menotropins and Pleural-Effusion

Isolated acute unilateral pleural effusion has twice been reported as the only symptom of ovarian hyperstimulation syndrome (Kingsland et al, 1989; Jewelewicz and Vande Wiele, 1975). The pathogenesis of this disorder is not fully understood and the presence of an isolated pleural effusion lends support to the role of systemic factors rather than purely the transudation of fluid from grossly enlarged ovaries in the progression of this disease. This article describes a second case of an isolated pleural effusion following in-vitro fertilization and embryo transfer.

Topics: Adult; Buserelin; Embryo Transfer; Female; Fertilization in Vitro; Humans; Infertility, Male; Male; Menotropins; Ovarian Hyperstimulation Syndrome; Pleural Effusion

To describe a patient with severe ovarian hyperstimulation syndrome (OHSS) demonstrating a beneficial result of reduction in abdominal ascites with a chest tube placed for bilateral pleural effusions.. Case report.. Academic hospital.. A 28-year-old white female with primary infertility on hMG (Pergonal; Serono Laboratories, Randolph, MA) therapy.. Intravenous fluids, lasix, and albumin were administered for correction of laboratory abnormalities, including hemoconcentration, hypoalbuminemia, and leukocytosis. A chest tube was placed for treatment of pleural effusions.. Laboratory values of hematologic measures and electrolytes. Resolution of pleural effusions and abdominal ascites as determined by chest roentgenogram and physical examination.. Treatment of OHSS with intravenous fluids, lasix, and albumin corrected the hemoconcentration, hypoalbuminemia, and leukocytosis associated with OHSS. Placement of a chest tube corrected the pleural effusions and abdominal ascites.. This case report demonstrates a beneficial result of reduction in abdominal ascites by a chest tube placed for pleural effusions.

Topics: Adult; Ascites; Chest Tubes; Drainage; Female; Fluid Therapy; Humans; Infertility, Female; Menotropins; Ovarian Hyperstimulation Syndrome; Pleural Effusion

The ovarian hyperstimulation syndrome is the most serious complication following ovulation induction. It is assuming greater clinical importance now that the indication for ovulation induction is no longer limited to anovulatory women but expands to other infertility problems. In its most severe manifestation the ovarian hyperstimulation syndrome consists of massive ovarian enlargement with multiple cysts, hemoconcentration, ascites, and pleural and pericardial effusion. There is no specific treatment and a reduction in the incidence of this iatrogenic syndrome can be achieved only by preventive measures.

Topics: Adult; Ascites; Female; Humans; Hypertrophy; Iatrogenic Disease; Menotropins; Ovarian Cysts; Ovary; Ovulation Induction; Pleural Effusion; Syndrome

Ovarian hyperstimulation syndrome occurred in a 32-year-old woman who presented with symptoms from a large unilateral pleural effusion which was the predominant feature in her case. The aetiology of the effusion was initially uncertain in view of the relative absence of ascites suggesting that the effusion arose because of a primary pleural abnormality.

Topics: Adult; Chorionic Gonadotropin; Drug Therapy, Combination; Female; Humans; Infertility, Female; Menotropins; Pleural Effusion

An iatrogenic disease resulting from the induction of ovulation is described. It would appear that it is uncommon in southern Africa.

Topics: Adult; Ascites; Female; Humans; Menotropins; Ovarian Diseases; Ovulation Induction; Pleural Effusion

Plasma prolactin, estradiol, progesterone, and testosterone, but not HCG-beta levels, were higher in a patient who developed the ovarian hyperstimulation syndrome while undergoing ovulation induction with human gonadotropins than in two other women who also became pregnant after similar treatment without complications. These results suggest that hyperprolactinema, in association with elevated ovarian steroid levels, may be factors in the pathogenesis of this disorder.

Topics: Blood Proteins; Chorionic Gonadotropin; Estradiol; Female; Humans; Menotropins; Ovarian Diseases; Ovulation Induction; Pleural Effusion; Pregnancy; Progesterone; Prolactin; Proteins; Stimulation, Chemical; Syndrome; Testosterone

Topics: Animals; Ascitic Fluid; Chlorpheniramine; Disease Models, Animal; Female; Humans; Menotropins; Ovarian Cysts; Ovarian Diseases; Ovary; Pleural Effusion; Rabbits