memantine has been researched along with Anoxia-Ischemia, Brain in 11 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "7-day old rats were subjected to hypoxia-ischemia (H-I) and treated with combination of memantine and HBO or HH." | 7.83 | Combining hypobaric hypoxia or hyperbaric oxygen postconditioning with memantine reduces neuroprotection in 7-day-old rat hypoxia-ischemia. ( Bratek, E; Gamdzyk, M; Salinska, E; Ziembowicz, A, 2016) |
| "7-day old rats were subjected to hypoxia-ischemia (H-I) and treated with combination of memantine and HBO or HH." | 3.83 | Combining hypobaric hypoxia or hyperbaric oxygen postconditioning with memantine reduces neuroprotection in 7-day-old rat hypoxia-ischemia. ( Bratek, E; Gamdzyk, M; Salinska, E; Ziembowicz, A, 2016) |
| " Since neuronal death following HIE occurs by a cascade of events triggered by activation of glutamate receptors, we used in vitro and in vivo models of HIE to examine whether the AMPA/kainate receptor antagonist topiramate and the NMDA receptor antagonist memantine could exert neuroprotective effects, alone or in combination with hypothermia." | 1.48 | Neuroprotective effects of topiramate and memantine in combination with hypothermia in hypoxic-ischemic brain injury in vitro and in vivo. ( Catarzi, S; Filippi, L; Gerace, E; Guerrini, R; Landucci, E; Pellegrini-Giampietro, DE, 2018) |
| "Memantine is a safe non-competitive NMDA receptor blocker characterized by its low affinity and fast unblocking kinetics." | 1.35 | Neuroprotective effect of memantine combined with topiramate in hypoxic-ischemic brain injury. ( Lin, N; Liu, C; Qiu, Y; Wu, B, 2009) |
| "Memantine (20 mg/kg) was administered immediately after HI in the Memantine-treated group." | 1.33 | [Long-term effects of memantine therapy on neonatal rats with hypoxic-ischemic brain damage]. ( Chen, GY; Chen, HJ; Gao, Y; Qian, LH, 2006) |
| "Memantine was intraperitoneally injected at a dose of 20 mg/kg in neonatal rat models either before (PRE group) or after (POST group) induction of HI." | 1.32 | The regulatory effect of memantine on expression and synthesis of heat shock protein 70 gene in neonatal rat models with cerebral hypoxic ischemia. ( Chen, H; Jiang, M; Liu, Z; Qian, L; Wu, S; Zhou, Z, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (63.64) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Landucci, E | 1 |
| Filippi, L | 1 |
| Gerace, E | 1 |
| Catarzi, S | 1 |
| Guerrini, R | 1 |
| Pellegrini-Giampietro, DE | 1 |
| Juul, SE | 1 |
| Ferriero, DM | 1 |
| Tanashyan, MM | 1 |
| Shabalina, AA | 1 |
| Gnedovskaya, EV | 1 |
| Gan'shina, TS | 1 |
| Kurza, EV | 1 |
| Maslennikov, DV | 1 |
| Mirzoyan, RS | 1 |
| Gamdzyk, M | 1 |
| Ziembowicz, A | 1 |
| Bratek, E | 1 |
| Salinska, E | 1 |
| Manning, SM | 1 |
| Talos, DM | 1 |
| Zhou, C | 1 |
| Selip, DB | 1 |
| Park, HK | 1 |
| Park, CJ | 1 |
| Volpe, JJ | 1 |
| Jensen, FE | 1 |
| Liu, C | 1 |
| Lin, N | 1 |
| Wu, B | 1 |
| Qiu, Y | 1 |
| Chen, H | 1 |
| Liu, Z | 1 |
| Zhou, Z | 1 |
| Jiang, M | 1 |
| Qian, L | 1 |
| Wu, S | 1 |
| Zhang, GQ | 1 |
| Chen, HJ | 2 |
| Jiang, MH | 1 |
| Gao, Y | 1 |
| Qian, LH | 1 |
| Chen, GY | 1 |
| Volbracht, C | 1 |
| van Beek, J | 1 |
| Zhu, C | 1 |
| Blomgren, K | 1 |
| Leist, M | 1 |
| Rimpiläinen, J | 1 |
| Pokela, M | 1 |
| Kiviluoma, K | 1 |
| Vainionpää, V | 1 |
| Hirvonen, J | 1 |
| Ohtonen, P | 1 |
| Jäntti, V | 1 |
| Anttila, V | 1 |
| Heinonen, H | 1 |
| Juvonen, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Amantadine for Neuroenhancement in Acute Patients Study - A Prospective Pilot Proof of Concept Phase IIb Study in Intensive and Intermediate Care Unit Patients[NCT05479032] | Phase 2 | 50 participants (Anticipated) | Interventional | 2022-09-30 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for memantine and Anoxia-Ischemia, Brain
| Article | Year |
|---|---|
Pharmacologic neuroprotective strategies in neonatal brain injury.
Topics: Acetylcysteine; Allopurinol; Antioxidants; Ascorbic Acid; Biopterins; Erythropoietin; Excitatory Ami | 2014 |
10 other studies available for memantine and Anoxia-Ischemia, Brain
| Article | Year |
|---|---|
Neuroprotective effects of topiramate and memantine in combination with hypothermia in hypoxic-ischemic brain injury in vitro and in vivo.
Topics: Animals; Animals, Newborn; Combined Modality Therapy; Disease Models, Animal; Fructose; Hypothermia, | 2018 |
[ANTIPLATELET AND ANTI-ISCHEMIC EFFECTS OF MEMANTINE AND 5-HYDROXYADAMANTAN-2-ONE IN PATIENTS WITH CEREBROVASCULAR PATHOLOGY AND IN EXPERIMENTS].
Topics: Adamantane; Adenosine Diphosphate; Aged; Animals; Animals, Outbred Strains; Blood Platelets; Cells, | 2016 |
Combining hypobaric hypoxia or hyperbaric oxygen postconditioning with memantine reduces neuroprotection in 7-day-old rat hypoxia-ischemia.
Topics: Animals; Animals, Newborn; Apoptosis; CA1 Region, Hippocampal; Disease Models, Animal; Hyperbaric Ox | 2016 |
NMDA receptor blockade with memantine attenuates white matter injury in a rat model of periventricular leukomalacia.
Topics: Animals; Animals, Newborn; Antigens, Differentiation; Biomarkers; Brain; Disease Models, Animal; Exc | 2008 |
Neuroprotective effect of memantine combined with topiramate in hypoxic-ischemic brain injury.
Topics: Animals; Animals, Newborn; Anticonvulsants; Apoptosis; Brain; Brain Infarction; Disease Models, Anim | 2009 |
The regulatory effect of memantine on expression and synthesis of heat shock protein 70 gene in neonatal rat models with cerebral hypoxic ischemia.
Topics: Animals; Female; Gene Expression Regulation; HSP70 Heat-Shock Proteins; Hypoxia-Ischemia, Brain; Mal | 2003 |
[The effects of milkvetch and memantain on the synthesis of cerebral PAF in neonatal rats with hypoxic-ischemic reperfusion].
Topics: Animals; Animals, Newborn; Drugs, Chinese Herbal; Excitatory Amino Acid Antagonists; Hypoxia-Ischemi | 2003 |
[Long-term effects of memantine therapy on neonatal rats with hypoxic-ischemic brain damage].
Topics: Animals; Animals, Newborn; Avoidance Learning; Brain; Excitatory Amino Acid Antagonists; Female; HSP | 2006 |
Neuroprotective properties of memantine in different in vitro and in vivo models of excitotoxicity.
Topics: Animals; Apoptosis; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Hypoxia-Isc | 2006 |
The N-methyl-D-aspartate antagonist memantine has no neuroprotective effect during hypothermic circulatory arrest: a study in the chronic porcine model.
Topics: Animals; Behavior, Animal; Brain; Cardiopulmonary Bypass; Electroencephalography; Female; Glucose; G | 2001 |