melphalan and Mouth-Neoplasms

We report a case of extramedullary plasmacytoma that appeared in an uncharacteristic manner as an ulcerative stomatitis affecting particularly the tongue and buccal mucosa. The lesions were associated with a transient lichenoid skin rash. The literature is reviewed and comparisons made between this tumor and the related plasma cell dyscrasias of multiple myeloma and monoclonal gammopathy.

Topics: Aged; Female; Humans; Immunoglobulin Heavy Chains; Immunoglobulin kappa-Chains; Lichenoid Eruptions; Melphalan; Mouth Neoplasms; Plasmacytoma; Stomatitis; Ulcer

Topics: Diagnosis, Differential; Femoral Fractures; Femoral Neoplasms; Granuloma, Giant Cell; Humans; Jaw Neoplasms; Melphalan; Mouth Neoplasms; Multiple Myeloma; Prednisolone

This work discusses the experience of one surgical team in the Third Surgical Unit at the Republican Teaching Hospital, Baghdad, from 1967 to 1970. 112 patients with advanced malignant lesions in various parts of the body were dealt with. In 84, the intra-arterial route was adopted; in the remaining, systemic administration of cytotoxic agents either singly or in combination was employed. The results are reported in terms of subjective and objective response, and the various complications are discussed.

Topics: Antineoplastic Agents; Breast Neoplasms; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Female; Head and Neck Neoplasms; Humans; Injections, Intra-Arterial; Iraq; Male; Melphalan; Methotrexate; Mouth Neoplasms; Podophyllin; Stomach Neoplasms; Urogenital Neoplasms

Topics: Antineoplastic Agents; Carcinoma; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Leucovorin; Melanoma; Melphalan; Methotrexate; Mouth Neoplasms; Nasopharyngeal Neoplasms; Paranasal Sinus Neoplasms; Sarcoma; Thiotepa; Vinblastine

Topics: Carotid Arteries; Chemotherapy, Cancer, Regional Perfusion; Facial Neoplasms; Humans; Lip Neoplasms; Mandibular Neoplasms; Maxillary Neoplasms; Melphalan; Mouth Neoplasms; Neoplasms; Parotid Neoplasms; Thiotepa; Tongue Neoplasms

Topics: Antimetabolites; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Dactinomycin; Geriatrics; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Melanoma; Melphalan; Methotrexate; Mouth Neoplasms; Neoplasms; Neoplasms, Muscle Tissue; Nitrogen Mustard Compounds; Sarcoma; Toxicology; Triethylenemelamine