menatetrenone has been researched along with Osteonecrosis* in 1 studies
1 other study(ies) available for menatetrenone and Osteonecrosis
| Article | Year |
|---|---|
Menaquinone-4 prevents medication-related osteonecrosis of the jaw through the SIRT1 signaling-mediated inhibition of cellular metabolic stresses-induced osteoblast apoptosis.
Long-term usage of bisphosphonates, especially zoledronic acid (ZA), induces osteogenesis disorders and medication-related osteonecrosis of the jaw (MRONJ) in patients, thereby contributing to the destruction of bone remodeling and the continuous progression of osteonecrosis. Menaquinone-4 (MK-4), a specific vitamin K Topics: Animals; Apoptosis; Bone Density Conservation Agents; Diphosphonates; Mice; Osteoblasts; Osteonecrosis; Signal Transduction; Sirtuin 1; Stress, Physiological; Zoledronic Acid | 2023 |