memantine has been researched along with Spasms, Infantile in 3 studies
Spasms, Infantile: An epileptic syndrome characterized by the triad of infantile spasms, hypsarrhythmia, and arrest of psychomotor development at seizure onset. The majority present between 3-12 months of age, with spasms consisting of combinations of brief flexor or extensor movements of the head, trunk, and limbs. The condition is divided into two forms: cryptogenic (idiopathic) and symptomatic (secondary to a known disease process such as intrauterine infections; nervous system abnormalities; BRAIN DISEASES, METABOLIC, INBORN; prematurity; perinatal asphyxia; TUBEROUS SCLEROSIS; etc.). (From Menkes, Textbook of Child Neurology, 5th ed, pp744-8)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Because both individuals' seizures had proven refractory to conventional antiepileptic medications, the sensitivity of mutant NMDARs to FDA-approved NMDAR antagonists was evaluated." | 1.43 | GRIN2D Recurrent De Novo Dominant Mutation Causes a Severe Epileptic Encephalopathy Treatable with NMDA Receptor Channel Blockers. ( Aizenman, E; Brueckner, F; Chen, W; Chiavacci, R; Elsen, G; Falk, MJ; Hakonarson, H; Hedrich, UB; Hörtnagel, K; Hu, C; Kosobucki, GJ; Kusumoto, H; Lemke, JR; Li, D; Marsh, ED; McCormick, EM; Naase, C; Ortiz-Gonzalez, XR; Schulien, AJ; Tankovic, A; Tian, L; Traynelis, SF; von Stülpnagel-Steinbeis, C; Yuan, H, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Chidambaram, S | 1 |
| Manokaran, RK | 1 |
| Tang, S | 1 |
| Terzic, B | 1 |
| Wang, IJ | 1 |
| Sarmiento, N | 1 |
| Sizov, K | 1 |
| Cui, Y | 1 |
| Takano, H | 1 |
| Marsh, ED | 2 |
| Zhou, Z | 1 |
| Coulter, DA | 1 |
| Li, D | 1 |
| Yuan, H | 1 |
| Ortiz-Gonzalez, XR | 1 |
| Tian, L | 1 |
| McCormick, EM | 1 |
| Kosobucki, GJ | 1 |
| Chen, W | 1 |
| Schulien, AJ | 1 |
| Chiavacci, R | 1 |
| Tankovic, A | 1 |
| Naase, C | 1 |
| Brueckner, F | 1 |
| von Stülpnagel-Steinbeis, C | 1 |
| Hu, C | 1 |
| Kusumoto, H | 1 |
| Hedrich, UB | 1 |
| Elsen, G | 1 |
| Hörtnagel, K | 1 |
| Aizenman, E | 1 |
| Lemke, JR | 1 |
| Hakonarson, H | 1 |
| Traynelis, SF | 1 |
| Falk, MJ | 1 |
3 other studies available for memantine and Spasms, Infantile
| Article | Year |
|---|---|
Favorable Response to "Memantine" in a Child with GRIN2B Epileptic Encephalopathy.
Topics: Child; Humans; Infant; Male; Memantine; Mutation; Receptors, N-Methyl-D-Aspartate; Seizures; Spasms, | 2022 |
Altered NMDAR signaling underlies autistic-like features in mouse models of CDKL5 deficiency disorder.
Topics: Animals; Behavior, Animal; Codon, Nonsense; Disease Models, Animal; Epileptic Syndromes; Excitatory | 2019 |
GRIN2D Recurrent De Novo Dominant Mutation Causes a Severe Epileptic Encephalopathy Treatable with NMDA Receptor Channel Blockers.
Topics: Amino Acid Sequence; Base Sequence; Cell Death; Child; Dendrites; DNA Mutational Analysis; Electroen | 2016 |