Page last updated: 2024-10-30

memantine and Cortical Lewy Body Disease

memantine has been researched along with Cortical Lewy Body Disease in 29 studies

Research Excerpts

ExcerptRelevanceReference
"To investigate the effect on survival of treatment with memantine in patients with dementia with Lewy bodies (DLB) and Parkinson's disease with dementia (PDD)."9.19Treatment effect of memantine on survival in dementia with Lewy bodies and Parkinson's disease with dementia: a prospective study. ( Aarsland, D; Ballard, C; Larsson, V; Londos, E; Minthon, L; Stubendorff, K, 2014)
"To investigate quality of life (QOL) and the effect of memantine treatment in patients with Lewy body dementias."9.15Quality of life and the effect of memantine in dementia with lewy bodies and Parkinson's disease dementia. ( Aarsland, D; Engedal, K; Larsson, V; Londos, E; Minthon, L; Wattmo, C, 2011)
"Previous studies have suggested that patients with Lewy-body-related dementias might benefit from treatment with the N-methyl D-aspartate receptor antagonist memantine, but further data are needed."9.14Memantine for patients with Parkinson's disease dementia or dementia with Lewy bodies: a randomised, double-blind, placebo-controlled trial. ( Bladström, A; Bonuccelli, U; Ceballos-Baumann, A; Destée, A; Emre, M; Jones, R; Kutzelnigg, A; Tolosa, E; Tsolaki, M; Zdravkovic, S, 2010)
"To report on a patient with Lewy body dementia who developed worsening of hallucinations with memantine withdrawal and significant improvement with reinitiation of the drug."8.89Visual hallucinations treated with the reinitiation of memantine in a patient with Lewy body dementia. ( Blaszczyk, AT; Mathys, ML; McCarrell, J; Sleeper, RB, 2013)
"Three patients with probable dementia with Lewy bodies (DLB) experienced worsening delusions and visual hallucinations as a result of memantine therapy."7.73Delusions and hallucinations in dementia with Lewy bodies: worsening with memantine. ( Josephs, KA; Ridha, BH; Rossor, MN, 2005)
"To investigate the effect on survival of treatment with memantine in patients with dementia with Lewy bodies (DLB) and Parkinson's disease with dementia (PDD)."5.19Treatment effect of memantine on survival in dementia with Lewy bodies and Parkinson's disease with dementia: a prospective study. ( Aarsland, D; Ballard, C; Larsson, V; Londos, E; Minthon, L; Stubendorff, K, 2014)
"To investigate quality of life (QOL) and the effect of memantine treatment in patients with Lewy body dementias."5.15Quality of life and the effect of memantine in dementia with lewy bodies and Parkinson's disease dementia. ( Aarsland, D; Engedal, K; Larsson, V; Londos, E; Minthon, L; Wattmo, C, 2011)
"Previous studies have suggested that patients with Lewy-body-related dementias might benefit from treatment with the N-methyl D-aspartate receptor antagonist memantine, but further data are needed."5.14Memantine for patients with Parkinson's disease dementia or dementia with Lewy bodies: a randomised, double-blind, placebo-controlled trial. ( Bladström, A; Bonuccelli, U; Ceballos-Baumann, A; Destée, A; Emre, M; Jones, R; Kutzelnigg, A; Tolosa, E; Tsolaki, M; Zdravkovic, S, 2010)
"To report on a patient with Lewy body dementia who developed worsening of hallucinations with memantine withdrawal and significant improvement with reinitiation of the drug."4.89Visual hallucinations treated with the reinitiation of memantine in a patient with Lewy body dementia. ( Blaszczyk, AT; Mathys, ML; McCarrell, J; Sleeper, RB, 2013)
"Three patients with probable dementia with Lewy bodies (DLB) experienced worsening delusions and visual hallucinations as a result of memantine therapy."3.73Delusions and hallucinations in dementia with Lewy bodies: worsening with memantine. ( Josephs, KA; Ridha, BH; Rossor, MN, 2005)
" After memantine was started he developed severe fluctuations in awareness, visual hallucinations, agitation, and worsened parkinsonism."3.73Exacerbation of Lewy bodies dementia due to memantine. ( Blazquez-Menes, B; Calatayud, MT; Menendez-Gonzalez, M, 2005)
"A randomised double-blind, placebo-controlled, 24-week three centre trial of memantine (20 mg/day) was conducted in which tests of attention (simple and choice reaction time) and word recognition (immediate and delayed) from the CDR System were administered prior to dosing and again at 12 and 24 weeks."2.80Memantine improves attention and episodic memory in Parkinson's disease dementia and dementia with Lewy bodies. ( Aarsland, D; Ballard, C; Londos, E; Wesnes, KA, 2015)
"Dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD) are common forms of dementia that substantially affect quality of life."2.74Memantine in patients with Parkinson's disease dementia or dementia with Lewy bodies: a double-blind, placebo-controlled, multicentre trial. ( Aarsland, D; Alves, G; Ballard, C; Bostrom, F; Kossakowski, K; Leroi, I; Londos, E; Minthon, L; Pozo-Rodriguez, F; Walker, Z, 2009)
" Patients were divided into 2 groups: 14 patients who received memantine in dosage 20 mg/d and 9 patients of a control group."2.73[Efficacy and safety of memantine in dementia with Lewy bodies]. ( Amosova, NA; Batukaeva, LA; Levin, OS; Smolentseva, IG, 2008)
" We selected global impression and cognitive function as primary efficacy outcomes, and dropouts and adverse events as safety outcomes."2.52Efficacy and safety of cholinesterase inhibitors and memantine in cognitive impairment in Parkinson's disease, Parkinson's disease dementia, and dementia with Lewy bodies: systematic review with meta-analysis and trial sequential analysis. ( Jiang, T; Meng, XF; Tan, CC; Tan, L; Tan, MS; Tang, SW; Wang, C; Wang, HF; Yu, JT, 2015)
"Dementia with Lewy bodies and Parkinson's disease with dementia should be treated with rivastigmine."1.35[Treatment of degenerative dementia disorders--who should be treated?]. ( Hasselbalch, SG; Kampmann, JP, 2009)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's14 (48.28)29.6817
2010's14 (48.28)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Giebel, C1
Cations, M1
Draper, B1
Komuravelli, A1
Hausner, L1
Frölich, L1
Rodda, J1
Carter, J1
Matsunaga, S1
Kishi, T1
Iwata, N1
Wesnes, KA1
Aarsland, D8
Ballard, C7
Londos, E6
Wang, HF1
Yu, JT1
Tang, SW1
Jiang, T1
Tan, CC1
Meng, XF1
Wang, C1
Tan, MS1
Tan, L1
Stubendorff, K1
Larsson, V3
Minthon, L5
Levin, OS2
Batukaeva, LA2
Smolentseva, IG2
Amosova, NA2
Hasselbalch, SG1
Kampmann, JP1
Emre, M2
Walker, Z1
Bostrom, F1
Alves, G1
Kossakowski, K1
Leroi, I1
Pozo-Rodriguez, F1
Johansson, C1
Hansson, O1
Palmqvist, S1
Tsolaki, M1
Bonuccelli, U1
Destée, A1
Tolosa, E1
Kutzelnigg, A1
Ceballos-Baumann, A1
Zdravkovic, S1
Bladström, A1
Jones, R2
O'Brien, JT1
Burns, A2
Engedal, K1
Wattmo, C1
Rongve, A1
Broadstock, M1
Svenningsson, P1
Mathys, ML1
McCarrell, J1
Sleeper, RB1
Blaszczyk, AT1
Diehl, RR1
Ridha, BH1
Josephs, KA1
Rossor, MN1
Sabbagh, MN1
Hake, AM1
Ahmed, S1
Farlow, MR1
Menendez-Gonzalez, M1
Calatayud, MT1
Blazquez-Menes, B1
Henriksen, AL1
St Dennis, C1
Setter, SM1
Tran, JT1
Johannsen, P1
O'Brien, J1
Auriacombe, S1
Broich, K1
Bullock, R1
Feldman, H1
Ford, G1
Knapp, M1
McCaddon, A1
Iliffe, S1
Jacova, C1
Lennon, S1
McKeith, I1
Orgogozo, JM1
Purandare, N1
Richardson, M1
Ritchie, C1
Thomas, A1
Warner, J1
Wilcock, G1
Wilkinson, D1
Gallini, A1
Sommet, A1
Salandini, AM1
Veyssière, P1
Montastruc, JL2
Alisky, JM1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pilot Study of Memantine for Enhanced Stroke Recovery[NCT02144584]Early Phase 120 participants (Anticipated)Interventional2014-01-31Active, not recruiting
A Randomised, Double-blind, Placebo-controlled, 6-month Study of the Efficacy and Safety of Memantine in Patients With Parkinson's Disease Dementia or Dementia With Lewy Bodies[NCT00855686]Phase 4199 participants (Actual)Interventional2007-01-31Completed
The Effect of High Frequency Repetitive Transcranial Magnetic Stimulation on Cognitive Impairment in Parkinson's Disease[NCT03879551]30 participants (Actual)Interventional2019-03-15Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

10 reviews available for memantine and Cortical Lewy Body Disease

ArticleYear
[Cholesterol inhibitor and memantine in symptomatic dementia therapy].
    Praxis, 2013, Feb-27, Volume: 102, Issue:5

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cooperative Behavior; Dementi

2013
Memantine for Lewy body disorders: systematic review and meta-analysis.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2015, Volume: 23, Issue:4

    Topics: Excitatory Amino Acid Antagonists; Humans; Lewy Body Disease; Memantine; Patient Dropouts

2015
Efficacy and safety of cholinesterase inhibitors and memantine in cognitive impairment in Parkinson's disease, Parkinson's disease dementia, and dementia with Lewy bodies: systematic review with meta-analysis and trial sequential analysis.
    Journal of neurology, neurosurgery, and psychiatry, 2015, Volume: 86, Issue:2

    Topics: Antiparkinson Agents; Cholinesterase Inhibitors; Cognition Disorders; Humans; Lewy Body Disease; Mem

2015
Cognitive impairment in Parkinson's disease and dementia with Lewy bodies.
    Parkinsonism & related disorders, 2016, Volume: 22 Suppl 1

    Topics: Animals; Cholinesterase Inhibitors; Cognition Disorders; Humans; Lewy Body Disease; Memantine; Parki

2016
Clinical trials of dementia with Lewy bodies and Parkinson's disease dementia.
    Current neurology and neuroscience reports, 2012, Volume: 12, Issue:5

    Topics: Cholinesterase Inhibitors; Clinical Trials as Topic; Dementia; Humans; Lewy Body Disease; Memantine;

2012
Visual hallucinations treated with the reinitiation of memantine in a patient with Lewy body dementia.
    The Annals of pharmacotherapy, 2013, Volume: 47, Issue:2

    Topics: Aged; Dementia; Hallucinations; Humans; Lewy Body Disease; Male; Memantine; Nootropic Agents; Treatm

2013
[Dementia].
    Fortschritte der Neurologie-Psychiatrie, 2003, Volume: 71, Issue:11

    Topics: Activities of Daily Living; Aged; Alzheimer Disease; Cholinesterase Inhibitors; Cognition Disorders;

2003
Dementia with lewy bodies: therapeutic opportunities and pitfalls.
    The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists, 2006, Volume: 21, Issue:7

    Topics: Antiparkinson Agents; Antipsychotic Agents; Cholinesterase Inhibitors; Humans; Lewy Body Disease; Me

2006
[Medical treatment of Alzheimer's disease].
    Ugeskrift for laeger, 2006, Oct-02, Volume: 168, Issue:40

    Topics: Activities of Daily Living; Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials as Topic;

2006
Clinical practice with anti-dementia drugs: a consensus statement from British Association for Psychopharmacology.
    Journal of psychopharmacology (Oxford, England), 2006, Volume: 20, Issue:6

    Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Combined Modality Therapy; Consensus Development

2006

Trials

9 trials available for memantine and Cortical Lewy Body Disease

ArticleYear
Memantine improves attention and episodic memory in Parkinson's disease dementia and dementia with Lewy bodies.
    International journal of geriatric psychiatry, 2015, Volume: 30, Issue:1

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Antiparkinson Agents; Attention; Cognition; Double-Bl

2015
Treatment effect of memantine on survival in dementia with Lewy bodies and Parkinson's disease with dementia: a prospective study.
    BMJ open, 2014, Jul-03, Volume: 4, Issue:7

    Topics: Aged; Antiparkinson Agents; Dementia; Double-Blind Method; Female; Humans; Lewy Body Disease; Male;

2014
[Efficacy and safety of memantine in dementia with Lewy bodies].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2008, Volume: 108, Issue:5

    Topics: Aged; Antiparkinson Agents; Cognition; Dose-Response Relationship, Drug; Female; Follow-Up Studies;

2008
Efficacy and safety of memantine in Lewy body dementia.
    Neuroscience and behavioral physiology, 2009, Volume: 39, Issue:6

    Topics: Aged; Antiparkinson Agents; Cognition; Dose-Response Relationship, Drug; Female; Follow-Up Studies;

2009
Memantine in patients with Parkinson's disease dementia or dementia with Lewy bodies: a double-blind, placebo-controlled, multicentre trial.
    The Lancet. Neurology, 2009, Volume: 8, Issue:7

    Topics: Aged; Aged, 80 and over; Brain; Cognition; Cognition Disorders; Double-Blind Method; Excitatory Amin

2009
Efficacy of memantine in PDD and DLB: an extension study including washout and open-label treatment.
    International journal of geriatric psychiatry, 2011, Volume: 26, Issue:2

    Topics: Aged; Aged, 80 and over; Dopamine Agents; Double-Blind Method; Female; Humans; Lewy Body Disease; Ma

2011
Memantine for patients with Parkinson's disease dementia or dementia with Lewy bodies: a randomised, double-blind, placebo-controlled trial.
    The Lancet. Neurology, 2010, Volume: 9, Issue:10

    Topics: Accidental Falls; Aged; Aged, 80 and over; Dementia; Double-Blind Method; Europe; Female; Humans; In

2010
Memantine for patients with Parkinson's disease dementia or dementia with Lewy bodies: a randomised, double-blind, placebo-controlled trial.
    The Lancet. Neurology, 2010, Volume: 9, Issue:10

    Topics: Accidental Falls; Aged; Aged, 80 and over; Dementia; Double-Blind Method; Europe; Female; Humans; In

2010
Memantine for patients with Parkinson's disease dementia or dementia with Lewy bodies: a randomised, double-blind, placebo-controlled trial.
    The Lancet. Neurology, 2010, Volume: 9, Issue:10

    Topics: Accidental Falls; Aged; Aged, 80 and over; Dementia; Double-Blind Method; Europe; Female; Humans; In

2010
Memantine for patients with Parkinson's disease dementia or dementia with Lewy bodies: a randomised, double-blind, placebo-controlled trial.
    The Lancet. Neurology, 2010, Volume: 9, Issue:10

    Topics: Accidental Falls; Aged; Aged, 80 and over; Dementia; Double-Blind Method; Europe; Female; Humans; In

2010
The effect of memantine on sleep behaviour in dementia with Lewy bodies and Parkinson's disease dementia.
    International journal of geriatric psychiatry, 2010, Volume: 25, Issue:10

    Topics: Aged; Aged, 80 and over; Dopamine Agents; Female; Humans; Lewy Body Disease; Male; Memantine; Outcom

2010
Quality of life and the effect of memantine in dementia with lewy bodies and Parkinson's disease dementia.
    Dementia and geriatric cognitive disorders, 2011, Volume: 32, Issue:4

    Topics: Aged; Antiparkinson Agents; Antipsychotic Agents; Dementia; Diagnostic and Statistical Manual of Men

2011

Other Studies

10 other studies available for memantine and Cortical Lewy Body Disease

ArticleYear
Ethnic disparities in the uptake of anti-dementia medication in young and late-onset dementia.
    International psychogeriatrics, 2023, Volume: 35, Issue:7

    Topics: Alzheimer Disease; Cholinesterase Inhibitors; Cross-Sectional Studies; Dementia; Humans; Lewy Body D

2023
[Antidementia Drug Therapy of Alzheimer's Dementia: Status 2018 and Outlook].
    Deutsche medizinische Wochenschrift (1946), 2019, Volume: 144, Issue:3

    Topics: Alzheimer Disease; Cholinesterase Inhibitors; Dementia, Vascular; Humans; Lewy Body Disease; Memanti

2019
[Treatment of degenerative dementia disorders--who should be treated?].
    Ugeskrift for laeger, 2009, Mar-02, Volume: 171, Issue:10

    Topics: Aged; Alzheimer Disease; Antiparkinson Agents; Cholinesterase Inhibitors; Dementia; Dopamine Agents;

2009
Memantine: a new hope for treatment of Lewy body-related dementias?
    The Lancet. Neurology, 2009, Volume: 8, Issue:7

    Topics: Aged; Brain; Brain Chemistry; Clinical Trials as Topic; Drug Interactions; Excitatory Amino Acid Ant

2009
Clinical practice with anti-dementia drugs: a revised (second) consensus statement from the British Association for Psychopharmacology.
    Journal of psychopharmacology (Oxford, England), 2011, Volume: 25, Issue:8

    Topics: Alzheimer Disease; Animals; Cholinesterase Inhibitors; Dementia; Excitatory Amino Acid Antagonists;

2011
Delusions and hallucinations in dementia with Lewy bodies: worsening with memantine.
    Neurology, 2005, Aug-09, Volume: 65, Issue:3

    Topics: Age of Onset; Aged; Antiparkinson Agents; Brain; Cognition Disorders; Disease Progression; Hallucina

2005
The use of memantine in dementia with Lewy bodies.
    Journal of Alzheimer's disease : JAD, 2005, Volume: 7, Issue:4

    Topics: Aged; Aged, 80 and over; Dopamine Agents; Female; Humans; Lewy Body Disease; Male; Memantine; N-Meth

2005
Exacerbation of Lewy bodies dementia due to memantine.
    Journal of Alzheimer's disease : JAD, 2005, Volume: 8, Issue:3

    Topics: Aged; Alzheimer Disease; Dopamine Agonists; Hallucinations; Humans; Lewy Body Disease; Male; Memanti

2005
Weight-loss associated with anti-dementia drugs in a patient with Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2007, Oct-15, Volume: 22, Issue:13

    Topics: Adverse Drug Reaction Reporting Systems; Aged; Anorexia; Antiparkinson Agents; Cholinesterase Inhibi

2007
Memantine-induced decompensation in a patient with lewy body dementia.
    Annals of the Academy of Medicine, Singapore, 2007, Volume: 36, Issue:8

    Topics: Aged, 80 and over; Antiparkinson Agents; Female; Humans; Lewy Body Disease; Memantine; United States

2007