memantine has been researched along with Neuronal Ceroid-Lipofuscinoses in 2 studies
Neuronal Ceroid-Lipofuscinoses: A group of severe neurodegenerative diseases characterized by intracellular accumulation of autofluorescent wax-like lipid materials (CEROID; LIPOFUSCIN) in neurons. There are several subtypes based on mutations of the various genes, time of disease onset, and severity of the neurological defects such as progressive DEMENTIA; SEIZURES; and visual failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Currently there is no treatment for juvenile Batten disease, a fatal childhood neurodegenerative disorder caused by mutations in the CLN3 gene." | 1.38 | Age-dependent therapeutic effect of memantine in a mouse model of juvenile Batten disease. ( Cooper, JD; Kovács, AD; Pearce, DA; Ramji, S; Saje, A; Wong, A, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Finn, R | 1 |
| Kovács, AD | 2 |
| Pearce, DA | 2 |
| Saje, A | 1 |
| Wong, A | 1 |
| Ramji, S | 1 |
| Cooper, JD | 1 |
2 other studies available for memantine and Neuronal Ceroid-Lipofuscinoses
| Article | Year |
|---|---|
Treatment of the Ppt1(-/-) mouse model of infantile neuronal ceroid lipofuscinosis with the N-methyl-D-aspartate (NMDA) receptor antagonist memantine.
Topics: Animals; Disease Models, Animal; Disease Progression; Excitatory Amino Acid Antagonists; Memantine; | 2013 |
Age-dependent therapeutic effect of memantine in a mouse model of juvenile Batten disease.
Topics: Aging; Animals; Cerebral Cortex; Disease Models, Animal; Disease Progression; Dose-Response Relation | 2012 |