memantine has been researched along with Astrocytoma, Grade IV in 8 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Memantine, mefloquine, and metformin can be combined safely with TMZ in patients with newly diagnosed glioblastoma." | 9.30 | Phase 1 lead-in to a phase 2 factorial study of temozolomide plus memantine, mefloquine, and metformin as postradiation adjuvant therapy for newly diagnosed glioblastoma. ( Aldape, KD; Alfred Yung, WK; Conrad, CA; de Groot, JF; Gilbert, MR; Groves, MD; Hess, KR; Loghin, ME; Mammoser, AG; Maraka, S; Melguizo-Gavilanes, I; O'Brien, BJ; Penas-Prado, M; Puduvalli, VK; Sulman, EP; Tremont-Lukats, IW, 2019) |
| "A library of 34 lipophilic sulfonamides based upon the memantine core has been synthesized to identify potential drug candidates to cross the blood-brain barrier and target glioblastoma." | 8.31 | Synthesis and Biological Evaluation of a Library of Sulfonamide Analogs of Memantine to Target Glioblastoma. ( Caudle, JD; Hasin, TR; Kampmeyer, PM; Lamar, AA; Moussa, RN; Philo, JE; Seo, DK; Sheaff, RJ, 2023) |
| "To investigate the effects of metformin, dichloroacetate (DCA), and memantine on T98G and U87-MG human glioblastoma (GBM) cells to target tumor cell metabolism in a multi-directional manner." | 8.02 | Targeting Cancer Cell Metabolism with Metformin, Dichloroacetate and Memantine in Glioblastoma (GBM). ( Albayrak, G; Dere, UA; Emmez, H; Konac, E, 2021) |
| "Glioblastoma is one of the most aggressive malignant primary brain cancer in adults." | 5.46 | Memantine-derived drugs as potential antitumor agents for the treatment of glioblastoma. ( Cacciatore, I; Ciulla, M; Di Stefano, A; Eusepi, P; Fornasari, E; Marinelli, L; Ozdemir, O; Tatar, A; Turkez, H, 2017) |
| "Memantine, mefloquine, and metformin can be combined safely with TMZ in patients with newly diagnosed glioblastoma." | 5.30 | Phase 1 lead-in to a phase 2 factorial study of temozolomide plus memantine, mefloquine, and metformin as postradiation adjuvant therapy for newly diagnosed glioblastoma. ( Aldape, KD; Alfred Yung, WK; Conrad, CA; de Groot, JF; Gilbert, MR; Groves, MD; Hess, KR; Loghin, ME; Mammoser, AG; Maraka, S; Melguizo-Gavilanes, I; O'Brien, BJ; Penas-Prado, M; Puduvalli, VK; Sulman, EP; Tremont-Lukats, IW, 2019) |
| "A library of 34 lipophilic sulfonamides based upon the memantine core has been synthesized to identify potential drug candidates to cross the blood-brain barrier and target glioblastoma." | 4.31 | Synthesis and Biological Evaluation of a Library of Sulfonamide Analogs of Memantine to Target Glioblastoma. ( Caudle, JD; Hasin, TR; Kampmeyer, PM; Lamar, AA; Moussa, RN; Philo, JE; Seo, DK; Sheaff, RJ, 2023) |
| "To investigate the effects of metformin, dichloroacetate (DCA), and memantine on T98G and U87-MG human glioblastoma (GBM) cells to target tumor cell metabolism in a multi-directional manner." | 4.02 | Targeting Cancer Cell Metabolism with Metformin, Dichloroacetate and Memantine in Glioblastoma (GBM). ( Albayrak, G; Dere, UA; Emmez, H; Konac, E, 2021) |
| "Glioblastoma is one of the most aggressive malignant primary brain cancer in adults." | 1.46 | Memantine-derived drugs as potential antitumor agents for the treatment of glioblastoma. ( Cacciatore, I; Ciulla, M; Di Stefano, A; Eusepi, P; Fornasari, E; Marinelli, L; Ozdemir, O; Tatar, A; Turkez, H, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 3 (37.50) | 2.80 |
| Authors | Studies |
|---|---|
| Philo, JE | 1 |
| Caudle, JD | 1 |
| Moussa, RN | 1 |
| Kampmeyer, PM | 1 |
| Hasin, TR | 1 |
| Seo, DK | 1 |
| Sheaff, RJ | 1 |
| Lamar, AA | 1 |
| Albayrak, G | 1 |
| Konac, E | 1 |
| Dere, UA | 1 |
| Emmez, H | 1 |
| Nepali, K | 1 |
| Hsu, TI | 1 |
| Hsieh, CM | 1 |
| Lo, WL | 1 |
| Lai, MJ | 1 |
| Hsu, KC | 1 |
| Lin, TE | 1 |
| Chuang, JY | 1 |
| Liou, JP | 1 |
| Cacciatore, I | 1 |
| Fornasari, E | 1 |
| Marinelli, L | 1 |
| Eusepi, P | 1 |
| Ciulla, M | 1 |
| Ozdemir, O | 1 |
| Tatar, A | 1 |
| Turkez, H | 1 |
| Di Stefano, A | 1 |
| Altinoz, MA | 1 |
| Elmaci, İ | 1 |
| Maraka, S | 2 |
| Groves, MD | 2 |
| Mammoser, AG | 1 |
| Melguizo-Gavilanes, I | 1 |
| Conrad, CA | 1 |
| Tremont-Lukats, IW | 1 |
| Loghin, ME | 1 |
| O'Brien, BJ | 1 |
| Puduvalli, VK | 1 |
| Sulman, EP | 1 |
| Hess, KR | 1 |
| Aldape, KD | 1 |
| Gilbert, MR | 1 |
| de Groot, JF | 1 |
| Alfred Yung, WK | 1 |
| Penas-Prado, M | 2 |
| Nevin, RL | 1 |
1 review available for memantine and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Targeting nitric oxide and NMDA receptor-associated pathways in treatment of high grade glial tumors. Hypotheses for nitro-memantine and nitrones.
Topics: Animals; Antineoplastic Agents; Benzenesulfonates; Brain Neoplasms; Cell Proliferation; Cyclic N-Oxi | 2018 |
1 trial available for memantine and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Phase 1 lead-in to a phase 2 factorial study of temozolomide plus memantine, mefloquine, and metformin as postradiation adjuvant therapy for newly diagnosed glioblastoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant | 2019 |
6 other studies available for memantine and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Synthesis and Biological Evaluation of a Library of Sulfonamide Analogs of Memantine to Target Glioblastoma.
Topics: Animals; Antineoplastic Agents; Biological Transport; Blood-Brain Barrier; Glioblastoma; Humans; Mam | 2023 |
Targeting Cancer Cell Metabolism with Metformin, Dichloroacetate and Memantine in Glioblastoma (GBM).
Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dichloroacetic A | 2021 |
Pragmatic recruitment of memantine as the capping group for the design of HDAC inhibitors: A preliminary attempt to unravel the enigma of glioblastoma.
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Cell Proliferation; Dose-Respo | 2021 |
Memantine-derived drugs as potential antitumor agents for the treatment of glioblastoma.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Antineoplastic Agents; Blood Cells; Blood-Brain Barrier; Brain N | 2017 |
Unexpectedly low rates of neuropsychiatric adverse effects associated with mefloquine repurposed for the treatment of glioblastoma.
Topics: Glioblastoma; Humans; Mefloquine; Memantine; Metformin; Temozolomide | 2019 |
Reply to Unexpectedly low rates of neuropsychiatric adverse effects associated with mefloquine repurposed for the treatment of glioblastoma.
Topics: Glioblastoma; Humans; Mefloquine; Memantine; Metformin; Temozolomide | 2019 |