memantine has been researched along with Cranial Nerve II Injuries in 3 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenytoin is a well-characterized sodium channel blocker in widespread use as an anticonvulsant." | 1.31 | Phenytoin blocks retinal ganglion cell death after partial optic nerve crush. ( Naskar, R; Quinto, K; Romann, I; Schuettauf, F; Zurakowski, D, 2002) |
| "Chronic ocular hypertension was attained by laser photocoagulation of episcleral and limbal veins." | 1.31 | Neuroprotective effect of memantine in different retinal injury models in rats. ( Ruiz, G; Schwartz, M; Wheeler, LA; WoldeMussie, E; Yoles, E, 2002) |
| " We therefore explored whether a glutamate congener was toxic if applied directly within the optic nerve, or if toxicity depended upon an interaction at the cell body level." | 1.31 | Excitotoxicity can be mediated through an interaction within the optic nerve; activation of cell body NMDA receptors is not required. ( Dreyer, EB; McDermott, LM; Naskar, R; Quinto, KM; Schuettauf, F; Vorwerk, CK; Zurakowski, D, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Naskar, R | 2 |
| Quinto, K | 1 |
| Romann, I | 1 |
| Schuettauf, F | 2 |
| Zurakowski, D | 2 |
| WoldeMussie, E | 1 |
| Yoles, E | 1 |
| Schwartz, M | 1 |
| Ruiz, G | 1 |
| Wheeler, LA | 1 |
| Vorwerk, CK | 1 |
| McDermott, LM | 1 |
| Quinto, KM | 1 |
| Dreyer, EB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Cohort Study of Association Between Steady State Phenytoin Treatment and Better Clinical Parameters of Glaucoma[NCT00739154] | 200 participants (Anticipated) | Observational | 2008-11-30 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for memantine and Cranial Nerve II Injuries
| Article | Year |
|---|---|
Phenytoin blocks retinal ganglion cell death after partial optic nerve crush.
Topics: Analysis of Variance; Animals; Calcium; Cell Death; Cell Survival; Drug Therapy, Combination; Excita | 2002 |
Neuroprotective effect of memantine in different retinal injury models in rats.
Topics: Action Potentials; Animals; Cell Count; Cell Survival; Chronic Disease; Electrophysiology; Excitator | 2002 |
Excitotoxicity can be mediated through an interaction within the optic nerve; activation of cell body NMDA receptors is not required.
Topics: Animals; Axotomy; Cell Survival; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; | 2001 |