Page last updated: 2024-10-21

menthol and Inflammation

menthol has been researched along with Inflammation in 20 studies

Menthol: A monoterpene cyclohexanol produced from mint oils.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"The decrease in pro-inflammatory cytokines and related inflammatory markers, as well as associated pathway activation, was found to play the greatest role in the protective effects of menthol against inflammatory damage or association with protection against chronic inflammation."9.22Cold stimuli, hot topic: An updated review on the biological activity of menthol in relation to inflammation. ( An, X; Cheng, H, 2022)
"To screen potent terpenoid compounds against allergic inflammation in vitro and in vivo, five terpenoid compounds including menthone, farnesol, oridonin, β-escin and lupeol, were first selected to compare their anti-allergic inflammation potential using mouse lung mast cells in vitro."8.12Menthone supplementation protects from allergic inflammation in the lungs of asthmatic mice. ( Lin, JY; Su, YH, 2022)
"In conclusion, our results suggest that dietary menthol can protect against inflammation and cardiac remodeling after MI through activation of TRPM8."7.96Dietary Menthol Attenuates Inflammation and Cardiac Remodeling After Myocardial Infarction via the Transient Receptor Potential Melastatin 8. ( Chen, K; Peng, K; Tang, B; Wang, Q; Wang, Z; Yang, D; Yang, P; Yang, Y, 2020)
"Chlorpyrifos (CPF) is one of the predominant water pollutants associated with inflammation and immunodepression in aquatic animals."7.96The impact of menthol essential oil against inflammation, immunosuppression, and histopathological alterations induced by chlorpyrifos in Nile tilapia. ( Abdel-Latif, HMR; Abdel-Razek, MAS; Abdel-Razik, NI; Abdo, SE; Amer, AA; Dawood, MAO; El-Salam Metwally, A; Elkomy, AH; Gewaily, MS; Paray, BA; Soliman, AA, 2020)
"To investigate the role of mammalian target of rapamycin (mTOR) activation in menthol-induced expression of airway inflammation- related factors in human bronchial epithelial cells and explore its mechanism."7.91[Role of mammalian target of rapamycin activation in menthol-induced expressions of airway inflammation-related factors in human bronchial epithelial cells ( Chen, H; Li, M, 2019)
"Chronic inflammation is a potential systemic risk factor for many bladder dysfunctions, including interstitial cystitis (IC)."5.48Menthol, a unique urinary volatile compound, is associated with chronic inflammation in interstitial cystitis. ( Cho, E; Kim, J; Lee, MY; Sairam, V; Shahid, M; Valdiviez, L; Yeon, A; You, S, 2018)
"Pretreatment with menthol at various doses significantly suppressed tumor formation and growth, and markedly reduced tumor incidence and volume."5.42Chemopreventive efficacy of menthol on carcinogen-induced cutaneous carcinoma through inhibition of inflammation and oxidative stress in mice. ( Cao, Y; Chen, C; Fan, F; Lin, C; Liu, Z; Lu, Y; Shan, Y; Shen, C; Sun, L; Tao, Y; Wang, A; Wang, S; Wei, Z; Wu, H; Zheng, S; Zhu, P, 2015)
"The decrease in pro-inflammatory cytokines and related inflammatory markers, as well as associated pathway activation, was found to play the greatest role in the protective effects of menthol against inflammatory damage or association with protection against chronic inflammation."5.22Cold stimuli, hot topic: An updated review on the biological activity of menthol in relation to inflammation. ( An, X; Cheng, H, 2022)
"To screen potent terpenoid compounds against allergic inflammation in vitro and in vivo, five terpenoid compounds including menthone, farnesol, oridonin, β-escin and lupeol, were first selected to compare their anti-allergic inflammation potential using mouse lung mast cells in vitro."4.12Menthone supplementation protects from allergic inflammation in the lungs of asthmatic mice. ( Lin, JY; Su, YH, 2022)
"In conclusion, our results suggest that dietary menthol can protect against inflammation and cardiac remodeling after MI through activation of TRPM8."3.96Dietary Menthol Attenuates Inflammation and Cardiac Remodeling After Myocardial Infarction via the Transient Receptor Potential Melastatin 8. ( Chen, K; Peng, K; Tang, B; Wang, Q; Wang, Z; Yang, D; Yang, P; Yang, Y, 2020)
"Chlorpyrifos (CPF) is one of the predominant water pollutants associated with inflammation and immunodepression in aquatic animals."3.96The impact of menthol essential oil against inflammation, immunosuppression, and histopathological alterations induced by chlorpyrifos in Nile tilapia. ( Abdel-Latif, HMR; Abdel-Razek, MAS; Abdel-Razik, NI; Abdo, SE; Amer, AA; Dawood, MAO; El-Salam Metwally, A; Elkomy, AH; Gewaily, MS; Paray, BA; Soliman, AA, 2020)
"To investigate the role of mammalian target of rapamycin (mTOR) activation in menthol-induced expression of airway inflammation- related factors in human bronchial epithelial cells and explore its mechanism."3.91[Role of mammalian target of rapamycin activation in menthol-induced expressions of airway inflammation-related factors in human bronchial epithelial cells ( Chen, H; Li, M, 2019)
" To evaluate THEDES anti-CRC therapeutic potential, their physico-chemical properties, bioavailability and bioactivity, were explored."1.72Selective terpene based therapeutic deep eutectic systems against colorectal cancer. ( Duarte, ARC; Miguel Castro, M; Oliveira, F; Paiva, A; Pereira, J; Rita Jesus, A; Santos, F, 2022)
"Chronic inflammation is a potential systemic risk factor for many bladder dysfunctions, including interstitial cystitis (IC)."1.48Menthol, a unique urinary volatile compound, is associated with chronic inflammation in interstitial cystitis. ( Cho, E; Kim, J; Lee, MY; Sairam, V; Shahid, M; Valdiviez, L; Yeon, A; You, S, 2018)
"Pretreatment with menthol at various doses significantly suppressed tumor formation and growth, and markedly reduced tumor incidence and volume."1.42Chemopreventive efficacy of menthol on carcinogen-induced cutaneous carcinoma through inhibition of inflammation and oxidative stress in mice. ( Cao, Y; Chen, C; Fan, F; Lin, C; Liu, Z; Lu, Y; Shan, Y; Shen, C; Sun, L; Tao, Y; Wang, A; Wang, S; Wei, Z; Wu, H; Zheng, S; Zhu, P, 2015)
"Arachidonic acid metabolism was assessed by measuring LTB subset4 and PGE subset2 as indicators for both the lipoxygenase and the cyclooxygenase pathways respectively."1.30The anti-inflammatory activity of L-menthol compared to mint oil in human monocytes in vitro: a novel perspective for its therapeutic use in inflammatory diseases. ( Juergens, UR; Stöber, M; Vetter, H, 1998)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.00)18.7374
1990's3 (15.00)18.2507
2000's2 (10.00)29.6817
2010's5 (25.00)24.3611
2020's8 (40.00)2.80

Authors

AuthorsStudies
Pereira, J1
Miguel Castro, M1
Santos, F1
Rita Jesus, A1
Paiva, A1
Oliveira, F1
Duarte, ARC1
Wu, H2
Zhou, H1
Zhang, W1
Jin, P1
Shi, Q1
Miao, Z1
Wang, H1
Zha, Z1
Su, YH1
Lin, JY1
Cheng, H3
An, X3
Rachitha, P1
Krupashree, K1
Jayashree, GV1
Raghavendra, VB1
Pal, A1
Chinnathambi, A1
Alharbi, SA1
Shanmuganathan, R1
Karuppusamy, I1
Brindhadevi, K1
Wang, Q1
Yang, Y2
Chen, K1
Tang, B1
Peng, K1
Wang, Z1
Yang, P1
Yang, D1
Alves, QL1
de Jesus, RLC1
Silva, DF1
Chen, H1
Li, M1
Dawood, MAO1
El-Salam Metwally, A1
Elkomy, AH1
Gewaily, MS1
Abdo, SE1
Abdel-Razek, MAS1
Soliman, AA1
Amer, AA1
Abdel-Razik, NI1
Abdel-Latif, HMR1
Paray, BA1
Shahid, M1
Lee, MY1
Yeon, A1
Cho, E1
Sairam, V1
Valdiviez, L1
You, S1
Kim, J1
Liu, B1
Fan, L1
Balakrishna, S1
Sui, A1
Morris, JB1
Jordt, SE1
Liu, Z1
Shen, C1
Tao, Y1
Wang, S1
Wei, Z1
Cao, Y1
Fan, F1
Lin, C1
Shan, Y1
Zhu, P1
Sun, L1
Chen, C1
Wang, A1
Zheng, S1
Lu, Y1
Patel, NA1
Patel, NJ1
Patel, RP1
Journigan, VB1
Zaveri, NT1
Linte, RM1
Ciobanu, C1
Reid, G1
Babes, A1
Juergens, UR2
Stöber, M2
Vetter, H2
Beuscher, N1
Kietzmann, M1
Bien, E1
Champeroux, P1
Wochna-Sobańska, M1
Yesilsoy, C1
Koren, LZ1
Morse, DR1
Kobayashi, C1

Reviews

2 reviews available for menthol and Inflammation

ArticleYear
Cold stimuli, hot topic: An updated review on the biological activity of menthol in relation to inflammation.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Anti-Inflammatory Agents; Biomarkers; Cytokines; Humans; Inflammation; Menthol

2022
Cold stimuli, hot topic: An updated review on the biological activity of menthol in relation to inflammation.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Anti-Inflammatory Agents; Biomarkers; Cytokines; Humans; Inflammation; Menthol

2022
Cold stimuli, hot topic: An updated review on the biological activity of menthol in relation to inflammation.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Anti-Inflammatory Agents; Biomarkers; Cytokines; Humans; Inflammation; Menthol

2022
Cold stimuli, hot topic: An updated review on the biological activity of menthol in relation to inflammation.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Anti-Inflammatory Agents; Biomarkers; Cytokines; Humans; Inflammation; Menthol

2022
TRPM8 ion channel ligands for new therapeutic applications and as probes to study menthol pharmacology.
    Life sciences, 2013, Mar-19, Volume: 92, Issue:8-9

    Topics: Animals; Antineoplastic Agents; Cold Temperature; Female; Humans; Inflammation; Ligands; Male; Menth

2013

Other Studies

18 other studies available for menthol and Inflammation

ArticleYear
Selective terpene based therapeutic deep eutectic systems against colorectal cancer.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2022, Volume: 175

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Caspase 3; Colorectal Neoplasms; Humans; Ibuprofen; Inflamm

2022
Three birds with one stone: co-encapsulation of diclofenac and DL-menthol for realizing enhanced energy deposition, glycolysis inhibition and anti-inflammation in HIFU surgery.
    Journal of nanobiotechnology, 2022, May-06, Volume: 20, Issue:1

    Topics: Diclofenac; Glycolysis; High-Intensity Focused Ultrasound Ablation; Humans; Inflammation; Menthol

2022
Menthone supplementation protects from allergic inflammation in the lungs of asthmatic mice.
    European journal of pharmacology, 2022, Sep-15, Volume: 931

    Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Dietary Supplements; Disease Models, Anima

2022
T-2 toxin induces dermal inflammation and toxicity in mice: The healing potential of menthol.
    Environmental research, 2023, 07-01, Volume: 228

    Topics: Allergens; Animals; Inflammation; Menthol; Mice; Molecular Docking Simulation; Skin; T-2 Toxin

2023
Dietary Menthol Attenuates Inflammation and Cardiac Remodeling After Myocardial Infarction via the Transient Receptor Potential Melastatin 8.
    American journal of hypertension, 2020, 03-13, Volume: 33, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Diet; Disease Models, Animal; Fibrosis; Hemodynamics; Inflammatio

2020
Beneficial Effects Induced by TRPM8 Channels Activation to Treat Myocardial Infarction.
    American journal of hypertension, 2020, 03-13, Volume: 33, Issue:3

    Topics: Humans; Inflammation; Membrane Proteins; Menthol; Myocardial Infarction; TRPM Cation Channels; Ventr

2020
[Role of mammalian target of rapamycin activation in menthol-induced expressions of airway inflammation-related factors in human bronchial epithelial cells
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2019, Nov-30, Volume: 39, Issue:11

    Topics: Epithelial Cells; Humans; Inflammation; Interleukin-1beta; Menthol; Sirolimus; TOR Serine-Threonine

2019
The impact of menthol essential oil against inflammation, immunosuppression, and histopathological alterations induced by chlorpyrifos in Nile tilapia.
    Fish & shellfish immunology, 2020, Volume: 102

    Topics: Animal Feed; Animals; Chlorpyrifos; Cichlids; Diet; Dietary Supplements; Dose-Response Relationship,

2020
Menthol, a unique urinary volatile compound, is associated with chronic inflammation in interstitial cystitis.
    Scientific reports, 2018, Jul-18, Volume: 8, Issue:1

    Topics: Animals; Antipruritics; Case-Control Studies; Cells, Cultured; Chronic Disease; Cystitis, Interstiti

2018
TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain.
    Pain, 2013, Volume: 154, Issue:10

    Topics: Acute Pain; Analgesia; Animals; Cells, Cultured; Inflammation; Male; Menthol; Mice; Mice, Inbred C57

2013
Chemopreventive efficacy of menthol on carcinogen-induced cutaneous carcinoma through inhibition of inflammation and oxidative stress in mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2015, Volume: 82

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anticarcinogenic Agents; Carcino

2015
Formulation and evaluation of curcumin gel for topical application.
    Pharmaceutical development and technology, 2009, Volume: 14, Issue:1

    Topics: Acrylates; Administration, Topical; Animals; Anti-Infective Agents, Local; Calorimetry, Differential

2009
Desensitization of cold- and menthol-sensitive rat dorsal root ganglion neurones by inflammatory mediators.
    Experimental brain research, 2007, Volume: 178, Issue:1

    Topics: Analgesia; Animals; Ankyrins; Antipruritics; Calcium Channels; Cells, Cultured; Cold Temperature; Cy

2007
Inhibition of cytokine production and arachidonic acid metabolism by eucalyptol (1.8-cineole) in human blood monocytes in vitro.
    European journal of medical research, 1998, Nov-17, Volume: 3, Issue:11

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Asthma; Cyclohexanols; Cytokines;

1998
Interference of myrtol standardized with inflammatory and allergic mediators.
    Arzneimittel-Forschung, 1998, Volume: 48, Issue:10

    Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Basophils; Cattle; Cyclohexanols; Dinoprosto

1998
The anti-inflammatory activity of L-menthol compared to mint oil in human monocytes in vitro: a novel perspective for its therapeutic use in inflammatory diseases.
    European journal of medical research, 1998, Dec-16, Volume: 3, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Dinoprostone; Drug Evaluation, Preclinica

1998
[Experimental studies of the inflammation-inducing action of various agents used in the treatment of pulp diseases in deciduous teeth].
    Czasopismo stomatologiczne, 1987, Volume: 40, Issue:2

    Topics: Animals; Anti-Infective Agents, Local; Camphor; Chlorophenols; Disinfectants; Drug Combinations; For

1987
A comparative tissue toxicity evaluation of established and newer root canal sealers.
    Oral surgery, oral medicine, and oral pathology, 1988, Volume: 65, Issue:4

    Topics: Animals; Calcinosis; Calcium Hydroxide; Drug Combinations; Eugenol; Guinea Pigs; Gutta-Percha; Hydro

1988