memantine has been researched along with Brain Edema in 6 studies
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Memantine has demonstrated beneficial effects on several types of brain insults via therapeutic mechanisms mainly related to its activity as a receptor antagonist of N-methyl-d-aspartate." | 5.62 | Memantine protects blood-brain barrier integrity and attenuates neurological deficits through inhibiting nitric oxide synthase ser1412 phosphorylation in intracerebral hemorrhage rats: involvement of peroxynitrite-related matrix metalloproteinase-9/NLRP3 ( Chen, M; Chen, X; Chen, Z; Gao, Z; Huang, H; Mou, Y; Song, M; Xiang, X; Xie, T; Xie, X, 2021) |
| "Patients with brain tumors remain at risk for infections from the perioperative period through many months after treatment, and steroids may mask signs of infection." | 2.52 | Medical management of patients with brain tumors. ( Pruitt, AA, 2015) |
| "Memantine has demonstrated beneficial effects on several types of brain insults via therapeutic mechanisms mainly related to its activity as a receptor antagonist of N-methyl-d-aspartate." | 1.62 | Memantine protects blood-brain barrier integrity and attenuates neurological deficits through inhibiting nitric oxide synthase ser1412 phosphorylation in intracerebral hemorrhage rats: involvement of peroxynitrite-related matrix metalloproteinase-9/NLRP3 ( Chen, M; Chen, X; Chen, Z; Gao, Z; Huang, H; Mou, Y; Song, M; Xiang, X; Xie, T; Xie, X, 2021) |
| "Treatment of cerebral edema could not be investigated because formation of cerebral edema could not be proven statistically." | 1.35 | Effects of memantine and MK-801 on ischemia in an experimental model of acute subdural hematoma. ( Aktan, D; Arica, O; Görgülü, A; Kirin, T; Sencer, A, 2008) |
| "Memantine is a noncompetitive NMDA receptor antagonist and it has been used for the treatment of various cerebral disorders with relatively few side effects." | 1.31 | Reduction of edema and infarction by Memantine and MK-801 after focal cerebral ischaemia and reperfusion in rat. ( Cobanoglu, S; Görgülü, A; Izgi, NI; Kinş, T; Küçük, M; Unal, F; Yanik, B, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, X | 1 |
| Xiang, X | 1 |
| Xie, T | 1 |
| Chen, Z | 1 |
| Mou, Y | 1 |
| Gao, Z | 2 |
| Xie, X | 1 |
| Song, M | 1 |
| Huang, H | 1 |
| Chen, M | 1 |
| Pruitt, AA | 1 |
| Romero Gómez, M | 1 |
| Bautista, JD | 1 |
| Grande, L | 1 |
| Ramos Guerrero, RM | 1 |
| Sánchez Muñoz, D | 1 |
| Creeley, C | 1 |
| Wozniak, DF | 1 |
| Labruyere, J | 1 |
| Taylor, GT | 1 |
| Olney, JW | 1 |
| Sencer, A | 1 |
| Arica, O | 1 |
| Kirin, T | 1 |
| Görgülü, A | 2 |
| Aktan, D | 1 |
| Kinş, T | 1 |
| Cobanoglu, S | 1 |
| Unal, F | 1 |
| Izgi, NI | 1 |
| Yanik, B | 1 |
| Küçük, M | 1 |
2 reviews available for memantine and Brain Edema
| Article | Year |
|---|---|
Medical management of patients with brain tumors.
Topics: Angiogenesis Inhibitors; Anticonvulsants; Brain Edema; Brain Neoplasms; Cognition Disorders; Dopamin | 2015 |
[New concepts in the physiopathology of hepatic encephalopathy and therapeutic prospects].
Topics: Ammonia; Brain; Brain Edema; Dipeptides; Flumazenil; Glutaminase; Glutamine; Hepatic Encephalopathy; | 2004 |
4 other studies available for memantine and Brain Edema
| Article | Year |
|---|---|
Memantine protects blood-brain barrier integrity and attenuates neurological deficits through inhibiting nitric oxide synthase ser1412 phosphorylation in intracerebral hemorrhage rats: involvement of peroxynitrite-related matrix metalloproteinase-9/NLRP3
Topics: Animals; Blood-Brain Barrier; Brain Edema; Cerebral Hemorrhage; Collagenases; Disease Models, Animal | 2021 |
Low doses of memantine disrupt memory in adult rats.
Topics: Alzheimer Disease; Animals; Antiparkinson Agents; Brain Edema; Disease Models, Animal; Excitatory Am | 2006 |
Effects of memantine and MK-801 on ischemia in an experimental model of acute subdural hematoma.
Topics: Animals; Brain Edema; Brain Ischemia; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino | 2008 |
Reduction of edema and infarction by Memantine and MK-801 after focal cerebral ischaemia and reperfusion in rat.
Topics: Animals; Brain Edema; Brain Ischemia; Dizocilpine Maleate; Dopamine Agents; Dose-Response Relationsh | 2000 |