memantine and Acute Liver Injury, Drug-Induced studies

memantine and Acute Liver Injury, Drug-Induced

Research Excerpts

Excerpt	Relevance	Reference
" An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems."	1.36	Developing structure-activity relationships for the prediction of hepatotoxicity. ( Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010)

Research

Studies (7)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (14.29)	29.6817
2010's	6 (85.71)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

1 (14.29)

29.6817

2010's

6 (85.71)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Greene, N	1
Fisk, L	1
Naven, RT	1
Note, RR	1
Patel, ML	1
Pelletier, DJ	1
Ekins, S	1
Williams, AJ	1
Xu, JJ	1
Liu, Z	1
Shi, Q	1
Ding, D	1
Kelly, R	1
Fang, H	1
Tong, W	2
Warner, DJ	1
Chen, H	1
Cantin, LD	1
Kenna, JG	1
Stahl, S	1
Walker, CL	1
Noeske, T	1
Chen, M	1
Suzuki, A	1
Thakkar, S	1
Yu, K	1
Hu, C	1
Obara-Michlewska, M	1
Tuszyńska, P	1
Albrecht, J	1
Ferrara, N	1
Corbi, G	1
Capuano, A	1
Filippelli, A	1
Rossi, F	1

Studies

Greene, N

Fisk, L

Naven, RT

Note, RR

Patel, ML

Pelletier, DJ

Ekins, S

Williams, AJ

Xu, JJ

Liu, Z

Shi, Q

Ding, D

Kelly, R

Fang, H

Tong, W

Warner, DJ

Chen, H

Cantin, LD

Kenna, JG

Stahl, S

Walker, CL

Noeske, T

Chen, M

Suzuki, A

Thakkar, S

Yu, K

Hu, C

Obara-Michlewska, M

Tuszyńska, P

Albrecht, J

Ferrara, N

Corbi, G

Capuano, A

Filippelli, A

Rossi, F

Reviews

1 review available for memantine and Acute Liver Injury, Drug-Induced

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr	2016

Article

Year

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Drug discovery today, 2016, Volume: 21, Issue:4

Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr

2016

Other Studies

6 other studies available for memantine and Acute Liver Injury, Drug-Induced

Article	Year
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship;	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS computational biology, 2011, Volume: 7, Issue:12 Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da	2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters	2012
Ammonia upregulates kynurenine aminotransferase II mRNA expression in rat brain: a role for astrocytic NMDA receptors? Metabolic brain disease, 2013, Volume: 28, Issue:2 Topics: Ammonia; Analysis of Variance; Animals; Astrocytes; Brain Chemistry; Carcinogens; Chemical and Drug	2013
Memantine-induced hepatitis with cholestasis in a very elderly patient. Annals of internal medicine, 2008, Apr-15, Volume: 148, Issue:8 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Chemical and Drug Induced Liver Injury; Cholestasis; Fem	2008

Article

Year

Developing structure-activity relationships for the prediction of hepatotoxicity.

Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship;

2010

A predictive ligand-based Bayesian model for human drug-induced liver injury.

Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010

Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

PLoS computational biology, 2011, Volume: 7, Issue:12

Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011

Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.

Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters

2012

Ammonia upregulates kynurenine aminotransferase II mRNA expression in rat brain: a role for astrocytic NMDA receptors?

Metabolic brain disease, 2013, Volume: 28, Issue:2

Topics: Ammonia; Analysis of Variance; Animals; Astrocytes; Brain Chemistry; Carcinogens; Chemical and Drug

2013

Memantine-induced hepatitis with cholestasis in a very elderly patient.

Annals of internal medicine, 2008, Apr-15, Volume: 148, Issue:8

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Chemical and Drug Induced Liver Injury; Cholestasis; Fem

2008