melatonin has been researched along with Thyroid Carcinoma, Anaplastic in 2 studies
Thyroid Carcinoma, Anaplastic: An aggressive THYROID GLAND malignancy which generally occurs in IODINE-deficient areas in people with previous thyroid pathology such as GOITER. It is associated with CELL DEDIFFERENTIATION of THYROID CARCINOMA (e.g., FOLLICULAR THYROID CARCINOMA; PAPILLARY THYROID CANCER). Typical initial presentation is a rapidly growing neck mass which upon metastasis is associated with DYSPHAGIA; NECK PAIN; bone pain; DYSPNEA; and NEUROLOGIC DEFICITS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melatonin has enhanced or induced apoptosis in many different cancer cells, however, there has not been any study on the effects of melatonin in the treatment of ATC." | 1.62 | Effects of melatonin on the toxicity and proliferation of human anaplastic thyroid cancer cell line. ( Bahadori, MH; Dabirian, S; Ghorbani-Anarkooli, M; Moladoust, H; Zendedel, A, 2021) |
| "However, the resistance of thyroid cancer cells to dabrafenib limited its therapeutic effect." | 1.56 | Melatonin synergizes BRAF-targeting agent dabrafenib for the treatment of anaplastic thyroid cancer by inhibiting AKT/hTERT signalling. ( Cao, J; Chang, A; Gao, Y; Gu, W; Li, Z; Liao, Y; Tang, R; Wang, H, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liao, Y | 1 |
| Gao, Y | 1 |
| Chang, A | 1 |
| Li, Z | 1 |
| Wang, H | 1 |
| Cao, J | 1 |
| Gu, W | 1 |
| Tang, R | 1 |
| Ghorbani-Anarkooli, M | 1 |
| Dabirian, S | 1 |
| Zendedel, A | 1 |
| Moladoust, H | 1 |
| Bahadori, MH | 1 |
2 other studies available for melatonin and Thyroid Carcinoma, Anaplastic
| Article | Year |
|---|---|
Melatonin synergizes BRAF-targeting agent dabrafenib for the treatment of anaplastic thyroid cancer by inhibiting AKT/hTERT signalling.
Topics: Apoptosis; Caspases; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Do | 2020 |
Effects of melatonin on the toxicity and proliferation of human anaplastic thyroid cancer cell line.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Melat | 2021 |