Page last updated: 2024-10-30

memantine and Dyskinesia, Drug-Induced

memantine has been researched along with Dyskinesia, Drug-Induced in 7 studies

Dyskinesia, Drug-Induced: Abnormal movements, including HYPERKINESIS; HYPOKINESIA; TREMOR; and DYSTONIA, associated with the use of certain medications or drugs. Muscles of the face, trunk, neck, and extremities are most commonly affected. Tardive dyskinesia refers to abnormal hyperkinetic movements of the muscles of the face, tongue, and neck associated with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS). (Adams et al., Principles of Neurology, 6th ed, p1199)

Research Excerpts

ExcerptRelevanceReference
"Memantine was well tolerated, without any serious adverse events, or worsening in the parkinsonian motor score."2.82Memantine and reduced time with dyskinesia in Parkinson's Disease. ( Wictorin, K; Widner, H, 2016)
"Memantine treatment was associated with lower axial motor symptom and dyskinesia scores but did not improve gait."2.78Memantine for axial signs in Parkinson's disease: a randomised, double-blind, placebo-controlled pilot study. ( Allorge, D; Blum, D; Bordet, R; Defebvre, L; Delval, A; Destée, A; Devos, D; Duhamel, A; Dujardin, K; Hossein-Foucher, C; Moreau, C; Petyt, G; Sablonnière, B; Schraen, S; Tiffreau, V, 2013)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wictorin, K1
Widner, H1
Varanese, S1
Howard, J1
Di Rocco, A1
Moreau, C1
Delval, A1
Tiffreau, V1
Defebvre, L1
Dujardin, K1
Duhamel, A1
Petyt, G1
Hossein-Foucher, C1
Blum, D1
Sablonnière, B1
Schraen, S1
Allorge, D1
Destée, A1
Bordet, R1
Devos, D1
Vidal, EI1
Fukushima, FB1
Valle, AP1
Villas Boas, PJ1
Andreassen, OA1
Waage, J1
Finsen, B1
Jørgensen, HA1
Wesemann, W1
Sontag, KH1
Maj, J1
Hanağasi, HA1
Kaptanoglu, G1
Sahin, HA1
Emre, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study of Memantine to Treat Gait Disorders And Attention Deficit In Parkinson's Disease: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Monocentric Trial[NCT01108029]Phase 428 participants (Actual)Interventional2009-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for memantine and Dyskinesia, Drug-Induced

ArticleYear
[Pharmacodynamics and pharmacokinetics of memantine].
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:8

    Topics: Amantadine; Animals; Antidepressive Agents; Body Temperature; Catalepsy; Dopamine; Dyskinesia, Drug-

1983

Trials

2 trials available for memantine and Dyskinesia, Drug-Induced

ArticleYear
Memantine and reduced time with dyskinesia in Parkinson's Disease.
    Acta neurologica Scandinavica, 2016, Volume: 133, Issue:5

    Topics: Aged; Antiparkinson Agents; Cross-Over Studies; Double-Blind Method; Dyskinesia, Drug-Induced; Excit

2016
Memantine for axial signs in Parkinson's disease: a randomised, double-blind, placebo-controlled pilot study.
    Journal of neurology, neurosurgery, and psychiatry, 2013, Volume: 84, Issue:5

    Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Disability Evaluation; Double-Blind Method; Dyskinesi

2013

Other Studies

4 other studies available for memantine and Dyskinesia, Drug-Induced

ArticleYear
NMDA antagonist memantine improves levodopa-induced dyskinesias and "on-off" phenomena in Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2010, Mar-15, Volume: 25, Issue:4

    Topics: Aged; Antiparkinson Agents; Dopamine Agents; Dyskinesia, Drug-Induced; Female; Humans; Incidence; Le

2010
Unexpected improvement in levodopa-induced dyskinesia and on-off phenomena after introduction of memantine for treatment of Parkinson's disease dementia.
    Journal of the American Geriatrics Society, 2013, Volume: 61, Issue:1

    Topics: Aged, 80 and over; Antiparkinson Agents; Dementia; Dopamine Agents; Dyskinesia, Drug-Induced; Humans

2013
Memantine attenuates the increase in striatal preproenkephalin mRNA expression and development of haloperidol-induced persistent oral dyskinesias in rats.
    Brain research, 2003, Dec-24, Volume: 994, Issue:2

    Topics: Analysis of Variance; Animals; Behavior, Animal; Cell Count; Corpus Striatum; Dopamine Antagonists;

2003
The use of NMDA antagonist memantine in drug-resistant dyskinesias resulting from L-dopa.
    Movement disorders : official journal of the Movement Disorder Society, 2000, Volume: 15, Issue:5

    Topics: Adult; Antiparkinson Agents; Dopamine Agents; Dose-Response Relationship, Drug; Drug Therapy, Combin

2000