memantine has been researched along with Infarction, Middle Cerebral Artery in 8 studies
Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Memantine prevented cerebral ischemia-induced brain infarct and neuronal injury, and reduced oxygen-glucose deprivation-induced cortical neuronal apoptosis." | 7.83 | Memantine mediates neuroprotection via regulating neurovascular unit in a mouse model of focal cerebral ischemia. ( Chen, ZZ; Ji, J; Sun, XL; Yan, H; Yang, DD; Zhao, Z, 2016) |
| "Memantine prevented cerebral ischemia-induced brain infarct and neuronal injury, and reduced oxygen-glucose deprivation-induced cortical neuronal apoptosis." | 3.83 | Memantine mediates neuroprotection via regulating neurovascular unit in a mouse model of focal cerebral ischemia. ( Chen, ZZ; Ji, J; Sun, XL; Yan, H; Yang, DD; Zhao, Z, 2016) |
| " These results imply that the combination of MEM and HBO therapy not only prolongs the therapeutic window of HBO treatment, but also lowers the dosage requirement of MEM." | 1.42 | Combination of HBO and Memantine in Focal Cerebral Ischemia: Is There a Synergistic Effect? ( Huang, Y; Kinden, R; Lei, C; Liang, W; Qu, Y; Sang, H; Wang, F; Xie, Y; Xiong, L, 2015) |
| "Treatment with memantine or E2 significantly reduced infarct volume by >40% and significantly improved neurological function while treatment with TMP had no effect." | 1.40 | The neuroprotective effect of 17β-estradiol is independent of its antioxidative properties. ( Gröger, M; Plesnila, N, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (87.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Stanton, JA | 1 |
| Williams, EI | 1 |
| Betterton, RD | 1 |
| Davis, TP | 1 |
| Ronaldson, PT | 1 |
| Gröger, M | 1 |
| Plesnila, N | 1 |
| Wang, F | 1 |
| Liang, W | 1 |
| Lei, C | 1 |
| Kinden, R | 1 |
| Sang, H | 1 |
| Xie, Y | 1 |
| Huang, Y | 1 |
| Qu, Y | 1 |
| Xiong, L | 1 |
| Chen, ZZ | 1 |
| Yang, DD | 1 |
| Zhao, Z | 1 |
| Yan, H | 1 |
| Ji, J | 1 |
| Sun, XL | 1 |
| Wang, YC | 1 |
| Sanchez-Mendoza, EH | 1 |
| Doeppner, TR | 1 |
| Hermann, DM | 1 |
| Shih, AY | 1 |
| Blinder, P | 1 |
| Tsai, PS | 1 |
| Friedman, B | 1 |
| Stanley, G | 1 |
| Lyden, PD | 1 |
| Kleinfeld, D | 1 |
| Cho, GS | 1 |
| Lee, JC | 1 |
| Ju, C | 1 |
| Kim, C | 1 |
| Kim, WK | 1 |
| Kilic, U | 1 |
| Yilmaz, B | 1 |
| Reiter, RJ | 1 |
| Yüksel, A | 1 |
| Kilic, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pilot Study of Memantine for Enhanced Stroke Recovery[NCT02144584] | Early Phase 1 | 20 participants (Anticipated) | Interventional | 2014-01-31 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 other studies available for memantine and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Targeting organic cation transporters at the blood-brain barrier to treat ischemic stroke in rats.
Topics: Animals; Blood-Brain Barrier; Cations; Cimetidine; Infarction, Middle Cerebral Artery; Ischemic Stro | 2022 |
The neuroprotective effect of 17β-estradiol is independent of its antioxidative properties.
Topics: Animals; Antioxidants; Body Weight; Brain; Brain Infarction; Cresols; Disease Models, Animal; Dose-R | 2014 |
Combination of HBO and Memantine in Focal Cerebral Ischemia: Is There a Synergistic Effect?
Topics: Animals; Biomarkers; Blood-Brain Barrier; Catalase; Combined Modality Therapy; Dose-Response Relatio | 2015 |
Memantine mediates neuroprotection via regulating neurovascular unit in a mouse model of focal cerebral ischemia.
Topics: Animals; Brain Ischemia; Cerebral Veins; Collagen Type IV; Disks Large Homolog 4 Protein; Glucose; G | 2016 |
Post-acute delivery of memantine promotes post-ischemic neurological recovery, peri-infarct tissue remodeling, and contralesional brain plasticity.
Topics: Animals; Brain Infarction; Brain Ischemia; Infarction, Middle Cerebral Artery; Memantine; Mice; Mice | 2017 |
The smallest stroke: occlusion of one penetrating vessel leads to infarction and a cognitive deficit.
Topics: Animals; Brain Infarction; Brain Mapping; Calcium; Cognition Disorders; Disease Models, Animal; Dizo | 2013 |
N-Methyl-D-aspartate receptor antagonists memantine and MK-801 attenuate the cerebral infarct accelerated by intracorpus callosum injection of lipopolysaccharides.
Topics: Animals; Anti-Inflammatory Agents; Cerebral Infarction; Corpus Callosum; Dizocilpine Maleate; Drug S | 2013 |
Effects of memantine and melatonin on signal transduction pathways vascular leakage and brain injury after focal cerebral ischemia in mice.
Topics: Analysis of Variance; Animals; Cerebral Cortex; Cerebral Infarction; Corpus Striatum; Disease Models | 2013 |