Page last updated: 2024-10-30

memantine and Fibromyalgia

memantine has been researched along with Fibromyalgia in 6 studies

Fibromyalgia: A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95)

Research Excerpts

ExcerptRelevanceReference
"To evaluate the efficacy of memantine on metabolite levels in different areas of the brain and to determine whether changes in metabolite levels correlate with clinical variables in Fibromyalgia (FM) patients."9.19Changes in metabolites after treatment with memantine in fibromyalgia. A double-blind randomized controlled trial with magnetic resonance spectroscopy with a 6-month follow-up. ( Andrés, E; Fayed, N; Garcia-Campayo, J; Herrera-Mercadal, P; López del Hoyo, Y; Magallon, R; Olivan-Blázquez, B; Pérez-Yus, MC; Puebla-Guedea, M; Viguera, L, 2014)
"MEDLINE, EMBASE and CENTRAL databases were searched for comparative trials using memantine, either against placebo or active medications, for chronic pain in adults."9.01A systematic review and meta-analysis of memantine for the prevention or treatment of chronic pain. ( Kurian, R; Raza, K; Shanthanna, H, 2019)
"We have recently reported that memantine has a clinically relevant antimanic and long-lasting mood-stabilizing effect in treatment-resistant bipolar disorders, both as augmenting agent and as monotherapy."7.80Memantine in the treatment and prophylaxis of bipolar II disorder and comorbid fibromyalgia: a case report. ( DE Chiara, L; Kahn, DA; Koukopoulos, A; Koukopoulos, AE; Serra, G, 2014)
"Memantine was administered at doses of 20mg/d after 1 month of titration."6.79Efficacy of memantine in the treatment of fibromyalgia: A double-blind, randomised, controlled trial with 6-month follow-up. ( Andrés, E; Fayed, N; Garcia-Campayo, J; Herrera-Mercadal, P; López-Del-Hoyo, Y; Magallon, R; Olivan-Blázquez, B; Pérez-Yus, MC; Puebla-Guedea, M; Roca, M, 2014)
"Fibromyalgia is a prevalent chronic rheumatic disease of great clinical importance."6.78Evaluation of the efficacy of memantine in the treatment of fibromyalgia: study protocol for a doubled-blind randomized controlled trial with six-month follow-up. ( Andrés, E; Arcega, R; Garcia-Campayo, J; López-del-Hoyo, Y; Magallon, R; Masluk, B; Olivan-Blázquez, B; Pérez-Yus, MC; Puebla, M; Roca, M, 2013)
"To evaluate the efficacy of memantine on metabolite levels in different areas of the brain and to determine whether changes in metabolite levels correlate with clinical variables in Fibromyalgia (FM) patients."5.19Changes in metabolites after treatment with memantine in fibromyalgia. A double-blind randomized controlled trial with magnetic resonance spectroscopy with a 6-month follow-up. ( Andrés, E; Fayed, N; Garcia-Campayo, J; Herrera-Mercadal, P; López del Hoyo, Y; Magallon, R; Olivan-Blázquez, B; Pérez-Yus, MC; Puebla-Guedea, M; Viguera, L, 2014)
"MEDLINE, EMBASE and CENTRAL databases were searched for comparative trials using memantine, either against placebo or active medications, for chronic pain in adults."5.01A systematic review and meta-analysis of memantine for the prevention or treatment of chronic pain. ( Kurian, R; Raza, K; Shanthanna, H, 2019)
"We have recently reported that memantine has a clinically relevant antimanic and long-lasting mood-stabilizing effect in treatment-resistant bipolar disorders, both as augmenting agent and as monotherapy."3.80Memantine in the treatment and prophylaxis of bipolar II disorder and comorbid fibromyalgia: a case report. ( DE Chiara, L; Kahn, DA; Koukopoulos, A; Koukopoulos, AE; Serra, G, 2014)
"Memantine was administered at doses of 20mg/d after 1 month of titration."2.79Efficacy of memantine in the treatment of fibromyalgia: A double-blind, randomised, controlled trial with 6-month follow-up. ( Andrés, E; Fayed, N; Garcia-Campayo, J; Herrera-Mercadal, P; López-Del-Hoyo, Y; Magallon, R; Olivan-Blázquez, B; Pérez-Yus, MC; Puebla-Guedea, M; Roca, M, 2014)
"Fibromyalgia is a prevalent chronic rheumatic disease of great clinical importance."2.78Evaluation of the efficacy of memantine in the treatment of fibromyalgia: study protocol for a doubled-blind randomized controlled trial with six-month follow-up. ( Andrés, E; Arcega, R; Garcia-Campayo, J; López-del-Hoyo, Y; Magallon, R; Masluk, B; Olivan-Blázquez, B; Pérez-Yus, MC; Puebla, M; Roca, M, 2013)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kurian, R1
Raza, K1
Shanthanna, H1
Serra, G2
DE Chiara, L1
Koukopoulos, AE1
Koukopoulos, A1
Kahn, DA1
Olivan-Blázquez, B3
Herrera-Mercadal, P2
Puebla-Guedea, M2
Pérez-Yus, MC3
Andrés, E3
Fayed, N2
López-Del-Hoyo, Y2
Magallon, R3
Roca, M2
Garcia-Campayo, J3
López del Hoyo, Y1
Viguera, L1
Recla, JM1
Sarantopoulos, CD1
Puebla, M1
Masluk, B1
Arcega, R1

Reviews

1 review available for memantine and Fibromyalgia

ArticleYear
A systematic review and meta-analysis of memantine for the prevention or treatment of chronic pain.
    European journal of pain (London, England), 2019, Volume: 23, Issue:7

    Topics: Adult; Analgesics; Chronic Pain; Fibromyalgia; Humans; Memantine; Receptors, N-Methyl-D-Aspartate

2019

Trials

3 trials available for memantine and Fibromyalgia

ArticleYear
Efficacy of memantine in the treatment of fibromyalgia: A double-blind, randomised, controlled trial with 6-month follow-up.
    Pain, 2014, Volume: 155, Issue:12

    Topics: Adult; Cognition Disorders; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Fibromya

2014
Changes in metabolites after treatment with memantine in fibromyalgia. A double-blind randomized controlled trial with magnetic resonance spectroscopy with a 6-month follow-up.
    CNS neuroscience & therapeutics, 2014, Volume: 20, Issue:11

    Topics: Adult; Aspartic Acid; Brain; Creatine; Dopamine Agents; Double-Blind Method; Female; Fibromyalgia; F

2014
Evaluation of the efficacy of memantine in the treatment of fibromyalgia: study protocol for a doubled-blind randomized controlled trial with six-month follow-up.
    Trials, 2013, Jan-03, Volume: 14

    Topics: Brain; Clinical Protocols; Cognition; Double-Blind Method; Drug Administration Schedule; Excitatory

2013

Other Studies

2 other studies available for memantine and Fibromyalgia

ArticleYear
Memantine in the treatment and prophylaxis of bipolar II disorder and comorbid fibromyalgia: a case report.
    Journal of psychiatric practice, 2014, Volume: 20, Issue:3

    Topics: Bipolar Disorder; Diagnostic and Statistical Manual of Mental Disorders; Dopamine Agents; Female; Fi

2014
Combined use of pregabalin and memantine in fibromyalgia syndrome treatment: a novel analgesic and neuroprotective strategy?
    Medical hypotheses, 2009, Volume: 73, Issue:2

    Topics: Analgesics; Chronic Disease; Drug Therapy, Combination; Fibromyalgia; gamma-Aminobutyric Acid; Human

2009