melatonin has been researched along with Tinnitus in 17 studies
Tinnitus: A nonspecific symptom of hearing disorder characterized by the sensation of buzzing, ringing, clicking, pulsations, and other noises in the ear. Objective tinnitus refers to noises generated from within the ear or adjacent structures that can be heard by other individuals. The term subjective tinnitus is used when the sound is audible only to the affected individual. Tinnitus may occur as a manifestation of COCHLEAR DISEASES; VESTIBULOCOCHLEAR NERVE DISEASES; INTRACRANIAL HYPERTENSION; CRANIOCEREBRAL TRAUMA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine if melatonin improves tinnitus and if this improvement is related to improvement in sleep." | 9.12 | The effects of melatonin on tinnitus and sleep. ( Finnell, JE; Megwalu, UC; Piccirillo, JF, 2006) |
| "Based on the subjective grading, tinnitus perception diminished by 56% in patients treated with sulpiride, by 40% in patients treated with melatonin, by 81% in patients treated with sulpiride plus melatonin, and by 22% in patients treated with placebo." | 9.12 | Sulpiride and melatonin decrease tinnitus perception modulating the auditolimbic dopaminergic pathway. ( Esteban-Ortega, F; Lopez-Gonzalez, MA; Santiago, AM, 2007) |
| "Melatonin has been shown to be useful in the treatment of subjective tinnitus." | 9.08 | Effect of melatonin on tinnitus. ( Olds, MJ; Rosenberg, SI; Rowan, PT; Silverstein, H, 1998) |
| "We performed a review with the purpose to summarise, analyse and discuss the evidence provided by clinical studies evaluating effectiveness of melatonin in the cure of tinnitus." | 8.91 | Clinical pharmacology of melatonin in the treatment of tinnitus: a review. ( Bruno, R; Calapai, F; Calapai, G; Galletti, F; Gangemi, S; Miroddi, M; Navarra, M, 2015) |
| "Melatonin, a hormone produced by the pineal gland, may be a promising treatment option for tinnitus." | 8.90 | Does melatonin have therapeutic use in tinnitus? ( Merrick, L; Peiris, AN; Tanner, M; Youssef, D, 2014) |
| "Melatonin has been proposed as a treatment for tinnitus, especially on the basis of its favourable effects on sleep and its vasoactive and antioxidant properties." | 8.86 | Exploring the reasons why melatonin can improve tinnitus. ( Ferri, GG; Pirodda, A; Raimondi, MC, 2010) |
| "The results of Tinnitus Handicap Inventory (THI) and acufenometry showed a significative improvement of tinnitus after treatment with sulodexide and melatonin." | 7.81 | Medical and surgical treatments for tinnitus: the efficacy of combined treatment with sulodexide and melatonin. ( Agnese, A; Cavallero, A; Delehaye, E; Ferrari, G; Rocchetti, O; Rossi, W; Tombolini, A, 2015) |
| "To determine the correlation between plasma levels of melatonin, vitamin C and vitamin B12 and the presence of tinnitus among elderly subjects with unexplained subjective tinnitus." | 7.78 | The role of plasma melatonin and vitamins C and B12 in the development of idiopathic tinnitus in the elderly. ( Fehintola, FA; Lasisi, AO; Lasisi, TJ, 2012) |
| "Tinnitus is a hearing disorder characterized by the perception of sound without external acoustic stimuli, which is caused by damage to the auditory system in response to excessive levels of noise, ototoxic agents and aging." | 6.61 | Molecular Aspects of Melatonin Treatment in Tinnitus: A Review. ( Ghaznavi, H; Hosseinzadeh, A; Kamali, M; Kamrava, SK; Mehrzadi, S; Moore, BCJ; Reiter, RJ, 2019) |
| " In a dose-response manner, melatonin also reduced vestibular hair cell loss due to gentamicin treatment in explanted utricles of newborn rats." | 6.47 | Drug-mediated ototoxicity and tinnitus: alleviation with melatonin. ( Fuentes-Broto, L; Korkmaz, A; Reiter, RJ; Tan, DX, 2011) |
| " Adults with chronic tinnitus were randomized to 3 mg melatonin or placebo nightly for 30 days followed by a 1-month washout period." | 5.15 | Melatonin: can it stop the ringing? ( Dodson, EE; Dome, C; Holloman, CH; Hurtuk, A; Jacob, A; Welling, DB; Wolfe, K, 2011) |
| "To determine if melatonin improves tinnitus and if this improvement is related to improvement in sleep." | 5.12 | The effects of melatonin on tinnitus and sleep. ( Finnell, JE; Megwalu, UC; Piccirillo, JF, 2006) |
| "Based on the subjective grading, tinnitus perception diminished by 56% in patients treated with sulpiride, by 40% in patients treated with melatonin, by 81% in patients treated with sulpiride plus melatonin, and by 22% in patients treated with placebo." | 5.12 | Sulpiride and melatonin decrease tinnitus perception modulating the auditolimbic dopaminergic pathway. ( Esteban-Ortega, F; Lopez-Gonzalez, MA; Santiago, AM, 2007) |
| "Melatonin has been shown to be useful in the treatment of subjective tinnitus." | 5.08 | Effect of melatonin on tinnitus. ( Olds, MJ; Rosenberg, SI; Rowan, PT; Silverstein, H, 1998) |
| "We performed a review with the purpose to summarise, analyse and discuss the evidence provided by clinical studies evaluating effectiveness of melatonin in the cure of tinnitus." | 4.91 | Clinical pharmacology of melatonin in the treatment of tinnitus: a review. ( Bruno, R; Calapai, F; Calapai, G; Galletti, F; Gangemi, S; Miroddi, M; Navarra, M, 2015) |
| "Melatonin, a hormone produced by the pineal gland, may be a promising treatment option for tinnitus." | 4.90 | Does melatonin have therapeutic use in tinnitus? ( Merrick, L; Peiris, AN; Tanner, M; Youssef, D, 2014) |
| "Melatonin has been proposed as a treatment for tinnitus, especially on the basis of its favourable effects on sleep and its vasoactive and antioxidant properties." | 4.86 | Exploring the reasons why melatonin can improve tinnitus. ( Ferri, GG; Pirodda, A; Raimondi, MC, 2010) |
| "The use of dietary supplements to treat tinnitus is common, particularly with Ginkgo biloba, lipoflavonoids, magnesium, melatonin, vitamin B12, and zinc." | 3.83 | Survey on the Effectiveness of Dietary Supplements to Treat Tinnitus. ( Coelho, C; Gantz, BJ; Hansen, MR; Ji, H; Jun, HJ; Rojas-Roncancio, E; Tao, P; Tyler, R; Wang, TC; Witt, S, 2016) |
| "The results of Tinnitus Handicap Inventory (THI) and acufenometry showed a significative improvement of tinnitus after treatment with sulodexide and melatonin." | 3.81 | Medical and surgical treatments for tinnitus: the efficacy of combined treatment with sulodexide and melatonin. ( Agnese, A; Cavallero, A; Delehaye, E; Ferrari, G; Rocchetti, O; Rossi, W; Tombolini, A, 2015) |
| "To determine the correlation between plasma levels of melatonin, vitamin C and vitamin B12 and the presence of tinnitus among elderly subjects with unexplained subjective tinnitus." | 3.78 | The role of plasma melatonin and vitamins C and B12 in the development of idiopathic tinnitus in the elderly. ( Fehintola, FA; Lasisi, AO; Lasisi, TJ, 2012) |
| "Tinnitus is a hearing disorder characterized by the perception of sound without external acoustic stimuli, which is caused by damage to the auditory system in response to excessive levels of noise, ototoxic agents and aging." | 2.61 | Molecular Aspects of Melatonin Treatment in Tinnitus: A Review. ( Ghaznavi, H; Hosseinzadeh, A; Kamali, M; Kamrava, SK; Mehrzadi, S; Moore, BCJ; Reiter, RJ, 2019) |
| " In a dose-response manner, melatonin also reduced vestibular hair cell loss due to gentamicin treatment in explanted utricles of newborn rats." | 2.47 | Drug-mediated ototoxicity and tinnitus: alleviation with melatonin. ( Fuentes-Broto, L; Korkmaz, A; Reiter, RJ; Tan, DX, 2011) |
| "Melatonin is a neurohormone that is secreted by the pineal gland and known to impact the sleep-wake cycle." | 2.44 | Melatonin. ( Piccirillo, JF, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 11 (64.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hosseinzadeh, A | 1 |
| Kamrava, SK | 1 |
| Moore, BCJ | 1 |
| Reiter, RJ | 2 |
| Ghaznavi, H | 1 |
| Kamali, M | 1 |
| Mehrzadi, S | 1 |
| Lasisi, AO | 1 |
| Fehintola, FA | 1 |
| Lasisi, TJ | 1 |
| Dion, GR | 1 |
| Merrick, L | 1 |
| Youssef, D | 1 |
| Tanner, M | 1 |
| Peiris, AN | 1 |
| Larsen, DG | 1 |
| Ovesen, T | 1 |
| Ferrari, G | 1 |
| Agnese, A | 1 |
| Cavallero, A | 1 |
| Delehaye, E | 1 |
| Rocchetti, O | 1 |
| Rossi, W | 1 |
| Tombolini, A | 1 |
| Miroddi, M | 1 |
| Bruno, R | 1 |
| Galletti, F | 1 |
| Calapai, F | 1 |
| Navarra, M | 1 |
| Gangemi, S | 1 |
| Calapai, G | 1 |
| Coelho, C | 1 |
| Tyler, R | 1 |
| Ji, H | 1 |
| Rojas-Roncancio, E | 1 |
| Witt, S | 1 |
| Tao, P | 1 |
| Jun, HJ | 1 |
| Wang, TC | 1 |
| Hansen, MR | 1 |
| Gantz, BJ | 1 |
| Neri, G | 1 |
| De Stefano, A | 1 |
| Baffa, C | 1 |
| Kulamarva, G | 1 |
| Di Giovanni, P | 1 |
| Petrucci, G | 1 |
| Poliandri, A | 1 |
| Dispenza, F | 1 |
| Citraro, L | 1 |
| Croce, A | 1 |
| Pirodda, A | 1 |
| Raimondi, MC | 1 |
| Ferri, GG | 1 |
| Tan, DX | 1 |
| Korkmaz, A | 1 |
| Fuentes-Broto, L | 1 |
| Hurtuk, A | 1 |
| Dome, C | 1 |
| Holloman, CH | 1 |
| Wolfe, K | 1 |
| Welling, DB | 1 |
| Dodson, EE | 1 |
| Jacob, A | 1 |
| Megwalu, UC | 1 |
| Finnell, JE | 1 |
| Piccirillo, JF | 2 |
| Lopez-Gonzalez, MA | 1 |
| Santiago, AM | 1 |
| Esteban-Ortega, F | 1 |
| Rudin, DO | 1 |
| Rosenberg, SI | 1 |
| Silverstein, H | 1 |
| Rowan, PT | 1 |
| Olds, MJ | 1 |
7 reviews available for melatonin and Tinnitus
| Article | Year |
|---|---|
Molecular Aspects of Melatonin Treatment in Tinnitus: A Review.
Topics: Apoptosis; Autophagy; Clinical Trials as Topic; Humans; Melatonin; Neuronal Plasticity; Nitrosative | 2019 |
Does melatonin have therapeutic use in tinnitus?
Topics: Animals; Antioxidants; Humans; Melatonin; Tinnitus; Treatment Outcome | 2014 |
[Tinnitus guidelines and treatment].
Topics: Acoustic Stimulation; Antidepressive Agents; Central Nervous System Depressants; Cognitive Behaviora | 2014 |
Clinical pharmacology of melatonin in the treatment of tinnitus: a review.
Topics: Antipsychotic Agents; Central Nervous System Depressants; Drug Therapy, Combination; Glycosaminoglyc | 2015 |
Exploring the reasons why melatonin can improve tinnitus.
Topics: Antioxidants; Humans; Melatonin; Muscle Tonus; Muscle, Skeletal; Sleep; Tensor Tympani; Tinnitus | 2010 |
Drug-mediated ototoxicity and tinnitus: alleviation with melatonin.
Topics: Aminoglycosides; Animals; Cisplatin; Controlled Clinical Trials as Topic; Drug-Related Side Effects | 2011 |
Melatonin.
Topics: Animals; Humans; Melatonin; Sleep Wake Disorders; Tinnitus | 2007 |
5 trials available for melatonin and Tinnitus
| Article | Year |
|---|---|
Treatment of central and sensorineural tinnitus with orally administered Melatonin and Sulodexide: personal experience from a randomized controlled study.
Topics: Administration, Oral; Adult; Female; Glycosaminoglycans; Humans; Male; Melatonin; Middle Aged; Prosp | 2009 |
Melatonin: can it stop the ringing?
Topics: Adult; Aged; Aged, 80 and over; Central Nervous System Depressants; Cross-Over Studies; Double-Blind | 2011 |
The effects of melatonin on tinnitus and sleep.
Topics: Adolescent; Adult; Aged; Female; Humans; Male; Melatonin; Middle Aged; Prospective Studies; Sleep; T | 2006 |
Sulpiride and melatonin decrease tinnitus perception modulating the auditolimbic dopaminergic pathway.
Topics: Aged; Auditory Pathways; Dopamine Antagonists; Double-Blind Method; Drug Therapy, Combination; Femal | 2007 |
Effect of melatonin on tinnitus.
Topics: Adult; Aged; Aged, 80 and over; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Melat | 1998 |
5 other studies available for melatonin and Tinnitus
| Article | Year |
|---|---|
The role of plasma melatonin and vitamins C and B12 in the development of idiopathic tinnitus in the elderly.
Topics: Aged; Aged, 80 and over; Ascorbic Acid; Chromatography, High Pressure Liquid; Female; Humans; Male; | 2012 |
Commentary on "does melatonin have therapeutic use in tinnitus?".
Topics: Animals; Humans; Melatonin; Tinnitus | 2014 |
Medical and surgical treatments for tinnitus: the efficacy of combined treatment with sulodexide and melatonin.
Topics: Aged; Anticoagulants; Antioxidants; Drug Therapy, Combination; Female; Glycosaminoglycans; Humans; M | 2015 |
Survey on the Effectiveness of Dietary Supplements to Treat Tinnitus.
Topics: Central Nervous System Depressants; Cross-Sectional Studies; Dietary Supplements; Female; Flavonoids | 2016 |
Glaucoma, "auditory glaucoma", "articular glaucoma" and the third eye.
Topics: Arthritis; Basement Membrane; Cell Membrane Permeability; Glaucoma; Humans; Lipid Metabolism; Melato | 1980 |