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memantine and Anxiety

memantine has been researched along with Anxiety in 22 studies

Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.

Research Excerpts

ExcerptRelevanceReference
"Several studies have reported on the beneficial effects of memantine on behavioral and psychological symptoms of dementia (BPSD) in patients with Alzheimer's disease."7.91Memantine ameliorates learning and memory disturbance and the behavioral and psychological symptoms of dementia in thiamine-deficient mice. ( Kashimoto, Y; Kitano, Y; Makino, M; Murasawa, H; Pawlak, A; Takahashi-Ito, K, 2019)
"Chronic amphetamine use results in anxiety-like states after drug cessation."7.79The influence of ionotropic and metabotropic glutamate receptor ligands on anxiety-like effect of amphetamine withdrawal in rats. ( Gibula-Bruzda, E; Koltunowska, D; Kotlinska, JH, 2013)
"Several studies have reported on the beneficial effects of memantine on behavioral and psychological symptoms of dementia (BPSD) in patients with Alzheimer's disease."3.91Memantine ameliorates learning and memory disturbance and the behavioral and psychological symptoms of dementia in thiamine-deficient mice. ( Kashimoto, Y; Kitano, Y; Makino, M; Murasawa, H; Pawlak, A; Takahashi-Ito, K, 2019)
"Chronic amphetamine use results in anxiety-like states after drug cessation."3.79The influence of ionotropic and metabotropic glutamate receptor ligands on anxiety-like effect of amphetamine withdrawal in rats. ( Gibula-Bruzda, E; Koltunowska, D; Kotlinska, JH, 2013)
"Microinjections of glutamic acid, serotonin, and sulpiride in the ventromedial hypothalamus reduced anxiety in an illuminated platform avoidance task in rats, while dopamine, apomorphine, picrotoxin, and memantine increased it."3.71The role of neurochemical mechanisms of ventromedial hypothalamus in various models of anxiety in rats. ( Gordienko, DV; Krivobok, GK; Pankrat'ev, DV; Talalaenko, AN; Zinkovich, II, 2001)
" Safety and tolerability were assessed by the number of withdrawals, adverse events (AEs) and monitoring of vital signs."2.73Safety and tolerability of once-daily versus twice-daily memantine: a randomised, double-blind study in moderate to severe Alzheimer's disease. ( Barker, A; Bayer, A; Inglis, F; Jones, RW; Phul, R, 2007)
"Memantine is a N-methyl-D-aspartate (NMDA) receptor antagonist currently used for moderate-to-severe Alzheimer's disease."1.56Memantine misuse and social networks: A content analysis of Internet self-reports. ( Michel, B; Natter, J, 2020)
"Post-traumatic stress disorder (PTSD) is a psychiatric disorder associated with memories of traumatic experiences."1.51Improvement of PTSD-like behavior by the forgetting effect of hippocampal neurogenesis enhancer memantine in a social defeat stress paradigm. ( Furuyashiki, T; Ishikawa, R; Kida, S; Kitaoka, S; Uchida, C, 2019)
"Memantine is an uncompetitive N-methyl D-aspartate glutamatergic receptors antagonist and has shown beneficial effect on cognitive function especially in Alzheimer's disease."1.42Modification of hippocampal markers of synaptic plasticity by memantine in animal models of acute and repeated restraint stress: implications for memory and behavior. ( Ali, MM; Amin, SN; Attia, YM; El-Aidi, AA; Rashed, LA, 2015)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (31.82)29.6817
2010's9 (40.91)24.3611
2020's6 (27.27)2.80

Authors

AuthorsStudies
Sahraei, M1
Sahraei, H1
Rahimi, M1
Khosravi, M1
Ganjkhani, M1
Meftahi, GH1
Abdo Qaid, EY1
Abdullah, Z1
Zakaria, R1
Long, I1
Siao, WH1
Chang, FY1
Chen, YC1
Toccaceli Blasi, M1
Valletta, M1
Trebbastoni, A1
D'Antonio, F1
Talarico, G1
Campanelli, A1
Sepe Monti, M1
Salati, E1
Gasparini, M1
Buscarnera, S1
Salzillo, M1
Canevelli, M1
Bruno, G1
Natter, J1
Michel, B1
Stazi, M1
Wirths, O1
Zahra, A1
Jiang, J1
Chen, Y1
Long, C1
Yang, L1
Yuanyuan, J1
Junyan, Z1
Cuola, D1
Jingjing, C1
Yuhui, S1
Dan, X1
Wei, D1
Yongsheng, Z1
Makino, M1
Takahashi-Ito, K1
Murasawa, H1
Pawlak, A1
Kashimoto, Y1
Kitano, Y1
Ishikawa, R1
Uchida, C1
Kitaoka, S1
Furuyashiki, T1
Kida, S1
Koltunowska, D1
Gibula-Bruzda, E1
Kotlinska, JH1
Vignisse, J1
Steinbusch, HW1
Grigoriev, V1
Bolkunov, A1
Proshin, A1
Bettendorff, L1
Bachurin, S1
Strekalova, T1
Amin, SN1
El-Aidi, AA1
Ali, MM1
Attia, YM1
Rashed, LA1
Kirby, T1
Kotlinska, J1
Bochenski, M1
Hogan, DB1
Bailey, P1
Black, S1
Carswell, A1
Chertkow, H1
Clarke, B1
Cohen, C1
Fisk, JD1
Forbes, D1
Man-Son-Hing, M1
Lanctôt, K1
Morgan, D1
Thorpe, L1
Clerici, F1
Vanacore, N1
Elia, A1
Spila-Alegiani, S1
Pomati, S1
Da Cas, R1
Raschetti, R1
Mariani, C1
Talalaenko, AN2
Pankrat'ev, DV2
Goncharenko, NV1
Danysz, W1
Jones, RW1
Bayer, A1
Inglis, F1
Barker, A1
Phul, R1
Zdanys, K1
Tampi, RR1
Gordienko, DV1
Zinkovich, II1
Krivobok, GK1

Reviews

2 reviews available for memantine and Anxiety

ArticleYear
Diagnosis and treatment of dementia: 5. Nonpharmacologic and pharmacologic therapy for mild to moderate dementia.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2008, Nov-04, Volume: 179, Issue:10

    Topics: Anxiety; Cholinesterase Inhibitors; Dementia; Dependency, Psychological; Depression; Dopamine Agents

2008
A systematic review of off-label uses of memantine for psychiatric disorders.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, Aug-01, Volume: 32, Issue:6

    Topics: Anxiety; Bipolar Disorder; Bulimia Nervosa; Child; Child Development Disorders, Pervasive; Depressio

2008

Trials

1 trial available for memantine and Anxiety

ArticleYear
Safety and tolerability of once-daily versus twice-daily memantine: a randomised, double-blind study in moderate to severe Alzheimer's disease.
    International journal of geriatric psychiatry, 2007, Volume: 22, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Anxiety; Dopamine Agents; Double-Blind Method; Drug Admi

2007

Other Studies

19 other studies available for memantine and Anxiety

ArticleYear
Anxiogenic and anxiolytic effects of memantine injected into the ventral hippocampus in male stressed mice.
    Journal of complementary & integrative medicine, 2022, Sep-01, Volume: 19, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Hippocampus; Male; Memantine; Mice; N-Methy

2022
Minocycline Attenuates Lipopolysaccharide-Induced Locomotor Deficit and Anxiety-like Behavior and Related Expression of the BDNF/CREB Protein in the Rat Medial Prefrontal Cortex (mPFC).
    International journal of molecular sciences, 2022, Nov-03, Volume: 23, Issue:21

    Topics: Animals; Anxiety; Brain-Derived Neurotrophic Factor; Cyclic AMP Response Element-Binding Protein; Ga

2022
Memantine treats psychosis and agitation associated with Moderna COVID-19 vaccine.
    Schizophrenia research, 2023, Volume: 255

    Topics: 2019-nCoV Vaccine mRNA-1273; Anxiety; COVID-19; Humans; Memantine; Psychotic Disorders

2023
Sundowning in Patients with Dementia: Identification, Prevalence, and Clinical Correlates.
    Journal of Alzheimer's disease : JAD, 2023, Volume: 94, Issue:2

    Topics: Alzheimer Disease; Anxiety; Delirium; Dementia; Humans; Memantine; Prevalence

2023
Memantine misuse and social networks: A content analysis of Internet self-reports.
    Pharmacoepidemiology and drug safety, 2020, Volume: 29, Issue:9

    Topics: Anxiety; Attention Deficit Disorder with Hyperactivity; Depression; Humans; Internet; Memantine; Obs

2020
Chronic Memantine Treatment Ameliorates Behavioral Deficits, Neuron Loss, and Impaired Neurogenesis in a Model of Alzheimer's Disease.
    Molecular neurobiology, 2021, Volume: 58, Issue:1

    Topics: Administration, Oral; Alzheimer Disease; Animals; Anxiety; Behavior, Animal; CA1 Region, Hippocampal

2021
Memantine rescues prenatal citalopram exposure-induced striatal and social abnormalities in mice.
    Experimental neurology, 2018, Volume: 307

    Topics: Animals; Antidepressive Agents, Second-Generation; Anxiety; Citalopram; Corpus Striatum; Excitatory

2018
Memantine attenuated alcohol withdrawal-induced anxiety-like behaviors through down-regulating NR1-CaMKII-ERK signaling pathway.
    Neuroscience letters, 2018, 11-01, Volume: 686

    Topics: Alcoholism; Animals; Anxiety; Anxiety Disorders; Calcium-Calmodulin-Dependent Protein Kinase Type 2;

2018
Memantine ameliorates learning and memory disturbance and the behavioral and psychological symptoms of dementia in thiamine-deficient mice.
    Pharmacology, biochemistry, and behavior, 2019, Volume: 183

    Topics: Administration, Oral; Animals; Anxiety; Behavior, Animal; Biogenic Monoamines; Body Weight; Dementia

2019
Improvement of PTSD-like behavior by the forgetting effect of hippocampal neurogenesis enhancer memantine in a social defeat stress paradigm.
    Molecular brain, 2019, 08-02, Volume: 12, Issue:1

    Topics: Animals; Anxiety; Avoidance Learning; Behavior, Animal; Hippocampus; Male; Memantine; Memory; Mice,

2019
The influence of ionotropic and metabotropic glutamate receptor ligands on anxiety-like effect of amphetamine withdrawal in rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2013, Aug-01, Volume: 45

    Topics: Acamprosate; Amphetamine; Animals; Anxiety; Bridged Bicyclo Compounds; Dose-Response Relationship, D

2013
Concomitant manipulation of murine NMDA- and AMPA-receptors to produce pro-cognitive drug effects in mice.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:2

    Topics: Allyl Compounds; Animals; Anxiety; Avoidance Learning; Brain; Conditioning, Psychological; Dose-Resp

2014
Modification of hippocampal markers of synaptic plasticity by memantine in animal models of acute and repeated restraint stress: implications for memory and behavior.
    Neuromolecular medicine, 2015, Volume: 17, Issue:2

    Topics: Acute Disease; Animals; Anxiety; Behavior, Animal; Biomarkers; Brain-Derived Neurotrophic Factor; Ca

2015
Anxious wait for patients and big pharma.
    The Lancet. Neurology, 2015, Volume: 14, Issue:3

    Topics: Anxiety; Drug Industry; Humans; Jurisprudence; Memantine; New York City; Patents as Topic; Time Fact

2015
The influence of various glutamate receptors antagonists on anxiety-like effect of ethanol withdrawal in a plus-maze test in rats.
    European journal of pharmacology, 2008, Nov-19, Volume: 598, Issue:1-3

    Topics: Acamprosate; Alcohol Deterrents; Animals; Anxiety; Behavior, Animal; Central Nervous System Depressa

2008
Memantine effects on behaviour in moderately severe to severe Alzheimer's disease: a post-marketing surveillance study.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2012, Volume: 33, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Anxiety; Apathy; Depression; Dopamine Agents; Feeding Be

2012
Neurochemical characteristics of the ventromedial hypothalamus in mediating the antiaversive effects of anxiolytics in different models of anxiety.
    Neuroscience and behavioral physiology, 2003, Volume: 33, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-

2003
Society of neuroscience-33rd annual meeting: metabotropic glutamate receptors.
    IDrugs : the investigational drugs journal, 2004, Volume: 7, Issue:1

    Topics: Animals; Antiparkinson Agents; Anxiety; Epilepsy; Excitatory Amino Acid Antagonists; Humans; Hunting

2004
The role of neurochemical mechanisms of ventromedial hypothalamus in various models of anxiety in rats.
    Bulletin of experimental biology and medicine, 2001, Volume: 131, Issue:1

    Topics: Adrenergic Agents; Animals; Anxiety; Apomorphine; Avoidance Learning; Disease Models, Animal; Dopami

2001