melatonin has been researched along with Ventricular Dysfunction, Left in 3 studies
Ventricular Dysfunction, Left: A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Although several pharmacological interventions, including melatonin and metformin, have been reported to protect against various cardiovascular diseases, their potential roles in trastuzumab-induced cardiotoxicity remain elusive." | 8.31 | Melatonin and metformin ameliorated trastuzumab-induced cardiotoxicity through the modulation of mitochondrial function and dynamics without reducing its anticancer efficacy. ( Arinno, A; Arunsak, B; Chattipakorn, N; Chattipakorn, SC; Chunchai, T; Kerdphoo, S; Khuanjing, T; Maneechote, C; Nawara, W; Prathumsap, N; Shinlapawittayatorn, K, 2023) |
| "As experimental studies suggest that melatonin is cardioprotective after myocardial infarction (MI), this study sought to investigate the relationships between circulating levels of melatonin and left ventricular (LV) remodelling in patients after acute MI." | 7.78 | Decreased level of melatonin in serum predicts left ventricular remodelling after acute myocardial infarction. ( Abreu-Gonzalez, P; Arroyo-Ucar, E; Dominguez-Rodriguez, A; Reiter, RJ, 2012) |
| " Although several pharmacological interventions, including melatonin and metformin, have been reported to protect against various cardiovascular diseases, their potential roles in trastuzumab-induced cardiotoxicity remain elusive." | 4.31 | Melatonin and metformin ameliorated trastuzumab-induced cardiotoxicity through the modulation of mitochondrial function and dynamics without reducing its anticancer efficacy. ( Arinno, A; Arunsak, B; Chattipakorn, N; Chattipakorn, SC; Chunchai, T; Kerdphoo, S; Khuanjing, T; Maneechote, C; Nawara, W; Prathumsap, N; Shinlapawittayatorn, K, 2023) |
| "As experimental studies suggest that melatonin is cardioprotective after myocardial infarction (MI), this study sought to investigate the relationships between circulating levels of melatonin and left ventricular (LV) remodelling in patients after acute MI." | 3.78 | Decreased level of melatonin in serum predicts left ventricular remodelling after acute myocardial infarction. ( Abreu-Gonzalez, P; Arroyo-Ucar, E; Dominguez-Rodriguez, A; Reiter, RJ, 2012) |
| "Melatonin pretreatment effectively scavenged oxidants and hydroxyl radicals, protecting cardiac function against liver I/R-induced injury." | 1.38 | Preischemic treatment with melatonin attenuates liver reperfusion-induced impairment of cardiac function. ( Chen, KH; Chen, TH; Wang, JJ, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Arinno, A | 2 |
| Maneechote, C | 2 |
| Khuanjing, T | 2 |
| Prathumsap, N | 2 |
| Chunchai, T | 2 |
| Arunsak, B | 2 |
| Nawara, W | 2 |
| Kerdphoo, S | 2 |
| Shinlapawittayatorn, K | 2 |
| Chattipakorn, SC | 2 |
| Chattipakorn, N | 2 |
| Dominguez-Rodriguez, A | 1 |
| Abreu-Gonzalez, P | 1 |
| Arroyo-Ucar, E | 1 |
| Reiter, RJ | 1 |
| Chen, TH | 1 |
| Chen, KH | 1 |
| Wang, JJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Association Between Plasma Melatonin and No-reflow[NCT03306303] | 1,700 participants (Actual) | Observational | 2014-01-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for melatonin and Ventricular Dysfunction, Left
| Article | Year |
|---|---|
Melatonin and metformin ameliorated trastuzumab-induced cardiotoxicity through the modulation of mitochondrial function and dynamics without reducing its anticancer efficacy.
Topics: Animals; Cardiotoxicity; Inflammation; Male; Melatonin; Metformin; Mitochondria; Rats; Rats, Wistar; | 2023 |
Melatonin and metformin ameliorated trastuzumab-induced cardiotoxicity through the modulation of mitochondrial function and dynamics without reducing its anticancer efficacy.
Topics: Animals; Cardiotoxicity; Inflammation; Male; Melatonin; Metformin; Mitochondria; Rats; Rats, Wistar; | 2023 |
Melatonin and metformin ameliorated trastuzumab-induced cardiotoxicity through the modulation of mitochondrial function and dynamics without reducing its anticancer efficacy.
Topics: Animals; Cardiotoxicity; Inflammation; Male; Melatonin; Metformin; Mitochondria; Rats; Rats, Wistar; | 2023 |
Melatonin and metformin ameliorated trastuzumab-induced cardiotoxicity through the modulation of mitochondrial function and dynamics without reducing its anticancer efficacy.
Topics: Animals; Cardiotoxicity; Inflammation; Male; Melatonin; Metformin; Mitochondria; Rats; Rats, Wistar; | 2023 |
Decreased level of melatonin in serum predicts left ventricular remodelling after acute myocardial infarction.
Topics: Aged; Female; Humans; Male; Melatonin; Middle Aged; Myocardial Infarction; Prospective Studies; Ultr | 2012 |
Preischemic treatment with melatonin attenuates liver reperfusion-induced impairment of cardiac function.
Topics: Animals; Antioxidants; Biomarkers; Cardiac Catheterization; Creatine Kinase, MB Form; Disease Models | 2012 |