Page last updated: 2024-10-19

melatonin and Vascular Diseases

melatonin has been researched along with Vascular Diseases in 6 studies

Vascular Diseases: Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.

Research Excerpts

ExcerptRelevanceReference
"Melatonin treatment after ACS did not improve but may have aggravated ED."6.90The effect of melatonin on endothelial dysfunction in patients after acute coronary syndrome: The MEFACS randomized clinical trial. ( Gögenur, I; Isbrand, A; Kleif, J; Lykkesfeldt, J; Madsen, MT; Schou-Pedersen, AV; Zahid, JA, 2019)
"Several pathological conditions, including hypertension, atherosclerosis, diabetes, ischemia/reperfusion injury and nicotine-induced vasculopathy, are associated with vascular endothelial dysfunction characterized by altered secretory output of endothelial cells."3.79Vascular endothelial cells and dysfunctions: role of melatonin. ( Castrezzati, S; Favero, G; Foglio, E; Lonati, C; Rezzani, R; Rodella, LF; Rossini, C, 2013)
"Melatonin treatment after ACS did not improve but may have aggravated ED."2.90The effect of melatonin on endothelial dysfunction in patients after acute coronary syndrome: The MEFACS randomized clinical trial. ( Gögenur, I; Isbrand, A; Kleif, J; Lykkesfeldt, J; Madsen, MT; Schou-Pedersen, AV; Zahid, JA, 2019)
"Melatonin (MLT) plays a critical role in anti-inflammation, but the potential protective effect of melatonin on venous dysfunction induced by IVO has not been revealed."1.72Melatonin Alleviates Venous Dysfunction in a Mouse Model of Iliac Vein Occlusion. ( Du, X; Guo, Z; Lu, S; Ran, F; Xu, D; Xu, X; Zhou, Y, 2022)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Guo, Z1
Du, X1
Zhou, Y1
Xu, D1
Xu, X1
Lu, S1
Ran, F1
Zahid, JA1
Isbrand, A1
Kleif, J1
Schou-Pedersen, AV1
Lykkesfeldt, J1
Madsen, MT1
Gögenur, I1
Wang, Z1
Ni, L1
Wang, J1
Lu, C1
Ren, M1
Han, W1
Liu, C1
Gompper, B1
Bromundt, V1
Orgül, S1
Flammer, J1
Kräuchi, K1
Rodella, LF1
Favero, G1
Foglio, E1
Rossini, C1
Castrezzati, S1
Lonati, C1
Rezzani, R1
Plante, GE1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Melatonin on Progression of Coronary Artery Calcification[NCT03966235]Phase 474 participants (Anticipated)Interventional2019-06-01Recruiting
The Protective Effect of Melatonin in Patients Under Carotid Endarterectomy[NCT03115034]Phase 460 participants (Actual)Interventional2016-06-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for melatonin and Vascular Diseases

ArticleYear
Sleep and vascular disorders.
    Metabolism: clinical and experimental, 2006, Volume: 55, Issue:10 Suppl 2

    Topics: Animals; Humans; Melatonin; Rats; Sleep Wake Disorders; Sympathetic Nervous System; Vascular Disease

2006

Trials

2 trials available for melatonin and Vascular Diseases

ArticleYear
The effect of melatonin on endothelial dysfunction in patients after acute coronary syndrome: The MEFACS randomized clinical trial.
    Journal of pineal research, 2019, Volume: 67, Issue:3

    Topics: Acute Coronary Syndrome; Aged; Double-Blind Method; Endothelium, Vascular; Female; Humans; Hyperemia

2019
The protective effect of melatonin on smoke-induced vascular injury in rats and humans: a randomized controlled trial.
    Journal of pineal research, 2016, Volume: 60, Issue:2

    Topics: Administration, Oral; Adult; Animals; Cell Adhesion Molecules; Endothelin-1; Female; Gene Expression

2016
The protective effect of melatonin on smoke-induced vascular injury in rats and humans: a randomized controlled trial.
    Journal of pineal research, 2016, Volume: 60, Issue:2

    Topics: Administration, Oral; Adult; Animals; Cell Adhesion Molecules; Endothelin-1; Female; Gene Expression

2016
The protective effect of melatonin on smoke-induced vascular injury in rats and humans: a randomized controlled trial.
    Journal of pineal research, 2016, Volume: 60, Issue:2

    Topics: Administration, Oral; Adult; Animals; Cell Adhesion Molecules; Endothelin-1; Female; Gene Expression

2016
The protective effect of melatonin on smoke-induced vascular injury in rats and humans: a randomized controlled trial.
    Journal of pineal research, 2016, Volume: 60, Issue:2

    Topics: Administration, Oral; Adult; Animals; Cell Adhesion Molecules; Endothelin-1; Female; Gene Expression

2016

Other Studies

3 other studies available for melatonin and Vascular Diseases

ArticleYear
Melatonin Alleviates Venous Dysfunction in a Mouse Model of Iliac Vein Occlusion.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Animals; Disease Models, Animal; Humans; Iliac Vein; Melatonin; Mice; RNA, Messenger; Tumor Necrosis

2022
Phase relationship between skin temperature and sleep-wake rhythms in women with vascular dysregulation and controls under real-life conditions.
    Chronobiology international, 2010, Volume: 27, Issue:9-10

    Topics: Adult; Circadian Rhythm; Female; Health Status; Humans; Melatonin; Patient Selection; Saliva; Saliva

2010
Vascular endothelial cells and dysfunctions: role of melatonin.
    Frontiers in bioscience (Elite edition), 2013, 01-01, Volume: 5, Issue:1

    Topics: Atherosclerosis; Diabetes Mellitus; Endothelial Cells; Humans; Hypertension; Melatonin; Nicotine; Re

2013