memantine has been researched along with Optic Neuritis in 4 studies
Optic Neuritis: Inflammation of the optic nerve. Commonly associated conditions include autoimmune disorders such as MULTIPLE SCLEROSIS, infections, and granulomatous diseases. Clinical features include retro-orbital pain that is aggravated by eye movement, loss of color vision, and contrast sensitivity that may progress to severe visual loss, an afferent pupillary defect (Marcus-Gunn pupil), and in some instances optic disc hyperemia and swelling. Inflammation may occur in the portion of the nerve within the globe (neuropapillitis or anterior optic neuritis) or the portion behind the globe (retrobulbar neuritis or posterior optic neuritis).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the effect of memantine on axonal loss and visual function during the course of optic neuritis (ON)." | 9.16 | Memantine for axonal loss of optic neuritis. ( Adelpour, M; Esfahani, MR; Fard, MA; Harandi, ZA; Merat, H; Momeni, A; Movasat, M; Nikdel, M, 2012) |
| "To determine the effect of memantine on axonal loss and visual function during the course of optic neuritis (ON)." | 5.16 | Memantine for axonal loss of optic neuritis. ( Adelpour, M; Esfahani, MR; Fard, MA; Harandi, ZA; Merat, H; Momeni, A; Movasat, M; Nikdel, M, 2012) |
| "Optic neuritis is a common clinical manifestation of the chronic inflammatory CNS disease multiple sclerosis that can result in persistent visual impairment caused by degeneration of optic nerve axons and apoptosis of retinal ganglion cells (RGCs)." | 1.40 | N-methyl-D-aspartate receptor blockade is neuroprotective in experimental autoimmune optic neuritis. ( Cavalié, A; Diem, R; Fairless, R; Heine, K; Sühs, KW; Williams, SK, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Motamedi, D | 1 |
| Mayeli, M | 1 |
| Shafie, M | 1 |
| Sattarpour, R | 1 |
| Jazani, MR | 1 |
| Tafakhori, A | 1 |
| Sarraf, P | 1 |
| Sühs, KW | 1 |
| Fairless, R | 1 |
| Williams, SK | 1 |
| Heine, K | 1 |
| Cavalié, A | 1 |
| Diem, R | 1 |
| Esfahani, MR | 1 |
| Harandi, ZA | 1 |
| Movasat, M | 1 |
| Nikdel, M | 1 |
| Adelpour, M | 1 |
| Momeni, A | 1 |
| Merat, H | 1 |
| Fard, MA | 1 |
| Lagrèze, WA | 1 |
2 trials available for memantine and Optic Neuritis
| Article | Year |
|---|---|
Memantine administration in patients with optic neuritis: a double blind randomized clinical trial.
Topics: Evoked Potentials, Visual; Humans; Memantine; Optic Neuritis; Retina; Tomography, Optical Coherence | 2022 |
Memantine for axonal loss of optic neuritis.
Topics: Adolescent; Adult; Axons; Contrast Sensitivity; Double-Blind Method; Evoked Potentials, Visual; Exci | 2012 |
2 other studies available for memantine and Optic Neuritis
| Article | Year |
|---|---|
N-methyl-D-aspartate receptor blockade is neuroprotective in experimental autoimmune optic neuritis.
Topics: Animals; Animals, Newborn; Calcium; Cells, Cultured; Cytokines; Dizocilpine Maleate; Female; Memanti | 2014 |
[Neuroprotection. Bases and possibilities of a future clinical use].
Topics: Adrenergic alpha-Agonists; Animals; Apoptosis; Brimonidine Tartrate; Clinical Trials as Topic; Disea | 2001 |