melphalan has been researched along with Purpura* in 5 studies
5 other study(ies) available for melphalan and Purpura
| Article | Year |
|---|---|
Improvement of amyloid-related symptoms after autologous stem cell transplantation in a patient with hepatomegaly, macroglossia and purpura.
AL amyloidosis was diagnosed in a 56-year-old woman with spontaneous purpura, macroglossia and hepatomegaly, a serum IgGk monoclonal gammopathy and a 25% plasma cell bone marrow infiltration. She was started on high-dose treatment consisting of four monthly cycles of VID chemotherapy, then underwent a stem cell collection after priming with cyclophosphamide + G-CSF. Myeloablative therapy was with melphalan and busulfan. Hematologic recovery was fast and uncomplicated. At follow-up 22 months from ASCT, the patient shows a complete remission of the clonal plasma cell disorder, normalization of liver size and alkaline phosphatase level and a significant improvement in the signs of vascular and soft tissue amyloid infiltration. Topics: Amyloidosis; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cyclophosphamide; Dexamethasone; Drug Therapy, Combination; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Hepatomegaly; Humans; Idarubicin; Macroglossia; Melphalan; Middle Aged; Purpura; Transplantation, Autologous; Treatment Outcome; Vincristine | 1999 |
Primary amyloidosis and myelomatosis associated with excessive fibrinolytic acitivty.
A case of primary amyloidosis is described in association with Bence-Jones myeloma and increased fibrinolytic activity. Epsilon aminocaproic acid reversed the fibrinolytic activity and clinical improvement was maintained with melphalan and prednisolone. Topics: Aminocaproates; Amyloidosis; Female; Fibrinolysis; Humans; Melphalan; Middle Aged; Multiple Myeloma; Prednisolone; Purpura | 1976 |
Cutaneous signs of cryoparaproteinemia: control with burst alkeran and prednisone.
Topics: Adult; Blood Protein Disorders; Blood Protein Electrophoresis; Blood Proteins; Cold Temperature; Female; Humans; Immune Sera; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Leg; Melphalan; Multiple Myeloma; Precipitin Tests; Prednisone; Purpura; Skin Manifestations | 1973 |
Pseudoleukocytosis due to cryoprotein crystals.
Topics: Cryoglobulins; Crystallization; Diagnosis, Differential; Female; Humans; Immunoglobulin G; Leukocyte Count; Leukocytosis; Melphalan; Middle Aged; Purpura; Skin Ulcer; Temperature | 1973 |
[Ulcero-necrotic purpura revealing Kahler's disease, with macroglobulinemia].
Topics: Female; Humans; Leg Ulcer; Melphalan; Middle Aged; Multiple Myeloma; Necrosis; Prednisone; Purpura; Waldenstrom Macroglobulinemia | 1967 |