memantine has been researched along with ALS - Amyotrophic Lateral Sclerosis in 9 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Memantine treatment significantly delayed the disease progression and increased the life span of SOD1(G93A) mice, from 121." | 5.33 | Memantine prolongs survival in an amyotrophic lateral sclerosis mouse model. ( Wang, R; Zhang, D, 2005) |
| "Memantine treatment significantly delayed the disease progression and increased the life span of SOD1(G93A) mice, from 121." | 1.33 | Memantine prolongs survival in an amyotrophic lateral sclerosis mouse model. ( Wang, R; Zhang, D, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 4 (44.44) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, A | 1 |
| Liu, C | 1 |
| Ye, W | 2 |
| Huang, D | 1 |
| She, W | 1 |
| Liu, X | 1 |
| Fung, CP | 1 |
| Xu, N | 1 |
| Suen, MC | 1 |
| Sung, HHY | 1 |
| Williams, ID | 1 |
| Zhu, G | 1 |
| Qian, PY | 1 |
| Radulović, S | 1 |
| Sunkara, S | 1 |
| Maurer, C | 1 |
| Leitinger, G | 1 |
| Wong, C | 1 |
| Dakin, RS | 1 |
| Williamson, J | 1 |
| Newton, J | 1 |
| Steven, M | 1 |
| Colville, S | 1 |
| Stavrou, M | 1 |
| Gregory, JM | 1 |
| Elliott, E | 1 |
| Mehta, AR | 1 |
| Chataway, J | 1 |
| Swingler, RJ | 1 |
| Parker, RA | 1 |
| Weir, CJ | 1 |
| Stallard, N | 1 |
| Parmar, MKB | 1 |
| Macleod, MR | 1 |
| Pal, S | 1 |
| Chandran, S | 1 |
| You, FL | 1 |
| Xia, GF | 1 |
| Cai, J | 1 |
| Yáñez, M | 1 |
| Matías-Guiu, J | 1 |
| Arranz-Tagarro, JA | 1 |
| Galán, L | 1 |
| Viña, D | 1 |
| Gómez-Pinedo, U | 1 |
| Vela, A | 1 |
| Guerrero, A | 1 |
| Martínez-Vila, E | 1 |
| García, AG | 1 |
| Blasco, H | 1 |
| Patin, F | 1 |
| Andres, CR | 1 |
| Corcia, P | 1 |
| Gordon, PH | 1 |
| de Carvalho, M | 1 |
| Pinto, S | 1 |
| Costa, J | 1 |
| Evangelista, T | 1 |
| Ohana, B | 1 |
| Pinto, A | 1 |
| Levine, TD | 1 |
| Bowser, R | 1 |
| Hank, N | 1 |
| Saperstein, D | 1 |
| Wang, R | 1 |
| Zhang, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Motor Neurone Disease - Systematic Multi-Arm Adaptive Randomised Trial[NCT04302870] | Phase 2/Phase 3 | 800 participants (Anticipated) | Interventional | 2020-02-27 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for memantine and ALS - Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Digging Deeper: Advancements in Visualization of Inhibitory Synapses in Neurodegenerative Disorders.
Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Brain; Humans; Huntington Disease; Levodo | 2021 |
Amyotrophic Lateral Sclerosis, 2016: existing therapies and the ongoing search for neuroprotection.
Topics: Amyotrophic Lateral Sclerosis; Biomarkers; Clinical Trials as Topic; Frontotemporal Dementia; Humans | 2016 |
3 trials available for memantine and ALS - Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease.
Topics: Amyotrophic Lateral Sclerosis; Double-Blind Method; Humans; Memantine; Motor Neuron Disease; Neurode | 2022 |
A randomized, placebo-controlled trial of memantine for functional disability in amyotrophic lateral sclerosis.
Topics: Adolescent; Adult; Aged; Amyotrophic Lateral Sclerosis; Double-Blind Method; Excitatory Amino Acid A | 2010 |
A pilot trial of memantine and riluzole in ALS: correlation to CSF biomarkers.
Topics: Amyotrophic Lateral Sclerosis; Animals; Biomarkers; Disease Progression; Excitatory Amino Acid Antag | 2010 |
4 other studies available for memantine and ALS - Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Selective
Topics: Amyotrophic Lateral Sclerosis; Animals; Biological Products; C9orf72 Protein; DNA; Drosophila; Front | 2022 |
Behavioural Variant Frontotemporal Dementia due to
Topics: Aged; Amyotrophic Lateral Sclerosis; Cyclins; Frontotemporal Dementia; Humans; Male; Memantine; Muta | 2023 |
The neuroprotection exerted by memantine, minocycline and lithium, against neurotoxicity of CSF from patients with amyotrophic lateral sclerosis, is antagonized by riluzole.
Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Survival; Excitatory Amino Acid Antagonists; Humans; Li | 2014 |
Memantine prolongs survival in an amyotrophic lateral sclerosis mouse model.
Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Excitatory Amino Acid Antagonists; G | 2005 |