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memantine and Peripheral Nerve Diseases

memantine has been researched along with Peripheral Nerve Diseases in 6 studies

Research Excerpts

ExcerptRelevanceReference
"Memantine hydrochloride, an NMDA antagonist, was launched in Germany by Merz in 1989 for the treatment of dementia, an indication for which development was continuing in other markets."4.81Memantine. Merz. ( Kilpatrick, GJ; Tilbrook, GS, 2002)
"Systemic treatment with the N-methyl-D-aspartate (NMDA) antagonist memantine (MEM) resulted in a decrease in mechanical hyperalgesia and mechanical allodynia in neuropathic rats."3.69Treatment with the NMDA antagonist memantine attenuates nociceptive responses to mechanical stimulation in neuropathic rats. ( Carlton, SM; Hargett, GL, 1995)
"It is still unknown whether neuropathic pain could relate to behavioral and neurochemical alterations in the central nervous system."1.35Effect of memantine on the levels of neuropeptides and microglial cells in the brain regions of rats with neuropathic pain. ( Chikuma, T; Kato, T; Muramatsu, M; Takeda, K, 2009)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's5 (83.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takeda, K1
Muramatsu, M1
Chikuma, T1
Kato, T1
Nakazato, E1
Kato, A1
Watanabe, S1
Schifitto, G1
Yiannoutsos, CT1
Simpson, DM1
Marra, CM1
Singer, EJ1
Kolson, DL1
Nath, A1
Berger, JR1
Navia, B1
Carlton, SM1
Hargett, GL1
Suzuki, R1
Matthews, EA1
Dickenson, AH1
Kilpatrick, GJ1
Tilbrook, GS1

Reviews

1 review available for memantine and Peripheral Nerve Diseases

ArticleYear
Memantine. Merz.
    Current opinion in investigational drugs (London, England : 2000), 2002, Volume: 3, Issue:5

    Topics: Animals; Clinical Trials as Topic; Dementia; Excitatory Amino Acid Antagonists; Glaucoma; Humans; Me

2002

Trials

1 trial available for memantine and Peripheral Nerve Diseases

ArticleYear
A placebo-controlled study of memantine for the treatment of human immunodeficiency virus-associated sensory neuropathy.
    Journal of neurovirology, 2006, Volume: 12, Issue:4

    Topics: Adult; Excitatory Amino Acid Antagonists; Female; HIV; HIV Infections; Humans; Male; Memantine; Peri

2006

Other Studies

4 other studies available for memantine and Peripheral Nerve Diseases

ArticleYear
Effect of memantine on the levels of neuropeptides and microglial cells in the brain regions of rats with neuropathic pain.
    Journal of molecular neuroscience : MN, 2009, Volume: 39, Issue:3

    Topics: Analgesics; Animals; Brain; CD11 Antigens; Disease Models, Animal; Excitatory Amino Acid Antagonists

2009
Brain but not spinal NR2B receptor is responsible for the anti-allodynic effect of an NR2B subunit-selective antagonist CP-101,606 in a rat chronic constriction injury model.
    Pharmacology, 2005, Volume: 73, Issue:1

    Topics: Analgesics; Animals; Brain Chemistry; Constriction; Excitatory Amino Acid Antagonists; Injections, I

2005
Treatment with the NMDA antagonist memantine attenuates nociceptive responses to mechanical stimulation in neuropathic rats.
    Neuroscience letters, 1995, Sep-29, Volume: 198, Issue:2

    Topics: Analgesics; Animals; Drug Implants; Excitatory Amino Acid Antagonists; Hyperalgesia; Injections, Int

1995
Comparison of the effects of MK-801, ketamine and memantine on responses of spinal dorsal horn neurones in a rat model of mononeuropathy.
    Pain, 2001, Volume: 91, Issue:1-2

    Topics: Animals; Dizocilpine Maleate; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagon

2001