, E2
Vahabi, B1
Parsons, BA1
Doran, O1
Rhodes, A1
Dean, S1
Drake, MJ1
Amato, A2
Baldassano, S1
Serio, R1
Mulè, F2
Liotta, R1
Ramos-Filho, AC1
Shah, A1
Augusto, TM1
Barbosa, GO1
Leiria, LO1
de Carvalho, HF1
Grant, AD1
Zhang, L1
An, X1
Wang, Q1
He, M1
Melanaphy, D1
Johnson, CD1
Kustov, MV1
Watson, CA1
Borysova, L1
Burdyga, TV1
Zholos, AV1
Chao, PZ1
Lee, FP1
Ito, S1
Kume, H1
Shiraki, A1
Kondo, M1
Makino, Y1
Kamiya, K1
Hasegawa, Y1
Randich, A1
Mebane, H1
Ness, TJ1
Filippov, IB3
Vladymyrova, IA3
Kuliieva, IeM2
Skryma, R2
Prevarskaia, N2
Shuba, IaM3
Iurkevych, A1
Paduraru, OM1
Boldyriev, OI1
Naĭd'onov, VH1
Ragan, BG1
Nelson, AJ1
Foreman, JH1
Bell, GW1
Iwamoto, GA1
Tsukimi, Y1
Mizuyachi, K1
Yamasaki, T1
Niki, T1
Hayashi, F1
Hong, Z1
Hong, F1
Olschewski, A1
Cabrera, JA1
Varghese, A1
Nelson, DP1
Weir, EK1
Nomoto, Y1
Yoshida, A1
Ikeda, S1
Kamikawa, Y1
Harada, K1
Ohwatashi, A1
Kawahira, K1
Beuscher, N1
Kietzmann, M1
Bien, E1
Champeroux, P1
White, JR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Liberal Versus Restrictive Platelet Transfusion for Treatment of Hemodynamically Significant Patent Ductus Arteriosus in Thrombocytopenic Preterm Neonates- A Randomized Open Label, Controlled Trial[NCT03022253]Phase 344 participants (Anticipated)Interventional2016-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for menthol and Muscle Contraction

ArticleYear
Effects of a counterirritant on perceived pain and hand movement in patients with arthritis.
    Physical therapy, 1973, Volume: 53, Issue:9

    Topics: Adult; Aged; Arthritis, Rheumatoid; Audiometry; Female; Finger Joint; Hand; Humans; Irritants; Male;

1973

Other Studies

20 other studies available for menthol and Muscle Contraction

ArticleYear
Efficacy of levocetirizine in isolated rat tracheal smooth muscle.
    International journal of medical sciences, 2023, Volume: 20, Issue:13

    Topics: Animals; Cetirizine; Humans; Menthol; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Rat

2023
Activation of TRPM8 channel inhibits contraction of the isolated human ureter.
    Neurourology and urodynamics, 2021, Volume: 40, Issue:6

    Topics: Calcitonin Gene-Related Peptide; Humans; Membrane Proteins; Menthol; Muscle Contraction; Transient R

2021
Menthol ameliorates voiding dysfunction in types I and II diabetic mouse model.
    Neurourology and urodynamics, 2018, Volume: 37, Issue:8

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diet

2018
TRPM8 agonists modulate contraction of the pig urinary bladder.
    Canadian journal of physiology and pharmacology, 2013, Volume: 91, Issue:7

    Topics: Animals; Female; Menthol; Muscle Contraction; Pyrimidinones; Swine; TRPM Cation Channels; Urinary Bl

2013
Tetrodotoxin-dependent effects of menthol on mouse gastric motor function.
    European journal of pharmacology, 2013, Oct-15, Volume: 718, Issue:1-3

    Topics: Acetylcholine; Animals; Biomechanical Phenomena; Gastric Emptying; Gastric Mucosa; In Vitro Techniqu

2013
Effects of menthol on circular smooth muscle of human colon: analysis of the mechanism of action.
    European journal of pharmacology, 2014, Oct-05, Volume: 740

    Topics: Aged; Aged, 80 and over; Calcium Channel Blockers; Calcium Channels, L-Type; Carbachol; Colon; Elect

2014
Menthol inhibits detrusor contractility independently of TRPM8 activation.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Animals; Calcium Channel Blockers; Calcium Chloride; Carbachol; Cells, Cultured; Electric Stimulatio

2014
Activation of Cold-Sensitive Channels TRPM8 and TRPA1 Inhibits the Proliferative Airway Smooth Muscle Cell Phenotype.
    Lung, 2016, Volume: 194, Issue:4

    Topics: Actins; Airway Remodeling; Animals; Asthma; Bronchi; Calcium Channel Agonists; Cell Movement; Cell P

2016
Ion channel mechanisms of rat tail artery contraction-relaxation by menthol involving, respectively, TRPM8 activation and L-type Ca2+ channel inhibition.
    American journal of physiology. Heart and circulatory physiology, 2016, 12-01, Volume: 311, Issue:6

    Topics: Anilides; Animals; Antipruritics; Arteries; Calcium Channels, L-Type; Calcium Signaling; Immunohisto

2016
Menthol inhibiting parasympathetic function of tracheal smooth muscle.
    International journal of medical sciences, 2016, Volume: 13, Issue:12

    Topics: Animals; Electric Stimulation; In Vitro Techniques; Menthol; Methacholine Chloride; Muscle Contracti

2016
Inhibition by the cold receptor agonists menthol and icilin of airway smooth muscle contraction.
    Pulmonary pharmacology & therapeutics, 2008, Volume: 21, Issue:5

    Topics: Animals; Calcium; Cold Temperature; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniqu

2008
Ice water testing reveals hypersensitivity in adult rats that experienced neonatal bladder inflammation: implications for painful bladder syndrome/interstitial cystitis.
    The Journal of urology, 2009, Volume: 182, Issue:1

    Topics: Administration, Intravesical; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Cystitis

2009
[Modulation of the smooth muscle contractions of the rat vas deferens by TRPM8 channel agonist menthol].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2009, Volume: 55, Issue:6

    Topics: Animals; Calcium; Calcium-Transporting ATPases; Capsaicin; Carbachol; Cold Temperature; In Vitro Tec

2009
[Comparative effects of menthol and icilin on the induced contraction of the smooth muscles of the vas deferens of normal and castrated rats].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2011, Volume: 57, Issue:4

    Topics: Adrenergic alpha-Agonists; Animals; Epididymis; Male; Menthol; Muscarinic Agonists; Muscle Contracti

2011
[Urothelium-dependent modulation of urinary bladder smooth muscle contractions by menthol].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2011, Volume: 57, Issue:6

    Topics: Animals; In Vitro Techniques; Male; Menthol; Muscle Contraction; Muscle, Smooth; Myocytes, Smooth Mu

2011
Effects of a menthol-based analgesic balm on pressor responses evoked from muscle afferents in cats.
    American journal of veterinary research, 2004, Volume: 65, Issue:9

    Topics: Administration, Topical; Analgesics; Analysis of Variance; Animals; Blood Pressure; Cats; Electric S

2004
Cold response of the bladder in guinea pig: involvement of transient receptor potential channel, TRPM8.
    Urology, 2005, Volume: 65, Issue:2

    Topics: Afferent Pathways; Animals; Capsaicin; Cold Temperature; Female; Ganglia, Spinal; Guinea Pigs; Hexam

2005
Role of store-operated calcium channels and calcium sensitization in normoxic contraction of the ductus arteriosus.
    Circulation, 2006, Sep-26, Volume: 114, Issue:13

    Topics: Animals; Arachidonic Acids; Boron Compounds; Calcium; Calcium Channel Blockers; Calcium Channels, L-

2006
Effect of menthol on detrusor smooth-muscle contraction and the micturition reflex in rats.
    Urology, 2008, Volume: 72, Issue:3

    Topics: Animals; Antipruritics; Capsaicin; Carbachol; Female; Menthol; Muscle Contraction; Muscle, Smooth; R

2008
Interference of myrtol standardized with inflammatory and allergic mediators.
    Arzneimittel-Forschung, 1998, Volume: 48, Issue:10

    Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Basophils; Cattle; Cyclohexanols; Dinoprosto

1998