memantine has been researched along with Autism in 13 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "This trial did not demonstrate clinical efficacy of memantine ER in autism; however, the tolerability and safety data were reassuring." | 9.24 | Safety and Efficacy of Memantine in Children with Autism: Randomized, Placebo-Controlled Study and Open-Label Extension. ( Aman, MG; Findling, RL; Gage, AT; Graham, SM; Hardan, AY; Hendren, RL; Hsu, HA; Katz, E; Kehinde-Nelson, O; Melmed, RD; Palmer, RH; Perhach, JL; Trugman, JM, 2017) |
| "Children with autism were randomly allocated to risperidone plus memantine or placebo plus risperidone for a 10-wk, double-blind, placebo-controlled study." | 6.78 | Memantine as adjunctive treatment to risperidone in children with autistic disorder: a randomized, double-blind, placebo-controlled trial. ( Akhondzadeh, S; Asadabadi, M; Ghaleiha, A; Hajiaghaee, R; Hassanzadeh, E; Mohammadi, MR; Shahei, M; Tabrizi, M, 2013) |
| "Memantine treatment of Fmr1-KO CGCs promoted cell adhesion properties." | 5.38 | The therapeutic effect of memantine through the stimulation of synapse formation and dendritic spine maturation in autism and fragile X syndrome. ( Brown, WT; Dobkin, C; Li, X; Malik, M; Sheikh, AM; Wei, H, 2012) |
| "This trial did not demonstrate clinical efficacy of memantine ER in autism; however, the tolerability and safety data were reassuring." | 5.24 | Safety and Efficacy of Memantine in Children with Autism: Randomized, Placebo-Controlled Study and Open-Label Extension. ( Aman, MG; Findling, RL; Gage, AT; Graham, SM; Hardan, AY; Hendren, RL; Hsu, HA; Katz, E; Kehinde-Nelson, O; Melmed, RD; Palmer, RH; Perhach, JL; Trugman, JM, 2017) |
| "In this systematic review we present information relating to the effectiveness and safety of the following interventions: applied behavioural analysis; auditory integration training; Autism Preschool Programme; casein-free diet; chelation; Child's Talk programme; cognitive behavioural therapy; digestive enzymes; EarlyBird programme; facilitated communication; Floortime therapy; gluten-free diet; immunoglobulins; melatonin; memantine; methylphenidate; More Than Words programme; music therapy; olanzapine; omega-3 fish oil; picture exchange communication system; Portage scheme; probiotics; relationship development interventions; risperidone; secretin; selective serotonin reuptake inhibitors (SSRIs); sensory integration training; social stories; social skills training; Son-Rise programme; TEACCH; vitamin A; vitamin B6 (pyridoxine) plus magnesium; and vitamin C." | 4.86 | Autism. ( Parr, J, 2010) |
| "Children with autism were randomly allocated to risperidone plus memantine or placebo plus risperidone for a 10-wk, double-blind, placebo-controlled study." | 2.78 | Memantine as adjunctive treatment to risperidone in children with autistic disorder: a randomized, double-blind, placebo-controlled trial. ( Akhondzadeh, S; Asadabadi, M; Ghaleiha, A; Hajiaghaee, R; Hassanzadeh, E; Mohammadi, MR; Shahei, M; Tabrizi, M, 2013) |
| "TERT-tg mice showed autism spectrum disorder (ASD)-like behavioral phenotypes as well as lowered threshold against electrically induced seizure." | 1.43 | Overexpression of Telomerase Reverse Transcriptase Induces Autism-like Excitatory Phenotypes in Mice. ( Choi, CS; Chung, C; Kim, JW; Kim, KC; Lee, DK; Lee, HW; Park, JE; Rhee, J; Shin, CY; Song, MR; Yoo, HJ, 2016) |
| "Treatment with memantine has significantly attenuated prenatal valproic acid-induced reduction in social interaction, spontaneous alteration, exploratory activity intestinal motility, serotonin levels and prefrontal cortex mitochondrial complex activity." | 1.43 | Memantine ameliorates autistic behavior, biochemistry & blood brain barrier impairments in rats. ( Kumar, H; Sharma, B, 2016) |
| "Memantine treatment of Fmr1-KO CGCs promoted cell adhesion properties." | 1.38 | The therapeutic effect of memantine through the stimulation of synapse formation and dendritic spine maturation in autism and fragile X syndrome. ( Brown, WT; Dobkin, C; Li, X; Malik, M; Sheikh, AM; Wei, H, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 9 (69.23) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Zohny, SM | 1 |
| Habib, MZ | 1 |
| Mohamad, MI | 1 |
| Elayat, WM | 1 |
| Elhossiny, RM | 1 |
| El-Salam, MFA | 1 |
| Hassan, GAM | 1 |
| Aboul-Fotouh, S | 1 |
| Tu, S | 1 |
| Akhtar, MW | 1 |
| Escorihuela, RM | 1 |
| Amador-Arjona, A | 1 |
| Swarup, V | 1 |
| Parker, J | 1 |
| Zaremba, JD | 1 |
| Holland, T | 1 |
| Bansal, N | 1 |
| Holohan, DR | 1 |
| Lopez, K | 1 |
| Ryan, SD | 1 |
| Chan, SF | 1 |
| Yan, L | 1 |
| Zhang, X | 1 |
| Huang, X | 1 |
| Sultan, A | 1 |
| McKercher, SR | 1 |
| Ambasudhan, R | 1 |
| Xu, H | 1 |
| Wang, Y | 1 |
| Geschwind, DH | 1 |
| Roberts, AJ | 1 |
| Terskikh, AV | 1 |
| Rissman, RA | 1 |
| Masliah, E | 1 |
| Lipton, SA | 1 |
| Nakanishi, N | 1 |
| Kim, KC | 1 |
| Rhee, J | 1 |
| Park, JE | 1 |
| Lee, DK | 1 |
| Choi, CS | 1 |
| Kim, JW | 1 |
| Lee, HW | 1 |
| Song, MR | 1 |
| Yoo, HJ | 1 |
| Chung, C | 1 |
| Shin, CY | 1 |
| Aman, MG | 1 |
| Findling, RL | 1 |
| Hardan, AY | 1 |
| Hendren, RL | 1 |
| Melmed, RD | 1 |
| Kehinde-Nelson, O | 1 |
| Hsu, HA | 1 |
| Trugman, JM | 1 |
| Palmer, RH | 1 |
| Graham, SM | 1 |
| Gage, AT | 1 |
| Perhach, JL | 1 |
| Katz, E | 1 |
| Kumar, H | 1 |
| Sharma, B | 1 |
| Nikvarz, N | 1 |
| Alaghband-Rad, J | 1 |
| Tehrani-Doost, M | 1 |
| Alimadadi, A | 1 |
| Ghaeli, P | 1 |
| Webb, S | 1 |
| Parr, J | 1 |
| Wei, H | 1 |
| Dobkin, C | 1 |
| Sheikh, AM | 1 |
| Malik, M | 1 |
| Brown, WT | 1 |
| Li, X | 1 |
| Ghaleiha, A | 1 |
| Asadabadi, M | 1 |
| Mohammadi, MR | 1 |
| Shahei, M | 1 |
| Tabrizi, M | 1 |
| Hajiaghaee, R | 1 |
| Hassanzadeh, E | 1 |
| Akhondzadeh, S | 1 |
| Erickson, CA | 1 |
| Chambers, JE | 1 |
| Niederhofer, H | 2 |
1 review available for memantine and Autism
| Article | Year |
|---|---|
Autism.
Topics: Antipsychotic Agents; Autistic Disorder; Caseins; Double-Blind Method; Humans; Infant; Language Diso | 2010 |
3 trials available for memantine and Autism
| Article | Year |
|---|---|
Safety and Efficacy of Memantine in Children with Autism: Randomized, Placebo-Controlled Study and Open-Label Extension.
Topics: Autistic Disorder; Child; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blin | 2017 |
Memantine as adjunctive treatment to risperidone in children with autistic disorder: a randomized, double-blind, placebo-controlled trial.
Topics: Autistic Disorder; Child; Child, Preschool; Double-Blind Method; Drug Therapy, Combination; Female; | 2013 |
Glutamate antagonists seem to be slightly effective in psychopharmacologic treatment of autism.
Topics: Adolescent; Autistic Disorder; Excitatory Amino Acid Antagonists; Humans; Memantine | 2007 |
9 other studies available for memantine and Autism
| Article | Year |
|---|---|
Memantine/Aripiprazole Combination Alleviates Cognitive Dysfunction in Valproic Acid Rat Model of Autism: Hippocampal CREB/BDNF Signaling and Glutamate Homeostasis.
Topics: Animals; Aripiprazole; Autism Spectrum Disorder; Autistic Disorder; Brain-Derived Neurotrophic Facto | 2023 |
NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism.
Topics: Animals; Autistic Disorder; Behavior, Animal; Biomarkers; Brain; Cell Death; Disease Models, Animal; | 2017 |
Overexpression of Telomerase Reverse Transcriptase Induces Autism-like Excitatory Phenotypes in Mice.
Topics: Animals; Autistic Disorder; Behavior, Animal; Brain; Cell Differentiation; Cells, Cultured; Embryoni | 2016 |
Memantine ameliorates autistic behavior, biochemistry & blood brain barrier impairments in rats.
Topics: Animals; Autistic Disorder; Blood-Brain Barrier; Brain; Disease Models, Animal; Excitatory Amino Aci | 2016 |
Comparing Efficacy and Side Effects of Memantine vs. Risperidone in the Treatment of Autistic Disorder.
Topics: Autistic Disorder; Child; Child, Preschool; Dopamine Agents; Dose-Response Relationship, Drug; Drug- | 2017 |
Drugmakers dance with autism.
Topics: Adult; Animals; Autistic Disorder; Child; Child, Preschool; Clinical Trials, Phase II as Topic; Clin | 2010 |
The therapeutic effect of memantine through the stimulation of synapse formation and dendritic spine maturation in autism and fragile X syndrome.
Topics: Animals; Autistic Disorder; Cell Adhesion; Cell Movement; Cells, Cultured; Cerebellum; Dendritic Spi | 2012 |
Memantine for disruptive behavior in autistic disorder.
Topics: Adult; Attention Deficit and Disruptive Behavior Disorders; Autistic Disorder; Excitatory Amino Acid | 2006 |
Treating autism pharmacologically: also tacrine might improve symptomatology in some cases.
Topics: Adolescent; Adult; Autistic Disorder; Brain Chemistry; Cholinesterase Inhibitors; Excitatory Amino A | 2007 |