Page last updated: 2024-10-21

menthol and Hypertension

menthol has been researched along with Hypertension in 5 studies

Menthol: A monoterpene cyclohexanol produced from mint oils.

Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Research Excerpts

ExcerptRelevanceReference
"Long-term dietary menthol treatment targeting and preserving mitochondrial function may represent a nonpharmaceutical measure for environmental noxious cold-induced hypertension."3.85Activation of Transient Receptor Potential Melastatin Subtype 8 Attenuates Cold-Induced Hypertension Through Ameliorating Vascular Mitochondrial Dysfunction. ( Cui, Y; Gao, P; Li, L; Li, Y; Lin, S; Liu, D; Lu, Z; Wang, B; Wei, X; Xiong, S; Zhang, H; Zhao, Z; Zhu, Z, 2017)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Voronova, IP1
Khramova, GM1
Evtushenko, AA1
Kozyreva, TV1
Hooper, JS1
Taylor-Clark, TE1
Xiong, S2
Wang, B1
Lin, S1
Zhang, H1
Li, Y1
Wei, X2
Cui, Y1
Lu, Z1
Gao, P1
Li, L2
Zhao, Z1
Liu, D2
Zhu, Z3
Sun, J1
Yang, T1
Wang, P1
Ma, S1
Pu, Y1
Zhao, Y1
Palop Larrea, V1
López-Martín, JM1
Pastor Navarro, MC1
Martínez Mir, I1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Double-Blind, Placebo Control Trial Comparing Effects and Safety of DANSHU Capsule(Menthol) and Placebo on Blood Pressure and Metabolic Parameters in Prehypertensive and Mild Hypertensive Patients[NCT01408446]Phase 2/Phase 336 participants (Actual)Interventional2012-08-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for menthol and Hypertension

ArticleYear
Activation of cold-sensing transient receptor potential melastatin subtype 8 antagonizes vasoconstriction and hypertension through attenuating RhoA/Rho kinase pathway.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:6

    Topics: Animals; Blood Pressure; Blotting, Western; Calcium; Capsules; Cells, Cultured; Cold Temperature; Fe

2014

Other Studies

4 other studies available for menthol and Hypertension

ArticleYear
Effect of Skin Ion Channel TRPM8 Activation by Cold and Menthol on Thermoregulation and the Expression of Genes of Thermosensitive TRP Ion Channels in the Hypothalamus of Hypertensive Rats.
    International journal of molecular sciences, 2022, May-29, Volume: 23, Issue:11

    Topics: Animals; Body Temperature Regulation; Cold Temperature; Hypertension; Hypothalamus; Menthol; Rats; T

2022
Irritant-evoked reflex tachyarrhythmia in spontaneously hypertensive rats is reduced by inhalation of TRPM8 agonists l-menthol and WS-12.
    Journal of applied physiology (Bethesda, Md. : 1985), 2023, 02-01, Volume: 134, Issue:2

    Topics: Animals; Bradycardia; Cardiovascular Diseases; Hypertension; Irritants; Lung; Mammals; Menthol; Rats

2023
Activation of Transient Receptor Potential Melastatin Subtype 8 Attenuates Cold-Induced Hypertension Through Ameliorating Vascular Mitochondrial Dysfunction.
    Journal of the American Heart Association, 2017, Aug-02, Volume: 6, Issue:8

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Calcium; Cell Respiration; Cells, Cultured; Cold T

2017
[Pastillas Juanola and arterial hypertension].
    Atencion primaria, 1997, Sep-30, Volume: 20, Issue:5

    Topics: Adult; Contraceptives, Oral, Combined; Contraceptives, Oral, Synthetic; Cyclohexanols; Drug Combinat

1997