memantine has been researched along with Disease Models, Animal in 241 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 10 (4.15) | 18.2507 |
2000's | 59 (24.48) | 29.6817 |
2010's | 132 (54.77) | 24.3611 |
2020's | 40 (16.60) | 2.80 |
Authors | Studies |
---|---|
Igarashi, K; Kashiwagi, K; Marchetti, C; Milelli, A; Minarini, A; Saiki, R; Toida, T; Tumiatti, V; Yoshizawa, Y | 1 |
Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ | 1 |
Bai, R; Gu, J; Guo, J; Jiang, X; Lv, Y; Mi, Z; Shi, Y; Xie, Y; Yao, C; Zhang, C; Zhou, T | 1 |
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
Brea, JM; Companys-Alemany, J; Griñán-Ferré, C; Johnson, JW; Kurnikova, MG; Loza, MI; Pallàs, M; Patel, DS; Pérez, B; Phillips, MB; Soto, D; Sureda, FX; Turcu, AL; Vázquez, S | 1 |
Bian, Z; Song, Z; Wang, X; Zhang, Z; Zhu, A; Zhu, G | 1 |
Chen, J; Chen, T; Fan, W; Li, Z; Lin, D; Liu, S; Liu, Z | 1 |
Annweiler, C; Bartha, R; Beauchet, O; Bellyou, M; Broberg, DN; Montero-Odasso, M; Wong, D | 1 |
Blezer, ELA; Buitelaar, JK; Dijkhuizen, RM; Glennon, JC; Otte, WM; Smeele, CE; Straathof, M; van der Toorn, A; van Heijningen, C | 1 |
Fukunaga, K; Inagaki, R; Moriguchi, S; Saido, TC; Saito, T | 1 |
Andrzejewski, K; Conde, SV; Jampolska, M; Kaczyńska, K; Mojzych, I | 1 |
Campos, Á; Heredia, M; Mollá, B; Sanz, P | 1 |
Companys-Alemany, J; Griñán-Ferré, C; Pallàs, M; Turcu, AL; Vázquez, S | 1 |
Albayrak, G; Bağrıaçık, EÜ; Bali, EB; Korkmaz, FD | 2 |
Aboul-Fotouh, S; El-Salam, MFA; Elayat, WM; Elhossiny, RM; Habib, MZ; Hassan, GAM; Mohamad, MI; Zohny, SM | 1 |
Anoush, M; Bijani, S; Hosseini, MJ; Jahanpour, F; Kalantari-Hesari, A; Moslemifar, F | 1 |
Akçay, E; Çakir, Z; Gevrek, F; Özsoy, Ş | 1 |
Beniashvili, A; Jürgenson, M; Morozova, M; Noortoots, A; Zapolski, M; Zharkovskaja, T; Zharkovsky, A | 1 |
Borah, A; Dutta, A; Gothwal, A; Gupta, U; Kumar, H; Nakhate, KT | 1 |
Abdel Ghaffar, AM; Ali, HE; Radwan, RR | 1 |
Fu, S; Shen, YE; Wang, QJ; Wang, RT; Wang, X; Zhang, X; Zhang, YN | 1 |
Bures, J; Dolezal, R; Douda, L; Douda, T; Herman, D; Karasova, JZ; Kopacova, M; Kvetina, J; Peterova, E; Radochova, V; Rejchrt, S; Sestak, V; Tacheci, I | 1 |
Gzielo, K; Krawczyk, M; Nikiforuk, A; Popik, P; Potasiewicz, A | 1 |
Abbasnezhad, A; Abd El-Ghafar, OA; Abhilash, L; Abouzid, KAM; Achberger, AM; Ackerman, S; Akhatayeva, Z; Akin, D; Al-Kaysi, RO; Alakhdar, AA; Alame, M; Aleksic Sabo, V; Alinezhadbalalami, N; Allen, JD; Alonso, JM; Alqatani, S; Alsayed, B; Álvarez Larraondo, M; Alvarez, M; Amini, SB; An, Z; Anasir, MI; Anderson, GH; Andremont, A; Andrés, S; Angel, S; Anigboro, AA; Anini, Y; Antonides, CFJ; Arafa, K; Arafa, RK; Aryal, UK; Asbaghi, O; Assefa, MK; Atyah, M; Avwioroko, OJ; Ayora-Talavera, G; Azpilikueta, A; Azyazov, VN; Ba, YF; Bachmann, KF; Badoual, J; Bae, SJ; Baek, SH; Bahrami, B; Bai, J; Baid-Agrawal, S; Bailey, MR; Baillie, JK; Balani, N; Balcar, VJ; Banica, T; Banks, L; Barb, J; Bardeen, CJ; Barrett, HE; Bartnikowski, N; Bashir, R; Battaglia, M; Bautista-Hernández, V; Becker, B; Beekman, FJ; Benidir, M; Benjelloun, M; Bentley, RF; Bergé, J; Berger, D; Bernsen, MR; Berraondo, P; Bhattacharya, R; Bhayani, SB; Bi, W; Bi, X; Bi, YL; Bi, Z; Bian, K; Biesecker, LG; Billadeau, DD; Blaszczyk, R; Blum, JL; Boachie, R; Boelte, K; Bogers, AJJC; Boileau, I; Bonduelle, C; Bonny, O; Bonsu, JM; Boos, LA; Borges-Argáez, R; Bouchard, PA; Boudot, C; Bourgeade-Delmas, S; Boutet-Robinet, E; Boyle, AJ; Branigan, D; Briones, S; Broniowska, KA; Brossas, JY; Brown, WA; Brzezinska, J; Buitron, G; Burnier, M; Bursulaya, B; Burton, PR; Bush, AA; Busuttil, RW; Cabello-Aguilar, S; Cáceres-Farfán, M; Cacheux, V; Caffrey, PJ; Cai, B; Cai, Q; Cai, S; Cai, Y; Calders, P; Cammarota, G; Campbell, DA; Cancelli, C; Cao, Q; Cao, WH; Cao, X; Capet, M; Capoluongo, E; Carey, ME; Carnero, M; Carrasco, LI; Carreno, J; Carrillo-Reyes, J; Casini, I; Cassar, M; Catalan, G; Cattamanchi, A; Cazares-Granillo, M; Celie, B; Cen, YK; Cena, H; Cerbo, RM; Ceron, E; Cetina-Montejo, L; Chaâbane-Banaoues, R; Chabanet, C; Chace-Donahue, F; Chalfun-Júnior, A; Chan-Balan, R; Chang, CS; Chen, CS; Chen, D; Chen, J; Chen, L; Chen, PN; Chen, Q; Chen, S; Chen, W; Chen, WP; Chen, X; Chen, Z; Cheng, H; Cheng, J; Cheng, Q; Cheng, T; Chi, T; Chianelli, D; Chieppa, M; Child, CJ; Cho, JH; Cho, JY; Chogtu, B; Choi, GH; Choi, J; Choi, M; Choi, NG; Cholu, CO; Chow, ES; Chowdhury, AH; Chu, PC; Chu, Q; Chu, S; Chua, H; Chung, T; Chunyan, L; Church, JS; Civardi, E; Cobiella, J; Colinge, J; Collado, CJ; Collins, TJ; Cong, LM; Conkrite, KL; Cope, SJ; Corbett, JA; Cornet, M; Cornillot, E; Corvaisier, S; Costes-Martineau, V; Courtioux, B; Coussens, M; Covino, M; Criado, A; Cui, J; Cui, Y; Cunitz, BW; Curry, AE; Cussó, L; D'Urzo, AD; D'Urzo, KA; Dabbous, S; Dahlgren, RA; Dai, H; Dai, T; Dai, W; Dalinghaus, M; Dang, S; Davalos, RV; Davidson, H; de Andrea, CE; De Angelis, M; de Blois, E; de Carvalho, PA; De Clercq, E; De Giuseppe, R; de Jong, M; De Langhe, S; De Oliveira, L; de Souza Pinto Lemgruber, R; de Souza, LB; de Swart, J; De Wandele, I; de Woestijne, PCV; Delaney, S; Delorme, M; Delvenne, P; Deng, L; Deng, Z; Denkinger, CM; der Meulen, MHV; Deraeve, C; Desco, M; DeSilva, S; Destere, A; Dhali, A; Di Ciano, P; Dias-Santagata, D; Diskin, SJ; Djè, MK; Doddipatla, S; Doerr, AJ; Dokla, EME; Domiciano, D; Domingo, N; Dong, C; Dong, J; Dong, Q; Dong, S; Dong, X; Dong, Z; Douair, I; Douglas, TA; Doyle, SM; Drain, PK; Du, K; Du, L; Du, Q; Du, S; Duan, C; Duan, H; Duan, J; Duan, S; Duan, W; Dueluzeau, R; Dukic, L; Dunmire, BL; Duvauchelle, T; Dymek, B; Dzwonek, K; Earnest, A; Eckardt, KU; El Ghadraoui, L; El Massoudi, S; Elloumi, F; Elnour, IE; Embarak, S; Ende, M; England, K; Enikeev, D; Enyedy, I; Epple, R; Erickson, GE; Eriksson, J; Erndt-Marino, J; Errachidi, F; Etxeberria, I; Evan, AP; Fairlamb, AH; Falahi, E; Fan, CC; Fan, H; Fan, M; Fan, MZ; Fan, S; Fan, Y; Fang, CS; Fang, J; Fang, X; Fang, Z; Farmany, A; Farooqi, A; Farouk, HO; Fazelipour, S; Feng, D; Feng, J; Feng, JX; Feng, YL; Ferraz, SL; Ferreira, CR; Figenshau, RS; Finn, AV; Fiseha, T; Fleischer, AS; Fogleman, AD; Fontaine, O; Ford, CR; Fouladvand, F; Four, M; Fousteri, G; Francis, JR; Fraser, JF; Frazier, RP; Fu, H; Fu, P; Fu, YJ; Fujishima, A; Fuster, V; Gabilan, JC; Gagliani, N; Gai, QY; Galán-Arriola, C; Gale, P; Galimova, GR; Galkin, A; Gallo, A; Gallo, AA; Gang, DD; Ganschow, S; Gao, C; Gao, F; Gao, GP; Gao, H; Gao, K; Gao, M; Gao, MY; Gao, P; Gao, R; Gao, S; Gao, WJ; Gao, Y; Garbacz, P; García Ruiz, L; Garcia, EM; Garofoli, F; Gasbarrini, A; Gattinoni, L; Gaudig, M; Gbureck, U; Ge, X; Genko, N; Gentile, GL; George, MW; Gerety, GF; Gestwicki, JE; Geusens, PP; Ghassemi, M; Giardina, JD; Giebultowicz, JM; Gifford, CA; Gijsen, FJH; Gilfillan, R; Gilson, E; Gingl, K; Giuliano, C; Glybochko, P; Goessler, W; Gofflot, S; Golab, J; Goldstein, A; Golebiowski, A; Gómez, L; Gómez-Carballo, J; Gonçalves, PEO; Gonzales, R; Gonzalez-Cotto, M; González-Fernández, D; Gonzalez-Lopez de Turiso, F; Goodman, JM; Govinda Raju, S; Grimm, J; Gross, AJ; Gruenheid, S; Gu, C; Gu, FF; Gu, S; Gu, Z; Guest, RL; Gui, C; Gui, J; Guillem, A; Guo, G; Guo, L; Guo, Q; Guo, S; Guo, SW; Guo, W; Guo, Y; Guo, YG; Guo, Z; Guretzky, JA; Haenggi, M; Hahn, MS; Hakkola, J; Halim, AA; Hampel, D; Han, B; Han, BH; Han, D; Han, G; Han, J; Han, LZ; Han, R; Han, S; Han, X; Han, Z; Handley, MA; Hanke, I; Hannongbua, S; Hao, P; Happ, JT; Hara, M; Haraux, F; Hare, JL; Harper, JD; Hartley, AM; Harvey, E; Hashimoto, K; Hassan, HM; Hautajärvi, H; Hayton, TW; He, C; He, H; He, HJ; He, WP; He, Y; He, Z; Hedrick, V; Heffernan, JK; Hegrová, J; Heidarimoghadam, R; Helms, K; Hengphasatporn, K; Henry, D; Herrmann, TRW; Hesson, T; Himmelbauer, MK; Hindle, A; Hoffmann, R; Hogg, N; Hong, KB; Hong, SK; Honjol, Y; Hood, C; Hsi, RS; Hsu, JL; Hu, B; Hu, BC; Hu, D; Hu, H; Hu, J; Hu, K; Hu, M; Hu, MK; Hu, T; Hu, W; Hu, Y; Hu, Z; Hua, S; Huang, H; Huang, J; Huang, L; Huang, M; Huang, P; Huang, X; Huang, Y; Huang, Z; Hukkanen, J; Hung, MC; Huo, X; Hyötyläinen, T; Ianiro, G; Ibanez, B; Imran, M; Ireland, S; Irwin, MS; Ishiguro, H; Jackowski, K; Jackson, C; Jacob, SI; Jahromy, MH; Jakob, SM; Jang, J; Javvaji, PK; Jefferson, KK; Jena, P; Ji, H; Jiang, F; Jiang, GH; Jiang, H; Jiang, J; Jiang, X; Jiang, Z; Jiao, J; Jiménez, A; Jin, X; Jincai, W; Jintao, X; Jo, K; Jofra, T; Johari, Y; Johnson, ACM; Jones, JH; Josephine Fauci, A; Juhl, AK; Jun, S; Kaiser, RI; Kajioka, J; Kajiyama, H; Kalliyil, A; Kalthur, SG; Kamalanathan, M; Kamaldinov, T; Kanaani, L; Kang, D; Kang, J; Kang, S; Känsäkoski, P; Kaplan, DL; Karwan, M; Kasibhatla, S; Kaur, A; Kawazoe, Y; Ke, C; Keyser, J; Khalique, A; Khan, IT; Kharshoum, RM; Kher, R; Kherani, J; Ki, KK; Kikkawa, F; Kikkawa, R; Kim, BT; Kim, EH; Kim, GA; Kim, GD; Kim, HB; Kim, HG; Kim, JS; Kim, MJ; Kim, SI; Kim, SJ; Kim, Y; King, K; Kinyamu-Akunda, J; Kirkkala, T; Kjaer-Sorensen, K; Kleppinger, EL; Kloner, RA; Klopfenstein, TJ; Knappe, D; Knezevic, P; Kobos, LM; Kohli, M; Kolano, L; Kolodgie, FD; Kolte, AP; Koneru, B; Kong, D; Kong, F; Kong, X; Konggidinata, MI; Köpke, M; Koski, KG; Kotsis, F; Köttgen, A; Kouakou-Kouamé, CA; Kraemer, US; Krane, V; Krehbiel, CR; Krenning, BJ; Kretzschmar, D; Ku, KB; Kubota, Y; Kulich, P; Kumar, NG; Kupiec-Weglinski, JW; Lalani, SS; Lan, X; Landfeldt, E; Langenberg, E; Lapauw, B; Larkin, J; Lassoued, MA; Laukhtina, E; Laura Martinez, J; Laveillé, A; Lavela, P; Law, AD; Lazraq, A; Le Foll, B; Lee, BK; Lee, C; Lee, CS; Lee, EJ; Lee, EY; Lee, G; Lee, HY; Lee, JH; Lee, JJ; Lee, JO; Lee, JS; Lee, R; Lei, H; Lei, P; Lellouche, F; Lennerz, JK; Leong, W; Leslie, I; Lessem, E; Levin, M; Levinger, I; Li, C; Li, CW; Li, CX; Li, CY; Li, D; Li, H; Li, HM; Li, J; Li, L; Li, LM; Li, N; Li, S; Li, W; Li, X; Li, XX; Li, Y; Li, Z; Li, ZL; Li, ZX; Lian, Q; Liang, C; Liang, GH; Liang, H; Liang, J; Liang, X; Liao, CX; Liao, R; Ličbinský, R; Lim, YS; Lima, HK; Lin, JG; Lin, L; Lin, S; Lin, WP; Lin, Z; Liso, M; Liu, BX; Liu, C; Liu, H; Liu, J; Liu, M; Liu, Q; Liu, S; Liu, SF; Liu, SL; Liu, T; Liu, W; Liu, X; Liu, XB; Liu, Y; Liu, YY; Liu, Z; Liu, ZQ; Lobo, M; Loitzenbauer, M; López, F; Lopez, G; López, GJ; Lou, Z; Lu, IC; Lu, J; Lu, M; Lu, W; Lu, X; Lu, Y; Luhovyy, BL; Luna-Abanto, J; Luo, J; Luo, K; Luo, L; Luo, M; Luo, W; Luo, X; Luo, XM; Lv, Y; Lv, YQ; Lyu, HD; Lyu, J; Ma, C; Ma, G; Ma, L; Ma, Q; Ma, X; Ma, Y; Macha, SJ; MacLean, E; Mahalapbutr, P; Maina, T; Malfait, F; Malfertheiner, MV; Malzert-Fréon, A; Mansouri, E; Mao, C; Marcellin, E; Marchiori, PER; Marcotte, DJ; Maréchal, A; Maric, N; Maris, JM; Maron, L; Marti, CN; Martínez-Milla, J; Mateo, J; Mather, K; Mathison, CJN; Matthay, MA; Maxwell, CL; Mazier, D; Mazumder, D; Mazurkiewicz, M; Mazzucchelli, TG; McAuley, DF; Mccoy, K; McVicar, DW; Mebel, AM; Mech, A; Meester, EJ; Meiselbach, H; Melero, I; Ménard, G; Meng, X; Mengya, Y; Merle, G; Meunier, B; Mfarrej, B; Mi, K; Migueliz, I; Mikuška, P; Miladi, K; Miletich, R; Millar, JE; Mills, MR; Milne, R; Minute, L; Misiak, M; Mo, F; Modi, A; Mok, F; Molina, C; Mollen, CJ; Molteni, V; Montalto, M; Montet, D; Monti, MC; Moor, MB; Moravec, P; Morsiani, C; Murillo, E; Murugan, P; Muslem, R; Myers, RK; N'guessan, FK; Nabil, H; Nadal, J; Nadeem, M; Nafady, MM; Nafie, MS; Nair, HP; Nakano, R; Nance, J; Naren, N; Neil, CJ; Nelson, J; Nery, FC; Netsch, C; Nguyen, TH; Ni, L; Ni, YX; Nie, W; Nielsen, LK; Nigam, K; Nikolayev, AA; Nishiyama, M; Niu, LL; Niu, PP; Nock, BA; Noer, PR; Noll, G; Noll, S; Norenberg, JP; Nowicka, J; Nutho, B; O'Connor, M; Obonyo, NG; Ochiai, T; Ochoa, MC; Oh, BL; Oh, S; Olczak, J; Olivares, X; Ommurugan, B; Oosthuizen, MC; Operario, D; Orešič, M; Oshima, K; Otano, I; Ou, Y; Owen, TW; Oxvig, C; Pacey, V; Pai, M; Paik, H; Paiva, R; Palmieri, EM; Palpant, N; Pan, L; Pan, Q; Panahi, S; Pang, B; Pang, ZC; Pannecouque, C; Paris, L; Park, D; Park, DJ; Park, E; Park, EC; Park, IH; Park, JH; Park, JI; Park, S; Passmore, MR; Pattaranggoon, NC; Paun, M; Pedersen, S; Pedron, J; Peng, M; Peng, X; Penzhorn, BL; Pérez-Camargo, D; Perez-Maldonado, R; Pérez-Vicente, C; Pham, TD; Pickering, L; Pickersgill, NA; Pinault, E; Pinotsis, N; Plan, M; Pocino, K; Poh, CL; Pons, EDC; Popoff, MR; Porri, D; Pourmand, A; Pratviel, G; Prudente, DO; Qi, H; Qi, N; Qian, LY; Qiao, L; Qiao, Q; Qin, QP; Qiu, N; Qiu, SW; Qu, F; Quan, M; Quigg, A; Raee, E; Raibaud, P; Ramanitrahasimbola, D; Rapoport, L; Rasby, RJ; Rasoanirina, BNV; Raspini, B; Ratner, JR; Razafindrakoto, Z; Redd, MA; Ren, H; Ren, N; Rey, J; Reynolds, CP; Rich, PR; Richards, CJ; Rigol, M; Rimoldi, S; Robert, P; Rodrigues, AE; Roe, JH; Rohde, S; Rokita, JL; Roland, J; Rombaut, L; Ronkainen, J; Rothenberg, SM; Roy, SC; Ruan, Z; Rucker, PV; Rueda, D; Ruhwald, M; Rungrotmongkol, T; Rupert, AS; Rusjan, P; Ryabov, AD; Rysä, J; Saad, NES; Sabioni, P; Sadow, PM; Sahai, N; Salem, HF; Salinas, B; Salonurmi, T; Samé Guerra, D; Sánchez, J; Sanchez-González, J; Sanmamed, MF; Sansores-Peraza, P; Santoro, JC; Santschi, PH; Saritas, T; Sarkisova, Y; Savolainen, MJ; Scherberich, JE; Schlom, DG; Schmelz, EM; Schmid, MC; Schneider, MP; Schumacher, S; Schwartz, JC; Schwartzer, JJ; Schwehr, K; Schweitzer, DH; Scott, ME; Sedky, NK; See Hoe, L; Sejian, V; Selvaraju, S; Sen, SK; Seo, G; Šerý, O; Settles, JA; Sfar, S; Shaffer, J; Shan, GL; Shang, Q; Shannahan, JH; Shao, B; Shao, H; Shao, J; Shao, ZH; Shasha, Y; Shaw, K; Sheeba, V; Shekar, K; Shen, G; Shen, H; Shen, XD; Shen, Y; Sherrell, PC; Shete, PB; Shi, AX; Shi, J; Shi, JH; Shi, S; Shi, X; Shigeta, Y; Shimbo, A; Shin, E; Sikka, N; Silhavy, TJ; Simanon, N; Simard, S; Simon, J; Simon, M; Simpson, SD; Simundic, AM; Since, M; Singh, B; Singhroy, DN; Sinisterra, OT; Smith, EH; Sobreira, TJP; Solanes, N; Somasundar, Y; Sommerer, C; Sonei, A; Song, B; Song, E; Song, J; Song, M; Song, Y; Soo Lee, M; Sorensen, MD; Sournia-Saquet, A; Spaepen, E; Spirk, D; Srivastava, S; Stancill, JS; Stanczak, PS; Starenki, D; Starr, F; Step, DL; Steubl, D; Stigliani, JL; Stráská, J; Sträter, N; Su, ZZ; Sudano, I; Suen, JY; Suh, HJ; Sui, ZY; Suico, JG; Suleiman, K; Sumon, K; Sun, HB; Sun, J; Sun, L; Sun, LL; Sun, M; Sun, Q; Sun, W; Sun, X; Sun, XF; Sun, Y; Sun, YB; Sun, YH; Sun, YN; Sun, Z; Sunada, K; Suzuki, S; Sylvan, JB; Takala, J; Talla, D; Tamir, Z; Tan, SJ; Tanda, S; Tang, H; Tang, J; Tang, LF; Tang, SJ; Tang, Y; Tao, FB; Tappel, R; 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Eisenberg, E; Pud, D | 1 |
Abramowski, D; De Deyn, PP; Staufenbiel, M; Van Dam, D | 1 |
Higuchi, M; Iwata, N; Matsuba, Y; Saido, TC; Sasamoto, K; Sato, K | 1 |
Cobanoğlu, S; Görgülü, A; Kiriş, T; Ozsüer, H | 1 |
De Deyn, PP; Van Dam, D | 1 |
Chu, K; Jung, KH; Kim, EH; Kim, J; Kim, M; Kim, SJ; Ko, SY; Lee, ST; Roh, JK; Sinn, DI | 1 |
Wang, R; Zhang, D | 1 |
Almeida, RC; Felisbino, CS; Gabilan, NH; López, MG; Rodrigues, AL | 1 |
Gupta, N; Kalichman, MW; Mizisin, AP; Weinreb, RN; Yücel, YH; Zhang, Q | 1 |
Creeley, C; Labruyere, J; Olney, JW; Taylor, GT; Wozniak, DF | 1 |
Lapchak, PA | 1 |
Bell, KF; Claudio Cuello, A | 1 |
Katsuragi, R; Murayama, N; Nakamura, S; Noshita, T; Ohno, T | 1 |
Chu, K; Jung, KH; Kang, L; Kim, M; Ko, SY; Lee, ST; Park, JE | 1 |
Barnes, CA; Ramirez-Amaya, V; Rosi, S; Vazdarjanova, A; Wenk, GL; Worley, PF | 1 |
Chu, K; Jung, KH; Kim, JM; Kim, M; Lee, ST; Park, DK; Roh, JK; Sinn, DI; Song, EC | 1 |
Adamis, AP; Ahmed, E; Bradley, J; Ng, YS; Robinson, GS; Schubert, W; Shima, DT; Zhong, L | 1 |
Back, T; Hennerici, MG; Kittner, D; Mennel, HD; Otto, D; Schüler, OG | 1 |
Belmin, J; Konrat, C; Pariel-Madjlessi, S; Péquignot, R | 1 |
Costa, AC; Scott-McKean, JJ; Stasko, MR | 1 |
Cheevers, CV; Donello, JE; Gil, DW | 1 |
Jung, SW; Kim, JH; Lee, NY; Park, CK | 1 |
Kneitz, S; Koutsilieri, E; Meisner, F; Neuen-Jacob, E; Riederer, P; Scheller, C; Sopper, S; ter Meulen, V | 1 |
Anderson, WG; Choi, DY; Drever, BD; Johnson, H; O'Callaghan, M; Platt, B; Riedel, G; Seo, S | 1 |
Aktan, D; Arica, O; Görgülü, A; Kirin, T; Sencer, A | 1 |
Devine, DP; Muehlmann, AM | 1 |
Coughlan, C; Csernansky, JG; Dong, H; Lewis, B; Yuede, CM | 1 |
Eisenberg, E; LaCross, S; Strassman, AM | 1 |
Chamuleau, RA; Daalhuisen, J; Maas, MA; Quack, G; Vogels, BA | 1 |
Bach, M; Feuerstein, TJ; Knörle, R; Lagrèze, WA | 1 |
Bienkowski, P; Danysz, W; Dyr, W; Koros, E; Kostowski, W; Piasecki, J | 1 |
Böck, P; Cartes-Zumelzu, F; Ciovica, R; Ehrlich, M; Fang, WC; Grabenwöger, M; Havel, M; Knolle, E; Kocher, A; Pockberger, H; Turkof, E; Wolner, E | 1 |
Kornhuber, J; Spanagel, R | 1 |
Le, DA; Lipton, SA; Sathi, S; Stieg, PE; Warach, S | 1 |
Danysz, W; Parsons, CG; Quack, G | 1 |
Miyamoto, KJ; Miyamoto, TA | 1 |
Gu, Z; Kawase, C; Kawase, K; Kitazawa, Y; Matsubara, M; Sawada, A; Yamamoto, T | 1 |
Lagrèze, WA | 1 |
Gordienko, DV; Krivobok, GK; Pankrat'ev, DV; Talalaenko, AN; Zinkovich, II | 1 |
Grehn, F | 1 |
12 review(s) available for memantine and Disease Models, Animal
Article | Year |
---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus | 2016 |
Improving the predictive value of interventional animal models data.
Topics: Alzheimer Disease; Animals; Cholinesterase Inhibitors; Data Mining; Databases, Factual; Disease Models, Animal; Donepezil; Drug Evaluation, Preclinical; Exercise Therapy; Humans; Indans; Memantine; Piperidines; Species Specificity; Systems Biology; Systems Integration; Translational Research, Biomedical | 2015 |
Alzheimer's disease in the zebrafish: where can we take it?
Topics: Alzheimer Disease; Animals; Dementia; Disease Models, Animal; Donepezil; Humans; Indans; Memantine; Methylene Blue; Piperidines; Rodentia; Species Specificity; Zebrafish | 2017 |
Neuroprotection: extrapolating from neurologic diseases to the eye.
Topics: Animals; Clinical Trials as Topic; Disease Models, Animal; Endpoint Determination; Excitatory Amino Acid Antagonists; Glaucoma, Open-Angle; Humans; Memantine; N-Methylaspartate; Nervous System Diseases; Neuroprotective Agents; Optic Nerve Diseases; Riluzole | 2009 |
[New perspectives on molecular and genic therapies in Down syndrome].
Topics: Animals; Catechin; Chromosomes, Human, Pair 21; Disease Models, Animal; Down Syndrome; Droxidopa; Drug Delivery Systems; Fluoxetine; Forecasting; Gene Expression Regulation; Genetic Association Studies; Genetic Therapy; Hedgehog Proteins; Humans; Memantine; Mice; Mice, Transgenic; Models, Genetic; Neuronal Plasticity; Neurotransmitter Agents; Pentylenetetrazole; Phenotype; Signal Transduction | 2010 |
Alzheimer's disease and age-related memory decline (preclinical).
Topics: Aging; Alzheimer Disease; Animals; Cholinesterase Inhibitors; Disease Models, Animal; Histamine H3 Antagonists; Humans; Ligands; Memantine; Memory Disorders; Nootropic Agents; Phosphodiesterase Inhibitors; Receptors, Muscarinic; Receptors, Nicotinic; Receptors, Serotonin; Translational Research, Biomedical | 2011 |
On the promise of pharmacotherapies targeted at cognitive and neurodegenerative components of Down syndrome.
Topics: Animals; Cognition Disorders; Disease Models, Animal; Down Syndrome; Excitatory Amino Acid Antagonists; Humans; Memantine; Nerve Degeneration; Randomized Controlled Trials as Topic; Translational Research, Biomedical | 2011 |
[Glutamate antagonists for treatment of neuropathic pain].
Topics: Amantadine; Animals; Disease Models, Animal; Excitatory Amino Acid Antagonists; Humans; Ketamine; Memantine; Neuralgia | 2003 |
[NMDA receptor antagonists: a new treatment for neuropathic pain].
Topics: Animals; Clinical Trials as Topic; Dextromethorphan; Disease Models, Animal; Excitatory Amino Acid Antagonists; Humans; Memantine; Neuralgia; Receptors, N-Methyl-D-Aspartate | 1999 |
Altered synaptic function in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Humans; Memantine; Mice; Mice, Transgenic; Neurites; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate; Synapses | 2006 |
[Management of Alzheimer disease].
Topics: Aged; Alzheimer Disease; Animals; Antipsychotic Agents; Caregivers; Case Management; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; Dopamine Agents; Excitatory Amino Acid Antagonists; Follow-Up Studies; Forecasting; Health Education; Humans; Indans; Memantine; Mental Disorders; Meta-Analysis as Topic; Nootropic Agents; Occupational Therapy; Piperidines; Practice Guidelines as Topic; Psychotropic Drugs; Randomized Controlled Trials as Topic; Time Factors | 2007 |
Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist--a review of preclinical data.
Topics: Animals; Brain; Disease Models, Animal; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Humans; Learning; Memantine; Neuroprotective Agents; Receptors, N-Methyl-D-Aspartate | 1999 |
2 trial(s) available for memantine and Disease Models, Animal
Article | Year |
---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; 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Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus | 2016 |
Memantine enhances recovery from stroke.
Topics: Animals; Behavior, Animal; Cerebral Cortex; Cerebral Infarction; Disease Models, Animal; Excitatory Amino Acid Antagonists; Memantine; Mice; Mice, Inbred C57BL; Random Allocation; Recovery of Function; Single-Blind Method; Stroke | 2014 |
228 other study(ies) available for memantine and Disease Models, Animal
Article | Year |
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In vitro and in vivo evaluation of polymethylene tetraamine derivatives as NMDA receptor channel blockers.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Memantine; Mice; Molecular Structure; Polyamines; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Thrombosis | 2013 |
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries | 2019 |
Rational design, synthesis and biological evaluation of novel multitargeting anti-AD iron chelators with potent MAO-B inhibitory and antioxidant activity.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Behavior, Animal; Binding Sites; Cell Survival; Coumarins; Disease Models, Animal; Drug Design; Humans; Iron Chelating Agents; Mice; Mice, Inbred ICR; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; PC12 Cells; Peptide Fragments; Rats; Structure-Activity Relationship | 2020 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Caenorhabditis elegans; Disease Models, Animal; Memantine; Mice; Receptors, N-Methyl-D-Aspartate | 2022 |
Astrocytic Kir4.1 regulates NMDAR/calpain signaling axis in lipopolysaccharide-induced depression-like behaviors in mice.
Topics: Animals; Antidepressive Agents; Astrocytes; Behavior, Animal; Calpain; Depression; Disease Models, Animal; Excitatory Amino Acid Antagonists; Hippocampus; Inflammasomes; Lipopolysaccharides; Male; Memantine; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Phosphorylation; Potassium Channels, Inwardly Rectifying; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2021 |
Effect of memantine on the survival of an ischemic random skin flap and the underlying mechanism.
Topics: Angiogenesis Inducing Agents; Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Graft Survival; Inflammation Mediators; Lipid Peroxidation; Male; Memantine; Neovascularization, Physiologic; Oxidative Stress; Rats, Sprague-Dawley; Reperfusion Injury; Skin; Skin Transplantation; Surgical Flaps; Up-Regulation; Vascular Endothelial Growth Factor A | 2021 |
Effects of Memantine and High Dose Vitamin D on Gait in Male APP/PS1 Alzheimer's Disease Mice Following Vitamin D Deprivation.
Topics: Alzheimer Disease; Animals; Disease Models, Animal; Gait Analysis; Male; Memantine; Mice; Mice, Transgenic; Vitamin D; Vitamin D Deficiency | 2022 |
Memantine treatment does not affect compulsive behavior or frontostriatal connectivity in an adolescent rat model for quinpirole-induced compulsive checking behavior.
Topics: Animals; Compulsive Behavior; Disease Models, Animal; Dopamine Agonists; Memantine; Obsessive-Compulsive Disorder; Quinpirole; Rats; Rats, Long-Evans; Rats, Sprague-Dawley | 2022 |
Propolis Promotes Memantine-Dependent Rescue of Cognitive Deficits in APP-KI Mice.
Topics: Adenosine Triphosphate; Alzheimer Disease; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cognition; Disease Models, Animal; Memantine; Mice; Mice, Transgenic; Propolis | 2022 |
Hypoxic and Hypercapnic Responses in Transgenic Murine Model of Alzheimer's Disease Overexpressing Human AβPP: The Effects of Pretreatment with Memantine and Rivastigmine.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Disease Models, Animal; Humans; Hypercapnia; Hypoxia; Memantine; Mice; Mice, Transgenic; Quality of Life; Respiration; Rivastigmine | 2022 |
Pharmacological Modulation of Glutamatergic and Neuroinflammatory Pathways in a Lafora Disease Mouse Model.
Topics: Adolescent; Animals; Disease Models, Animal; Dual-Specificity Phosphatases; Humans; Lafora Disease; Memantine; Mice; Mice, Knockout; Minocycline; Myoclonic Epilepsies, Progressive; Protein Tyrosine Phosphatases, Non-Receptor; Resveratrol; Ubiquitin-Protein Ligases | 2022 |
Glial cell reactivity and oxidative stress prevention in Alzheimer's disease mice model by an optimized NMDA receptor antagonist.
Topics: Alzheimer Disease; Animals; Arginase; Brain-Derived Neurotrophic Factor; Calcineurin; Calcium; Chitinases; Cytokines; Disease Models, Animal; Glial Fibrillary Acidic Protein; Memantine; Mice; Microglia; Nerve Growth Factor; NF-kappa B; Oxidative Stress; Receptors, N-Methyl-D-Aspartate | 2022 |
Does memantine show chemopreventive effect against mice 4T1 breast tumor model?
Topics: Animals; Disease Models, Animal; Female; Injections, Intraperitoneal; Interleukin-6; Memantine; Mice; Mice, Inbred BALB C | 2022 |
Memantine/Aripiprazole Combination Alleviates Cognitive Dysfunction in Valproic Acid Rat Model of Autism: Hippocampal CREB/BDNF Signaling and Glutamate Homeostasis.
Topics: Animals; Aripiprazole; Autism Spectrum Disorder; Autistic Disorder; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamates; Hippocampus; Homeostasis; Male; Memantine; Pregnancy; Rats; Rats, Wistar; Valproic Acid | 2023 |
Edaravone Improves Streptozotocin-Induced Memory Impairment via Alleviation of Behavioral Dysfunction, Oxidative Stress, Inflammation, and Histopathological Parameters.
Topics: Alzheimer Disease; Animals; Antioxidants; Disease Models, Animal; Donepezil; Edaravone; Inflammation; Male; Maze Learning; Memantine; Memory Disorders; Mice; Oxidative Stress; Rats; Rats, Wistar; Streptozocin | 2023 |
Effects of thymoquinone and memantine alone and in combination on memory and hippocampal morphology in rats with streptozotocin-induced Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Disease Models, Animal; Hippocampus; Male; Maze Learning; Memantine; Neurodegenerative Diseases; Rats; Streptozocin | 2023 |
Effects of the drug combination memantine and melatonin on impaired memory and brain neuronal deficits in an amyloid-predominant mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Cholinesterase Inhibitors; Disease Models, Animal; Drug Combinations; Female; Male; Maze Learning; Melatonin; Memantine; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Peptide Fragments | 2019 |
Lactoferrin Coupled Lower Generation PAMAM Dendrimers for Brain Targeted Delivery of Memantine in Aluminum-Chloride-Induced Alzheimer's Disease in Mice.
Topics: Aluminum Chloride; Alzheimer Disease; Animals; Brain; Cognition; Dendrimers; Disease Models, Animal; Dopamine; Drug Carriers; Drug Liberation; Erythrocytes; Lactoferrin; Memantine; Mice; Rats; Tissue Distribution | 2019 |
Gamma radiation preparation of chitosan nanoparticles for controlled delivery of memantine.
Topics: Acetic Acid; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antiparkinson Agents; Brain; Chitosan; Disease Models, Animal; Drug Compounding; Drug Liberation; Gamma Rays; Humans; Interleukins; Male; Memantine; Morris Water Maze Test; Nanocapsules; Rats; Solubility; Tumor Necrosis Factor-alpha; Water | 2020 |
Concomitant memantine and
Topics: Alzheimer Disease; Animals; Animals, Genetically Modified; Biomarkers; Choline; Cognitive Dysfunction; Dietary Supplements; Disease Models, Animal; Gastrointestinal Microbiome; Lactobacillus plantarum; Male; Memantine; Metagenomics; Mice; Probiotics; Pyramidal Cells | 2020 |
The pharmacokinetic parameters and the effect of a single and repeated doses of memantine on gastric myoelectric activity in experimental pigs.
Topics: Administration, Oral; Alzheimer Disease; Animals; Disease Models, Animal; Electromyography; Excitatory Amino Acid Antagonists; Female; Gastrointestinal Diseases; Gastrointestinal Motility; Humans; Memantine; Stomach; Sus scrofa | 2020 |
Positive allosteric modulators of alpha 7 nicotinic acetylcholine receptors enhance procognitive effects of conventional anti-Alzheimer drugs in scopolamine-treated rats.
Topics: Allosteric Regulation; alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Animals; Cholinergic Antagonists; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; Drug Synergism; Excitatory Amino Acid Antagonists; Galantamine; Isoxazoles; Memantine; Nootropic Agents; Phenylurea Compounds; Rats; Recognition, Psychology; Scopolamine | 2020 |
Withdrawal from Extended, Intermittent Access to A Highly Palatable Diet Impairs Hippocampal Memory Function and Neurogenesis: Effects of Memantine.
Topics: Animals; Behavior, Animal; Body Weight; Diet; Disease Models, Animal; Eating; Feeding and Eating Disorders; Food Addiction; Hippocampus; Male; Memantine; Memory; Memory Disorders; Neurogenesis; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2020 |
Modelling and treating GRIN2A developmental and epileptic encephalopathy in mice.
Topics: Animals; Dextromethorphan; Disease Models, Animal; Epilepsy, Generalized; Excitatory Amino Acid Antagonists; Gene Knock-In Techniques; Humans; Infant; Male; Memantine; Mice; Neurodevelopmental Disorders; Receptors, N-Methyl-D-Aspartate | 2020 |
Effect of memantine on expression of Bace1-as and Bace1 genes in STZ-induced Alzheimeric rats.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Antiparkinson Agents; Aspartic Acid Endopeptidases; Biomarkers; Brain; Disease Models, Animal; Gene Expression; Hippocampus; Male; Maze Learning; Memantine; Random Allocation; Rats; Rats, Wistar; RNA, Long Noncoding; Streptozocin | 2020 |
Memantine ameliorates motor impairments and pathologies in a mouse model of neuromyelitis optica spectrum disorders.
Topics: Animals; Apoptosis; Aquaporin 4; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; Humans; Immunoglobulin G; Memantine; Mice; Motor Disorders; Neuromyelitis Optica; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 2020 |
Delayed Adjunctive Treatment of Organophosphate-Induced Status Epilepticus in Rats with Phenobarbital, Memantine, or Dexmedetomidine.
Topics: Animals; Anticonvulsants; Brain; Cell Death; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Isoflurophate; Male; Memantine; Neurons; Phenobarbital; Prohibitins; Rats; Rats, Sprague-Dawley; Status Epilepticus; Time-to-Treatment; Treatment Outcome | 2020 |
Chronic Memantine Treatment Ameliorates Behavioral Deficits, Neuron Loss, and Impaired Neurogenesis in a Model of Alzheimer's Disease.
Topics: Administration, Oral; Alzheimer Disease; Animals; Anxiety; Behavior, Animal; CA1 Region, Hippocampal; Disease Models, Animal; Memantine; Mice, Transgenic; Motor Activity; Neurogenesis; Neurons; Open Field Test; Spatial Memory | 2021 |
Memantine effects on ingestion microstructure and the effect of administration time: A within-subject study.
Topics: Animals; Conditioning, Classical; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking Behavior; Eating; Feeding Behavior; Humans; Memantine; Memory; Rats; Receptors, N-Methyl-D-Aspartate | 2020 |
Anti-Amnesic and Neuroprotective Effects of Fluoroethylnormemantine in a Pharmacological Mouse Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Amnesia; Amyloid beta-Peptides; Animals; Behavior, Animal; Disease Models, Animal; Male; Memantine; Memory Disorders; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Peptide Fragments | 2021 |
Memantine and Ibuprofen pretreatment exerts anti-inflammatory effect against streptozotocin-induced astroglial inflammation via modulation of NMDA receptor-associated downstream calcium ion signaling.
Topics: Animals; Anti-Inflammatory Agents; Astrocytes; Calcium; Calcium Signaling; Cell Line, Tumor; Disease Models, Animal; Excitatory Amino Acid Antagonists; Ibuprofen; Inflammation; Memantine; Rats; Receptors, N-Methyl-D-Aspartate; Streptozocin | 2021 |
Antitumorigenic Effect of Memantine via Interfering Glutamate Metabolism in Mouse 4T1 Breast Tumor Model.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Proliferation; Disease Models, Animal; Drug Screening Assays, Antitumor; Female; Glutamic Acid; Memantine; Mice; Mice, Inbred BALB C; Tumor Cells, Cultured | 2021 |
The Tetramethylpyrazine Analogue T-006 Alleviates Cognitive Deficits by Inhibition of Tau Expression and Phosphorylation in Transgenic Mice Modeling Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Autophagy; Autophagy-Related Protein-1 Homolog; Avoidance Learning; Cognition Disorders; Disease Models, Animal; Donepezil; Drug Evaluation, Preclinical; Hydrazones; MAP Kinase Signaling System; Memantine; Mice; Mice, Transgenic; Morris Water Maze Test; Neuroprotective Agents; Phosphorylation; Protein Processing, Post-Translational; Pyrazines; Random Allocation; Recognition, Psychology; Signal Transduction; tau Proteins; TOR Serine-Threonine Kinases | 2021 |
Memantine ameliorates cognitive impairment induced by exposure to chronic hypoxia environment at high altitude by inhibiting excitotoxicity.
Topics: Altitude; Altitude Sickness; Alzheimer Disease; Animals; Cell Death; Cognition; Cognitive Dysfunction; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Hypoxia; Male; Memantine; Memory; Neurons; Neuroprotective Agents; Neurotoxins; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2021 |
Effect of Memantine on Pentylenetetrazol-induced Seizures and EEG Profile in Animal Model of Cortical Malformation.
Topics: Animals; Disease Models, Animal; Electroencephalography; Male; Memantine; Pentylenetetrazole; Rats; Rats, Wistar; Seizures | 2021 |
Memantine protects blood-brain barrier integrity and attenuates neurological deficits through inhibiting nitric oxide synthase ser1412 phosphorylation in intracerebral hemorrhage rats: involvement of peroxynitrite-related matrix metalloproteinase-9/NLRP3
Topics: Animals; Blood-Brain Barrier; Brain Edema; Cerebral Hemorrhage; Collagenases; Disease Models, Animal; Gelatinases; Inflammasomes; Interleukin-1beta; Matrix Metalloproteinase 9; Memantine; Neuroprotective Agents; Nitric Oxide Synthase Type I; NLR Family, Pyrin Domain-Containing 3 Protein; Peroxynitrous Acid; Phosphorylation; Rats | 2021 |
Effect of Memantine Treatment and Combination with Vitamin D Supplementation on Body Composition in the APP/PS1 Mouse Model of Alzheimer's Disease Following Chronic Vitamin D Deficiency.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Body Composition; Dietary Supplements; Disease Models, Animal; Dopamine Agents; Male; Memantine; Mice; Mice, Transgenic; Presenilin-1; Vitamin D; Vitamin D Deficiency | 2021 |
Therapeutic efficacy of novel memantine nitrate MN-08 in animal models of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Disease Models, Animal; Memantine; Mice; Mice, Transgenic | 2021 |
[Effects of Yokukansankachimpihange on Memantine-induced Dizziness in Mice with Memory Impairment].
Topics: Administration, Oral; Alzheimer Disease; Animals; Disease Models, Animal; Dizziness; Drug Therapy, Combination; Drugs, Chinese Herbal; Male; Memantine; Memory Disorders; Mice, Inbred Strains; Phytotherapy; Receptors, N-Methyl-D-Aspartate | 2021 |
Discovery of memantyl urea derivatives as potent soluble epoxide hydrolase inhibitors against lipopolysaccharide-induced sepsis.
Topics: Animals; Binding Sites; Catalytic Domain; Disease Models, Animal; Drug Design; Enzyme Inhibitors; Epoxide Hydrolases; Female; Humans; Lipopolysaccharides; Male; Memantine; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Rats; Sepsis; Structure-Activity Relationship; Survival Rate; Urea | 2021 |
Memantine and Riluzole Exacerbate, Rather Than Ameliorate Behavioral Deficits Induced by 8-OH-DPAT Sensitization in a Spatial Task.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Disease Models, Animal; Male; Memantine; Memory; Obsessive-Compulsive Disorder; Rats; Rats, Long-Evans; Riluzole; Spatial Learning | 2021 |
Protective Effect of Memantine on Bergmann Glia and Purkinje Cells Morphology in Optogenetic Model of Neurodegeneration in Mice.
Topics: Animals; Disease Models, Animal; Dopamine Agents; Memantine; Mice; Neurodegenerative Diseases; Neuroglia; Optogenetics; Protective Agents; Purkinje Cells | 2021 |
Memantine improves outcomes after repetitive traumatic brain injury.
Topics: Animals; Behavior, Animal; Brain Concussion; Cerebral Cortex; Disease Models, Animal; Excitatory Amino Acid Antagonists; Hippocampus; Male; Memantine; Mice, Inbred C57BL; Microglia; Neuroprotective Agents; Random Allocation; Receptors, N-Methyl-D-Aspartate; Tissue Culture Techniques | 2018 |
Spatial recognition test: A novel cognition task for assessing topographical memory in mice.
Topics: Alzheimer Disease; Animals; Cognition; Disease Models, Animal; Donepezil; Indans; Levetiracetam; Male; Maze Learning; Memantine; Memory; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nootropic Agents; Piperidines; Piracetam; Recognition, Psychology | 2017 |
Pharmacokinetic Properties of Memantine after a Single Intraperitoneal Administration and Multiple Oral Doses in Euploid Mice and in the Ts65Dn Mouse Model of Down's Syndrome.
Topics: Administration, Oral; Animals; Brain; Disease Models, Animal; Down Syndrome; Excitatory Amino Acid Antagonists; Female; Gas Chromatography-Mass Spectrometry; Injections, Intraperitoneal; Liver; Male; Memantine; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Tissue Distribution | 2017 |
Effect of Gabapentin/Memantine on the Infantile Nystagmus Syndrome in the Zebrafish Model: Implications for the Therapy of Ocular Motor Diseases.
Topics: Amines; Animals; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Disease Models, Animal; Excitatory Amino Acid Antagonists; Eye Movements; Gabapentin; gamma-Aminobutyric Acid; Memantine; Nystagmus, Congenital; Syndrome; Zebrafish | 2017 |
Effects of acute administration of donepezil or memantine on sleep-deprivation-induced spatial memory deficit in young and aged non-human primate grey mouse lemurs (Microcebus murinus).
Topics: Aging; Alzheimer Disease; Animals; Cheirogaleidae; Disease Models, Animal; Donepezil; Indans; Male; Memantine; Memory Disorders; Piperidines; Sleep Deprivation; Spatial Memory | 2017 |
S-sulfocysteine/NMDA receptor-dependent signaling underlies neurodegeneration in molybdenum cofactor deficiency.
Topics: Animals; Calcium Signaling; Cysteine; Disease Models, Animal; GABAergic Neurons; HEK293 Cells; Humans; Memantine; Metal Metabolism, Inborn Errors; Mice; Neurodegenerative Diseases; Organophosphorus Compounds; Pterins; Receptors, N-Methyl-D-Aspartate; Synapses; Tungsten Compounds | 2017 |
NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism.
Topics: Animals; Autistic Disorder; Behavior, Animal; Biomarkers; Brain; Cell Death; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Antagonists; Gene Expression Profiling; Haploinsufficiency; Humans; Long-Term Potentiation; MEF2 Transcription Factors; Memantine; Mice, Inbred C57BL; Neurogenesis; Neurons; Phenotype; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 2017 |
Galantamine and memantine combination for cognition: Enough or more than enough to translate from murines and macaques to men with schizophrenia?
Topics: Animals; Disease Models, Animal; Drug Therapy, Combination; Galantamine; Humans; Memantine; Neurotransmitter Agents; Nootropic Agents | 2019 |
Tramadol ameliorates behavioural, biochemical, mitochondrial and histological alterations in ICV-STZ-induced sporadic dementia of Alzheimer's type in rats.
Topics: Alzheimer Disease; Animals; Behavior, Animal; Dementia; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Memantine; Mitochondria; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley; Streptozocin; Tramadol | 2018 |
Loss of kallikrein-related peptidase 7 exacerbates amyloid pathology in Alzheimer's disease model mice.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Astrocytes; Brain; Cell Line, Tumor; Culture Media, Conditioned; Disease Models, Animal; Humans; Kallikreins; Memantine; Mice, Knockout; Proteolysis; RNA, Messenger; Up-Regulation | 2018 |
Neuroprotective effects of topiramate and memantine in combination with hypothermia in hypoxic-ischemic brain injury in vitro and in vivo.
Topics: Animals; Animals, Newborn; Combined Modality Therapy; Disease Models, Animal; Fructose; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Memantine; Neuroprotective Agents; Rats; Rats, Wistar; Topiramate | 2018 |
The Effects of Memantine on Glutamic Receptor-Associated Nitrosative Stress in a Traumatic Brain Injury Rat Model.
Topics: Animals; Apoptosis; Brain Injuries, Traumatic; Disease Models, Animal; Male; Memantine; Neuroprotective Agents; Nitrosative Stress; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recovery of Function | 2018 |
Peripheral and Central Effects of Memantine in a Mixed Preclinical Mice Model of Obesity and Familial Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Body Weight; Cognition; Diet, High-Fat; Disease Models, Animal; Feeding Behavior; Genotype; Inflammation; Insulin; Liver; Male; Memantine; Mice, Inbred C57BL; Mice, Transgenic; Models, Biological; Obesity; Plaque, Amyloid; Signal Transduction | 2018 |
Effects of Memantine on Nitric Oxide Production and Hydroxyl Radical Metabolism during Cerebral Ischemia and Reperfusion in Mice.
Topics: Animals; Antioxidants; Biomarkers; Blood Flow Velocity; Brain Ischemia; CA1 Region, Hippocampal; Cerebrovascular Circulation; Cytoprotection; Disease Models, Animal; Hydroxyl Radical; Memantine; Mice, Inbred C57BL; Microdialysis; Neurons; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Reperfusion Injury; Time Factors | 2018 |
Memantine loaded PLGA PEGylated nanoparticles for Alzheimer's disease: in vitro and in vivo characterization.
Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antiparkinson Agents; Astrocytes; Blood-Brain Barrier; Cell Line; Cell Survival; Cognitive Dysfunction; Disease Models, Animal; Drug Carriers; Drug Compounding; Emulsions; Humans; Male; Maze Learning; Memantine; Mice; Mice, Transgenic; Nanoparticles; Neurons; Particle Size; Plaque, Amyloid; Polyesters; Polyethylene Glycols | 2018 |
Memantine treatment of juvenile rats with kaolin-induced hydrocephalus.
Topics: Animals; Body Weight; Cerebral Ventricles; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; Hydrocephalus; Kaolin; Male; Memantine; Motor Activity; Neuroprotective Agents; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Single-Blind Method; White Matter | 2018 |
Memantine ameliorates depressive-like behaviors by regulating hippocampal cell proliferation and neuroprotection in olfactory bulbectomized mice.
Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cell Proliferation; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Depressive Disorder; Disease Models, Animal; Dopamine; Extracellular Signal-Regulated MAP Kinases; Hippocampus; Inflammation; Male; Memantine; Mice; Microglia; Neuroprotective Agents; Olfactory Bulb | 2018 |
Pharmacological Modulation of Three Modalities of CA1 Hippocampal Long-Term Potentiation in the Ts65Dn Mouse Model of Down Syndrome.
Topics: Amyloid beta-Peptides; Animals; CA1 Region, Hippocampal; Disease Models, Animal; Down Syndrome; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Humans; Long-Term Potentiation; Male; Memantine; Mice, Inbred C57BL; Mice, Transgenic; Picrotoxin; Prion Proteins | 2018 |
Connectomic imaging reveals Huntington-related pathological and pharmaceutical effects in a mouse model.
Topics: Animals; Axons; Behavior, Animal; Cognition; Connectome; Disease Models, Animal; Electric Stimulation; Humans; Huntington Disease; Magnetic Resonance Imaging; Male; Memantine; Mice; Motor Activity; Nerve Net; Oxygen; Rest; Somatosensory Cortex; Structure-Activity Relationship | 2018 |
N-methyl-D-aspartate receptor-mediated calcium influx connects amyloid-β oligomers to ectopic neuronal cell cycle reentry in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Calcium; Cell Cycle; Cells, Cultured; Disease Models, Animal; Excitatory Amino Acid Antagonists; HEK293 Cells; Humans; Intracellular Space; Memantine; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Receptors, N-Methyl-D-Aspartate | 2018 |
Pore-former enabled seeding of tau in rats: Alleviation by memantine and lithium chloride.
Topics: Alzheimer Disease; Animals; CA1 Region, Hippocampal; Disease Models, Animal; Lithium Chloride; Male; Memantine; Neurons; Neuroprotective Agents; Phosphorylation; Polymers; Pyridinium Compounds; Rats, Wistar; Recombinant Proteins; tau Proteins; Tauopathies | 2019 |
Early Correction of N-Methyl-D-Aspartate Receptor Function Improves Autistic-like Social Behaviors in Adult Shank2
Topics: Age Factors; Animals; Autism Spectrum Disorder; Behavior, Animal; Disease Models, Animal; Excitatory Amino Acid Antagonists; Memantine; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Receptors, N-Methyl-D-Aspartate; Social Behavior | 2019 |
Neuro-metabolite profiles of rodent models of psychiatric dysfunctions characterised by MR spectroscopy.
Topics: Anhedonia; Animals; Choline; Depression; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutamine; Hippocampus; Inositol; Magnetic Resonance Spectroscopy; Male; Memantine; Motor Activity; Rats; Rats, Wistar; Schizophrenia; Stress, Psychological; Sucrose; Taurine | 2019 |
Prophylactic potential of memantine against soman poisoning in rats.
Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Behavior, Animal; Chemical Warfare Agents; Cholinesterase Inhibitors; Diazepam; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; GPI-Linked Proteins; Male; Memantine; Neuromuscular Junction; Organophosphate Poisoning; Oximes; Pyridinium Compounds; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Soman; Synaptic Transmission | 2019 |
In silico identification of critical proteins associated with learning process and immune system for Down syndrome.
Topics: Animals; Bayes Theorem; Computer Simulation; Disease Models, Animal; Down Syndrome; Gene Expression; Humans; Immune System Phenomena; Learning; Memantine; Mice; Nerve Tissue Proteins; Neural Networks, Computer; Support Vector Machine; Trisomy | 2019 |
No effect of riluzole and memantine on learning deficit following quinpirole sensitization - An animal model of obsessive-compulsive disorder.
Topics: Animals; Behavior, Animal; Cognition; Disease Models, Animal; Dopamine Agonists; Excitatory Amino Acid Antagonists; Learning; Male; Memantine; Motor Activity; Obsessive-Compulsive Disorder; Quinpirole; Rats; Rats, Long-Evans; Riluzole | 2019 |
Administration of memantine reverses behavioral, histological, and electrophysiological abnormalities in rats subjected to early maternal deprivation.
Topics: Animals; Animals, Newborn; Auditory Cortex; Behavior, Animal; Cognitive Dysfunction; Corpus Striatum; Disease Models, Animal; Evoked Potentials; Excitatory Amino Acid Antagonists; Female; Hippocampus; Male; Maternal Deprivation; Maze Learning; Memantine; Prefrontal Cortex; Pregnancy; Rats; Rats, Sprague-Dawley; Schizophrenia | 2019 |
Memantine ameliorates learning and memory disturbance and the behavioral and psychological symptoms of dementia in thiamine-deficient mice.
Topics: Administration, Oral; Animals; Anxiety; Behavior, Animal; Biogenic Monoamines; Body Weight; Dementia; Depression; Disease Models, Animal; Glutamic Acid; Hippocampus; Locomotion; Male; Maze Learning; Memantine; Memory; Mice; Thiamine Deficiency | 2019 |
Acute and chronic effects of single dose memantine after controlled cortical impact injury in adult rats.
Topics: Animals; Behavior, Animal; Brain Injuries, Traumatic; Cerebral Cortex; Disease Models, Animal; Excitatory Amino Acid Antagonists; Hippocampus; Male; Memantine; Motor Activity; Nerve Degeneration; Rats; Receptors, N-Methyl-D-Aspartate; Spatial Memory; Time Factors; Vestibule, Labyrinth | 2019 |
The dual-functional memantine nitrate MN-08 alleviates cerebral vasospasm and brain injury in experimental subarachnoid haemorrhage models.
Topics: Animals; Brain Injuries; Disease Models, Animal; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Male; Memantine; Mice; Mice, Inbred C57BL; Nimodipine; Nitrates; Nitric Oxide; Rabbits; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Subarachnoid Hemorrhage; Vasodilator Agents; Vasospasm, Intracranial | 2019 |
Effect of memantine hydrochloride on cisplatin-induced neurobehavioral toxicity in mice.
Topics: Animals; Antineoplastic Agents; Behavior, Animal; Cisplatin; Disease Models, Animal; Excitatory Amino Acid Antagonists; Male; Memantine; Mice, Inbred BALB C; N-Methylaspartate; Neuroprotective Agents; Neurotoxicity Syndromes; Psychomotor Performance | 2020 |
Altered NMDAR signaling underlies autistic-like features in mouse models of CDKL5 deficiency disorder.
Topics: Animals; Behavior, Animal; Codon, Nonsense; Disease Models, Animal; Epileptic Syndromes; Excitatory Amino Acid Antagonists; Female; GABAergic Neurons; Humans; Male; Memantine; Mice; Mice, Inbred C57BL; Mice, Knockout; Prosencephalon; Protein Serine-Threonine Kinases; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Spasms, Infantile; Treatment Outcome | 2019 |
Functional protective effects of long-term memantine treatment in the DBA/2J mouse.
Topics: Animals; Disease Models, Animal; Dopamine Agents; Electroretinography; Female; Follow-Up Studies; Glaucoma, Angle-Closure; Intraocular Pressure; Memantine; Mice; Mice, Inbred DBA; Microscopy, Confocal; Retina; Time Factors; Treatment Outcome | 2013 |
Neurorestorative effect of FTY720 in a rat model of Alzheimer's disease: comparison with memantine.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Avoidance Learning; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fingolimod Hydrochloride; Gene Expression Profiling; Gene Expression Regulation; Hippocampus; Male; Memantine; Mitogen-Activated Protein Kinases; Nerve Degeneration; Neuroprotective Agents; Peptide Fragments; Propylene Glycols; Rats; Rats, Sprague-Dawley; Sex Factors; Sphingosine | 2013 |
Reduced CNS exposure of memantine in a triple transgenic mouse model of Alzheimer's disease assessed using a novel LC-MS technique.
Topics: Alzheimer Disease; Animals; Blood-Brain Barrier; Brain; Chromatography, Liquid; Disease Models, Animal; Male; Mass Spectrometry; Memantine; Mice; Mice, Transgenic | 2013 |
Treatment of the Ppt1(-/-) mouse model of infantile neuronal ceroid lipofuscinosis with the N-methyl-D-aspartate (NMDA) receptor antagonist memantine.
Topics: Animals; Disease Models, Animal; Disease Progression; Excitatory Amino Acid Antagonists; Memantine; Mice; Mice, Knockout; Motor Activity; Neuronal Ceroid-Lipofuscinoses; Receptors, N-Methyl-D-Aspartate; Rotarod Performance Test; Thiolester Hydrolases; Treatment Outcome | 2013 |
Effect of cyanocobalamin (vitamin B12) in the induction and expression of morphine tolerance and dependence in mice.
Topics: Analgesics, Opioid; Animals; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Male; Memantine; Mice; Morphine; Morphine Dependence; Naloxone; Pain; Vitamin B 12 | 2014 |
Neuroprotective and cognitive enhancing effects of a multi-targeted food intervention in an animal model of neurodegeneration and depression.
Topics: Animals; Atrophy; Cell Death; Cognition Disorders; Depressive Disorder; Disease Models, Animal; Hippocampus; Male; Memantine; Memory Disorders; Neurodegenerative Diseases; Neuroimmunomodulation; Neuroprotective Agents; Nootropic Agents; Olfaction Disorders; Olfactory Bulb; Psychomotor Agitation; Rats; Rats, Sprague-Dawley; Space Perception; Zinc Sulfate | 2014 |
Efficacy of local polymer-based and systemic delivery of the anti-glutamatergic agents riluzole and memantine in rat glioma models.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Disease Models, Animal; Drug Delivery Systems; Excitatory Amino Acid Antagonists; Glioma; Memantine; Mice; Polymers; Rats; Riluzole | 2014 |
Effect of memantine on L-DOPA-induced dyskinesia in the 6-OHDA-lesioned rat model of Parkinson's disease.
Topics: Amantadine; Animals; Antiparkinson Agents; Disease Models, Animal; Dyskinesias; Excitatory Amino Acid Antagonists; Levodopa; Male; Memantine; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley | 2014 |
The effect of memantine on functional recovery of the facial nerve after crush injury.
Topics: Animals; Disease Models, Animal; Excitatory Amino Acid Antagonists; Facial Injuries; Facial Nerve; Facial Nerve Injuries; Female; Memantine; Rats; Rats, Wistar; Recovery of Function | 2015 |
Low doses of dextromethorphan have a beneficial effect in the treatment of neuropathic pain.
Topics: Animals; Cognition; Dextromethorphan; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hyperalgesia; Male; Maze Learning; Memantine; Neuralgia; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2014 |
Role of glutamate and advantages of combining memantine with a 5HT6 ligand in a model of depression.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Glutamic Acid; Ligands; Male; Memantine; Motor Activity; N-Methylaspartate; Piperazines; Prefrontal Cortex; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Sulfonamides; Swimming | 2014 |
Memantine reduces alcohol drinking but not relapse in alcohol-dependent rats.
Topics: Alcohol Drinking; Alcoholism; Animals; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Memantine; Motivation; Motor Activity; Rats; Rats, Long-Evans; Recurrence | 2015 |
The neuroprotective effect of 17β-estradiol is independent of its antioxidative properties.
Topics: Animals; Antioxidants; Body Weight; Brain; Brain Infarction; Cresols; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Hormones; Infarction, Middle Cerebral Artery; Male; Memantine; Mice, Inbred C57BL; Motor Activity; Neuroprotective Agents | 2014 |
Memantine delayed N-methyl-D-aspartate -induced convulsions in neonatal rats.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Female; Male; Memantine; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures | 2015 |
Delayed preconditioning with NMDA receptor antagonists in a rat model of perinatal asphyxia.
Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Brain; Brain Ischemia; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gerbillinae; Immunohistochemistry; Ischemic Preconditioning; Male; Memantine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2014 |
The uncompetitive N-methyl-D-aspartate antagonist memantine reduces binge-like eating, food-seeking behavior, and compulsive eating: role of the nucleus accumbens shell.
Topics: Animal Feed; Animals; Binge-Eating Disorder; Compulsive Behavior; Conditioning, Operant; Conflict, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Eating; Excitatory Amino Acid Antagonists; Fasting; Feeding Behavior; Lighting; Male; Memantine; Motivation; Nucleus Accumbens; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule | 2015 |
Treatment with UDP-glucose, GDNF, and memantine promotes SVZ and white matter self-repair by endogenous glial progenitor cells in neonatal rats with ischemic PVL.
Topics: Animals; Animals, Newborn; Brain; Brain Ischemia; Cell Hypoxia; Cell Proliferation; Cell Survival; Cells, Cultured; Disease Models, Animal; Glial Cell Line-Derived Neurotrophic Factor; Glucose; Leukomalacia, Periventricular; Memantine; Neural Stem Cells; Neurogenesis; Neuroglia; Neuroprotective Agents; Random Allocation; Rats, Inbred SHR; Stem Cell Niche; Uridine Diphosphate Glucose; White Matter | 2015 |
MPTP-induced changes in hippocampal synaptic plasticity and memory are prevented by memantine through the BDNF-TrkB pathway.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Antiparkinson Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Calcium Signaling; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Hippocampus; In Vitro Techniques; Male; Memantine; Membrane Glycoproteins; Memory Disorders; Memory, Long-Term; Mice, Inbred C57BL; Neuronal Plasticity; Parkinsonian Disorders; Protein-Tyrosine Kinases; Signal Transduction; Synapses; Time Factors | 2015 |
A Combination Therapy of 17β-Estradiol and Memantine Is More Neuroprotective Than Monotherapies in an Organotypic Brain Slice Culture Model of Traumatic Brain Injury.
Topics: Animals; Brain Injuries; Disease Models, Animal; Drug Therapy, Combination; Estradiol; Estrogens; Hippocampus; Memantine; Neuroprotective Agents; Organ Culture Techniques; Rats; Rats, Sprague-Dawley | 2015 |
Protein dynamics associated with failed and rescued learning in the Ts65Dn mouse model of Down syndrome.
Topics: Animals; Disease Models, Animal; Down Syndrome; Learning; Memantine; Mice; Protein Subunits; Proteome; Proteomics; Receptors, N-Methyl-D-Aspartate | 2015 |
Neuroprotective effect of memantine on the retinal ganglion cells of APPswe/PS1ΔE9 mice and its immunomodulatory mechanisms.
Topics: Alzheimer Disease; Analysis of Variance; Animals; Disease Models, Animal; Electroretinography; Ependymoglial Cells; Evoked Potentials, Visual; Glutamate-Ammonia Ligase; MAP Kinase Signaling System; Memantine; Mice; Mice, Transgenic; Microglia; Nerve Degeneration; Neuroprotective Agents; Phosphorylation; Retinal Ganglion Cells | 2015 |
NMDA Receptor Antagonist Attenuates Bleomycin-Induced Acute Lung Injury.
Topics: Acute Lung Injury; Amino Acids; Animals; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar Lavage Fluid; Capillary Permeability; CD11b Antigen; Cytokines; Disease Models, Animal; Dopamine Agents; Female; Glutamic Acid; Malondialdehyde; Memantine; Mice; Neutrophil Infiltration; Neutrophils; Receptors, N-Methyl-D-Aspartate | 2015 |
Memantine Attenuates Delayed Vasospasm after Experimental Subarachnoid Hemorrhage via Modulating Endothelial Nitric Oxide Synthase.
Topics: Animals; Blotting, Western; Disease Models, Animal; Endothelium, Vascular; Excitatory Amino Acid Antagonists; Male; Memantine; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Subarachnoid Hemorrhage; Vasospasm, Intracranial | 2015 |
Self-Organizing Feature Maps Identify Proteins Critical to Learning in a Mouse Model of Down Syndrome.
Topics: Animals; Cluster Analysis; Disease Models, Animal; Down Syndrome; Gene Expression Regulation; Humans; Learning; Memantine; Memory Disorders; Mice; Protein Interaction Maps | 2015 |
Enhancing glutamatergic transmission during adolescence reverses early-life stress-induced deficits in the rewarding effects of cocaine in rats.
Topics: Administration, Intravenous; Aging; Amino Acid Transport System X-AG; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Maternal Deprivation; Memantine; Rats; Receptors, N-Methyl-D-Aspartate; Reward; Riluzole; Self Administration; Stress, Psychological | 2015 |
CIH-induced neurocognitive impairments are associated with hippocampal Ca(2+) overload, apoptosis, and dephosphorylation of ERK1/2 and CREB that are mediated by overactivation of NMDARs.
Topics: Analysis of Variance; Animals; Apoptosis; Calcium; Cognition Disorders; CREB-Binding Protein; Disease Models, Animal; Excitatory Amino Acid Antagonists; Flow Cytometry; Hippocampus; Hypoxia; Male; MAP Kinase Signaling System; Maze Learning; Memantine; Mice; Mice, Inbred ICR; Receptors, N-Methyl-D-Aspartate; Time Factors | 2015 |
Pharmacokinetics of Memantine after a Single and Multiple Dose of Oral and Patch Administration in Rats.
Topics: Administration, Cutaneous; Administration, Intravenous; Administration, Oral; Alzheimer Disease; Animals; Area Under Curve; Biological Availability; Disease Models, Animal; Dose-Response Relationship, Drug; Half-Life; Memantine; Nootropic Agents; Rats; Transdermal Patch | 2016 |
Long-lasting effect of NMDA receptor antagonist memantine on ethanol-cue association and relapse.
Topics: Alcoholism; Animals; Conditioning, Psychological; Cues; Disease Models, Animal; Ethanol; Extinction, Psychological; Male; Memantine; Memory; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Recurrence; Self Administration | 2015 |
Protection by sigma-1 receptor agonists is synergic with donepezil, but not with memantine, in a mouse model of amyloid-induced memory impairments.
Topics: Amyloid beta-Peptides; Animals; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; Drug Synergism; Excitatory Amino Acid Antagonists; Furans; Indans; Male; Memantine; Memory Disorders; Mice; Morpholines; Neuroprotective Agents; Peptide Fragments; Piperidines; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sigma-1 Receptor | 2016 |
Protective effects of NMDA receptor antagonist, memantine, against senescence of PC12 cells: A possible role of nNOS and combined effects with donepezil.
Topics: Aging; Alzheimer Disease; Animals; beta-Galactosidase; Cholinesterase Inhibitors; Cognition; Disease Models, Animal; Donepezil; Glutamic Acid; Hippocampus; Indans; Male; Maze Learning; Memantine; Memory; Mice; Neuronal Plasticity; Nitric Oxide Synthase Type I; PC12 Cells; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate | 2015 |
Memantine Attenuates Alzheimer's Disease-Like Pathology and Cognitive Impairment.
Topics: Alzheimer Disease; Animals; Behavior, Animal; Blotting, Western; Cognition Disorders; Dependovirus; Disease Models, Animal; Dopamine Agents; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Intracellular Signaling Peptides and Proteins; Male; Memantine; Nuclear Proteins; Protein Phosphatase 2; Rats; Rats, Wistar; RNA-Binding Proteins | 2015 |
Elevated glucose and oligomeric β-amyloid disrupt synapses via a common pathway of aberrant protein S-nitrosylation.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Case-Control Studies; Cerebral Cortex; Dendritic Spines; Diabetes Mellitus, Type 2; Disease Models, Animal; Dynamins; Excitatory Amino Acid Antagonists; Female; Glucose; GTP Phosphohydrolases; Hippocampus; Humans; Hyperglycemia; Immunoblotting; Induced Pluripotent Stem Cells; Insulin; Insulysin; Long-Term Potentiation; Male; Memantine; Metabolic Syndrome; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Mitochondrial Proteins; Neurons; Nitric Oxide; Nitroso Compounds; Oxygen Consumption; Rats; Reactive Nitrogen Species; Synapses | 2016 |
NMDA receptor is involved in neuroinflammation in intracerebroventricular colchicine-injected rats.
Topics: Alzheimer Disease; Animals; Cell Adhesion; Colchicine; Cytotoxicity, Immunologic; Disease Models, Animal; Humans; Immunomodulation; Inflammation Mediators; Infusions, Intraventricular; Male; Memantine; Mice; Neurogenic Inflammation; Neurotoxins; Phagocytosis; Rats; Receptors, N-Methyl-D-Aspartate | 2016 |
Cognitive benefits of memantine in Alzheimer's 5XFAD model mice decline during advanced disease stages.
Topics: Alzheimer Disease; Animals; Cognition Disorders; Disease Models, Animal; Dopamine Agents; Memantine; Mice; Mice, Inbred C57BL; Mice, Transgenic | 2016 |
Effects of Memantine on Aminoglycoside-Induced Apoptosis of Spiral Ganglion Cells in Guinea Pigs.
Topics: Animals; Apoptosis; Blotting, Western; Cochlea; Disease Models, Animal; Gentamicins; Guinea Pigs; In Situ Nick-End Labeling; Memantine; Republic of Korea; Signal Transduction; Spiral Ganglion | 2016 |
Memantine ameliorates autistic behavior, biochemistry & blood brain barrier impairments in rats.
Topics: Animals; Autistic Disorder; Blood-Brain Barrier; Brain; Disease Models, Animal; Excitatory Amino Acid Antagonists; Exploratory Behavior; Female; Interpersonal Relations; Locomotion; Male; Maze Learning; Memantine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Valproic Acid | 2016 |
GluN3A promotes NMDA spiking by enhancing synaptic transmission in Huntington's disease models.
Topics: Animals; Corpus Striatum; Disease Models, Animal; Glutamic Acid; Huntington Disease; Memantine; Mice; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 2016 |
Memantine improves memory impairment and depressive-like behavior induced by amphetamine withdrawal in rats.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Antidepressive Agents; Central Nervous System Stimulants; Depression; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Imipramine; Male; Memantine; Memory Disorders; Muscarinic Antagonists; Nootropic Agents; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Scopolamine; Substance Withdrawal Syndrome | 2016 |
Modeling and simulation of organophosphate-induced neurotoxicity: Prediction and validation by experimental studies.
Topics: Acetylcholinesterase; Animals; Brain Waves; Cholinesterase Reactivators; Computer Simulation; Disease Models, Animal; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Male; Memantine; Membrane Potentials; Mice; Models, Neurological; Neurons; Neurotoxicity Syndromes; Organophosphates; Oximes; Paraoxon; Pyridinium Compounds | 2016 |
Insulin potentiates the therapeutic effect of memantine against central STZ-induced spatial learning and memory deficit.
Topics: Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Insulin; Male; Maze Learning; Memantine; Memory Disorders; Motor Activity; Nootropic Agents; Rats, Sprague-Dawley; Spatial Memory; Visual Perception | 2016 |
The combination of memantine and galantamine improves cognition in rats: The synergistic role of the α7 nicotinic acetylcholine and NMDA receptors.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Animals; Antiparkinson Agents; Cholinesterase Inhibitors; Cognition; Disease Models, Animal; Galantamine; Male; Memantine; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic | 2016 |
Memantine and Q-VD-OPh Treatments in Experimental Spinal Cord Injury: Combined Inhibition of Necrosis and Apoptosis.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Male; Memantine; Necrosis; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord Injuries | 2016 |
Microglia-Based Phenotypic Screening Identifies a Novel Inhibitor of Neuroinflammation Effective in Alzheimer's Disease Models.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cognition; Disease Models, Animal; Donepezil; Dose-Response Relationship, Drug; Drug Discovery; Drug Evaluation, Preclinical; Female; Indans; Male; Memantine; Memory; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Neuroimmunomodulation; Neuroprotective Agents; Peptide Fragments; Phenotype; Piperazines; Piperidines; Pyridazines; Random Allocation; Rats, Sprague-Dawley | 2016 |
Combining hypobaric hypoxia or hyperbaric oxygen postconditioning with memantine reduces neuroprotection in 7-day-old rat hypoxia-ischemia.
Topics: Animals; Animals, Newborn; Apoptosis; CA1 Region, Hippocampal; Disease Models, Animal; Hyperbaric Oxygenation; Hypoxia; Hypoxia-Ischemia, Brain; Memantine; Neuroprotection; Neuroprotective Agents; Oxygen; Rats; Rats, Wistar; Reactive Oxygen Species | 2016 |
Low dose of L-glutamic acid attenuated the neurological dysfunctions and excitotoxicity in bilateral common carotid artery occluded mice.
Topics: Animals; Brain; Brain Ischemia; Carotid Artery, Common; Disease Models, Animal; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamic Acid; Glutathione; Male; Memantine; Mice; Neuroprotective Agents; Nitric Oxide; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; Time Factors | 2016 |
Differential regulation of GluA1 expression by ketamine and memantine.
Topics: Animals; Benzylamines; Depression; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Ketamine; Memantine; Phosphinic Acids; Phosphorylation; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Swimming; Synaptic Transmission; Synaptosomes | 2017 |
In Vivo Characterization of ARN14140, a Memantine/Galantamine-Based Multi-Target Compound for Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Galantamine; Memantine; Mice; Mice, Transgenic; Peptide Fragments | 2016 |
Blockade of the K
Topics: Alzheimer Disease; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Dendrites; Disease Models, Animal; Hippocampus; Humans; Long-Term Potentiation; Memantine; Memory; Memory Disorders; Mice; Mice, Transgenic; Neurons; Phosphorylation; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyramidal Cells; Synapses; Temporal Lobe | 2018 |
Effect of co-administration of memantine and sertraline on the antidepressant-like activity and brain-derived neurotrophic factor (BDNF) levels in the rat brain.
Topics: Animals; Antidepressive Agents; Brain; Brain-Derived Neurotrophic Factor; Depressive Disorder; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Male; Memantine; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sertraline | 2017 |
Glioprotection of Retinal Astrocytes After Intravitreal Administration of Memantine in the Mouse Optic Nerve Crush Model.
Topics: Animals; Astrocytes; Disease Models, Animal; Glial Fibrillary Acidic Protein; Intravitreal Injections; Memantine; Mice, Inbred BALB C; Nerve Crush; Neuroglia; Neuroprotection; Observer Variation; Optic Nerve; Retina | 2017 |
NMDA receptor blockade with memantine attenuates white matter injury in a rat model of periventricular leukomalacia.
Topics: Animals; Animals, Newborn; Antigens, Differentiation; Biomarkers; Brain; Disease Models, Animal; Excitatory Amino Acid Antagonists; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Leukomalacia, Periventricular; Male; Memantine; Myelin Basic Protein; Nerve Fibers, Myelinated; Oligodendroglia; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Wallerian Degeneration | 2008 |
Memantine prevents the cognitive impairment induced by 3,4-methylenedioxymethamphetamine in rats.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Cognition; Cognition Disorders; Discrimination, Psychological; Disease Models, Animal; Excitatory Amino Acid Antagonists; Exploratory Behavior; Male; Maze Learning; Memantine; Mice; Motor Activity; Nicotinic Antagonists; Rats; Rats, Long-Evans; Recognition, Psychology; Time Factors | 2008 |
Acute liver failure-induced death of rats is delayed or prevented by blocking NMDA receptors in brain.
Topics: Ammonia; Animals; Brain; Disease Models, Animal; Disease Progression; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Galactosamine; Hepatic Encephalopathy; Hyperammonemia; Infusion Pumps, Implantable; Liver Failure, Acute; Male; Memantine; Microdialysis; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Severity of Illness Index; Time Factors | 2008 |
Memantine leads to behavioral improvement and amyloid reduction in Alzheimer's-disease-model transgenic mice shown as by micromagnetic resonance imaging.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Exploratory Behavior; Magnetic Resonance Imaging; Memantine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Recognition, Psychology | 2008 |
[Pathogenetic therapy of spasticity].
Topics: Adult; Aged; Animals; Cerebral Palsy; Child; Controlled Clinical Trials as Topic; Dantrolene; Disease Models, Animal; Dopamine Agents; Humans; Memantine; Middle Aged; Multiple Sclerosis; Muscle Hypotonia; Muscle Relaxants, Central; Muscle Spasticity; Muscle Tonus; Myofascial Pain Syndromes; Neuromuscular Agents; Rats | 2008 |
The effect of N-methyl-D-aspartate receptor antagonist (memantine) on esophageal and gastric smooth muscle: functional investigation in a rat hydrocephalus model.
Topics: Animals; Disease Models, Animal; Esophagus; Hydrocephalus; Memantine; Muscle Contraction; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stomach | 2008 |
Memantine protects against secondary neuronal degeneration in lateral geniculate nucleus and superior colliculus after retinal damage in mice.
Topics: Animals; Cell Death; Disease Models, Animal; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Follow-Up Studies; Geniculate Bodies; Male; Memantine; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neuroprotective Agents; Retina; Retinal Diseases; Retinal Ganglion Cells; Superior Colliculi; Visual Pathways | 2008 |
Augmentation of nitrite therapy in cerebral ischemia by NMDA receptor inhibition.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Male; Memantine; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Nitrite; Stroke | 2009 |
Antinociceptive effects of chronic administration of uncompetitive NMDA receptor antagonists in a rat model of diabetic neuropathic pain.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Cyclopentanes; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Memantine; Pain; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Streptozocin; Time Factors | 2009 |
Neuroprotective effect of memantine combined with topiramate in hypoxic-ischemic brain injury.
Topics: Animals; Animals, Newborn; Anticonvulsants; Apoptosis; Brain; Brain Infarction; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; Fructose; Glutamic Acid; Hypoxia-Ischemia, Brain; In Situ Nick-End Labeling; Male; Memantine; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Topiramate; Treatment Outcome | 2009 |
Accuracy of hippocampal network activity is disrupted by neuroinflammation: rescue by memantine.
Topics: Animals; Brain Mapping; Cells, Cultured; Chronic Disease; Cytoskeletal Proteins; Disease Models, Animal; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Exploratory Behavior; Gene Expression; Genes, Immediate-Early; Hippocampus; In Situ Hybridization, Fluorescence; Lipopolysaccharides; Male; Memantine; Microglia; Nerve Net; Nerve Tissue Proteins; Neurogenic Inflammation; Neurons; Rats; Rats, Inbred F344; Receptors, N-Methyl-D-Aspartate; RNA, Messenger | 2009 |
The combined effects of memantine and fluoxetine on an animal model of obsessive compulsive disorder.
Topics: Animals; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Fluoxetine; Male; Memantine; Mice; Obsessive-Compulsive Disorder; p-Methoxy-N-methylphenethylamine; Receptors, N-Methyl-D-Aspartate | 2009 |
Protection of DFP-induced oxidative damage and neurodegeneration by antioxidants and NMDA receptor antagonist.
Topics: Animals; Antioxidants; Biomarkers; Brain; Cholinesterase Inhibitors; Cyclic N-Oxides; Disease Models, Animal; Excitatory Amino Acid Antagonists; Injections, Intraperitoneal; Isoflurophate; Lipid Peroxidation; Male; Memantine; Neurodegenerative Diseases; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Time Factors; Vitamin A | 2009 |
Increased expression of PAD2 after repeated intracerebroventricular infusions of soluble Abeta(25-35) in the Alzheimer's disease model rat brain: effect of memantine.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; CD11b Antigen; Disease Models, Animal; Hydrolases; Immunohistochemistry; Infusions, Parenteral; Male; Memantine; Peptide Fragments; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminases; Rats; Rats, Wistar; Solubility | 2009 |
Effect of memantine on the levels of neuropeptides and microglial cells in the brain regions of rats with neuropathic pain.
Topics: Analgesics; Animals; Brain; CD11 Antigens; Disease Models, Animal; Excitatory Amino Acid Antagonists; Hyperalgesia; Hypothalamus; Male; Memantine; Microglia; Neuralgia; Neuropeptides; Periaqueductal Gray; Peripheral Nervous System Diseases; Rats; Rats, Wistar; Sciatic Neuropathy; Somatostatin; Substance P | 2009 |
Effects of memantine on soluble Alphabeta(25-35)-induced changes in peptidergic and glial cells in Alzheimer's disease model rat brain regions.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Biomarkers; Brain; CD11 Antigens; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Gliosis; Hippocampus; Male; Memantine; Nerve Degeneration; Neuroglia; Neuropeptides; Nitric Oxide Synthase Type II; Oxidative Stress; Peptide Fragments; Peptide Hydrolases; Rats; Rats, Wistar; Somatostatin; Substance P | 2009 |
Model of methadone-induced hyperalgesia in rats and effect of memantine.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Hyperalgesia; Male; Memantine; Methadone; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2010 |
Okadaic acid (ICV) induced memory impairment in rats: a suitable experimental model to test anti-dementia activity.
Topics: Animals; Brain; Calcium Signaling; Cholinesterase Inhibitors; Dementia; Disease Models, Animal; Donepezil; Drug Evaluation, Preclinical; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutathione; Indans; Injections, Intraventricular; Male; Malondialdehyde; Maze Learning; Memantine; Memory; Memory Disorders; Neuropsychological Tests; Nitrites; Okadaic Acid; Oxidative Stress; Piperidines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Treatment Outcome | 2010 |
Memantine: "hypothesis testing" not "disease modifying" in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid; Animals; Antiparkinson Agents; Clinical Trials as Topic; Concept Formation; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Memantine; Mice; Mice, Transgenic; Species Specificity | 2010 |
Memantine improves cognition and reduces Alzheimer's-like neuropathology in transgenic mice.
Topics: Age Factors; Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antiparkinson Agents; Cognition; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Male; Memantine; Mice; Mice, Transgenic; Phosphorylation; Protein Kinases; Protein Multimerization; tau Proteins | 2010 |
Regulation of Kv2.1 phosphorylation in an animal model of anoxia.
Topics: Animals; Brain; Brain Chemistry; Cell Survival; Disease Models, Animal; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Homeostasis; Hypoxia, Brain; Male; Memantine; Mice; Mice, Inbred ICR; Nerve Degeneration; Neurons; Phosphorylation; Shab Potassium Channels; Stress, Physiological; Time Factors | 2010 |
Folic Acid potentiates the effect of memantine on spatial learning and neuronal protection in an Alzheimer's disease transgenic model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Avoidance Learning; Disease Models, Animal; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Antagonists; Folic Acid; Gene Expression Profiling; Humans; Maze Learning; Memantine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neurons; Oligonucleotide Array Sequence Analysis; Peptide Fragments; Reaction Time; Spatial Behavior; Time Factors; Up-Regulation; Vitamin B Complex | 2010 |
Effects of long-term memantine on memory and neuropathology in Ts65Dn mice, a model for Down syndrome.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Cholinergic Fibers; Chromosomes, Mammalian; Disease Models, Animal; Down Syndrome; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Male; Maze Learning; Memantine; Memory Disorders; Mice; Mice, Mutant Strains; Motor Activity; Nerve Degeneration; Recognition, Psychology; Trisomy | 2011 |
Intracisternal administration of NR2 antagonists attenuates facial formalin-induced nociceptive behavior in rats.
Topics: Animals; Behavior, Animal; Cisterna Magna; Disease Models, Animal; Excitatory Amino Acid Antagonists; Facial Pain; Formaldehyde; Injections; Injections, Subcutaneous; Kynurenic Acid; Male; Memantine; Motor Activity; Nociceptors; Phenols; Piperazines; Piperidines; Pruritus; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Time Factors; Vibrissae | 2010 |
Memantine normalizes several phenotypic features in the Ts65Dn mouse model of Down syndrome.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Antiparkinson Agents; Behavior, Animal; Cues; Disease Models, Animal; Down Syndrome; Exploratory Behavior; Gait Disorders, Neurologic; Gene Expression Regulation; Humans; Maze Learning; Memantine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phenotype; Psychomotor Performance; Reaction Time; Rotarod Performance Test; Space Perception; Vesicular Glutamate Transport Protein 1 | 2010 |
Memantine exacerbates myoclonic jerks in a rat model of posthypoxic myoclonus.
Topics: Animals; Cerebellum; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hypoxia, Brain; Male; Memantine; Myoclonus; Nerve Degeneration; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2010 |
Effect of memantine on overactive detrusor in rats with spinal cord injury.
Topics: Animals; Disease Models, Animal; Female; Humans; Injections, Intraperitoneal; Male; Memantine; Rats; Rats, Wistar; Spinal Cord Injuries; Urinary Bladder, Overactive | 2010 |
The basal forebrain cholinergic system in aging and dementia. Rescuing cholinergic neurons from neurotoxic amyloid-β42 with memantine.
Topics: Aging; Amyloid beta-Peptides; Animals; Attention; Avoidance Learning; Cholinergic Fibers; Dementia; Disease Models, Animal; Humans; Male; Memantine; Microglia; Nerve Degeneration; Peptide Fragments; Prosencephalon; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2011 |
Memantine reduces consumption of highly palatable food in a rat model of binge eating.
Topics: Animals; Binge-Eating Disorder; Dietary Fats; Disease Models, Animal; Eating; Feeding Behavior; Humans; Male; Memantine; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate | 2011 |
Profile: Nicholas Dodman. Can dogs behaving badly suggest a new way to treat OCD?
Topics: Animals; Behavior, Animal; Cadherins; Compulsive Behavior; Disease Models, Animal; Dog Diseases; Dogs; Excitatory Amino Acid Antagonists; History, 20th Century; History, 21st Century; Humans; Memantine; Obsessive-Compulsive Disorder; Stereotyped Behavior; United States; Veterinary Medicine | 2010 |
Memantine-induced brain activation as a model for the rapid screening of potential novel antipsychotic compounds: exemplified by activity of an mGlu2/3 receptor agonist.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Autoradiography; Biological Transport; Brain; Bridged Bicyclo Compounds, Heterocyclic; Carbon Radioisotopes; Cyclic S-Oxides; Deoxyglucose; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; High-Throughput Screening Assays; Ketamine; Male; Memantine; Mice; Mice, Inbred C57BL; Receptors, Metabotropic Glutamate; Reproducibility of Results; Schizophrenia | 2011 |
Memantine reduces mania-like symptoms in animal models.
Topics: Action Potentials; Animals; Antimanic Agents; Bipolar Disorder; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Exploratory Behavior; Hippocampus; In Vitro Techniques; Lithium Chloride; Male; Memantine; Ouabain; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Time Factors | 2011 |
Subchronic memantine administration on spatial learning, exploratory activity, and nest-building in an APP/PS1 mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Avoidance Learning; Discrimination, Psychological; Disease Models, Animal; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Male; Maze Learning; Memantine; Mice; Mice, Neurologic Mutants; Nesting Behavior; Presenilin-1 | 2011 |
Synaptic plasticity deficits in an experimental model of rett syndrome: long-term potentiation saturation and its pharmacological reversal.
Topics: Animals; Blotting, Western; Brain; Disease Models, Animal; Dopamine Agents; Immunohistochemistry; Long-Term Potentiation; Male; Memantine; Methyl-CpG-Binding Protein 2; Mice; Neuronal Plasticity; Patch-Clamp Techniques; Rett Syndrome | 2011 |
Possible antidepressant effects and mechanisms of memantine in behaviors and synaptic plasticity of a depression rat model.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depressive Disorder; Disease Models, Animal; Excitatory Amino Acid Antagonists; Male; Memantine; Neuronal Plasticity; Prefrontal Cortex; Rats; Rats, Wistar; Stress, Psychological | 2011 |
An immunohistochemical analysis of the neuroprotective effects of memantine, hyperbaric oxygen therapy, and brimonidine after acute ischemia reperfusion injury.
Topics: Animals; Brimonidine Tartrate; Cell Count; Disease Models, Animal; Hyperbaric Oxygenation; Immunohistochemistry; Injections, Intravenous; Memantine; Neuroprotective Agents; Ophthalmic Solutions; Quinoxalines; Rats; Rats, Wistar; Reperfusion Injury; Retina; Retinal Ganglion Cells | 2011 |
Memantine prevents aluminum-induced cognitive deficit in rats.
Topics: Aluminum; Analysis of Variance; Animals; Body Weight; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Escape Reaction; Excitatory Amino Acid Antagonists; Exploratory Behavior; Male; Maze Learning; Memantine; Rats; Rats, Wistar; Rotarod Performance Test; Time Factors | 2011 |
Calpain activation is involved in acute manganese neurotoxicity in the rat striatum in vivo.
Topics: Analysis of Variance; Animals; Calpain; Caspase 3; Cell Death; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fluoresceins; Globus Pallidus; Male; Manganese; Manganese Poisoning; Memantine; Nerve Tissue Proteins; Neurons; Organic Chemicals; Rats; Rats, Wistar; Time Factors | 2012 |
Lithium, phenserine, memantine and pioglitazone reverse memory deficit and restore phospho-GSK3β decreased in hippocampus in intracerebroventricular streptozotocin induced memory deficit model.
Topics: Animals; Conditioning, Classical; Disease Models, Animal; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Hippocampus; Hypoglycemic Agents; Infusions, Intraventricular; Lithium; Male; Memantine; Memory Disorders; Neuroprotective Agents; Physostigmine; Pioglitazone; Prefrontal Cortex; Rats; Rats, Wistar; Statistics, Nonparametric; Streptozocin; Thiazolidinediones | 2011 |
Exaggerated NMDA mediated LTD in a mouse model of Down syndrome and pharmacological rescuing by memantine.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Down Syndrome; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Memantine; Methoxyhydroxyphenylglycol; Mice; Mice, Mutant Strains; N-Methylaspartate; Time Factors; Trisomy | 2011 |
Cell proliferation in the hippocampus and in the heart is modified by exposure to repeated stress and treatment with memantine.
Topics: Aldosterone; Analysis of Variance; Animals; Body Weight; Bromodeoxyuridine; Cell Count; Cell Proliferation; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Antagonists; Exploratory Behavior; Hippocampus; Male; Memantine; Myocardium; Radioimmunoassay; Rats; Rats, Wistar; Renin; Stress, Psychological; Time Factors | 2012 |
Effects of the uncompetitive NMDA receptor antagonist memantine on spatial memory in medial septal lesioned rats.
Topics: Alzheimer Disease; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Male; Maze Learning; Memantine; Memory; Placebos; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2011 |
Synergistic effects of antidementia drugs on spatial learning and recall in the APP23 transgenic mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; Drug Synergism; Excitatory Amino Acid Antagonists; Indans; Male; Maze Learning; Memantine; Memory; Mice; Mice, Transgenic; Motor Activity; Piperidines; Rest; Spatial Behavior | 2012 |
Structure/function studies and the effects of memantine in monkeys with experimental glaucoma.
Topics: Animals; Axons; Case-Control Studies; Disease Models, Animal; Evoked Potentials, Visual; Excitatory Amino Acid Antagonists; Female; Glaucoma; Intraocular Pressure; Macaca fascicularis; Male; Memantine; Optic Nerve; Photography; Scanning Laser Polarimetry | 2012 |
False recognition in a mouse model of Alzheimer's disease: rescue with sensory restriction and memantine.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Electric Stimulation; Long-Term Synaptic Depression; Memantine; Mice; Mice, Transgenic; Plaque, Amyloid; Recognition, Psychology; Sensory Deprivation; Temporal Lobe | 2012 |
Pretreatment with memantine prevents Alzheimer-like alterations induced by intrahippocampal okadaic acid administration in rats.
Topics: Alzheimer Disease; Animals; Carcinogens; Chromatography, High Pressure Liquid; Cyclin-Dependent Kinase 5; Disease Models, Animal; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Exploratory Behavior; Glutamic Acid; Hippocampus; Locomotion; Male; Maze Learning; Memantine; Okadaic Acid; Rats; Rats, Wistar; Signal Transduction; Statistics as Topic; tau Proteins | 2012 |
The therapeutic effect of memantine through the stimulation of synapse formation and dendritic spine maturation in autism and fragile X syndrome.
Topics: Animals; Autistic Disorder; Cell Adhesion; Cell Movement; Cells, Cultured; Cerebellum; Dendritic Spines; Disease Models, Animal; Fragile X Mental Retardation Protein; Fragile X Syndrome; Memantine; Mice; Mice, Inbred C57BL; Mice, Knockout; Synapses | 2012 |
Mitigation of augmented extrasynaptic NMDAR signaling and apoptosis in cortico-striatal co-cultures from Huntington's disease mice.
Topics: Animals; Apoptosis; Cerebral Cortex; Coculture Techniques; Corpus Striatum; Disease Models, Animal; Excitatory Amino Acid Antagonists; Huntington Disease; Memantine; Mice; Mice, Transgenic; Neurons; Piperidines; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2012 |
Age-dependent therapeutic effect of memantine in a mouse model of juvenile Batten disease.
Topics: Aging; Animals; Cerebral Cortex; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Drug Resistance; Excitatory Amino Acid Antagonists; Female; Male; Memantine; Membrane Glycoproteins; Mice; Mice, 129 Strain; Mice, Knockout; Molecular Chaperones; Molecular Targeted Therapy; Motor Skills; Nerve Tissue Proteins; Neuronal Ceroid-Lipofuscinoses; Neurons; Organ Specificity; Receptors, N-Methyl-D-Aspartate | 2012 |
Memantine and dizocilpine interactions with antinociceptive or discriminative stimulus effects of morphine in rats after acute or chronic treatment with morphine.
Topics: Analgesics, Opioid; Animals; Discrimination Learning; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Tolerance; Excitatory Amino Acid Antagonists; Male; Memantine; Morphine; Pain; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Reinforcement Schedule | 2013 |
A study on neuroinflammation and NMDA receptor function in STZ (ICV) induced memory impaired rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalitis; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Ibuprofen; Injections, Intraventricular; Male; Maze Learning; Memantine; Memory Disorders; Motor Activity; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Statistics, Nonparametric; Streptozocin | 2013 |
Synergistic effects of galantamine and memantine in attenuating scopolamine-induced amnesia in mice.
Topics: Amnesia; Animals; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Galantamine; Male; Memantine; Mice; Mice, Inbred Strains; Recognition, Psychology; Scopolamine | 2012 |
The smallest stroke: occlusion of one penetrating vessel leads to infarction and a cognitive deficit.
Topics: Animals; Brain Infarction; Brain Mapping; Calcium; Cognition Disorders; Disease Models, Animal; Dizocilpine Maleate; Glial Fibrillary Acidic Protein; Humans; Imaging, Three-Dimensional; Infarction, Middle Cerebral Artery; Male; Memantine; Microscopy, Confocal; Microvessels; Models, Biological; Neural Pathways; Neuroprotective Agents; Phosphopyruvate Hydratase; Psychomotor Performance; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Somatosensory Cortex; Vibrissae | 2013 |
Characterization of cognitive deficits in a transgenic mouse model of Alzheimer's disease and effects of donepezil and memantine.
Topics: Alzheimer Disease; Animals; Brain; Cholinesterase Inhibitors; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Donepezil; Female; Indans; Maze Learning; Memantine; Memory; Memory Disorders; Mice; Mice, Transgenic; Nootropic Agents; Piperidines; Receptors, AMPA | 2013 |
Piperine decreases pilocarpine-induced convulsions by GABAergic mechanisms.
Topics: Alkaloids; Amino Acids; Animals; Anticonvulsants; Antioxidants; Atropine; Benzodioxoles; Biogenic Monoamines; Brain; Diazepam; Disease Models, Animal; Epilepsy; Flumazenil; gamma-Aminobutyric Acid; Humans; Male; Memantine; Mice; Nimodipine; Nitrites; Pilocarpine; Piperidines; Polyunsaturated Alkamides; Seizures; Tumor Necrosis Factor-alpha | 2013 |
Effects of memantine and melatonin on signal transduction pathways vascular leakage and brain injury after focal cerebral ischemia in mice.
Topics: Analysis of Variance; Animals; Cerebral Cortex; Cerebral Infarction; Corpus Striatum; Disease Models, Animal; DNA Fragmentation; Immunoglobulin G; Infarction, Middle Cerebral Artery; Laser-Doppler Flowmetry; Male; MAP Kinase Signaling System; Melatonin; Memantine; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Phosphorylation; Signal Transduction | 2013 |
Effects of anti-glaucoma medications on ganglion cell survival: the DBA/2J mouse model.
Topics: Aging; Analysis of Variance; Animals; Antihypertensive Agents; Brimonidine Tartrate; Cell Survival; Disease Models, Animal; Glaucoma; Memantine; Mice; Mice, Inbred DBA; Quinoxalines; Retinal Ganglion Cells; Timolol | 2002 |
The ability of new non-competitive glutamate receptor blockers to weaken motor disorders in animals.
Topics: Animals; Ataxia; Behavior, Animal; Catalepsy; Diamines; Disease Models, Animal; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Haloperidol; Kainic Acid; Memantine; Mice; Mice, Inbred Strains; N-Methylaspartate; Quaternary Ammonium Compounds; Seizures; Structure-Activity Relationship; Time Factors | 2003 |
Neurochemical characteristics of the ventromedial hypothalamus in mediating the antiaversive effects of anxiolytics in different models of anxiety.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Apomorphine; Avoidance Learning; Biguanides; Brain Chemistry; Chlordiazepoxide; Clonidine; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Droperidol; Drug Interactions; GABA Agents; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Glutamic Acid; Male; Memantine; Mephenytoin; Microinjections; Pentylenetetrazole; Phentolamine; Picrotoxin; Piperazines; Propranolol; Pyrimidines; Rats; Serotonin; Sulpiride; Ventromedial Hypothalamic Nucleus; Yohimbine | 2003 |
Memantine, an NMDA antagonist, prevents the development of hyperthermia in an animal model for serotonin syndrome.
Topics: 5-Hydroxytryptophan; Animals; Body Temperature; Clorgyline; Disease Models, Animal; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Fever; Hypothalamus; Ketamine; Male; Memantine; Microdialysis; Norepinephrine; Rats; Rats, Wistar; Risperidone; Serotonin; Serotonin Antagonists; Serotonin Syndrome; Time Factors | 2004 |
Combination therapy in ischemic stroke: synergistic neuroprotective effects of memantine and clenbuterol.
Topics: Adrenergic beta-Agonists; Animals; Brain Ischemia; Cells, Cultured; Clenbuterol; Disease Models, Animal; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Glutamates; Hippocampus; Memantine; Mice; Neurons; Neuroprotective Agents; Rats; Rats, Inbred F344; Receptors, N-Methyl-D-Aspartate; Staurosporine; Stroke | 2004 |
The presence of the APP(swe) mutation in mice does not increase the vulnerability of cholinergic basal forebrain neurons to neuroinflammation.
Topics: Acetylcholine; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Choline O-Acetyltransferase; Cholinergic Fibers; Disease Models, Animal; Down-Regulation; Encephalitis; Genetic Predisposition to Disease; Gliosis; Humans; Male; Memantine; Mice; Mice, Transgenic; Mutation; Neurons; Neurotoxins; Prosencephalon; Receptors, N-Methyl-D-Aspartate; Tumor Necrosis Factor-alpha | 2004 |
Effect of gabapentin derivates on mechanical allodynia-like behaviour in a rat model of chronic sciatic constriction injury.
Topics: Amines; Animals; Chronic Disease; Cyclohexanecarboxylic Acids; Cyclohexanols; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Memantine; Pain; Pain Threshold; Pregabalin; Prodrugs; Rats; Sciatic Neuropathy; Structure-Activity Relationship; Venlafaxine Hydrochloride | 2004 |
Effect of memantine on the levels of glial cells, neuropeptides, and peptide-degrading enzymes in rat brain regions of ibotenic acid-treated alzheimer's disease model.
Topics: Alzheimer Disease; Animals; Blotting, Western; Brain; Disease Models, Animal; Dopamine Agents; Electrophoresis, Polyacrylamide Gel; Excitatory Amino Acid Agonists; Ibotenic Acid; Immunohistochemistry; Male; Memantine; Neuroglia; Neuropeptides; Peptide Hydrolases; Rats; Rats, Wistar | 2004 |
Efficacy and safety of memantine treatment for reduction of changes associated with experimental glaucoma in monkey, I: Functional measures.
Topics: Administration, Oral; Animals; Cell Count; Chronic Disease; Disease Models, Animal; Electroretinography; Evoked Potentials, Visual; Excitatory Amino Acid Antagonists; Glaucoma; Glutamic Acid; Intraocular Pressure; Macaca fascicularis; Memantine; Ocular Hypertension; Optic Nerve Diseases; Retina; Retinal Ganglion Cells; Safety; Treatment Outcome; Vitreous Body | 2004 |
Efficacy and safety of memantine treatment for reduction of changes associated with experimental glaucoma in monkey, II: Structural measures.
Topics: Administration, Oral; Animals; Cell Count; Cell Survival; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glaucoma; Intraocular Pressure; Macaca fascicularis; Memantine; Ocular Hypertension; Optic Disk; Optic Nerve Diseases; Retina; Retinal Ganglion Cells; Safety; Treatment Outcome | 2004 |
Symptomatic effect of donepezil, rivastigmine, galantamine and memantine on cognitive deficits in the APP23 model.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cholinesterase Inhibitors; Cognition; Disease Models, Animal; Donepezil; Dose-Response Relationship, Drug; Galantamine; Humans; Indans; Male; Memantine; Mice; Mice, Mutant Strains; Phenylcarbamates; Piperidines; Rivastigmine; Sensitivity and Specificity | 2005 |
19F and 1H MRI detection of amyloid beta plaques in vivo.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloidosis; Animals; Brain; Brain Chemistry; Cell Count; Disease Models, Animal; Dose-Response Relationship, Drug; Fluorescent Dyes; Humans; Imaging, Three-Dimensional; Immunohistochemistry; Magnetic Resonance Imaging; Memantine; Mice; Mice, Transgenic; Phosphopyruvate Hydratase; Plaque, Amyloid; Radionuclide Imaging; Staining and Labeling; Time Factors; Tritium | 2005 |
The effects of memantine on lipid peroxidation following closed-head trauma in rats.
Topics: Animals; Brain; Brain Injuries; Disease Models, Animal; Excitatory Amino Acid Antagonists; Head Injuries, Closed; Lipid Peroxidation; Male; Malondialdehyde; Memantine; Rats; Rats, Sprague-Dawley; Time Factors | 2005 |
Cognitive evaluation of disease-modifying efficacy of galantamine and memantine in the APP23 model.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Cholinesterase Inhibitors; Cognition; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Excitatory Amino Acid Antagonists; Galantamine; Humans; Maze Learning; Memantine; Mice; Mice, Transgenic; Motor Activity; Neuropsychological Tests; Random Allocation; Reaction Time; Time Factors | 2006 |
Memantine reduces hematoma expansion in experimental intracerebral hemorrhage, resulting in functional improvement.
Topics: Animals; Cerebral Hemorrhage; Disease Models, Animal; Gene Expression Regulation; Hematoma; Male; Matrix Metalloproteinases; Memantine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tissue Plasminogen Activator; Treatment Outcome; Urokinase-Type Plasminogen Activator | 2006 |
Memantine prolongs survival in an amyotrophic lateral sclerosis mouse model.
Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Humans; Immunohistochemistry; Memantine; Mice; Mice, Transgenic; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Superoxide Dismutase; Survival Analysis; Time Factors; Treatment Outcome | 2005 |
Evidence for the involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of memantine in mice.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Arginine; Cyclic GMP; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Immobility Response, Tonic; Male; Memantine; Mice; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Penicillamine; Piperazines; Purines; Sildenafil Citrate; Sulfones; Swimming | 2006 |
Memantine protects neurons from shrinkage in the lateral geniculate nucleus in experimental glaucoma.
Topics: Animals; Atrophy; Cell Count; Cytoprotection; Disease Models, Animal; Excitatory Amino Acid Antagonists; Geniculate Bodies; Glaucoma; Immunoenzyme Techniques; Intraocular Pressure; Macaca fascicularis; Memantine; Nerve Degeneration; Nerve Fibers; Neurons; Optic Nerve Diseases; Parvalbumins | 2006 |
Low doses of memantine disrupt memory in adult rats.
Topics: Alzheimer Disease; Animals; Antiparkinson Agents; Brain Edema; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; Hippocampus; Humans; Memantine; Memory; Memory Disorders; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 2006 |
Memantine, an uncompetitive low affinity NMDA open-channel antagonist improves clinical rating scores in a multiple infarct embolic stroke model in rabbits.
Topics: Animals; Brain Infarction; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Intracranial Embolism; Male; Memantine; Rabbits; Time Factors | 2006 |
Cognitive dysfunction induced by sequential injection of amyloid-beta and ibotenate into the bilateral hippocampus; protection by memantine and MK-801.
Topics: Amyloid beta-Peptides; Animals; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Ibotenic Acid; Male; Maze Learning; Memantine; Memory; Memory Disorders; Neurons; Neuroprotective Agents; Peptide Fragments; Rats; Rats, Inbred F344; Receptors, N-Methyl-D-Aspartate | 2006 |
Memantine reduces striatal cell death with decreasing calpain level in 3-nitropropionic model of Huntington's disease.
Topics: Animals; Apoptosis Regulatory Proteins; Calpain; Cell Death; Corpus Striatum; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Antagonists; Huntingtin Protein; Huntington Disease; Male; Memantine; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Nuclear Proteins; Peptide Fragments; Propionates; Rats; Rats, Sprague-Dawley | 2006 |
Memantine protects against LPS-induced neuroinflammation, restores behaviorally-induced gene expression and spatial learning in the rat.
Topics: Animals; Behavior, Animal; Cytoskeletal Proteins; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalitis; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Gliosis; Inflammation Mediators; Lipopolysaccharides; Male; Memantine; Memory; Memory Disorders; Microglia; Nerve Tissue Proteins; Neurodegenerative Diseases; Neuroprotective Agents; Rats; Rats, Inbred F344; Receptors, N-Methyl-D-Aspartate | 2006 |
Combined neuroprotective effects of celecoxib and memantine in experimental intracerebral hemorrhage.
Topics: Animals; Caspase 3; CD11b Antigen; Celecoxib; Cerebral Hemorrhage; Collagenases; Disease Models, Animal; Drug Therapy, Combination; Functional Laterality; In Situ Nick-End Labeling; Male; Memantine; Neuroprotective Agents; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides | 2007 |
NMDA receptor-mediated excitotoxicity contributes to the cerebral hypoxic injury of a rat model of posthypoxic myoclonus.
Topics: Animals; Brain Damage, Chronic; Cerebellum; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Hypoxia, Brain; Intralaminar Thalamic Nuclei; Male; Memantine; Myoclonus; Nerve Degeneration; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2007 |
Erythropoietin promotes survival of retinal ganglion cells in DBA/2J glaucoma mice.
Topics: Animals; Axons; Cell Survival; Disease Models, Animal; Erythropoietin; Fluorescent Antibody Technique, Indirect; Glaucoma; Intraocular Pressure; Memantine; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microscopy, Fluorescence; Neuroprotective Agents; Optic Nerve; Optic Nerve Diseases; Receptors, Erythropoietin; Recombinant Proteins; Retinal Ganglion Cells | 2007 |
Failure to improve the effect of thrombolysis by memantine in a rat embolic stroke model.
Topics: Animals; Disease Models, Animal; Fibrinolytic Agents; Male; Memantine; Rats; Rats, Wistar; Statistics, Nonparametric; Stroke; Tissue Plasminogen Activator; Treatment Failure | 2007 |
Acute injections of the NMDA receptor antagonist memantine rescue performance deficits of the Ts65Dn mouse model of Down syndrome on a fear conditioning test.
Topics: Age Factors; Analysis of Variance; Animals; Behavior, Animal; Conditioning, Psychological; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Down Syndrome; Excitatory Amino Acid Antagonists; Fear; Learning; Male; Memantine; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Mice, Transgenic; Motor Activity | 2008 |
Transient allodynia pain models in mice for early assessment of analgesic activity.
Topics: Adrenergic alpha-Antagonists; Amines; Amitriptyline; Analgesics; Animals; Clonidine; Cyclohexanecarboxylic Acids; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Intraperitoneal; Injections, Spinal; Male; Memantine; Mice; Mice, Inbred C57BL; Morphine; N-Methylaspartate; Pain; Peripheral Nervous System; Phenylephrine; Piperazines; Prostaglandin Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, N-Methyl-D-Aspartate; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Reproducibility of Results; Spinal Cord; Spinal Nerves; Time Factors | 2008 |
Expression of N-methyl-d-aspartate receptor 1 in rats with chronic ocular hypertension.
Topics: Analysis of Variance; Animals; Cell Death; Disease Models, Animal; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Intraocular Pressure; Male; Memantine; Ocular Hypertension; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; Stilbamidines; Time Factors | 2007 |
Memantine upregulates BDNF and prevents dopamine deficits in SIV-infected macaques: a novel pharmacological action of memantine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Dopamine; Excitatory Amino Acid Antagonists; Homovanillic Acid; Humans; Macaca mulatta; Memantine; Oligonucleotide Array Sequence Analysis; RNA, Messenger; Simian Acquired Immunodeficiency Syndrome; Up-Regulation; Viral Load | 2008 |
Memantine acts as a cholinergic stimulant in the mouse hippocampus.
Topics: Alzheimer Disease; Animals; Antiparkinson Agents; Central Nervous System Stimulants; Cholinergic Fibers; Cognition Disorders; Disease Models, Animal; Female; Hippocampus; Maze Learning; Memantine; Mice; Nerve Degeneration; Receptors, N-Methyl-D-Aspartate; Space Perception; Time Factors | 2007 |
Effects of memantine and MK-801 on ischemia in an experimental model of acute subdural hematoma.
Topics: Animals; Brain Edema; Brain Ischemia; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Functional Laterality; Hematoma, Subdural, Acute; Memantine; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric | 2008 |
Glutamate-mediated neuroplasticity in an animal model of self-injurious behaviour.
Topics: Animals; Behavior, Animal; Biogenic Monoamines; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Memantine; Neuronal Plasticity; Neurotransmitter Uptake Inhibitors; Pemoline; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Self-Injurious Behavior | 2008 |
Effects of memantine on neuronal structure and conditioned fear in the Tg2576 mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Axons; Behavior, Animal; Brain; Conditioning, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fear; Genotype; Memantine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Electron, Transmission; Neuroprotective Agents; Neurotoxins; Plaque, Amyloid; Synapses; Wallerian Degeneration | 2008 |
The clinically tested N-methyl-D-aspartate receptor antagonist memantine blocks and reverses thermal hyperalgesia in a rat model of painful mononeuropathy.
Topics: Animals; Disease Models, Animal; Hyperalgesia; Male; Memantine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors | 1995 |
Memantine, a noncompetitive NMDA receptor antagonist improves hyperammonemia-induced encephalopathy and acute hepatic encephalopathy in rats.
Topics: Ammonia; Animals; Body Water; Brain; Disease Models, Animal; Electroencephalography; Glutamic Acid; Hepatic Encephalopathy; Intracranial Pressure; Ischemia; Liver; Male; Memantine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1997 |
Memantine is neuroprotective in a rat model of pressure-induced retinal ischemia.
Topics: Animals; Cell Count; Chromatography, High Pressure Liquid; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Intraocular Pressure; Ischemia; Male; Memantine; N-Methylaspartate; Ocular Hypertension; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells; Retinal Vessels; Vitreous Body | 1998 |
Ethanol-reinforced behaviour in the rat: effects of uncompetitive NMDA receptor antagonist, memantine.
Topics: Alcohol Drinking; Alcoholism; Animals; Disease Models, Animal; Drinking; Eating; Ethanol; Excitatory Amino Acid Antagonists; Male; Memantine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Self Administration | 1998 |
Memantine for prevention of spinal cord injury in a rabbit model.
Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Evoked Potentials, Motor; Excitatory Amino Acid Antagonists; Memantine; Motor Neurons; Rabbits; Random Allocation; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Cord Injuries; Statistics, Nonparametric; Time Factors | 1999 |
[Glutamate receptor agonists and alcohol dependence. Preclinical findings].
Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Animals; Chronic Disease; Disease Models, Animal; Humans; Memantine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Secondary Prevention; Taurine | 1999 |
Neuroprotection by the NMDA receptor-associated open-channel blocker memantine in a photothrombotic model of cerebral focal ischemia in neonatal rat.
Topics: Animals; Animals, Newborn; Brain; Brain Ischemia; Cerebrovascular Disorders; Disease Models, Animal; Infarction; Light; Magnetic Resonance Imaging; Memantine; Neuroprotective Agents; Random Allocation; Rats; Rats, Long-Evans; Thrombosis | 1999 |
A word of caution in extrapolating the spinal cord protective effects of memantine obtained in a rabbit model under ketamine anesthesia.
Topics: Anesthetics, Dissociative; Animals; Blood-Brain Barrier; Body Temperature; Disease Models, Animal; Esophagus; Evoked Potentials, Motor; Excitatory Amino Acid Antagonists; Infusions, Intravenous; Ketamine; Memantine; Neuroprotective Agents; Rabbits; Rectum; Spinal Cord; Spinal Cord Ischemia; Time Factors | 1999 |
[Neuroprotective effect of N-methyl-D-aspartate receptor antagonists in an experimental glaucoma model in the rat].
Topics: Animals; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glaucoma; Male; Memantine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2000 |
[Neuroprotection. Bases and possibilities of a future clinical use].
Topics: Adrenergic alpha-Agonists; Animals; Apoptosis; Brimonidine Tartrate; Clinical Trials as Topic; Disease Models, Animal; Dopamine Agents; Eye Diseases; Forecasting; Glaucoma; Humans; Memantine; Neuroprotective Agents; Optic Neuritis; Quinoxalines; Retinal Diseases; Visual Fields | 2001 |
The role of neurochemical mechanisms of ventromedial hypothalamus in various models of anxiety in rats.
Topics: Adrenergic Agents; Animals; Anxiety; Apomorphine; Avoidance Learning; Disease Models, Animal; Dopamine; Dopamine Agents; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamus, Middle; Male; Memantine; Microinjections; Neurotransmitter Agents; Phenylephrine; Picrotoxin; Rats; Serotonin; Sulpiride; Yohimbine | 2001 |
[Prospects for neuroprotective glaucoma therapy].
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Apoptosis; Betaxolol; Brain-Derived Neurotrophic Factor; Brimonidine Tartrate; Calcium Channel Blockers; Disease Models, Animal; Dopamine Agents; Glaucoma; Glaucoma, Open-Angle; Haplorhini; Humans; Memantine; Neuroprotective Agents; Nimodipine; Nitric Oxide Synthase; Quinoxalines; Receptors, N-Methyl-D-Aspartate | 2001 |