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memantine and Retinal Diseases

memantine has been researched along with Retinal Diseases in 4 studies

Retinal Diseases: Diseases involving the RETINA.

Research Excerpts

ExcerptRelevanceReference
"To determine whether intraocular pressure (IOP) elevation alters OPA1 expression and triggers OPA1 release, as well as whether the uncompetitive N-methyl-d-aspartate (NMDA) glutamate receptor antagonist memantine blocks OPA1 release and subsequent apoptotic cell death in glaucomatous DBA/2J mouse retina."7.75Memantine blocks mitochondrial OPA1 and cytochrome c release and subsequent apoptotic cell death in glaucomatous retina. ( Angert, M; Duong-Polk, KX; Ellisman, MH; Ju, WK; Kim, KY; Lindsey, JD; Weinreb, RN, 2009)
"To determine whether intraocular pressure (IOP) elevation alters OPA1 expression and triggers OPA1 release, as well as whether the uncompetitive N-methyl-d-aspartate (NMDA) glutamate receptor antagonist memantine blocks OPA1 release and subsequent apoptotic cell death in glaucomatous DBA/2J mouse retina."3.75Memantine blocks mitochondrial OPA1 and cytochrome c release and subsequent apoptotic cell death in glaucomatous retina. ( Angert, M; Duong-Polk, KX; Ellisman, MH; Ju, WK; Kim, KY; Lindsey, JD; Weinreb, RN, 2009)
"Memantine is a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist that was initially indicated for the treatment of moderate to severe Alzheimer's disease."2.72Memantine and its benefits for cancer, cardiovascular and neurological disorders. ( Abbaszadeh, S; Janssen, PML; Shafiei-Irannejad, V; Soraya, H, 2021)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Shafiei-Irannejad, V1
Abbaszadeh, S1
Janssen, PML1
Soraya, H1
Ito, Y1
Nakamura, S1
Tanaka, H1
Shimazawa, M1
Araie, M1
Hara, H1
Ju, WK1
Kim, KY1
Angert, M1
Duong-Polk, KX1
Lindsey, JD1
Ellisman, MH1
Weinreb, RN1
Lagrèze, WA1

Reviews

1 review available for memantine and Retinal Diseases

ArticleYear
Memantine and its benefits for cancer, cardiovascular and neurological disorders.
    European journal of pharmacology, 2021, Nov-05, Volume: 910

    Topics: Animals; Cardiovascular Diseases; Excitatory Amino Acid Antagonists; Humans; Inflammation; Memantine

2021

Other Studies

3 other studies available for memantine and Retinal Diseases

ArticleYear
Memantine protects against secondary neuronal degeneration in lateral geniculate nucleus and superior colliculus after retinal damage in mice.
    CNS neuroscience & therapeutics, 2008,Fall, Volume: 14, Issue:3

    Topics: Animals; Cell Death; Disease Models, Animal; Drug Administration Schedule; Excitatory Amino Acid Ant

2008
Memantine blocks mitochondrial OPA1 and cytochrome c release and subsequent apoptotic cell death in glaucomatous retina.
    Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:2

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cell Survival; Cytochromes c; Dyn

2009
[Neuroprotection. Bases and possibilities of a future clinical use].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2001, Volume: 98, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Apoptosis; Brimonidine Tartrate; Clinical Trials as Topic; Disea

2001