memantine has been researched along with Friedreich Ataxia in 1 studies
Friedreich Ataxia: An autosomal recessive disease, usually of childhood onset, characterized pathologically by degeneration of the spinocerebellar tracts, posterior columns, and to a lesser extent the corticospinal tracts. Clinical manifestations include GAIT ATAXIA, pes cavus, speech impairment, lateral curvature of spine, rhythmic head tremor, kyphoscoliosis, congestive heart failure (secondary to a cardiomyopathy), and lower extremity weakness. Most forms of this condition are associated with a mutation in a gene on chromosome 9, at band q13, which codes for the mitochondrial protein frataxin. (From Adams et al., Principles of Neurology, 6th ed, p1081; N Engl J Med 1996 Oct 17;335(16):1169-75) The severity of Friedreich ataxia associated with expansion of GAA repeats in the first intron of the frataxin gene correlates with the number of trinucleotide repeats. (From Durr et al, N Engl J Med 1996 Oct 17;335(16):1169-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 24-year-old patient with Friedreich's ataxia presented with advanced visual loss due to optic nerve atrophy." | 1.43 | [Memantine for optic nerve atrophy in Friedreich's Ataxia]. ( Boesch, S; Manousaridis, K; Mennel, S; Peter, S, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Peter, S | 1 |
| Manousaridis, K | 1 |
| Boesch, S | 1 |
| Mennel, S | 1 |
1 other study available for memantine and Friedreich Ataxia
| Article | Year |
|---|---|
[Memantine for optic nerve atrophy in Friedreich's Ataxia].
Topics: Friedreich Ataxia; Humans; Male; Memantine; Optic Atrophy; Tomography, Optical Coherence; Treatment | 2016 |