menaquinone-6 and Drug-Hypersensitivity

Vitamin (V) K deficiency may cause severe bleeding tendencies, which necessitates extreme caution. We report a case of a 30-year-old man diagnosed with VK deficiency of unknown etiology. He was treated with intravenous menatetrenone three times a week in an outpatient setting for about 1 year and 9 months. Eventually, he developed an allergic reaction to intravenous menatetrenone and was under steroid therapy. In order to reduce his hospital visits and discontinue steroid use, the pharmacist proposed to change the method of menatetrenone administration from intravenous to oral (high dose). The change in treatment method has greatly improved the patient's quality of life.

Topics: Administration, Intravenous; Administration, Oral; Adult; Drug Hypersensitivity; Hemostatics; Humans; Male; Quality of Life; Steroids; Vitamin K 2; Vitamin K Deficiency