Page last updated: 2024-10-21

menthol and Amphetamine-Related Disorders

menthol has been researched along with Amphetamine-Related Disorders in 1 studies

Menthol: A monoterpene cyclohexanol produced from mint oils.

Amphetamine-Related Disorders: Disorders related or resulting from use of amphetamines.

Research Excerpts

ExcerptRelevanceReference
"Smoking cessation was assessed via self-report and carbon monoxide levels."2.78A tale of two stimulants: mentholated cigarettes may play a role in cocaine, but not methamphetamine, dependence. ( Adinoff, B; Brigham, GS; Gardin, JG; Ghitza, U; Lewis, DF; Sonne, SC; Theobald, J; Winhusen, TM, 2013)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Winhusen, TM1
Adinoff, B1
Lewis, DF1
Brigham, GS1
Gardin, JG1
Sonne, SC1
Theobald, J1
Ghitza, U1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Smoking-Cessation and Stimulant Treatment (S-CAST): Evaluation of the Impact of Concurrent Outpatient Smoking-Cessation and Stimulant Treatment on Stimulant-Dependence Outcomes[NCT01077024]Phase 3538 participants (Actual)Interventional2010-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Four Week Continuous Smoking Abstinence

A combination of daily self-reported smoking data and weekly carbon monoxide levels were used to determine continuous abstinence during post-quit days 15 - 42. (NCT01077024)
Timeframe: Post-quit days 15-42

Interventionpercentage of participants (Number)
Smoking-cessation Treatment + Substance Treatment as Usual6.7
Substance-treatment as Usual0.0

Point-prevalence Abstinence (Smoking Outcome)

point-prevalence abstinence defined as not smoking in the previous seven days based on self-report and confirmed with a Carbon Monoxide (CO) level ≤ 8 ppm (NCT01077024)
Timeframe: Week 10 assessment

Interventionpercentage of participants (Number)
Smoking-cessation Treatment + Substance Treatment as Usual25.5
Substance-treatment as Usual2.2

Point-prevalence Abstinence (Smoking Outcome) 3 Month Visit

point-prevalence abstinence defined as not smoking in the previous seven days based on self-report and confirmed with a Carbon Monoxide (CO) level ≤ 8 ppm (NCT01077024)
Timeframe: 3- month follow-up visits

Interventionpercentage of participants (Number)
Smoking-cessation Treatment + Substance Treatment as Usual19.1
Substance-treatment as Usual3.0

Point-prevalence Abstinence (Smoking Outcome) 6 Month Visit

point-prevalence abstinence defined as not smoking in the previous seven days based on self-report and confirmed with a Carbon Monoxide (CO) level ≤ 8 ppm (NCT01077024)
Timeframe: 6 month visit

Interventionpercentage of participants (Number)
Smoking-cessation Treatment + Substance Treatment as Usual13.1
Substance-treatment as Usual3.7

Stimulant-free Results at 3-month Visit

At the 3-month follow-up visit, percentage of participants with a negative urine drug screen for stimulant use and no stimulant use days reported during the past 28 days based on Timeline Follow-back. (NCT01077024)
Timeframe: 3-month follow-up visit

Interventionpercentage of participants (Number)
Smoking-cessation Treatment + Substance Treatment as Usual74.3
Substance-treatment as Usual68.8

Stimulant-free Results at 6-month Visit

At the 6-month follow-up visit, percentage of participants with a negative urine drug screen for stimulant use and no stimulant use days reported during the past 28 days based on Timeline Follow-back. (NCT01077024)
Timeframe: 6 - months follow-up visit

Interventionpercentage of participants (Number)
Smoking-cessation Treatment + Substance Treatment as Usual69.5
Substance-treatment as Usual71.6

Stimulant-free Weeks Assessed by Self-report and Twice-weekly Urine Drug Screens

Stimulant-free week results (no cocaine, methamphetamine and amphetamine use) were obtained by combining the urine drug screens (UDS) and the self-reported Timeline Follow-Back (TLFB). At the group level, this outcome translates into the percentage of weeks in each study arm that are stimulant-free. (NCT01077024)
Timeframe: Week 16

Interventionpercentage of weeks (Number)
Smoking-cessation Treatment + Substance Treatment as Usual77.7
Substance-treatment as Usual78.0

Trials

1 trial available for menthol and Amphetamine-Related Disorders

ArticleYear
A tale of two stimulants: mentholated cigarettes may play a role in cocaine, but not methamphetamine, dependence.
    Drug and alcohol dependence, 2013, Dec-15, Volume: 133, Issue:3

    Topics: Adult; Amphetamine-Related Disorders; Behavior, Addictive; Cocaine-Related Disorders; Female; Humans

2013