Page last updated: 2024-10-19

melatonin and Vitiligo

melatonin has been researched along with Vitiligo in 8 studies

Vitiligo: A disorder consisting of areas of macular depigmentation, commonly on extensor aspects of extremities, on the face or neck, and in skin folds. Age of onset is often in young adulthood and the condition tends to progress gradually with lesions enlarging and extending until a quiescent state is reached.

Research Excerpts

ExcerptRelevanceReference
"A new unifying hypothesis for the aetiology of vitiligo is proposed, in which we postulate that the final destruction of melanocytes in vitiligo results from a cascade of reactions initiated by a disregulation of melanogenesis, caused by activation of the melatonin receptor."7.67Hypothesis: possible role for the melatonin receptor in vitiligo: discussion paper. ( Bomirski, A; Paus, R; Slominski, A, 1989)
"Vitiligo is characterized by a progressive loss of inherited skin color."5.38Blunted epidermal L-tryptophan metabolism in vitiligo affects immune response and ROS scavenging by Fenton chemistry, part 1: Epidermal H2O2/ONOO(-)-mediated stress abrogates tryptophan hydroxylase and dopa decarboxylase activities, leading to low seroton ( Gibbons, NC; Lüdemann, J; Martinez, A; Rokos, H; Salem, MA; Schallreuter, KU; Slominski, R, 2012)
"Vitiligo is characterized by a progressive loss of inherited skin color."1.38Blunted epidermal L-tryptophan metabolism in vitiligo affects immune response and ROS scavenging by Fenton chemistry, part 1: Epidermal H2O2/ONOO(-)-mediated stress abrogates tryptophan hydroxylase and dopa decarboxylase activities, leading to low seroton ( Gibbons, NC; Lüdemann, J; Martinez, A; Rokos, H; Salem, MA; Schallreuter, KU; Slominski, R, 2012)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tsiskarishvili, NI1
Katsitadze, A1
Tsiskarishvili, NV1
Tsiskarishvil, Ts1
Chitanava, L1
Fischer, TW1
Slominski, A2
Zmijewski, MA1
Reiter, RJ1
Paus, R2
Schallreuter, KU1
Salem, MA1
Gibbons, NC1
Martinez, A1
Slominski, R1
Lüdemann, J1
Rokos, H1
Koshevenko, IuN1
Frolov, EP1
Iyengar, B2
Bomirski, A1
Renoux, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Role of Peripheral Serotonin in Oculocutaneous Albinism[NCT06138509]160 participants (Anticipated)Observational2024-01-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for melatonin and Vitiligo

ArticleYear
Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair.
    Experimental dermatology, 2008, Volume: 17, Issue:9

    Topics: Animals; DNA Repair; Free Radical Scavengers; Gene Expression; Hair Follicle; Humans; Melatonin; Rad

2008
[Problems and prospects of vitiligo study].
    Vestnik dermatologii i venerologii, 1981, Issue:10

    Topics: Adrenal Cortex; Animals; Autoimmune Diseases; Biogenic Amines; Cyclic AMP; Female; Humans; Melanins;

1981

Other Studies

6 other studies available for melatonin and Vitiligo

ArticleYear
[MELATONIN CONCENTRATION IN THE BLOOD OF VITILIGO PATIENTS WITH STRESS IN ANAMNESIS].
    Georgian medical news, 2016, Issue:254

    Topics: Adolescent; Adult; Aged; Female; Humans; Melatonin; Middle Aged; Stress, Psychological; Vitiligo; Yo

2016
Blunted epidermal L-tryptophan metabolism in vitiligo affects immune response and ROS scavenging by Fenton chemistry, part 1: Epidermal H2O2/ONOO(-)-mediated stress abrogates tryptophan hydroxylase and dopa decarboxylase activities, leading to low seroton
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, Volume: 26, Issue:6

    Topics: Adult; Calcium Channels, L-Type; Cells, Cultured; Dopa Decarboxylase; Epidermis; Humans; Hydrogen Pe

2012
Indoleamines and the UV-light-sensitive photoperiodic responses of the melanocyte network: a biological calendar?
    Experientia, 1994, Aug-15, Volume: 50, Issue:8

    Topics: Biopsy; Circadian Rhythm; Humans; Immunohistochemistry; Keratosis, Seborrheic; Melanocytes; Melanoma

1994
The UV-responsive melanocyte system: a peripheral network for photoperiodic time measurements. a function of indoleamine expression.
    Acta anatomica, 1998, Volume: 163, Issue:4

    Topics: Cell Cycle; Culture Media; Doxorubicin; Humans; Immunoenzyme Techniques; Melanocytes; Melatonin; Ner

1998
Hypothesis: possible role for the melatonin receptor in vitiligo: discussion paper.
    Journal of the Royal Society of Medicine, 1989, Volume: 82, Issue:9

    Topics: Humans; Melatonin; Receptors, Melatonin; Receptors, Neurotransmitter; Vitiligo

1989
[Hormonal control of melanin pigmentation].
    La Presse medicale, 1967, Dec-02, Volume: 75, Issue:51

    Topics: Addison Disease; Adrenocorticotropic Hormone; Animals; beta-Lipotropin; Chromatophores; Epinephrine;

1967