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memantine and Ocular Hypertension

memantine has been researched along with Ocular Hypertension in 5 studies

Ocular Hypertension: A condition in which the intraocular pressure is elevated above normal and which may lead to glaucoma.

Research Excerpts

ExcerptRelevanceReference
"To determine, using electrophysiological measures of visual system function, whether oral daily dosing of memantine is both safe and effective to reduce the injury associated with experimental glaucoma in primates."7.72Efficacy and safety of memantine treatment for reduction of changes associated with experimental glaucoma in monkey, I: Functional measures. ( Chun, T; Hare, WA; Lai, RK; Ruiz, G; Ton, H; Wheeler, L; WoldeMussie, E, 2004)
"To determine, using anatomic measurements, whether daily oral dosing with memantine is both safe and effective to reduce the injury associated with experimental glaucoma in primates."7.72Efficacy and safety of memantine treatment for reduction of changes associated with experimental glaucoma in monkey, II: Structural measures. ( Feldmann, B; Hare, WA; Ruiz, G; Ton, H; Weinreb, RN; Wheeler, L; Wijono, M; WoldeMussie, E; Zangwill, L, 2004)
"Retinal ischemia increased vitreous concentrations of glutamate and glycine."7.70Memantine is neuroprotective in a rat model of pressure-induced retinal ischemia. ( Bach, M; Feuerstein, TJ; Knörle, R; Lagrèze, WA, 1998)
"To determine, using electrophysiological measures of visual system function, whether oral daily dosing of memantine is both safe and effective to reduce the injury associated with experimental glaucoma in primates."3.72Efficacy and safety of memantine treatment for reduction of changes associated with experimental glaucoma in monkey, I: Functional measures. ( Chun, T; Hare, WA; Lai, RK; Ruiz, G; Ton, H; Wheeler, L; WoldeMussie, E, 2004)
"To determine, using anatomic measurements, whether daily oral dosing with memantine is both safe and effective to reduce the injury associated with experimental glaucoma in primates."3.72Efficacy and safety of memantine treatment for reduction of changes associated with experimental glaucoma in monkey, II: Structural measures. ( Feldmann, B; Hare, WA; Ruiz, G; Ton, H; Weinreb, RN; Wheeler, L; Wijono, M; WoldeMussie, E; Zangwill, L, 2004)
"Retinal ischemia increased vitreous concentrations of glutamate and glycine."3.70Memantine is neuroprotective in a rat model of pressure-induced retinal ischemia. ( Bach, M; Feuerstein, TJ; Knörle, R; Lagrèze, WA, 1998)
"Treatment with memantine resulted in a significant reduction in RGC loss and NR1 expression in the eyes of rats COHT."1.34Expression of N-methyl-d-aspartate receptor 1 in rats with chronic ocular hypertension. ( Jung, SW; Kim, JH; Lee, NY; Park, CK, 2007)
"Chronic ocular hypertension was attained by laser photocoagulation of episcleral and limbal veins."1.31Neuroprotective effect of memantine in different retinal injury models in rats. ( Ruiz, G; Schwartz, M; Wheeler, LA; WoldeMussie, E; Yoles, E, 2002)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's4 (80.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
WoldeMussie, E3
Yoles, E1
Schwartz, M1
Ruiz, G3
Wheeler, LA1
Hare, WA2
Lai, RK1
Ton, H2
Chun, T1
Wheeler, L2
Weinreb, RN1
Wijono, M1
Feldmann, B1
Zangwill, L1
Kim, JH1
Lee, NY1
Jung, SW1
Park, CK1
Lagrèze, WA1
Knörle, R1
Bach, M1
Feuerstein, TJ1

Other Studies

5 other studies available for memantine and Ocular Hypertension

ArticleYear
Neuroprotective effect of memantine in different retinal injury models in rats.
    Journal of glaucoma, 2002, Volume: 11, Issue:6

    Topics: Action Potentials; Animals; Cell Count; Cell Survival; Chronic Disease; Electrophysiology; Excitator

2002
Efficacy and safety of memantine treatment for reduction of changes associated with experimental glaucoma in monkey, I: Functional measures.
    Investigative ophthalmology & visual science, 2004, Volume: 45, Issue:8

    Topics: Administration, Oral; Animals; Cell Count; Chronic Disease; Disease Models, Animal; Electroretinogra

2004
Efficacy and safety of memantine treatment for reduction of changes associated with experimental glaucoma in monkey, II: Structural measures.
    Investigative ophthalmology & visual science, 2004, Volume: 45, Issue:8

    Topics: Administration, Oral; Animals; Cell Count; Cell Survival; Disease Models, Animal; Excitatory Amino A

2004
Expression of N-methyl-d-aspartate receptor 1 in rats with chronic ocular hypertension.
    Neuroscience, 2007, Nov-23, Volume: 149, Issue:4

    Topics: Analysis of Variance; Animals; Cell Death; Disease Models, Animal; Excitatory Amino Acid Antagonists

2007
Memantine is neuroprotective in a rat model of pressure-induced retinal ischemia.
    Investigative ophthalmology & visual science, 1998, Volume: 39, Issue:6

    Topics: Animals; Cell Count; Chromatography, High Pressure Liquid; Disease Models, Animal; Excitatory Amino

1998