melatonin has been researched along with Vitiligo in 8 studies
Vitiligo: A disorder consisting of areas of macular depigmentation, commonly on extensor aspects of extremities, on the face or neck, and in skin folds. Age of onset is often in young adulthood and the condition tends to progress gradually with lesions enlarging and extending until a quiescent state is reached.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A new unifying hypothesis for the aetiology of vitiligo is proposed, in which we postulate that the final destruction of melanocytes in vitiligo results from a cascade of reactions initiated by a disregulation of melanogenesis, caused by activation of the melatonin receptor." | 7.67 | Hypothesis: possible role for the melatonin receptor in vitiligo: discussion paper. ( Bomirski, A; Paus, R; Slominski, A, 1989) |
| "Vitiligo is characterized by a progressive loss of inherited skin color." | 5.38 | Blunted epidermal L-tryptophan metabolism in vitiligo affects immune response and ROS scavenging by Fenton chemistry, part 1: Epidermal H2O2/ONOO(-)-mediated stress abrogates tryptophan hydroxylase and dopa decarboxylase activities, leading to low seroton ( Gibbons, NC; Lüdemann, J; Martinez, A; Rokos, H; Salem, MA; Schallreuter, KU; Slominski, R, 2012) |
| "Vitiligo is characterized by a progressive loss of inherited skin color." | 1.38 | Blunted epidermal L-tryptophan metabolism in vitiligo affects immune response and ROS scavenging by Fenton chemistry, part 1: Epidermal H2O2/ONOO(-)-mediated stress abrogates tryptophan hydroxylase and dopa decarboxylase activities, leading to low seroton ( Gibbons, NC; Lüdemann, J; Martinez, A; Rokos, H; Salem, MA; Schallreuter, KU; Slominski, R, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsiskarishvili, NI | 1 |
| Katsitadze, A | 1 |
| Tsiskarishvili, NV | 1 |
| Tsiskarishvil, Ts | 1 |
| Chitanava, L | 1 |
| Fischer, TW | 1 |
| Slominski, A | 2 |
| Zmijewski, MA | 1 |
| Reiter, RJ | 1 |
| Paus, R | 2 |
| Schallreuter, KU | 1 |
| Salem, MA | 1 |
| Gibbons, NC | 1 |
| Martinez, A | 1 |
| Slominski, R | 1 |
| Lüdemann, J | 1 |
| Rokos, H | 1 |
| Koshevenko, IuN | 1 |
| Frolov, EP | 1 |
| Iyengar, B | 2 |
| Bomirski, A | 1 |
| Renoux, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Role of Peripheral Serotonin in Oculocutaneous Albinism[NCT06138509] | 160 participants (Anticipated) | Observational | 2024-01-31 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for melatonin and Vitiligo
| Article | Year |
|---|---|
Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair.
Topics: Animals; DNA Repair; Free Radical Scavengers; Gene Expression; Hair Follicle; Humans; Melatonin; Rad | 2008 |
[Problems and prospects of vitiligo study].
Topics: Adrenal Cortex; Animals; Autoimmune Diseases; Biogenic Amines; Cyclic AMP; Female; Humans; Melanins; | 1981 |
6 other studies available for melatonin and Vitiligo
| Article | Year |
|---|---|
[MELATONIN CONCENTRATION IN THE BLOOD OF VITILIGO PATIENTS WITH STRESS IN ANAMNESIS].
Topics: Adolescent; Adult; Aged; Female; Humans; Melatonin; Middle Aged; Stress, Psychological; Vitiligo; Yo | 2016 |
Blunted epidermal L-tryptophan metabolism in vitiligo affects immune response and ROS scavenging by Fenton chemistry, part 1: Epidermal H2O2/ONOO(-)-mediated stress abrogates tryptophan hydroxylase and dopa decarboxylase activities, leading to low seroton
Topics: Adult; Calcium Channels, L-Type; Cells, Cultured; Dopa Decarboxylase; Epidermis; Humans; Hydrogen Pe | 2012 |
Indoleamines and the UV-light-sensitive photoperiodic responses of the melanocyte network: a biological calendar?
Topics: Biopsy; Circadian Rhythm; Humans; Immunohistochemistry; Keratosis, Seborrheic; Melanocytes; Melanoma | 1994 |
The UV-responsive melanocyte system: a peripheral network for photoperiodic time measurements. a function of indoleamine expression.
Topics: Cell Cycle; Culture Media; Doxorubicin; Humans; Immunoenzyme Techniques; Melanocytes; Melatonin; Ner | 1998 |
Hypothesis: possible role for the melatonin receptor in vitiligo: discussion paper.
Topics: Humans; Melatonin; Receptors, Melatonin; Receptors, Neurotransmitter; Vitiligo | 1989 |
[Hormonal control of melanin pigmentation].
Topics: Addison Disease; Adrenocorticotropic Hormone; Animals; beta-Lipotropin; Chromatophores; Epinephrine; | 1967 |